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Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation.

Angewandte Chemie (International ed. in English)

Wang Y, Richard MA, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G.
PMID: 27276169
Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10431-4. doi: 10.1002/anie.201603931. Epub 2016 Jun 08.

Ferrociphenols (FCs) and their oxidized, electrophilic quinone methide metabolites (FC-QMs) are organometallic compounds related to tamoxifen that exhibit strong antiproliferative properties. To evaluate the reactivity of FC-QMs toward cellular nucleophiles, we studied their reaction with selected thiols. A series...

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Wang Y, Richard MA, Top S, et al. Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation. Angew Chem Int Ed Engl. 2016;55(35):10431-4doi: 10.1002/anie.201603931.
Wang, Y., Richard, M. A., Top, S., Dansette, P. M., Pigeon, P., Vessières, A., Mansuy, D., & Jaouen, G. (2016). Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation. Angewandte Chemie (International ed. in English), 55(35), 10431-4. https://doi.org/10.1002/anie.201603931
Wang, Yong, et al. "Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation." Angewandte Chemie (International ed. in English) vol. 55,35 (2016): 10431-4. doi: https://doi.org/10.1002/anie.201603931
Wang Y, Richard MA, Top S, Dansette PM, Pigeon P, Vessières A, Mansuy D, Jaouen G. Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation. Angew Chem Int Ed Engl. 2016 Aug 22;55(35):10431-4. doi: 10.1002/anie.201603931. Epub 2016 Jun 08. PMID: 27276169.
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Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L.

Evidence-based complementary and alternative medicine : eCAM

Rodriguez Amado JR, Lafourcade Prada A, Escalona Arranz JC, Pérez Rosés R, Morris Quevedo H, Keita H, Puente Zapata E, Pinho Fernandes C, Tavares Carvalho JC.
PMID: 27143986
Evid Based Complement Alternat Med. 2016;2016:3918219. doi: 10.1155/2016/3918219. Epub 2016 Apr 07.

Hepatotoxic chemicals damage liver cells primarily by producing reactive oxygen species. The decoction of the leaves of Tamarindus indica L. is used for liver disorders. In this work we evaluated the hepatoprotective activity of a tablet formulation of this...

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Rodriguez Amado JR, Lafourcade Prada A, Escalona Arranz JC, et al. Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L. Evid Based Complement Alternat Med. 2016;2016:3918219doi: 10.1155/2016/3918219.
Rodriguez Amado, J. R., Lafourcade Prada, A., Escalona Arranz, J. C., Pérez Rosés, R., Morris Quevedo, H., Keita, H., Puente Zapata, E., Pinho Fernandes, C., & Tavares Carvalho, J. C. (2016). Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L. Evidence-based complementary and alternative medicine : eCAM, 20163918219. https://doi.org/10.1155/2016/3918219
Rodriguez Amado, Jesús Rafael, et al. "Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L." Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 3918219. doi: https://doi.org/10.1155/2016/3918219
Rodriguez Amado JR, Lafourcade Prada A, Escalona Arranz JC, Pérez Rosés R, Morris Quevedo H, Keita H, Puente Zapata E, Pinho Fernandes C, Tavares Carvalho JC. Antioxidant and Hepatoprotective Activity of a New Tablets Formulation from Tamarindus indica L. Evid Based Complement Alternat Med. 2016;2016:3918219. doi: 10.1155/2016/3918219. Epub 2016 Apr 07. PMID: 27143986; PMCID: PMC4838804.
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Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata.

Biomolecules & therapeutics

Weon JB, Yun BR, Lee J, Eom MR, Ko HJ, Lee HY, Park DS, Chung HC, Chung JY, Ma CJ.
PMID: 25009706
Biomol Ther (Seoul). 2014 May;22(3):246-53. doi: 10.4062/biomolther.2014.019.

Codonopsis lanceolata has been used as an herbal medicine for several lung inflammatory diseases, such as asthma, tonsillitis, and pharyngitis. Previously, we showed the neuroprotective effect of steamed and fermented C. lanceolata (SFC) in vitro and in vivo. In...

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Weon JB, Yun BR, Lee J, et al. Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata. Biomol Ther (Seoul). 2014;22(3):246-53doi: 10.4062/biomolther.2014.019.
Weon, J. B., Yun, B. R., Lee, J., Eom, M. R., Ko, H. J., Lee, H. Y., Park, D. S., Chung, H. C., Chung, J. Y., & Ma, C. J. (2014). Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata. Biomolecules & therapeutics, 22(3), 246-53. https://doi.org/10.4062/biomolther.2014.019
Weon, Jin Bae, et al. "Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata." Biomolecules & therapeutics vol. 22,3 (2014): 246-53. doi: https://doi.org/10.4062/biomolther.2014.019
Weon JB, Yun BR, Lee J, Eom MR, Ko HJ, Lee HY, Park DS, Chung HC, Chung JY, Ma CJ. Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata. Biomol Ther (Seoul). 2014 May;22(3):246-53. doi: 10.4062/biomolther.2014.019. PMID: 25009706; PMCID: PMC4060076.
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Regulation of Plant Growth, Photosynthesis, Antioxidation and Osmosis by an Arbuscular Mycorrhizal Fungus in Watermelon Seedlings under Well-Watered and Drought Conditions.

Frontiers in plant science

Mo Y, Wang Y, Yang R, Zheng J, Liu C, Li H, Ma J, Zhang Y, Wei C, Zhang X.
PMID: 27242845
Front Plant Sci. 2016 May 11;7:644. doi: 10.3389/fpls.2016.00644. eCollection 2016.

Drought stress has become an increasingly serious environmental issue that influences the growth and production of watermelon. Previous studies found that arbuscular mycorrhizal (AM) colonization improved the fruit yield and water use efficiency (WUE) of watermelon grown under water...

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Mo Y, Wang Y, Yang R, et al. Regulation of Plant Growth, Photosynthesis, Antioxidation and Osmosis by an Arbuscular Mycorrhizal Fungus in Watermelon Seedlings under Well-Watered and Drought Conditions. Front Plant Sci. 2016;7:644doi: 10.3389/fpls.2016.00644.
Mo, Y., Wang, Y., Yang, R., Zheng, J., Liu, C., Li, H., Ma, J., Zhang, Y., Wei, C., & Zhang, X. (2016). Regulation of Plant Growth, Photosynthesis, Antioxidation and Osmosis by an Arbuscular Mycorrhizal Fungus in Watermelon Seedlings under Well-Watered and Drought Conditions. Frontiers in plant science, 7644. https://doi.org/10.3389/fpls.2016.00644
Mo, Yanling, et al. "Regulation of Plant Growth, Photosynthesis, Antioxidation and Osmosis by an Arbuscular Mycorrhizal Fungus in Watermelon Seedlings under Well-Watered and Drought Conditions." Frontiers in plant science vol. 7 (2016): 644. doi: https://doi.org/10.3389/fpls.2016.00644
Mo Y, Wang Y, Yang R, Zheng J, Liu C, Li H, Ma J, Zhang Y, Wei C, Zhang X. Regulation of Plant Growth, Photosynthesis, Antioxidation and Osmosis by an Arbuscular Mycorrhizal Fungus in Watermelon Seedlings under Well-Watered and Drought Conditions. Front Plant Sci. 2016 May 11;7:644. doi: 10.3389/fpls.2016.00644. eCollection 2016. PMID: 27242845; PMCID: PMC4862978.
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Glutathione S-transferase gene GSTM1, gene-gene interaction, and gastric cancer susceptibility: evidence from an updated meta-analysis.

Cancer cell international

Lao X, Peng Q, Lu Y, Li S, Qin X, Chen Z, Chen J.
PMID: 25477765
Cancer Cell Int. 2014 Nov 30;14(1):127. doi: 10.1186/s12935-014-0127-3. eCollection 2014.

BACKGROUND: The null genotype of GSTM1 have been implicated in gastric cancer risk, but numerous individual studies showed mixed, or even conflicting results. Thus, a meta-analysis was performed.RESULTS: We identified 54 individual studies involving 9,322 cases and 15,118 controls...

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Lao X, Peng Q, Lu Y, et al. Glutathione S-transferase gene GSTM1, gene-gene interaction, and gastric cancer susceptibility: evidence from an updated meta-analysis. Cancer Cell Int. 2014;14(1):127doi: 10.1186/s12935-014-0127-3.
Lao, X., Peng, Q., Lu, Y., Li, S., Qin, X., Chen, Z., & Chen, J. (2014). Glutathione S-transferase gene GSTM1, gene-gene interaction, and gastric cancer susceptibility: evidence from an updated meta-analysis. Cancer cell international, 14(1), 127. https://doi.org/10.1186/s12935-014-0127-3
Lao, Xianjun, et al. "Glutathione S-transferase gene GSTM1, gene-gene interaction, and gastric cancer susceptibility: evidence from an updated meta-analysis." Cancer cell international vol. 14,1 (2014): 127. doi: https://doi.org/10.1186/s12935-014-0127-3
Lao X, Peng Q, Lu Y, Li S, Qin X, Chen Z, Chen J. Glutathione S-transferase gene GSTM1, gene-gene interaction, and gastric cancer susceptibility: evidence from an updated meta-analysis. Cancer Cell Int. 2014 Nov 30;14(1):127. doi: 10.1186/s12935-014-0127-3. eCollection 2014. PMID: 25477765; PMCID: PMC4255933.
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Endogenous cross-talk of fungal metabolites.

Frontiers in microbiology

Sheridan KJ, Dolan SK, Doyle S.
PMID: 25601857
Front Microbiol. 2015 Jan 05;5:732. doi: 10.3389/fmicb.2014.00732. eCollection 2014.

Non-ribosomal peptide (NRP) synthesis in fungi requires a ready supply of proteogenic and non-proteogenic amino acids which are subsequently incorporated into the nascent NRP via a thiotemplate mechanism catalyzed by NRP synthetases. Substrate amino acids can be modified prior...

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Sheridan KJ, Dolan SK, Doyle S. Endogenous cross-talk of fungal metabolites. Front Microbiol. 2015;5:732doi: 10.3389/fmicb.2014.00732.
Sheridan, K. J., Dolan, S. K., & Doyle, S. (2014). Endogenous cross-talk of fungal metabolites. Frontiers in microbiology, 5732. https://doi.org/10.3389/fmicb.2014.00732
Sheridan, Kevin J, et al. "Endogenous cross-talk of fungal metabolites." Frontiers in microbiology vol. 5 (2014): 732. doi: https://doi.org/10.3389/fmicb.2014.00732
Sheridan KJ, Dolan SK, Doyle S. Endogenous cross-talk of fungal metabolites. Front Microbiol. 2015 Jan 05;5:732. doi: 10.3389/fmicb.2014.00732. eCollection 2014. PMID: 25601857; PMCID: PMC4283610.
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Effect of multivitamin versus multivitamin-mineral supplementation on metabolic profiles and biomarkers of oxidative stress in pregnant women: a double-blind randomized clinical trial.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Taghizadeh M, Samimi M, Kolahdooz F, Tabassi Z, Jamilian M, Asemi Z.
PMID: 25115164
J Matern Fetal Neonatal Med. 2015 Jul;28(11):1336-1342. doi: 10.3109/14767058.2014.954241. Epub 2014 Sep 10.

OBJECTIVE: This study was designed to determine the favorable effects of received multivitamin versus multivitamin-mineral supplements on metabolic profiles and biomarkers of oxidative stress among Iranian pregnant women.METHODS: This double-blind randomized-controlled clinical trial was conducted among 70 pregnant women,...

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Taghizadeh M, Samimi M, Kolahdooz F, et al. Effect of multivitamin versus multivitamin-mineral supplementation on metabolic profiles and biomarkers of oxidative stress in pregnant women: a double-blind randomized clinical trial. J Matern Fetal Neonatal Med. 2014;28(11):1336-1342doi: 10.3109/14767058.2014.954241.
Taghizadeh, M., Samimi, M., Kolahdooz, F., Tabassi, Z., Jamilian, M., & Asemi, Z. (2015). Effect of multivitamin versus multivitamin-mineral supplementation on metabolic profiles and biomarkers of oxidative stress in pregnant women: a double-blind randomized clinical trial. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 28(11), 1336-1342. https://doi.org/10.3109/14767058.2014.954241
Taghizadeh, Mohsen, et al. "Effect of multivitamin versus multivitamin-mineral supplementation on metabolic profiles and biomarkers of oxidative stress in pregnant women: a double-blind randomized clinical trial." The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians vol. 28,11 (2015): 1336-1342. doi: https://doi.org/10.3109/14767058.2014.954241
Taghizadeh M, Samimi M, Kolahdooz F, Tabassi Z, Jamilian M, Asemi Z. Effect of multivitamin versus multivitamin-mineral supplementation on metabolic profiles and biomarkers of oxidative stress in pregnant women: a double-blind randomized clinical trial. J Matern Fetal Neonatal Med. 2015 Jul;28(11):1336-1342. doi: 10.3109/14767058.2014.954241. Epub 2014 Sep 10. PMID: 25115164.
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Lamivudine-Induced Liver Injury.

Open access Macedonian journal of medical sciences

Olaniyan LW, Maduagwu EN, Akintunde OW, Oluwayelu OO, Brai BI.
PMID: 27275285
Open Access Maced J Med Sci. 2015 Dec 15;3(4):545-50. doi: 10.3889/oamjms.2015.110. Epub 2015 Oct 16.

BACKGROUND: Lamivudine is a nucleoside analogue antiretroviral drug, known for its low toxicity at clinically prescribed dose. However, the toxicity or mechanism of toxicity and target tissue effects during prolonged administration of higher doses were hardly given sufficient laboratory...

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Olaniyan LW, Maduagwu EN, Akintunde OW, et al. Lamivudine-Induced Liver Injury. Open Access Maced J Med Sci. 2015;3(4):545-50doi: 10.3889/oamjms.2015.110.
Olaniyan, L. W., Maduagwu, E. N., Akintunde, O. W., Oluwayelu, O. O., & Brai, B. I. (2015). Lamivudine-Induced Liver Injury. Open access Macedonian journal of medical sciences, 3(4), 545-50. https://doi.org/10.3889/oamjms.2015.110
Olaniyan, Lamidi W B, et al. "Lamivudine-Induced Liver Injury." Open access Macedonian journal of medical sciences vol. 3,4 (2015): 545-50. doi: https://doi.org/10.3889/oamjms.2015.110
Olaniyan LW, Maduagwu EN, Akintunde OW, Oluwayelu OO, Brai BI. Lamivudine-Induced Liver Injury. Open Access Maced J Med Sci. 2015 Dec 15;3(4):545-50. doi: 10.3889/oamjms.2015.110. Epub 2015 Oct 16. PMID: 27275285; PMCID: PMC4877885.
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Biochemical assessment of oxidative status versus liver enzymes in patients with chronic fascioliasis.

Journal of parasitic diseases : official organ of the Indian Society for Parasitology

Kamel HH, Sarhan RM, Saad GA.
PMID: 26688624
J Parasit Dis. 2015 Dec;39(4):628-33. doi: 10.1007/s12639-014-0431-9. Epub 2014 Feb 05.

The aim of this study was to examine the oxidative status in Egyptian patients suffering chronic fascioliasis. The relationship between serum malondialdehyde (MDA) levels, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities was investigated in relation to...

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Kamel HH, Sarhan RM, Saad GA. Biochemical assessment of oxidative status versus liver enzymes in patients with chronic fascioliasis. J Parasit Dis. 2014;39(4):628-33doi: 10.1007/s12639-014-0431-9.
Kamel, H. H., Sarhan, R. M., & Saad, G. A. (2015). Biochemical assessment of oxidative status versus liver enzymes in patients with chronic fascioliasis. Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 39(4), 628-33. https://doi.org/10.1007/s12639-014-0431-9
Kamel, Hanan H, et al. "Biochemical assessment of oxidative status versus liver enzymes in patients with chronic fascioliasis." Journal of parasitic diseases : official organ of the Indian Society for Parasitology vol. 39,4 (2015): 628-33. doi: https://doi.org/10.1007/s12639-014-0431-9
Kamel HH, Sarhan RM, Saad GA. Biochemical assessment of oxidative status versus liver enzymes in patients with chronic fascioliasis. J Parasit Dis. 2015 Dec;39(4):628-33. doi: 10.1007/s12639-014-0431-9. Epub 2014 Feb 05. PMID: 26688624; PMCID: PMC4675571.
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The Thiol Reductase Activity of YUCCA6 Mediates Delayed Leaf Senescence by Regulating Genes Involved in Auxin Redistribution.

Frontiers in plant science

Cha JY, Kim MR, Jung IJ, Kang SB, Park HJ, Kim MG, Yun DJ, Kim WY.
PMID: 27242830
Front Plant Sci. 2016 May 09;7:626. doi: 10.3389/fpls.2016.00626. eCollection 2016.

Auxin, a phytohormone that affects almost every aspect of plant growth and development, is biosynthesized from tryptophan via the tryptamine, indole-3-acetamide, indole-3-pyruvic acid, and indole-3-acetaldoxime pathways. YUCCAs (YUCs), flavin monooxygenase enzymes, catalyze the conversion of indole-3-pyruvic acid (IPA) to...

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Cha JY, Kim MR, Jung IJ, et al. The Thiol Reductase Activity of YUCCA6 Mediates Delayed Leaf Senescence by Regulating Genes Involved in Auxin Redistribution. Front Plant Sci. 2016;7:626doi: 10.3389/fpls.2016.00626.
Cha, J. Y., Kim, M. R., Jung, I. J., Kang, S. B., Park, H. J., Kim, M. G., Yun, D. J., & Kim, W. Y. (2016). The Thiol Reductase Activity of YUCCA6 Mediates Delayed Leaf Senescence by Regulating Genes Involved in Auxin Redistribution. Frontiers in plant science, 7626. https://doi.org/10.3389/fpls.2016.00626
Cha, Joon-Yung, et al. "The Thiol Reductase Activity of YUCCA6 Mediates Delayed Leaf Senescence by Regulating Genes Involved in Auxin Redistribution." Frontiers in plant science vol. 7 (2016): 626. doi: https://doi.org/10.3389/fpls.2016.00626
Cha JY, Kim MR, Jung IJ, Kang SB, Park HJ, Kim MG, Yun DJ, Kim WY. The Thiol Reductase Activity of YUCCA6 Mediates Delayed Leaf Senescence by Regulating Genes Involved in Auxin Redistribution. Front Plant Sci. 2016 May 09;7:626. doi: 10.3389/fpls.2016.00626. eCollection 2016. PMID: 27242830; PMCID: PMC4860463.
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Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia.

Neuropsychiatric disease and treatment

Dietrich-Muszalska A, Kwiatkowska A.
PMID: 24833903
Neuropsychiatr Dis Treat. 2014 May 05;10:703-9. doi: 10.2147/NDT.S60034. eCollection 2014.

Blood platelets are considered to be a peripheral marker in schizophrenia and other psychiatric disorders. Oxidative stress in schizophrenia may be responsible for changes in platelet metabolism and function; therefore, the aim of this study was to examine and...

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Dietrich-Muszalska A, Kwiatkowska A. Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia. Neuropsychiatr Dis Treat. 2014;10:703-9doi: 10.2147/NDT.S60034.
Dietrich-Muszalska, A., & Kwiatkowska, A. (2014). Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia. Neuropsychiatric disease and treatment, 10703-9. https://doi.org/10.2147/NDT.S60034
Dietrich-Muszalska, Anna, and Kwiatkowska, Anna. "Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia." Neuropsychiatric disease and treatment vol. 10 (2014): 703-9. doi: https://doi.org/10.2147/NDT.S60034
Dietrich-Muszalska A, Kwiatkowska A. Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia. Neuropsychiatr Dis Treat. 2014 May 05;10:703-9. doi: 10.2147/NDT.S60034. eCollection 2014. PMID: 24833903; PMCID: PMC4015795.
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Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning.

Arab journal of urology

Shokeir AA, Hussein AM, Awadalla A, Samy A, Abdelaziz A, Khater S, Barakat N.
PMID: 26558061
Arab J Urol. 2012 Dec;10(4):418-24. doi: 10.1016/j.aju.2012.08.003. Epub 2012 Oct 17.

OBJECTIVE: To compare the effect of ischaemic preconditioning (Ipre) vs. ischaemic postconditioning (Ipost) on renal ischaemia/reperfusion (I/R) injury in rats.MATERIALS AND METHODS: In all, 120 male Sprague-Dawley rats were classified into four groups of 30 rats each, designated sham,...

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Shokeir AA, Hussein AM, Awadalla A, et al. Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning. Arab J Urol. 2012;10(4):418-24doi: 10.1016/j.aju.2012.08.003.
Shokeir, A. A., Hussein, A. M., Awadalla, A., Samy, A., Abdelaziz, A., Khater, S., & Barakat, N. (2012). Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning. Arab journal of urology, 10(4), 418-24. https://doi.org/10.1016/j.aju.2012.08.003
Shokeir, Ahmed A, et al. "Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning." Arab journal of urology vol. 10,4 (2012): 418-24. doi: https://doi.org/10.1016/j.aju.2012.08.003
Shokeir AA, Hussein AM, Awadalla A, Samy A, Abdelaziz A, Khater S, Barakat N. Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning. Arab J Urol. 2012 Dec;10(4):418-24. doi: 10.1016/j.aju.2012.08.003. Epub 2012 Oct 17. PMID: 26558061; PMCID: PMC4442954.
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Showing 9985 to 9996 of 12371 entries