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Showing 25 to 36 of 146 entries
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CO.

Angewandte Chemie (International ed. in English)

Seipp CA, Williams NJ, Kidder MK, Custelcean R.
PMID: 28001001
Angew Chem Int Ed Engl. 2017 Jan 19;56(4):1042-1045. doi: 10.1002/anie.201610916. Epub 2016 Dec 21.

Carbon capture and storage is an important strategy for stabilizing the increasing concentration of atmospheric CO

Photoswitchable Nitrogen Superbases: Using Light for Reversible Carbon Dioxide Capture.

Angewandte Chemie (International ed. in English)

Wilm LFB, Das M, Janssen-MĂ¼ller D, MĂ¼ck-Lichtenfeld C, Glorius F, Dielmann F.
PMID: 34694044
Angew Chem Int Ed Engl. 2021 Oct 25; doi: 10.1002/anie.202112344. Epub 2021 Oct 25.

Using light as an external stimulus to alter the reactivity of Lewis bases is an intriguing tool for controlling chemical reactions. Reversible photoreactions associated with pronounced reactivity changes are particularly valuable in this regard. We herein report the first...

Accelerated SuFEx Click Chemistry For Modular Synthesis.

Angewandte Chemie (International ed. in English)

Smedley CJ, Homer JA, Gialelis TL, Barrow AS, Koelln RA, Moses JE.
PMID: 34755436
Angew Chem Int Ed Engl. 2022 Jan 21;61(4):e202112375. doi: 10.1002/anie.202112375. Epub 2021 Dec 07.

SuFEx click chemistry is a powerful method designed for the selective, rapid, and modular synthesis of functional molecules. Classical SuFEx reactions form stable S-O linkages upon exchange of S-F bonds with aryl silyl-ether substrates, and while near-perfect in their...

A versatile one-Pot synthesis of 1,3-substituted guanidines from carbamoyl isothiocyanates.

The Journal of organic chemistry

Linton BR, Carr AJ, Orner BP, Hamilton AD.
PMID: 10814126
J Org Chem. 2000 Mar 10;65(5):1566-8. doi: 10.1021/jo991458q.

No abstract available.

Modified guanidines as potential chiral superbases. 3. Preparation Of 1,4,6-triazabicyclooctene systems and 1,4-disubstituted 2-iminoimidazolidines by the 2-chloro-1,3-dimethylimidazolinium chloride-induced cyclization of guanidines with a hydroxyethyl substituent.

The Journal of organic chemistry

Isobe T, Fukuda K, Yamaguchi K, Seki H, Tokunaga T, Ishikawa T.
PMID: 11073581
J Org Chem. 2000 Nov 17;65(23):7779-85. doi: 10.1021/jo000746f.

Simple preparation methods of modified guanidines have been explored as potential chiral superbases. Thus, 3,7,8-trisubstituted and 3,6,7, 8-tetrasubstituted 1,4,6-triazabicyclooctene systems were prepared from (1S,2S)-1,2-diphenylethylenediamine through stepwise 2-chloro-1, 3-dimethylimidazolinium chloride (DMC)-induced cyclizations of protected thioureas to the corresponding 2-iminoimidazolidines and...

Phase-transfer-catalyzed alkylation of guanidines by alkyl halides under biphasic conditions: a convenient protocol for the synthesis of highly functionalized guanidines.

The Journal of organic chemistry

Powell DA, Ramsden PD, Batey RA.
PMID: 12636395
J Org Chem. 2003 Mar 21;68(6):2300-9. doi: 10.1021/jo0265535.

An operationally straightforward and efficient method for the alkylation of carbamate-protected guanidines with various alkyl halides and mesylates is described. This protocol proceeds via deprotonation of the acidic N-carbamate hydrogen of the guanidine under biphasic conditions using a catalytic...

Versatile solid-phase synthesis of s-arylisothioureas.

Journal of combinatorial chemistry

Katritzky AR, Rogovoy BV, Vvedensky V, Kovalenko K, Forood B.
PMID: 12099846
J Comb Chem. 2002 Jul-Aug;4(4):290-4. doi: 10.1021/cc010065d.

Resin-bound amines 4a-m condense with di(benzotriazol-1-yl)methanimine 6 to give 1H-benzotriazole-1-carboximidamide resins 7a-m, which subsequently react with thiols 9a'-g' followed by cleavage affording nonprotected isothioureas 1aa'-mg' in high yields and with good purities. Analogous reactions with secondary amines activated with...

Recent Advances in Chiral Guanidine-Catalyzed Enantioselective Reactions.

Chemistry, an Asian journal

Chou HC, Leow D, Tan CH.
PMID: 31562680
Chem Asian J. 2019 Nov 04;14(21):3803-3822. doi: 10.1002/asia.201901183. Epub 2019 Oct 17.

Chiral guanidines have been widely used as Brønsted base catalysts and phase transfer catalysts in enantioselective reactions. Due to their amendable structure and powerful catalytic ability, they have attracted much interest. Several new catalysts containing a guanidinium moiety have...

Metal-catalysed reactions enabled by guanidine-type ligands.

Organic & biomolecular chemistry

Cui XY, Tan CH, Leow D.
PMID: 31032829
Org Biomol Chem. 2019 May 15;17(19):4689-4699. doi: 10.1039/c8ob02240b.

Guanidines, which exist widely in nature, have been frequently utilised as strong Brønsted bases in organic chemistry. As ligands, guanidines can have different coordination modes with the metal center. However, the exploitation of these guanidine complexes as catalysts has...

Interaction of Multiple Bonds with NacNacGa: Oxidative Cleavage vs Coupling and Cyclization.

Inorganic chemistry

Kassymbek A, Britten JF, Spasyuk D, Gabidullin B, Nikonov GI.
PMID: 31194533
Inorg Chem. 2019 Jul 01;58(13):8665-8672. doi: 10.1021/acs.inorgchem.9b01005. Epub 2019 Jun 13.

The reactivity of the gallium(I) compound NacNacGa (4) to a variety of unsaturated compounds has been studied. Whereas 4 proved surprisingly unreactive toward olefins, ketones, guanidines, and thioureas, it reacts with isocyanates and carbodiimides to furnish the products of...

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors.

ACS medicinal chemistry letters

Blaszczyk R, Brzezinska J, Dymek B, Stanczak PS, Mazurkiewicz M, Olczak J, Nowicka J, Dzwonek K, Zagozdzon A, Golab J, Golebiowski A.
PMID: 32292546
ACS Med Chem Lett. 2020 Mar 13;11(4):433-438. doi: 10.1021/acsmedchemlett.9b00508. eCollection 2020 Apr 09.

We designed and synthesized a series of arginase inhibitors as derivatives of the well-known 2-(

Enhanced Reactivity in Nucleophilic Acyl Substitution Ion/Ion Reactions Using Triazole-Ester Reagents.

Journal of the American Society for Mass Spectrometry

Bu J, Peng Z, Zhao F, McLuckey SA.
PMID: 28197928
J Am Soc Mass Spectrom. 2017 Jul;28(7):1254-1261. doi: 10.1007/s13361-017-1613-3. Epub 2017 Feb 14.

The acyl substitution reactions between 1-hydroxy-7-aza-benzotriazole (HOAt)/1-hydroxy-benzotriazole (HOBt) ester reagents and nucleophilic side chains on peptides have been demonstrated in the gas phase via ion/ion reactions. The HOAt/HOBt ester reagents were synthesized in solution and ionized via negative nano-electrospray...

Showing 25 to 36 of 146 entries