Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 121 to 128 of 128 entries
Sorted by: Best Match Show Resources per page
Kidney transplantation in highly sensitized recipients.

Kidney research and clinical practice

Park Y, Ko EJ, Chung BH, Yang CW.
PMID: 34233438
Kidney Res Clin Pract. 2021 Sep;40(3):355-370. doi: 10.23876/j.krcp.21.012. Epub 2021 Jun 25.

In kidney transplantation (KT), overcoming donor shortage is particularly challenging in patients with preexisting donor-specific antibodies (DSAs) against human leukocyte antigen (HLA), called HLA-incompatible KT (HLAi KT), carrying the risk of rejection and allograft loss. Thus, it is necessary...

Immunogenetics of heteroclitic recognition of HLA-DQB1 55R eplet specificity by human alloantibody.

Human immunology

Kamoun M, Askar M, Kearns JD, Bui TM, Nguyen M, Brown NK, Duquesnoy RJ.
PMID: 34815108
Hum Immunol. 2021 Nov 20; doi: 10.1016/j.humimm.2021.11.001. Epub 2021 Nov 20.

Heteroclitic antibodies bind to a related antigen with higher affinity than to the immunizing antigen to which they were generated. This uncommon phenomenon is not well characterized for antibodies to HLA antigens. Here we analyzed allosera reactivity from two...

HLA repertoire of 115 UAE nationals infected with SARS-CoV-2.

Human immunology

Alnaqbi H, Tay GK, Jelinek HF, Francis A, Alefishat E, El Haj Chehadeh S, Tahir Saeed A, Hussein M, Laila Salameh, Mahboub BH, Uddin M, Alkaabi N, Alsafar HS.
PMID: 34462158
Hum Immunol. 2021 Aug 21; doi: 10.1016/j.humimm.2021.08.012. Epub 2021 Aug 21.

The class I and class II Human Leucocyte Antigens (HLA) are an integral part of the host adaptive immune system against viral infections. The characterization of HLA allele frequency in the population can play an important role in determining...

Increased Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B in Patients With Kidney Allograft Antibody-mediated Rejection.

Transplantation direct

Clotet-Freixas S, Kotlyar M, McEvoy CM, Pastrello C, Rodríguez-Ramírez S, Farkona S, Cardinal H, Dieudé M, Hébert MJ, Li Y, Famure O, Chen P, Kim SJ, Chan E, Jurisica I, John R, Chruscinski A, Konvalinka A.
PMID: 34557585
Transplant Direct. 2021 Sep 20;7(10):e768. doi: 10.1097/TXD.0000000000001215. eCollection 2021 Oct.

Antibody-mediated rejection (AMR) causes more than 50% of late kidney graft losses. In addition to anti-human leukocyte antigen (HLA) donor-specific antibodies, antibodies against non-HLA antigens are also linked to AMR. Identifying key non-HLA antibodies will improve our understanding of...

Rethinking incompatibility in kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Jackson KR, Segev DL.
PMID: 34464500
Am J Transplant. 2021 Aug 31; doi: 10.1111/ajt.16826. Epub 2021 Aug 31.

Donor/recipient incompatibility in kidney transplantation classically refers to ABO/HLA-incompatibility. Kidney paired donation (KPD) was historically established to circumvent ABO/HLA-incompatibility, with the goal of identifying ABO/HLA-compatible matches. However, there is a broad range of donor factors known to impact recipient...

Post-transplant de novo non donor-specific HLA antibodies are not associated with poor graft outcome in non-sensitized pediatric recipients of kidney transplantation.

Transplant immunology

Cioni M, Comoli P, Tagliamacco A, Innocente A, Basso S, Fontana I, Magnasco A, Trivelli A, Nocco A, Macchiagodena M, Catenacci L, Klersy C, Verrina E, Garibotto G, Ghiggeri GM, Cardillo M, Ginevri F, Nocera A.
PMID: 33610675
Transpl Immunol. 2021 Apr;65:101375. doi: 10.1016/j.trim.2021.101375. Epub 2021 Feb 19.

While de novo donor-specific HLA antibodies (dnDSAs) have a detrimental impact on kidney graft outcome, the clinical significance of de novo non donor-specific antibodies (dnNDSAs) is more controversial. We retrospectively evaluated for Ab development and characteristics of dnNDSAs serially...

Human leukocyte antigens are associated with salivary level of active MMP-8.

Clinical and experimental dental research

Mauramo M, Mauramo E, Sorsa T, Tervahartiala T, Räisänen IT, Waltimo T.
PMID: 34448550
Clin Exp Dent Res. 2021 Oct;7(5):833-839. doi: 10.1002/cre2.419. Epub 2021 Aug 27.

OBJECTIVES: This case control study examined the associations of HLA antigens and periodontitis with the salivary level of active MMP-8 (aMMP-8).MATERIALS AND METHODS: A total of 202 subjects, registered as Swiss bone marrow donors, participated in the study. HLA-A,...

HLA and idiopathic uveitis.

Ocular immunology and inflammation

Palmares J, Castro-Correia J, Coutinho MF, Mendes A, Delgado L.
PMID: 22827212
Ocul Immunol Inflamm. 1993;1(1):179-85. doi: 10.3109/09273949309086557.

Idiopathic uveitis is the most common form of chronic uveitis seen in our area. Characteristically it is a heterogeneous entity in its clinical severity, evolution and therapeutic response, and immune mechanisms are thought to be involved. The phenotype frequencies...

Showing 121 to 128 of 128 entries