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Showing 193 to 196 of 196 entries
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Hemoglobin and Clinical Outcomes in the Vericiguat Global Study in Patients With Heart Failure and Reduced Ejection Fraction (VICTORIA).

Circulation

Ezekowitz JA, Zheng Y, Cohen-Solal A, Melenovský V, Escobedo J, Butler J, Hernandez AF, Lam CSP, O'Connor CM, Pieske B, Ponikowski P, Voors AA, deFilippi C, Westerhout CM, McMullan C, Roessig L, Armstrong PW.
PMID: 34432985
Circulation. 2021 Nov 02;144(18):1489-1499. doi: 10.1161/CIRCULATIONAHA.121.056797. Epub 2021 Aug 25.

BACKGROUND: In the VICTORIA trial (Vericiguat Global Study in Patients with Heart Failure with Reduced Ejection Fraction), anemia occurred more often in patients treated with vericiguat (7.6%) than with placebo (5.7%). We explored the association between vericiguat, randomization hemoglobin,...

Whole-Genome Duplications and the Diversification of the Globin-X Genes of Vertebrates.

Genome biology and evolution

Hoffmann FG, Storz JF, Kuraku S, Vandewege MW, Opazo JC.
PMID: 34480557
Genome Biol Evol. 2021 Oct 01;13(10). doi: 10.1093/gbe/evab205.

Globin-X (GbX) is an enigmatic member of the vertebrate globin gene family with a wide phyletic distribution that spans protostomes and deuterostomes. Unlike canonical globins such as hemoglobins and myoglobins, functional data suggest that GbX does not have a...

Fluoride binding to characteristic heme-pocket centers: Insights into ligand stability.

Journal of inorganic biochemistry

Frankenfield K, Marchany-Rivera D, Flanders KG, Cruz-Balberdy A, Lopez-Garriga J, Cerda JF.
PMID: 34481348
J Inorg Biochem. 2021 Nov;224:111578. doi: 10.1016/j.jinorgbio.2021.111578. Epub 2021 Aug 17.

The studies on the L. pectinata hemoglobins (HbI, HbII, and HbIII) are essential because of their biological roles in hydrogen sulfide transport and metabolism. Variation in the pH could also play a role in the transport of hydrogen sulfide...

Hemoglobins of the Corsico-Sardinian Mouflon (Ovis musimon) and their implications for the origin of Hb A in domestic sheep (Ovis aries).

Annales de genetique et de selection animale

Bunch T, N'guyen T, Lauvergne J.
PMID: 22896114
Ann Genet Sel Anim. 1978;10(4):503-6. doi: 10.1186/1297-9686-10-4-503.

No abstract available.

Showing 193 to 196 of 196 entries