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The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat.

Diabetologia

Steffens AB.
PMID: 27942829
Diabetologia. 1981 Mar;20:411-416. doi: 10.1007/BF00254510.

Rats were provided both with brain cannulas, to permit infusion of fluids in the ventromedial and lateral hypothalamic areas (resp. VMH and LH), and with two heart catheters. In this way infusions of fluids and withdrawal of blood could...

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Steffens AB. The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat. Diabetologia. 1981;20:411-416doi: 10.1007/BF00254510.
Steffens, A. B. (1981). The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat. Diabetologia, 20411-416. https://doi.org/10.1007/BF00254510
Steffens, A B. "The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat." Diabetologia vol. 20 (1981): 411-416. doi: https://doi.org/10.1007/BF00254510
Steffens AB. The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat. Diabetologia. 1981 Mar;20:411-416. doi: 10.1007/BF00254510. PMID: 27942829.
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Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells.

Cardiovascular research

Petsophonsakul P, Burgmaier M, Willems B, Heeneman S, Stadler N, Gremse F, Reith S, Burgmaier K, Kahles F, Marx N, Natour E, Bidar E, Jacobs M, Mees B, Reutelingsperger C, Furmanik M, Schurgers L.
PMID: 34273166
Cardiovasc Res. 2021 Jul 17; doi: 10.1093/cvr/cvab244. Epub 2021 Jul 17.

AIMS: Smokers are at increased risk of cardiovascular events. However, the exact mechanisms through which smoking influences cardiovascular disease resulting in accelerated atherosclerosis and vascular calcification are unknown. The aim of this study was to investigate effects of nicotine...

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Petsophonsakul P, Burgmaier M, Willems B, et al. Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. Cardiovasc Res. 2021;doi: 10.1093/cvr/cvab244.
Petsophonsakul, P., Burgmaier, M., Willems, B., Heeneman, S., Stadler, N., Gremse, F., Reith, S., Burgmaier, K., Kahles, F., Marx, N., Natour, E., Bidar, E., Jacobs, M., Mees, B., Reutelingsperger, C., Furmanik, M., & Schurgers, L. (2021). Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. Cardiovascular research, . https://doi.org/10.1093/cvr/cvab244
Petsophonsakul, Ploingarm, et al. "Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells." Cardiovascular research vol. (2021). doi: https://doi.org/10.1093/cvr/cvab244
Petsophonsakul P, Burgmaier M, Willems B, Heeneman S, Stadler N, Gremse F, Reith S, Burgmaier K, Kahles F, Marx N, Natour E, Bidar E, Jacobs M, Mees B, Reutelingsperger C, Furmanik M, Schurgers L. Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. Cardiovasc Res. 2021 Jul 17; doi: 10.1093/cvr/cvab244. Epub 2021 Jul 17. PMID: 34273166.
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Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits.

Journal of atherosclerosis and thrombosis

Miyazaki C, Shimizu K, Nagasawa Y, Chiba T, Sakuma K, Aimoto M, Yamamoto T, Takahashi M, Sugo N, Takahara A, Shirai K.
PMID: 33473056
J Atheroscler Thromb. 2021 Nov 01;28(11):1241-1249. doi: 10.5551/jat.59451. Epub 2021 Jan 20.

AIM: Stroke is well known to lead to hypertension; nevertheless, the role of vascular function in hypertension remains unclear. In this study, we aimed to clarify the mechanism underlying increased arterial stiffness following stroke.METHODS: The cardio-ankle vascular index (CAVI)...

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Miyazaki C, Shimizu K, Nagasawa Y, et al. Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits. J Atheroscler Thromb. 2021;28(11):1241-1249doi: 10.5551/jat.59451.
Miyazaki, C., Shimizu, K., Nagasawa, Y., Chiba, T., Sakuma, K., Aimoto, M., Yamamoto, T., Takahashi, M., Sugo, N., Takahara, A., & Shirai, K. (2021). Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits. Journal of atherosclerosis and thrombosis, 28(11), 1241-1249. https://doi.org/10.5551/jat.59451
Miyazaki, Chikao, et al. "Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits." Journal of atherosclerosis and thrombosis vol. 28,11 (2021): 1241-1249. doi: https://doi.org/10.5551/jat.59451
Miyazaki C, Shimizu K, Nagasawa Y, Chiba T, Sakuma K, Aimoto M, Yamamoto T, Takahashi M, Sugo N, Takahara A, Shirai K. Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits. J Atheroscler Thromb. 2021 Nov 01;28(11):1241-1249. doi: 10.5551/jat.59451. Epub 2021 Jan 20. PMID: 33473056; PMCID: PMC8592690.
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Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice.

Current research in pharmacology and drug discovery

de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, Dos Santos Ribeiro AEA, da Costa CF, de Oliveira AP, Almeida JRGDS, Jucá DM, Tolentino M, Dos Santos AA, Palheta Junior RC.
PMID: 34909653
Curr Res Pharmacol Drug Discov. 2021 Feb 05;2:100018. doi: 10.1016/j.crphar.2021.100018. eCollection 2021.

Fat burners are a category of nutritional supplements that are claimed to increase the metabolism and promote greater energy expenditure, leading to weight loss. However, little is known about the side effects on gastrointestinal motility. In this study, we...

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de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, et al. Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Curr Res Pharmacol Drug Discov. 2021;2:100018doi: 10.1016/j.crphar.2021.100018.
de Sousa, L. N., Sant'ana, D. S. P., Siqueira Dos Santos, R. G., Dos Santos Ribeiro, A. E. A., da Costa, C. F., de Oliveira, A. P., Almeida, J. R. G. D. S., Jucá, D. M., Tolentino, M., Dos Santos, A. A., & Palheta Junior, R. C. (2021). Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Current research in pharmacology and drug discovery, 2100018. https://doi.org/10.1016/j.crphar.2021.100018
de Sousa, Luciano N, et al. "Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice." Current research in pharmacology and drug discovery vol. 2 (2021): 100018. doi: https://doi.org/10.1016/j.crphar.2021.100018
de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, Dos Santos Ribeiro AEA, da Costa CF, de Oliveira AP, Almeida JRGDS, Jucá DM, Tolentino M, Dos Santos AA, Palheta Junior RC. Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Curr Res Pharmacol Drug Discov. 2021 Feb 05;2:100018. doi: 10.1016/j.crphar.2021.100018. eCollection 2021. PMID: 34909653; PMCID: PMC8663933.
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Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension.

Physiological reports

Ameer OZ, Hildreth CM, Phillips JK.
PMID: 25413325
Physiol Rep. 2014 Nov 20;2(11). doi: 10.14814/phy2.12205. Print 2014 Nov 01.

We examined whether increased sympathetic nerve activity (SNA) accounts for enhanced depressor responses to ganglionic blockade in the Lewis polycystic kidney (LPK) model of chronic kidney disease (CKD) or whether it reflects increased vascular responses to vasodilation (vascular amplifier)....

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Ameer OZ, Hildreth CM, Phillips JK. Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension. Physiol Rep. 2014;2(11)doi: 10.14814/phy2.12205.
Ameer, O. Z., Hildreth, C. M., & Phillips, J. K. (2014). Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension. Physiological reports, 2(11), . https://doi.org/10.14814/phy2.12205
Ameer, Omar Z, et al. "Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension." Physiological reports vol. 2,11 (2014). doi: https://doi.org/10.14814/phy2.12205
Ameer OZ, Hildreth CM, Phillips JK. Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension. Physiol Rep. 2014 Nov 20;2(11). doi: 10.14814/phy2.12205. Print 2014 Nov 01. PMID: 25413325; PMCID: PMC4255812.
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Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants.

Frontiers in endocrinology

De Nardi F, Lefort C, Bréard D, Richomme P, Legros C, Guérineau NC.
PMID: 28993760
Front Endocrinol (Lausanne). 2017 Sep 25;8:248. doi: 10.3389/fendo.2017.00248. eCollection 2017.

Catecholamine (CA) secretion from the adrenal medullary tissue is a key step of the adaptive response triggered by an organism to cope with stress. Whereas molecular and cellular secretory processes have been extensively studied at the single chromaffin cell...

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De Nardi F, Lefort C, Bréard D, et al. Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants. Front Endocrinol (Lausanne). 2017;8:248doi: 10.3389/fendo.2017.00248.
De Nardi, F., Lefort, C., Bréard, D., Richomme, P., Legros, C., & Guérineau, N. C. (2017). Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants. Frontiers in endocrinology, 8248. https://doi.org/10.3389/fendo.2017.00248
De Nardi, Frédéric, et al. "Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants." Frontiers in endocrinology vol. 8 (2017): 248. doi: https://doi.org/10.3389/fendo.2017.00248
De Nardi F, Lefort C, Bréard D, Richomme P, Legros C, Guérineau NC. Monitoring the Secretory Behavior of the Rat Adrenal Medulla by High-Performance Liquid Chromatography-Based Catecholamine Assay from Slice Supernatants. Front Endocrinol (Lausanne). 2017 Sep 25;8:248. doi: 10.3389/fendo.2017.00248. eCollection 2017. PMID: 28993760; PMCID: PMC5622411.
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Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats.

Journal of psychopharmacology (Oxford, England)

Garcha HS, Stolerman IP.
PMID: 22290370
J Psychopharmacol. 1993 Jan;7(1):43-51. doi: 10.1177/026988119300700108.

The discriminative stimulus effects of the nicotine antagonist mecamylamine have been investigated to characterize further its behavioural effects and its interactions with (-)-nicotine. Rats were trained to discriminate the effects of mecamylamine from saline in a two-bar operant conditioning...

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Garcha HS, Stolerman IP. Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats. J Psychopharmacol. 1993;7(1):43-51doi: 10.1177/026988119300700108.
Garcha, H. S., & Stolerman, I. P. (1993). Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats. Journal of psychopharmacology (Oxford, England), 7(1), 43-51. https://doi.org/10.1177/026988119300700108
Garcha, H S, and Stolerman, I P. "Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats." Journal of psychopharmacology (Oxford, England) vol. 7,1 (1993): 43-51. doi: https://doi.org/10.1177/026988119300700108
Garcha HS, Stolerman IP. Discriminative stimulus effects of the nicotine antagonist mecamylamine in rats. J Psychopharmacol. 1993 Jan;7(1):43-51. doi: 10.1177/026988119300700108. PMID: 22290370.
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Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies.

The Malaysian journal of medical sciences : MJMS

Mard SA, Veisi A, Naseri MK, Mikaili P.
PMID: 22135597
Malays J Med Sci. 2011 Jul;18(3):18-26.

BACKGROUND: Terminalia chebula Retz is traditionally used to relieve constipation. The current study was performed to investigate the pharmacological action of aqueous extract of Terminalia chebula seeds (ATC) in vitro and in vivo.METHODS: Terminal pieces of rat ileum were...

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Mard SA, Veisi A, Naseri MK, et al. Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies. Malays J Med Sci. 2011;18(3):18-26
Mard, S. A., Veisi, A., Naseri, M. K., & Mikaili, P. (2011). Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies. The Malaysian journal of medical sciences : MJMS, 18(3), 18-26.
Mard, Seyyed Ali, et al. "Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies." The Malaysian journal of medical sciences : MJMS vol. 18,3 (2011): 18-26.
Mard SA, Veisi A, Naseri MK, Mikaili P. Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies. Malays J Med Sci. 2011 Jul;18(3):18-26. PMID: 22135597; PMCID: PMC3216221.
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Effect of intrathecal administration of ET-1, ET-3 and ET(16-21) on blood pressure and micturition reflex in anesthetized rats.

Neurochemistry international

Giuliani S, Lecci A, Maggi CA, Rovero P, Giachetti A.
PMID: 20504743
Neurochem Int. 1991;18(4):565-9. doi: 10.1016/0197-0186(91)90157-9.

In urethane-anesthetized rats, intrathecal administration of endothelin-1 (ET-1), endothelin-3 (ET-3) (3-100 pmol/rat) or the C-terminal hexapeptide ET(16-21) (10-100 nmol/rat) dose-dependently increased mean blood pressure (MBP) and suppressed the supraspinal micturition reflex (SMR). ET(16-21), at 100 nmol, produced a pressor...

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Giuliani S, Lecci A, Maggi CA, et al. Effect of intrathecal administration of ET-1, ET-3 and ET(16-21) on blood pressure and micturition reflex in anesthetized rats. Neurochem Int. 1991;18(4):565-9doi: 10.1016/0197-0186(91)90157-9.
Giuliani, S., Lecci, A., Maggi, C. A., Rovero, P., & Giachetti, A. (1991). Effect of intrathecal administration of ET-1, ET-3 and ET(16-21) on blood pressure and micturition reflex in anesthetized rats. Neurochemistry international, 18(4), 565-9. https://doi.org/10.1016/0197-0186(91)90157-9
Giuliani, S, et al. "Effect of intrathecal administration of ET-1, ET-3 and ET(16-21) on blood pressure and micturition reflex in anesthetized rats." Neurochemistry international vol. 18,4 (1991): 565-9. doi: https://doi.org/10.1016/0197-0186(91)90157-9
Giuliani S, Lecci A, Maggi CA, Rovero P, Giachetti A. Effect of intrathecal administration of ET-1, ET-3 and ET(16-21) on blood pressure and micturition reflex in anesthetized rats. Neurochem Int. 1991;18(4):565-9. doi: 10.1016/0197-0186(91)90157-9. PMID: 20504743.
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Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats.

Neurochemistry international

Muramatsu M, Arai I, Tamaki J, Hirose H, Fujita A, Aihara H.
PMID: 20493088
Neurochem Int. 1986;8(4):553-8. doi: 10.1016/0197-0186(86)90191-9.

The stress of immobilization in water caused a significant increase in the activity of choline acetyltransferase (CAT) and acetylcholinesterase (AChE), acetylcholine (ACh) content in the stomach and gastric acid secretion, but a decrease of choline content in rats. The...

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Muramatsu M, Arai I, Tamaki J, et al. Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats. Neurochem Int. 1986;8(4):553-8doi: 10.1016/0197-0186(86)90191-9.
Muramatsu, M., Arai, I., Tamaki, J., Hirose, H., Fujita, A., & Aihara, H. (1986). Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats. Neurochemistry international, 8(4), 553-8. https://doi.org/10.1016/0197-0186(86)90191-9
Muramatsu, M, et al. "Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats." Neurochemistry international vol. 8,4 (1986): 553-8. doi: https://doi.org/10.1016/0197-0186(86)90191-9
Muramatsu M, Arai I, Tamaki J, Hirose H, Fujita A, Aihara H. Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats. Neurochem Int. 1986;8(4):553-8. doi: 10.1016/0197-0186(86)90191-9. PMID: 20493088.
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Enhanced sympathetic activity and cardiac sympathetic afferent reflex in rats with heart failure induced by adriamycin.

Journal of biomedical research

Zhang S, Zhang F, Sun H, Zhou Y, Han Y.
PMID: 23554781
J Biomed Res. 2012 Nov;26(6):425-31. doi: 10.7555/JBR.26.20120035. Epub 2012 Oct 19.

Our previous studies have shown that the cardiac sympathetic afferent reflex is enhanced in rats with chronic heart failure (CHF) induced by coronary artery ligation and contributes to the over-excitation of sympathetic activity. We sought to determine whether sympathetic...

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Zhang S, Zhang F, Sun H, et al. Enhanced sympathetic activity and cardiac sympathetic afferent reflex in rats with heart failure induced by adriamycin. J Biomed Res. 2012;26(6):425-31doi: 10.7555/JBR.26.20120035.
Zhang, S., Zhang, F., Sun, H., Zhou, Y., & Han, Y. (2012). Enhanced sympathetic activity and cardiac sympathetic afferent reflex in rats with heart failure induced by adriamycin. Journal of biomedical research, 26(6), 425-31. https://doi.org/10.7555/JBR.26.20120035
Zhang, Shujuan, et al. "Enhanced sympathetic activity and cardiac sympathetic afferent reflex in rats with heart failure induced by adriamycin." Journal of biomedical research vol. 26,6 (2012): 425-31. doi: https://doi.org/10.7555/JBR.26.20120035
Zhang S, Zhang F, Sun H, Zhou Y, Han Y. Enhanced sympathetic activity and cardiac sympathetic afferent reflex in rats with heart failure induced by adriamycin. J Biomed Res. 2012 Nov;26(6):425-31. doi: 10.7555/JBR.26.20120035. Epub 2012 Oct 19. PMID: 23554781; PMCID: PMC3597045.
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Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice.

Current research in pharmacology and drug discovery

de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, Dos Santos Ribeiro AEA, da Costa CF, de Oliveira AP, Almeida JRGDS, Jucá DM, Tolentino M, Dos Santos AA, Palheta Junior RC.
PMID: 34909653
Curr Res Pharmacol Drug Discov. 2021 Feb 05;2:100018. doi: 10.1016/j.crphar.2021.100018. eCollection 2021.

Fat burners are a category of nutritional supplements that are claimed to increase the metabolism and promote greater energy expenditure, leading to weight loss. However, little is known about the side effects on gastrointestinal motility. In this study, we...

Cite
de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, et al. Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Curr Res Pharmacol Drug Discov. 2021;2:100018doi: 10.1016/j.crphar.2021.100018.
de Sousa, L. N., Sant'ana, D. S. P., Siqueira Dos Santos, R. G., Dos Santos Ribeiro, A. E. A., da Costa, C. F., de Oliveira, A. P., Almeida, J. R. G. D. S., Jucá, D. M., Tolentino, M., Dos Santos, A. A., & Palheta Junior, R. C. (2021). Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Current research in pharmacology and drug discovery, 2100018. https://doi.org/10.1016/j.crphar.2021.100018
de Sousa, Luciano N, et al. "Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice." Current research in pharmacology and drug discovery vol. 2 (2021): 100018. doi: https://doi.org/10.1016/j.crphar.2021.100018
de Sousa LN, Sant'ana DSP, Siqueira Dos Santos RG, Dos Santos Ribeiro AEA, da Costa CF, de Oliveira AP, Almeida JRGDS, Jucá DM, Tolentino M, Dos Santos AA, Palheta Junior RC. Involvement of serotonergic pathways in gastric dysmotility induced by fat burning nutritional supplements in mice. Curr Res Pharmacol Drug Discov. 2021 Feb 05;2:100018. doi: 10.1016/j.crphar.2021.100018. eCollection 2021. PMID: 34909653; PMCID: PMC8663933.
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