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Showing 181 to 190 of 190 entries
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Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism.

Iranian journal of pharmaceutical research : IJPR

Zhao DH, Wang YC, Zheng LW, Liu BY, Guan LP.
PMID: 29755551
Iran J Pharm Res. 2018;17(1):193-201.

DHIPC (2,4-dichloro-2´-hydroxyl-4´,6´-diisoprenyloxychalcone) is a new chalcone compound. In this study, its antidepressant-like activity of compound DHIPC was evaluated by the forced swimming test and the tail suspension test in mice. The results showed that DHIPC significantly reduced the immobility...

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Zhao DH, Wang YC, Zheng LW, et al. Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism. Iran J Pharm Res. 2018;17(1):193-201
Zhao, D. H., Wang, Y. C., Zheng, L. W., Liu, B. Y., & Guan, L. P. (2018). Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism. Iranian journal of pharmaceutical research : IJPR, 17(1), 193-201.
Zhao, Dong-Hai, et al. "Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism." Iranian journal of pharmaceutical research : IJPR vol. 17,1 (2018): 193-201.
Zhao DH, Wang YC, Zheng LW, Liu BY, Guan LP. Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism. Iran J Pharm Res. 2018;17(1):193-201. PMID: 29755551; PMCID: PMC5937090.
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The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review.

Metabolites

Schjødt MS, Gürdeniz G, Chawes B.
PMID: 33339279
Metabolites. 2020 Dec 16;10(12). doi: 10.3390/metabo10120511.

Asthma, allergic rhinitis, food allergy, and atopic dermatitis are common childhood diseases with several different underlying mechanisms, i.e., endotypes of disease. Metabolomics has the potential to identify disease endotypes, which could beneficially promote personalized prevention and treatment. Here, we...

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Schjødt MS, Gürdeniz G, Chawes B. The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review. Metabolites. 2020;10(12)doi: 10.3390/metabo10120511.
Schjødt, M. S., Gürdeniz, G., & Chawes, B. (2020). The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review. Metabolites, 10(12), . https://doi.org/10.3390/metabo10120511
Schjødt, Mette S, et al. "The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review." Metabolites vol. 10,12 (2020). doi: https://doi.org/10.3390/metabo10120511
Schjødt MS, Gürdeniz G, Chawes B. The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review. Metabolites. 2020 Dec 16;10(12). doi: 10.3390/metabo10120511. PMID: 33339279; PMCID: PMC7767195.
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Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin.

Frontiers in pharmacology

Aleidi SM, Dahabiyeh LA, Gu X, Al Dubayee M, Alshahrani A, Benabdelkamel H, Mujammami M, Li L, Aljada A, Abdel Rahman AM.
PMID: 33664666
Front Pharmacol. 2021 Feb 16;11:616157. doi: 10.3389/fphar.2020.616157. eCollection 2020.

Metformin is widely used in the treatment of Type 2 Diabetes Mellitus (T2DM). However, it is known to have beneficial effects in many other conditions, including obesity and cancer. In this study, we aimed to investigate the metabolic effect...

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Aleidi SM, Dahabiyeh LA, Gu X, et al. Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin. Front Pharmacol. 2021;11:616157doi: 10.3389/fphar.2020.616157.
Aleidi, S. M., Dahabiyeh, L. A., Gu, X., Al Dubayee, M., Alshahrani, A., Benabdelkamel, H., Mujammami, M., Li, L., Aljada, A., & Abdel Rahman, A. M. (2020). Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin. Frontiers in pharmacology, 11616157. https://doi.org/10.3389/fphar.2020.616157
Aleidi, Shereen M, et al. "Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin." Frontiers in pharmacology vol. 11 (2020): 616157. doi: https://doi.org/10.3389/fphar.2020.616157
Aleidi SM, Dahabiyeh LA, Gu X, Al Dubayee M, Alshahrani A, Benabdelkamel H, Mujammami M, Li L, Aljada A, Abdel Rahman AM. Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin. Front Pharmacol. 2021 Feb 16;11:616157. doi: 10.3389/fphar.2020.616157. eCollection 2020. PMID: 33664666; PMCID: PMC7921791.
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Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice.

Physiology & behavior

Zhang X, Yoshihara K, Miyata N, Hata T, Altaisaikhan A, Takakura S, Asano Y, Izuno S, Sudo N.
PMID: 34800493
Physiol Behav. 2021 Nov 18;244:113653. doi: 10.1016/j.physbeh.2021.113653. Epub 2021 Nov 18.

Important precursors of monoaminergic neurotransmitters, dietary tryptophan (TRP), tyrosine, and phenylalanine (all referred to as TTP), play crucial roles in a wide range of behavioral and emotional functions. In the current study, we investigated whether diets devoid of TTP...

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Zhang X, Yoshihara K, Miyata N, et al. Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice. Physiol Behav. 2021;244:113653doi: 10.1016/j.physbeh.2021.113653.
Zhang, X., Yoshihara, K., Miyata, N., Hata, T., Altaisaikhan, A., Takakura, S., Asano, Y., Izuno, S., & Sudo, N. (2021). Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice. Physiology & behavior, 244113653. https://doi.org/10.1016/j.physbeh.2021.113653
Zhang, Xueting, et al. "Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice." Physiology & behavior vol. 244 (2021): 113653. doi: https://doi.org/10.1016/j.physbeh.2021.113653
Zhang X, Yoshihara K, Miyata N, Hata T, Altaisaikhan A, Takakura S, Asano Y, Izuno S, Sudo N. Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice. Physiol Behav. 2021 Nov 18;244:113653. doi: 10.1016/j.physbeh.2021.113653. Epub 2021 Nov 18. PMID: 34800493.
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Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium.

International journal of geriatric psychiatry

Heylen A, Vermeiren Y, De Rooij SE, Scholtens RM, Van Munster BC, Van Dam D, De Deyn PP.
PMID: 34985774
Int J Geriatr Psychiatry. 2022 Feb;37(2). doi: 10.1002/gps.5677.

OBJECTIVES: Delirium frequently arises in older demented and non-demented patients in postoperative, clinical settings. To date, the underlying pathophysiological mechanisms remain poorly understood. Monoamine neurotransmitter alterations have been linked to delirium and cognitive impairment. Our aim was to investigate...

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Heylen A, Vermeiren Y, De Rooij SE, et al. Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. Int J Geriatr Psychiatry. 2022;37(2)doi: 10.1002/gps.5677.
Heylen, A., Vermeiren, Y., De Rooij, S. E., Scholtens, R. M., Van Munster, B. C., Van Dam, D., & De Deyn, P. P. (2022). Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. International journal of geriatric psychiatry, 37(2), . https://doi.org/10.1002/gps.5677
Heylen, Annelies, et al. "Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium." International journal of geriatric psychiatry vol. 37,2 (2022). doi: https://doi.org/10.1002/gps.5677
Heylen A, Vermeiren Y, De Rooij SE, Scholtens RM, Van Munster BC, Van Dam D, De Deyn PP. Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. Int J Geriatr Psychiatry. 2022 Feb;37(2). doi: 10.1002/gps.5677. PMID: 34985774.
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False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma.

Nuclear medicine and molecular imaging

Alruwaili AA, Alduraibi AK, Alzayed MF.
PMID: 33968277
Nucl Med Mol Imaging. 2021 Apr;55(2):100-102. doi: 10.1007/s13139-021-00682-x. Epub 2021 Jan 18.

A healthy 52-year-old man started to have few minutes spells of palpitation, tachycardia, hot flashes, and chest tightness. He had a lab work-up for carcinoid, including 5-hydroxyindoleacetic acid (5-HIAA), which was negative. Months later, his symptoms became worse which...

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Alruwaili AA, Alduraibi AK, Alzayed MF. False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma. Nucl Med Mol Imaging. 2021;55(2):100-102doi: 10.1007/s13139-021-00682-x.
Alruwaili, A. A., Alduraibi, A. K., & Alzayed, M. F. (2021). False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma. Nuclear medicine and molecular imaging, 55(2), 100-102. https://doi.org/10.1007/s13139-021-00682-x
Alruwaili, Ahmed Abdulrahman, et al. "False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma." Nuclear medicine and molecular imaging vol. 55,2 (2021): 100-102. doi: https://doi.org/10.1007/s13139-021-00682-x
Alruwaili AA, Alduraibi AK, Alzayed MF. False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma. Nucl Med Mol Imaging. 2021 Apr;55(2):100-102. doi: 10.1007/s13139-021-00682-x. Epub 2021 Jan 18. PMID: 33968277; PMCID: PMC8053631.
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Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease.

Journal of veterinary internal medicine

Reimann MJ, Fredholm M, Cremer SE, Christiansen LB, Meurs KM, Møller JE, Häggström J, Lykkesfeldt J, Olsen LH.
PMID: 34599615
J Vet Intern Med. 2021 Nov;35(6):2596-2606. doi: 10.1111/jvim.16277. Epub 2021 Oct 02.

BACKGROUND: The neurotransmitter serotonin (5-HT) affects valvular degeneration and dogs with myxomatous mitral valve disease (MMVD) exhibit alterations in 5-HT signaling. In Maltese dogs, 3 single nucleotide polymorphisms (SNPs) in the 5-HT transporter (SERT) gene are suggested to associate...

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Reimann MJ, Fredholm M, Cremer SE, et al. Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease. J Vet Intern Med. 2021;35(6):2596-2606doi: 10.1111/jvim.16277.
Reimann, M. J., Fredholm, M., Cremer, S. E., Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, J., & Olsen, L. H. (2021). Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease. Journal of veterinary internal medicine, 35(6), 2596-2606. https://doi.org/10.1111/jvim.16277
Reimann, Maria J, et al. "Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease." Journal of veterinary internal medicine vol. 35,6 (2021): 2596-2606. doi: https://doi.org/10.1111/jvim.16277
Reimann MJ, Fredholm M, Cremer SE, Christiansen LB, Meurs KM, Møller JE, Häggström J, Lykkesfeldt J, Olsen LH. Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease. J Vet Intern Med. 2021 Nov;35(6):2596-2606. doi: 10.1111/jvim.16277. Epub 2021 Oct 02. PMID: 34599615.
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Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter.

European journal of case reports in internal medicine

Fragkou PC, Papadopoulos IA, Papadopoulos A, Kontoveros EA, Kaltsas G, Vassilara F.
PMID: 33585343
Eur J Case Rep Intern Med. 2021 Jan 20;8(1):002216. doi: 10.12890/2021_002216. eCollection 2021.

Pancreatic neuroendocrine neoplasms (PanNENs) rarely secrete serotonin, which is the main cause of carcinoid syndrome. One of its unusual manifestations is carcinoid heart disease or Hedinger's syndrome which is seldom accompanied by cardiac arrhythmias. We report the case of...

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Fragkou PC, Papadopoulos IA, Papadopoulos A, et al. Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter. Eur J Case Rep Intern Med. 2021;8(1):002216doi: 10.12890/2021_002216.
Fragkou, P. C., Papadopoulos, I. A., Papadopoulos, A., Kontoveros, E. A., Kaltsas, G., & Vassilara, F. (2021). Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter. European journal of case reports in internal medicine, 8(1), 002216. https://doi.org/10.12890/2021_002216
Fragkou, Paraskevi C, et al. "Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter." European journal of case reports in internal medicine vol. 8,1 (2021): 002216. doi: https://doi.org/10.12890/2021_002216
Fragkou PC, Papadopoulos IA, Papadopoulos A, Kontoveros EA, Kaltsas G, Vassilara F. Rare Presentation of a Metastatic Pancreatic Neuroendocrine Neoplasm Presenting with Atrial Flutter. Eur J Case Rep Intern Med. 2021 Jan 20;8(1):002216. doi: 10.12890/2021_002216. eCollection 2021. PMID: 33585343; PMCID: PMC7875581.
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Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium.

International journal of geriatric psychiatry

Heylen A, Vermeiren Y, De Rooij SE, Scholtens RM, Van Munster BC, Van Dam D, De Deyn PP.
PMID: 34985774
Int J Geriatr Psychiatry. 2022 Feb;37(2). doi: 10.1002/gps.5677.

OBJECTIVES: Delirium frequently arises in older demented and non-demented patients in postoperative, clinical settings. To date, the underlying pathophysiological mechanisms remain poorly understood. Monoamine neurotransmitter alterations have been linked to delirium and cognitive impairment. Our aim was to investigate...

Cite
Heylen A, Vermeiren Y, De Rooij SE, et al. Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. Int J Geriatr Psychiatry. 2022;37(2)doi: 10.1002/gps.5677.
Heylen, A., Vermeiren, Y., De Rooij, S. E., Scholtens, R. M., Van Munster, B. C., Van Dam, D., & De Deyn, P. P. (2022). Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. International journal of geriatric psychiatry, 37(2), . https://doi.org/10.1002/gps.5677
Heylen, Annelies, et al. "Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium." International journal of geriatric psychiatry vol. 37,2 (2022). doi: https://doi.org/10.1002/gps.5677
Heylen A, Vermeiren Y, De Rooij SE, Scholtens RM, Van Munster BC, Van Dam D, De Deyn PP. Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium. Int J Geriatr Psychiatry. 2022 Feb;37(2). doi: 10.1002/gps.5677. PMID: 34985774.
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Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis.

Infection and drug resistance

Jiang J, Li Z, Chen C, Jiang W, Xu B, Zhao Q.
PMID: 34815677
Infect Drug Resist. 2021 Nov 15;14:4795-4807. doi: 10.2147/IDR.S330493. eCollection 2021.

PURPOSE: To investigate the dysregulated pathways and identify reliable diagnostic biomarkers for tuberculosis using integrated analysis of metabolomics and transcriptomics.METHODS: Three groups of samples, untargeted metabolomics analysis of healthy controls (HC), latent tuberculosis infection patients (LTBI), and active tuberculosis...

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Jiang J, Li Z, Chen C, et al. Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis. Infect Drug Resist. 2021;14:4795-4807doi: 10.2147/IDR.S330493.
Jiang, J., Li, Z., Chen, C., Jiang, W., Xu, B., & Zhao, Q. (2021). Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis. Infection and drug resistance, 144795-4807. https://doi.org/10.2147/IDR.S330493
Jiang, Jiayan, et al. "Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis." Infection and drug resistance vol. 14 (2021): 4795-4807. doi: https://doi.org/10.2147/IDR.S330493
Jiang J, Li Z, Chen C, Jiang W, Xu B, Zhao Q. Metabolomics Strategy Assisted by Transcriptomics Analysis to Identify Potential Biomarkers Associated with Tuberculosis. Infect Drug Resist. 2021 Nov 15;14:4795-4807. doi: 10.2147/IDR.S330493. eCollection 2021. PMID: 34815677; PMCID: PMC8604652.
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Showing 181 to 190 of 190 entries