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Showing 13 to 24 of 26 entries
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Double Negative (DN) B cells: A connecting bridge between rheumatic diseases and COVID-19?.

Mediterranean journal of rheumatology

Sachinidis A, Garyfallos A.
PMID: 34964023
Mediterr J Rheumatol. 2021 Sep 30;32(3):192-199. doi: 10.31138/mjr.32.3.192. eCollection 2021 Sep.

Double Negative (DN) B cells constitute a B cell population that lacks expression of immunoglobulin D and CD27 memory marker. These cells expand in elderly healthy individuals, but also accumulate prematurely in autoimmune and infectious diseases. COVID-19 is a...

Refractory IgD Multiple Myeloma Treated with Daratumumab: A Case Report and Literature Review.

Case reports in oncological medicine

Husnain M, Kurtin S, Barkett N, Riaz IB, Agarwal A.
PMID: 27752376
Case Rep Oncol Med. 2016;2016:2490168. doi: 10.1155/2016/2490168. Epub 2016 Sep 26.

Patients with relapsed and refractory multiple myeloma have poor prognosis. A recent analysis of patients with relapsed and refractory multiple myeloma who were refractory to both proteasome inhibitors and immunomodulatory drugs showed the median overall survival of 9 months...

Double Negative (DN) B cells: A connecting bridge between rheumatic diseases and COVID-19?.

Mediterranean journal of rheumatology

Sachinidis A, Garyfallos A.
PMID: 34964023
Mediterr J Rheumatol. 2021 Sep 30;32(3):192-199. doi: 10.31138/mjr.32.3.192. eCollection 2021 Sep.

Double Negative (DN) B cells constitute a B cell population that lacks expression of immunoglobulin D and CD27 memory marker. These cells expand in elderly healthy individuals, but also accumulate prematurely in autoimmune and infectious diseases. COVID-19 is a...

Spatio-temporal expression of blunt snout bream (Megalobrama amblycephala) mIgD and its immune response to Aeromonas hydrophila.

Central-European journal of immunology

Xia H, Wu K, Liu W, Wang W, Zhang X.
PMID: 26557025
Cent Eur J Immunol. 2015;40(2):132-41. doi: 10.5114/ceji.2015.52825. Epub 2015 Aug 03.

The function of IgD in fish and mammals has not been fully understood since its discovery. In this study, we have isolated and characterized the cDNA that encodes membrane-bound form of the immunoglobulin D heavy chain gene (mIgD) of...

An Extremely Rare Manifestation of Multiple Myeloma: An Immunoglobulin D Secreting Testicular Plasmacytoma.

Cureus

Sharma A, Binazir T, Sintow A, Lee CC, Shaharyar S, Tache J.
PMID: 28845377
Cureus. 2017 Jun 27;9(6):e1400. doi: 10.7759/cureus.1400.

Multiple myelomas (MM) of the immunoglobulin D (IgD) subtype is rare amongst plasma cell malignancies. It can present a diagnostic challenge because of the low amount of immunoglobulin in the serum. The amount of monoclonal (M)-protein is often undetectable...

Childhood and Adolescent nodular lymphocyte predominant Hodgkin lymphoma - A review of clinical outcome based on the histological variants.

British journal of haematology

Shankar AG, Kirkwood AA, Hall GW, Hayward J, O'Hare P, Ramsay AD.
PMID: 26115355
Br J Haematol. 2015 Oct;171(2):254-262. doi: 10.1111/bjh.13540. Epub 2015 Jun 26.

Nodular lymphocyte predominant Hodgkin lymphoma (nLPHL) comprises approximately 10-12% of all childhood Hodgkin lymphoma. As the majority have low stage disease recent years have seen a de-escalation of treatment intensity to avoid treatment-related morbidity. This report evaluates treatment outcome...

CP-25 Attenuates the Activation of CD4.

Frontiers in pharmacology

Wu YJ, Chen HS, Chen WS, Dong J, Dong XJ, Dai X, Huang Q, Wei W.
PMID: 29410624
Front Pharmacol. 2018 Jan 23;9:4. doi: 10.3389/fphar.2018.00004. eCollection 2018.

Researchers have shown that the level of immunoglobulin D (IgD) is often elevated in patients with autoimmune diseases. The possible roles of IgD on the function of human T cell activation are still unclear. Paeoniflorin-6'-

An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis.

Acta pharmacologica Sinica

Hu XX, Zhang AJ, Pan WW, Xin QL, Chen JY, Zhang LL, Chang Y, Wu YJ, Wei W.
PMID: 33864023
Acta Pharmacol Sin. 2021 Apr 16; doi: 10.1038/s41401-021-00665-w. Epub 2021 Apr 16.

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovitis and the destruction of small joints. Emerging evidence shows that immunoglobulin D (IgD) stimulation induces T-cell activation, which may contribute to diseases pathogenesis in RA. In this...

A research standard for human serum immunoglobulin D.

Bulletin of the World Health Organization

Rowe DS, Anderson SG, Tackett L.
PMID: 5313075
Bull World Health Organ. 1970;43(4):607-9.
Free PMC Article

No abstract available.

Four immunoglobulin isotypes and IgD splice variants in urodele amphibians.

Developmental and comparative immunology

Yoshinaga K, Oshio H, Prasetio B, Hayashida H, Maeda E, Matsumoto M.
PMID: 33301796
Dev Comp Immunol. 2021 Mar;116:103963. doi: 10.1016/j.dci.2020.103963. Epub 2020 Dec 07.

Until recently, different families of urodele amphibians were thought to express distinct subsets of immunoglobulin (Ig) isotypes. In this study, we explored cDNAs encoding Ig heavy-chains (H-chains) in three species of urodele amphibians. We found that Cynops pyrrhogaster, Pleurodeles...

[Immunoglobulin D multiple myeloma with elevated creatine kinase and numb chin syndrome: a case report].

Zhonghua zhong liu za zhi [Chinese journal of oncology]

Liu L, Dong WH, Du YH, Song XF, Yuan CL, Li Z.
PMID: 29151296
Zhonghua Zhong Liu Za Zhi. 2017 Nov 23;39(11):879-880. doi: 10.3760/cma.j.issn.0253-3766.2017.11.012.

No abstract available.

The therapeutic implications of activated immune responses via the enigmatic immunoglobulin D.

International reviews of immunology

Nguyen TG.
PMID: 33410368
Int Rev Immunol. 2021 Jan 07;1-24. doi: 10.1080/08830185.2020.1861265. Epub 2021 Jan 07.

Immunoglobulin D (IgD) is an enigmatic antibody and the least appreciated member of the immunoglobulin (Ig) family. Since its discovery over half a century ago, the essence of its function in the immune system has been somewhat enigmatic and...

Showing 13 to 24 of 26 entries