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Showing 133 to 134 of 134 entries
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Extracellular vesicles derived from macrophages display glycyl-tRNA synthetase 1 and exhibit anti-cancer activity.

Journal of extracellular vesicles

Goughnour PC, Park MC, Kim SB, Jun S, Yang WS, Chae S, Cho S, Song C, Lee JH, Hyun JK, Kim BG, Hwang D, Jung HS, Gho YS, Kim S.
PMID: 33708357
J Extracell Vesicles. 2020 Nov;10(1):e12029. doi: 10.1002/jev2.12029. Epub 2020 Dec 01.

Glycyl-tRNA synthetase 1 (GARS1), a cytosolic enzyme secreted from macrophages, promotes apoptosis in cancer cells. However, the mechanism underlying GARS1 secretion has not been elucidated. Here, we report that GARS1 is secreted through unique extracellular vesicles (EVs) with a...

Insulin-like growth factor 2-enhanced osteogenic differentiation of stem cell spheroids by regulation of Runx2 and Col1 expression.

Experimental and therapeutic medicine

Min SK, Kim M, Park JB.
PMID: 33680105
Exp Ther Med. 2021 Apr;21(4):383. doi: 10.3892/etm.2021.9814. Epub 2021 Feb 22.

Insulin-like growth factor 2 (IGF-2) is a growth factor that is involved in various functions of cells, including stem cells. The effects of IGF-2 on the cellular viability and osteogenic differentiation of stem cell spheroids were investigated in the...

Showing 133 to 134 of 134 entries