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Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases.

Clinical pharmacology : advances and applications

Dreesen E, Bossuyt P, Mulleman D, Gils A, Pascual-Salcedo D.
PMID: 29042821
Clin Pharmacol. 2017 Oct 03;9:101-111. doi: 10.2147/CPAA.S138414. eCollection 2017.

Biopharmaceuticals directed against tumor necrosis factor-alpha, integrins, interleukins, interferons and their receptors have become key agents for the management of inflammatory diseases in the fields of gastroenterology, rheumatology, dermatology and neurology. However, response to these treatments is far from...

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Dreesen E, Bossuyt P, Mulleman D, et al. Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases. Clin Pharmacol. 2017;9:101-111doi: 10.2147/CPAA.S138414.
Dreesen, E., Bossuyt, P., Mulleman, D., Gils, A., & Pascual-Salcedo, D. (2017). Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases. Clinical pharmacology : advances and applications, 9101-111. https://doi.org/10.2147/CPAA.S138414
Dreesen, Erwin, et al. "Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases." Clinical pharmacology : advances and applications vol. 9 (2017): 101-111. doi: https://doi.org/10.2147/CPAA.S138414
Dreesen E, Bossuyt P, Mulleman D, Gils A, Pascual-Salcedo D. Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases. Clin Pharmacol. 2017 Oct 03;9:101-111. doi: 10.2147/CPAA.S138414. eCollection 2017. PMID: 29042821; PMCID: PMC5633318.
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Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR.

Data in brief

Degryse B, Britto M, Shan CX, Wallace RG, Rochfort KD, Cummins PM, Meade G, Murphy RP.
PMID: 29085875
Data Brief. 2017 Oct 16;15:600-605. doi: 10.1016/j.dib.2017.10.023. eCollection 2017 Dec.

The data presented herein are connected to our research article (doi: 10.1016/j.biocel.2017.04.012) [1], in which we investigated the functional connections between the urokinase receptor (uPAR), and the ezrin/radixin/moesin (ERM) proteins, moesin and merlin [1]. Firstly, a model of action...

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Degryse B, Britto M, Shan CX, et al. Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR. Data Brief. 2017;15:600-605doi: 10.1016/j.dib.2017.10.023.
Degryse, B., Britto, M., Shan, C. X., Wallace, R. G., Rochfort, K. D., Cummins, P. M., Meade, G., & Murphy, R. P. (2017). Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR. Data in brief, 15600-605. https://doi.org/10.1016/j.dib.2017.10.023
Degryse, Bernard, et al. "Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR." Data in brief vol. 15 (2017): 600-605. doi: https://doi.org/10.1016/j.dib.2017.10.023
Degryse B, Britto M, Shan CX, Wallace RG, Rochfort KD, Cummins PM, Meade G, Murphy RP. Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR. Data Brief. 2017 Oct 16;15:600-605. doi: 10.1016/j.dib.2017.10.023. eCollection 2017 Dec. PMID: 29085875; PMCID: PMC5655590.
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Keep Eyes on Integrins.

Journal of immunobiology

Fan Z, Liu W.
PMID: 27054197
J Immunobiol. 2016 Feb;1(1). Epub 2016 Feb 27.

No abstract available.

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Fan Z, Liu W. Keep Eyes on Integrins. J Immunobiol. 2016;1(1)
Fan, Z., & Liu, W. (2016). Keep Eyes on Integrins. Journal of immunobiology, 1(1), .
Fan, Zhichao, and Liu, Wei. "Keep Eyes on Integrins." Journal of immunobiology vol. 1,1 (2016).
Fan Z, Liu W. Keep Eyes on Integrins. J Immunobiol. 2016 Feb;1(1). Epub 2016 Feb 27. PMID: 27054197; PMCID: PMC4819984.
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Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer.

International journal of clinical and experimental medicine

Cao Y, Zhou Y, Zhuang Q, Cui L, Xu X, Xu R, He X.
PMID: 26550128
Int J Clin Exp Med. 2015 Aug 15;8(8):12182-91. eCollection 2015.

In this study, we report an active targeting liposomal formulation directed by a novel peptide (RGD) that specifically binds to the integrins receptors overexpressed on prostatic cancer cells. The objectives of this study were to evaluate the in vitro...

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Cao Y, Zhou Y, Zhuang Q, et al. Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer. Int J Clin Exp Med. 2015;8(8):12182-91
Cao, Y., Zhou, Y., Zhuang, Q., Cui, L., Xu, X., Xu, R., & He, X. (2015). Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer. International journal of clinical and experimental medicine, 8(8), 12182-91.
Cao, Yunjie, et al. "Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer." International journal of clinical and experimental medicine vol. 8,8 (2015): 12182-91.
Cao Y, Zhou Y, Zhuang Q, Cui L, Xu X, Xu R, He X. Anti-tumor effect of RGD modified PTX loaded liposome on prostatic cancer. Int J Clin Exp Med. 2015 Aug 15;8(8):12182-91. eCollection 2015. PMID: 26550128; PMCID: PMC4612813.
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Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

Beilstein journal of organic chemistry

Bodero L, López Rivas P, Korsak B, Hechler T, Pahl A, Müller C, Arosio D, Pignataro L, Gennari C, Piarulli U.
PMID: 29520305
Beilstein J Org Chem. 2018 Feb 14;14:407-415. doi: 10.3762/bjoc.14.29. eCollection 2018.

RGD-α-amanitin and isoDGR-α-amanitin conjugates were synthesized by joining integrin ligands to α-amanitin via various linkers and spacers. The conjugates were evaluated for their ability to inhibit biotinylated vitronectin binding to the purified α

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Bodero L, López Rivas P, Korsak B, et al. Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting. Beilstein J Org Chem. 2018;14:407-415doi: 10.3762/bjoc.14.29.
Bodero, L., López Rivas, P., Korsak, B., Hechler, T., Pahl, A., Müller, C., Arosio, D., Pignataro, L., Gennari, C., & Piarulli, U. (2018). Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting. Beilstein journal of organic chemistry, 14407-415. https://doi.org/10.3762/bjoc.14.29
Bodero, Lizeth, et al. "Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting." Beilstein journal of organic chemistry vol. 14 (2018): 407-415. doi: https://doi.org/10.3762/bjoc.14.29
Bodero L, López Rivas P, Korsak B, Hechler T, Pahl A, Müller C, Arosio D, Pignataro L, Gennari C, Piarulli U. Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting. Beilstein J Org Chem. 2018 Feb 14;14:407-415. doi: 10.3762/bjoc.14.29. eCollection 2018. PMID: 29520305; PMCID: PMC5827777.
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Construction and Characterization of Recombinant HEK Cell Over Expressing α4 Integrin.

Advanced pharmaceutical bulletin

Naderi Beni S, Kouhpayeh S, Hejazi Z, Heidari Hafshejani N, Khanahmad H.
PMID: 26504766
Adv Pharm Bull. 2015 Sep;5(3):429-34. doi: 10.15171/apb.2015.058. Epub 2015 Sep 19.

PURPOSE: Integrins are heterodimeric membrane proteins, which are exposed to post translational modifications in eukaryotic cells in contrast to prokaryotic cells. These modifications provide advantages for production of proper nanobody, mono and polyclonal antibody against this surface protein and...

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Naderi Beni S, Kouhpayeh S, Hejazi Z, et al. Construction and Characterization of Recombinant HEK Cell Over Expressing α4 Integrin. Adv Pharm Bull. 2015;5(3):429-34doi: 10.15171/apb.2015.058.
Naderi Beni, S., Kouhpayeh, S., Hejazi, Z., Heidari Hafshejani, N., & Khanahmad, H. (2015). Construction and Characterization of Recombinant HEK Cell Over Expressing α4 Integrin. Advanced pharmaceutical bulletin, 5(3), 429-34. https://doi.org/10.15171/apb.2015.058
Naderi Beni, Shamsi, et al. "Construction and Characterization of Recombinant HEK Cell Over Expressing α4 Integrin." Advanced pharmaceutical bulletin vol. 5,3 (2015): 429-34. doi: https://doi.org/10.15171/apb.2015.058
Naderi Beni S, Kouhpayeh S, Hejazi Z, Heidari Hafshejani N, Khanahmad H. Construction and Characterization of Recombinant HEK Cell Over Expressing α4 Integrin. Adv Pharm Bull. 2015 Sep;5(3):429-34. doi: 10.15171/apb.2015.058. Epub 2015 Sep 19. PMID: 26504766; PMCID: PMC4616894.
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Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation.

Pharmacology research & perspectives

Porte J, Jenkins G.
PMID: 25505594
Pharmacol Res Perspect. 2014 Aug;2(4):e00030. doi: 10.1002/prp2.30. Epub 2014 Jun 09.

Transforming growth factor-β (TGF-β) plays an important role in the development of tissue fibrosis, and molecules inhibiting this pathway are attractive therapeutic targets for fibrotic diseases such as idiopathic pulmonary fibrosis (IPF). Activation of TGF-β is the rate-limiting step...

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Porte J, Jenkins G. Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation. Pharmacol Res Perspect. 2014;2(4):e00030doi: 10.1002/prp2.30.
Porte, J., & Jenkins, G. (2014). Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation. Pharmacology research & perspectives, 2(4), e00030. https://doi.org/10.1002/prp2.30
Porte, Joanne, and Jenkins, Gisli. "Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation." Pharmacology research & perspectives vol. 2,4 (2014): e00030. doi: https://doi.org/10.1002/prp2.30
Porte J, Jenkins G. Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation. Pharmacol Res Perspect. 2014 Aug;2(4):e00030. doi: 10.1002/prp2.30. Epub 2014 Jun 09. PMID: 25505594; PMCID: PMC4186436.
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Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma.

BMC clinical pathology

Denadai MV, Viana LS, Affonso RJ, Silva SR, Oliveira ID, Toledo SR, Matos D.
PMID: 23705994
BMC Clin Pathol. 2013 May 24;13:16. doi: 10.1186/1472-6890-13-16. eCollection 2013.

BACKGROUND: This study aimed to evaluate the relationship between the expression levels of selected integrin genes and proteins and cell differentiation, TNM stage, histological type and other variables potentially associated with the progression and dissemination of colorectal carcinoma (CRC).METHODS:...

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Denadai MV, Viana LS, Affonso RJ, et al. Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma. BMC Clin Pathol. 2013;13:16doi: 10.1186/1472-6890-13-16.
Denadai, M. V., Viana, L. S., Affonso, R. J., Silva, S. R., Oliveira, I. D., Toledo, S. R., & Matos, D. (2013). Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma. BMC clinical pathology, 1316. https://doi.org/10.1186/1472-6890-13-16
Denadai, Marcos Va, et al. "Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma." BMC clinical pathology vol. 13 (2013): 16. doi: https://doi.org/10.1186/1472-6890-13-16
Denadai MV, Viana LS, Affonso RJ, Silva SR, Oliveira ID, Toledo SR, Matos D. Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma. BMC Clin Pathol. 2013 May 24;13:16. doi: 10.1186/1472-6890-13-16. eCollection 2013. PMID: 23705994; PMCID: PMC3671190.
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Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes.

Proteome science

Fengos G, Schmidt A, Martin K, Fluri E, Aebersold R, Iber D, Pertz O.
PMID: 24987309
Proteome Sci. 2014 May 01;12:23. doi: 10.1186/1477-5956-12-23. eCollection 2014.

BACKGROUND: Tight spatio-temporal signaling of cytoskeletal and adhesion dynamics is required for localized membrane protrusion that drives directed cell migration. Different ensembles of proteins are therefore likely to get recruited and phosphorylated in membrane protrusions in response to specific...

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Fengos G, Schmidt A, Martin K, et al. Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes. Proteome Sci. 2014;12:23doi: 10.1186/1477-5956-12-23.
Fengos, G., Schmidt, A., Martin, K., Fluri, E., Aebersold, R., Iber, D., & Pertz, O. (2014). Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes. Proteome science, 1223. https://doi.org/10.1186/1477-5956-12-23
Fengos, Georgios, et al. "Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes." Proteome science vol. 12 (2014): 23. doi: https://doi.org/10.1186/1477-5956-12-23
Fengos G, Schmidt A, Martin K, Fluri E, Aebersold R, Iber D, Pertz O. Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes. Proteome Sci. 2014 May 01;12:23. doi: 10.1186/1477-5956-12-23. eCollection 2014. PMID: 24987309; PMCID: PMC4077045.
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Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials.

Biomaterials science

Feric N, Cheng CC, Goh MC, Dudnyk V, Di Tizio V, Radisic M.
PMID: 25485104
Biomater Sci. 2014 Oct 01;2(10):1384-1398. doi: 10.1039/C4BM00073K.

Bone loss occurs as a consequence of a variety of diseases as well as from traumatic injuries, and often requires therapeutic intervention. Strategies for repairing and replacing damaged and/or lost bone tissue include the use of biomaterials and medical...

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Feric N, Cheng CC, Goh MC, et al. Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials. Biomater Sci. 2014;2(10):1384-1398doi: 10.1039/C4BM00073K.
Feric, N., Cheng, C. C., Goh, M. C., Dudnyk, V., Di Tizio, V., & Radisic, M. (2014). Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials. Biomaterials science, 2(10), 1384-1398. https://doi.org/10.1039/C4BM00073K
Feric, Nicole, et al. "Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials." Biomaterials science vol. 2,10 (2014): 1384-1398. doi: https://doi.org/10.1039/C4BM00073K
Feric N, Cheng CC, Goh MC, Dudnyk V, Di Tizio V, Radisic M. Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials. Biomater Sci. 2014 Oct 01;2(10):1384-1398. doi: 10.1039/C4BM00073K. PMID: 25485104; PMCID: PMC4251595.
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Decreased stability of erythroblastic islands in integrin β3-deficient mice.

Physiological reports

Wang Z, Vogel O, Kuhn G, Gassmann M, Vogel J.
PMID: 24303107
Physiol Rep. 2013 Jul;1(2):e00018. doi: 10.1002/phy2.18. Epub 2013 Jun 28.

Erythroblasts proliferate and differentiate in hematopoietic organs within erythroblastic islands (EI) composed of erythropoietic progenitor cells attached to a central macrophage. This cellular interaction crucially involves the erythroid intercellular adhesion molecule-4 (ICAM-4) and αv integrin. Because integrins are biologically...

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Wang Z, Vogel O, Kuhn G, et al. Decreased stability of erythroblastic islands in integrin β3-deficient mice. Physiol Rep. 2013;1(2):e00018doi: 10.1002/phy2.18.
Wang, Z., Vogel, O., Kuhn, G., Gassmann, M., & Vogel, J. (2013). Decreased stability of erythroblastic islands in integrin β3-deficient mice. Physiological reports, 1(2), e00018. https://doi.org/10.1002/phy2.18
Wang, Zhenghui, et al. "Decreased stability of erythroblastic islands in integrin β3-deficient mice." Physiological reports vol. 1,2 (2013): e00018. doi: https://doi.org/10.1002/phy2.18
Wang Z, Vogel O, Kuhn G, Gassmann M, Vogel J. Decreased stability of erythroblastic islands in integrin β3-deficient mice. Physiol Rep. 2013 Jul;1(2):e00018. doi: 10.1002/phy2.18. Epub 2013 Jun 28. PMID: 24303107; PMCID: PMC3831914.
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Role of the β1 integrin molecule in T-cell activation and migration.

Modern rheumatology

Morimoto C, Kobayashi H, Nishijima R, Tanaka H, Iwata S.
PMID: 24383527
Mod Rheumatol. 2000 Mar;10(1):8-15. doi: 10.3109/s101650070032.

Abstract β1 integrins play crucial roles in a variety of cell processes such as adhesion, migration, proliferation, and differentiation of lymphocytes. To understand the molecular mechanisms of these various biological effects, it is particularly important to analyze cell signaling...

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Morimoto C, Kobayashi H, Nishijima R, et al. Role of the β1 integrin molecule in T-cell activation and migration. Mod Rheumatol. 2000;10(1):8-15doi: 10.3109/s101650070032.
Morimoto, C., Kobayashi, H., Nishijima, R., Tanaka, H., & Iwata, S. (2000). Role of the β1 integrin molecule in T-cell activation and migration. Modern rheumatology, 10(1), 8-15. https://doi.org/10.3109/s101650070032
Morimoto, C, et al. "Role of the β1 integrin molecule in T-cell activation and migration." Modern rheumatology vol. 10,1 (2000): 8-15. doi: https://doi.org/10.3109/s101650070032
Morimoto C, Kobayashi H, Nishijima R, Tanaka H, Iwata S. Role of the β1 integrin molecule in T-cell activation and migration. Mod Rheumatol. 2000 Mar;10(1):8-15. doi: 10.3109/s101650070032. PMID: 24383527.
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Showing 13 to 24 of 1370 entries