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Showing 25 to 36 of 848 entries
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Contemplating the Importance of Toll-like Receptors I and II Regarding Human Viral Pathogenesis.

Jundishapur journal of microbiology

Saeed U, Mazoor S, Jalal N, Zahid Piracha Z.
PMID: 25763131
Jundishapur J Microbiol. 2014 Dec 06;8(1):e13348. doi: 10.5812/jjm.13348. eCollection 2015 Jan.

BACKGROUND: Toll-like receptors (TLRs) play a major role in innate immunity, since they detect conserved pathogen-associated molecular patterns (PAMPs) on a range of microbes, including viruses, leading to innate immune activation and orchestration of the adaptive immune response.OBJECTIVES: The...

Current Options for the Therapy of Chronic Hepatitis B Infection.

Current infectious disease reports

Kioko Ono-Nita S, Kato N, Shiratori Y, Omata M.
PMID: 11286654
Curr Infect Dis Rep. 2001 Apr;3(2):137-142. doi: 10.1007/s11908-996-0036-2.

Until recently the only available treatment for chronic hepatitis B was interferon-alpha. Over the past few years a new class of antiviral has become available, the reverse transcriptase inhibitors. Lamivudine is a nucleoside analogue reverse transcriptase inhibitor that was...

Association of circulating CD8(+) lymphocytes to a spontaneous and interferon-alpha induced clearance of HCV.

Hepatology research : the official journal of the Japan Society of Hepatology

Bacosi M, De Angelis A, Ursitti A, Miglioresi L, Russo F, D'Innocenzo S, Ricci GL.
PMID: 12076711
Hepatol Res. 2002 Jul;23(3):163-166. doi: 10.1016/s1386-6346(01)00178-4.

The amount of copies of HCV-RNA and count of CD8(+) lymphocytes was retrospectively evaluated in 326 patients: sampling was performed in basal condition, during treatment with alpha-IFN (n=232) and post-treatment follow-up, and at the same time points in untreated...

Pharmacodynamic aspects of peptide administration biological response modifiers.

Advanced drug delivery reviews

Talmadge JE.
PMID: 10837664
Adv Drug Deliv Rev. 1998 Sep 07;33(3):241-252. doi: 10.1016/s0169-409x(98)00032-5.

Cytokines, growth factors and other recombinant proteins have been one of the most rapidly growing areas of pharmaceuticals. Further, the development of these bio-engineered drugs is occurring at an astonishing pace with rapid preclinical and clinical development and licensing...

[Autologous hematopoietic stem cell transplantation in chronic myeloid leukaemia with different clinical stages].

Magyar onkologia

Gopcsa L, Barta A, Bányai A, Földi J, Kalász L, Pajor L, Gidáli J, Pálóczi K.
PMID: 12050722
Magy Onkol. 2001;45(1):9-13. doi: HUON.2001.45.1.0009.

For most chronic myeloid leukaemia patients the option of a potentially curative allogeneic stem cell transplantation is not available because of age or lack of donor. Alternative therapy with interferon-alpha appears to prolong survival but is probably not curative....

Low complication rate during intraperitoneal therapy through a totally implanted peritoneal access port in patients with ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Nanninga AG, Willemse PH, Boonstra H, De Vries EG.
PMID: 11576244
Int J Gynecol Cancer. 1992 Mar;2(2):107-110. doi: 10.1046/j.1525-1438.1992.02020107.x.

Fifty-three patients with histologically proven ovarian cancer were treated with intraperitoneally administered cisplatin or human recombinant interferon-alpha through a totally implanted peritoneal access port. A total of 281 treatment courses were given. No complications related to surgical implantation of...

Clinical trials of immunotherapy for advanced prostate cancer.

Urologic oncology

Kuratsukuri K, Nishisaka N, Jones RF, Wang CY, Haas GP.
PMID: 11008095
Urol Oncol. 2000 Nov 01;5(6):265-273. doi: 10.1016/s1078-1439(00)00086-7.

There is a lack of effective therapeutic regimens for advanced hormone-refractory prostate cancer (HRPC). Recent combination regimens of chemotherapy have improved management of HRPC. Neither systemic chemotherapy nor radiation regimens have significantly improved survival. Conventional systemic cytokine therapy has...

Production of the Cytokines by Blood Leukocytes, Activated with Cycloferon.

Russian journal of immunology : RJI : official journal of Russian Society of Immunology

Mendelenko MM, Kravchenko JN, Agadjanyan KV, Kravchenko AI.
PMID: 12687236
Russ J Immunol. 2001 Dec;6(4):377-382.

Our investigation is an attempt to confirm the probability to use the cycloferon for the extracorporeal immunopharmacotherapy. For this aim the leukocytes, obtained from 5 ml of venous blood of 17 healthy individuals, were stimulated by different doses of...

Intracerebral Meningiomas.

Current treatment options in neurology

Chamberlain MC.
PMID: 15157407
Curr Treat Options Neurol. 2004 Jul;6(4):297-305. doi: 10.1007/s11940-004-0029-0.

Meningiomas are extra-axial brain tumors of middle to late adult life, and they have a female predominance. Overall, 90% of meningiomas are benign, 6% are atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have...

Cotreatment with interferon-alpha and -gamma reduces liver fibrosis in a rat model.

Hepatology research : the official journal of the Japan Society of Hepatology

Takahara T, Sugiyama K, Zhang LP, Ando O, Fujii M, Yata Y, Bo J, Xue F, Minemura M, Watanabe A.
PMID: 15036071
Hepatol Res. 2004 Mar;28(3):146-154. doi: 10.1016/j.hepres.2003.11.003.

Background/Aims: Interferon-alpha is used widely to treat viral hepatitis. Interferon-gamma modulates a system attacking infected cells and also has an anti-fibrotic effect. A treatment with interferon-alpha and -gamma has undergone trials in eliminating hepatitis C virus. We investigated effects...

[Head and neck hemangiomas: how and when to treat].

Shanghai kou qiang yi xue = Shanghai journal of stomatology

Zheng JW, Wang YA, Zhou GY, Zhu HG, Ye WM, Zhang ZY.
PMID: 17924011
Shanghai Kou Qiang Yi Xue. 2007 Aug;16(4):337-42.

Hemangiomas are common benign vascular tumors of infancy characterized by a proliferative growth phase followed by very slow inevitable regression (involutive phase) between one to ten years of age, about 60% to 70% of the lesions are found in...

Effect of induced pyometra on luteal lifespan and uterine fluid concentrations of prostaglandins and interferons in cows.

Theriogenology

Davidson JA, Wright DJ, Archbald LF, Klapstein E, Gottshall SL, Hansen PJ.
PMID: 16727809
Theriogenology. 1996 Jan 15;45(2):459-70. doi: 10.1016/0093-691x(95)00382-i.

The objective was to determine whether occurrence of persistent corpora lutea in cows with pyometra could be explained by accumulation of prostaglandins and interferons in the uterus. Pyometra was induced by treatment with hCG, followed by intrauterine infusions of...

Showing 25 to 36 of 848 entries