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Showing 385 to 386 of 386 entries
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Prophylactic Knockdown of the miR-183/96/182 Cluster Ameliorates Pseudomonas aeruginosa-Induced Keratitis.

Investigative ophthalmology & visual science

McClellan S, Pitchaikannu A, Wright R, Bessert D, Iulianelli M, Hazlett LD, Xu S.
PMID: 34919120
Invest Ophthalmol Vis Sci. 2021 Dec 01;62(15):14. doi: 10.1167/iovs.62.15.14.

PURPOSE: Previously, we demonstrated that miR-183/96/182 cluster (miR-183C) knockout mice exhibit decreased severity of Pseudomonas aeruginosa (PA)-induced keratitis. This study tests the hypothesis that prophylactic knockdown of miR-183C ameliorates PA keratitis indicative of a therapeutic potential.METHODS: Eight-week-old miR-183C wild-type...

In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography.

Investigative ophthalmology & visual science

Ghassabi Z, Kuranov RV, Schuman JS, Zambrano R, Wu M, Liu M, Tayebi B, Wang Y, Rubinoff I, Liu X, Wollstein G, Zhang HF, Ishikawa H.
PMID: 35024761
Invest Ophthalmol Vis Sci. 2022 Jan 03;63(1):18. doi: 10.1167/iovs.63.1.18.

PURPOSE: Growing evidence suggests that dendrite retraction or degeneration in a subpopulation of the retinal ganglion cells (RGCs) may precede detectable soma abnormalities and RGC death in glaucoma. Visualization of the lamellar structure of the inner plexiform layer (IPL)...

Showing 385 to 386 of 386 entries