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Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities.

Journal of diabetes and its complications

Khunti K, Heerspink HJL, Lam CSP, Nicolucci A, Ramirez L, Surmont F, Fenici P, Kosiborod M.
PMID: 34686406
J Diabetes Complications. 2021 Dec;35(12):108077. doi: 10.1016/j.jdiacomp.2021.108077. Epub 2021 Oct 13.

AIM: The DISCOVER Global Registry (DGR) aims to provide insights into patient attributes and treatment patterns in patients with type 2 diabetes mellitus (T2DM) seen in clinical practice and understand the patterns and impact of treatment strategies on cardio-renal-metabolic...

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Khunti K, Heerspink HJL, Lam CSP, et al. Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. J Diabetes Complications. 2021;35(12):108077doi: 10.1016/j.jdiacomp.2021.108077.
Khunti, K., Heerspink, H. J. L., Lam, C. S. P., Nicolucci, A., Ramirez, L., Surmont, F., Fenici, P., & Kosiborod, M. (2021). Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. Journal of diabetes and its complications, 35(12), 108077. https://doi.org/10.1016/j.jdiacomp.2021.108077
Khunti, Kamlesh, et al. "Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities." Journal of diabetes and its complications vol. 35,12 (2021): 108077. doi: https://doi.org/10.1016/j.jdiacomp.2021.108077
Khunti K, Heerspink HJL, Lam CSP, Nicolucci A, Ramirez L, Surmont F, Fenici P, Kosiborod M. Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. J Diabetes Complications. 2021 Dec;35(12):108077. doi: 10.1016/j.jdiacomp.2021.108077. Epub 2021 Oct 13. PMID: 34686406.
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Emotional burden and care of adults with type 1 diabetes during the COVID-19 pandemic in Brazilian regions.

Journal of diabetes and its complications

Silveira MSVM, Pavin EJ, Cardoso EB, Fanti P, Abdoli S.
PMID: 34620557
J Diabetes Complications. 2021 Dec;35(12):108053. doi: 10.1016/j.jdiacomp.2021.108053. Epub 2021 Sep 28.

AIMS: This study investigated the emotional burden in persons with type 1 diabetes (PWT1D) during the COVID-19 pandemic in Brazilian regions and evaluated which COVID-19, sociodemographic/clinical characteristics are related to it.METHODS: In a cross-sectional study, T1D adults completed a...

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Silveira MSVM, Pavin EJ, Cardoso EB, et al. Emotional burden and care of adults with type 1 diabetes during the COVID-19 pandemic in Brazilian regions. J Diabetes Complications. 2021;35(12):108053doi: 10.1016/j.jdiacomp.2021.108053.
Silveira, M. S. V. M., Pavin, E. J., Cardoso, E. B., Fanti, P., & Abdoli, S. (2021). Emotional burden and care of adults with type 1 diabetes during the COVID-19 pandemic in Brazilian regions. Journal of diabetes and its complications, 35(12), 108053. https://doi.org/10.1016/j.jdiacomp.2021.108053
Silveira, Mônica S V M, et al. "Emotional burden and care of adults with type 1 diabetes during the COVID-19 pandemic in Brazilian regions." Journal of diabetes and its complications vol. 35,12 (2021): 108053. doi: https://doi.org/10.1016/j.jdiacomp.2021.108053
Silveira MSVM, Pavin EJ, Cardoso EB, Fanti P, Abdoli S. Emotional burden and care of adults with type 1 diabetes during the COVID-19 pandemic in Brazilian regions. J Diabetes Complications. 2021 Dec;35(12):108053. doi: 10.1016/j.jdiacomp.2021.108053. Epub 2021 Sep 28. PMID: 34620557; PMCID: PMC8597042.
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Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice.

Journal of diabetes and its complications

Casimiro I, Stull ND, Tersey SA, Mirmira RG.
PMID: 33308894
J Diabetes Complications. 2021 Feb;35(2):107795. doi: 10.1016/j.jdiacomp.2020.107795. Epub 2020 Nov 28.

BACKGROUND: Obesity and the metabolic syndrome are increasingly prevalent in society and their complications and response to treatment exhibit sexual dimorphism. Mouse models of high fat diet-induced obesity are commonly used for both mechanistic and therapeutic studies of metabolic...

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Casimiro I, Stull ND, Tersey SA, et al. Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice. J Diabetes Complications. 2020;35(2):107795doi: 10.1016/j.jdiacomp.2020.107795.
Casimiro, I., Stull, N. D., Tersey, S. A., & Mirmira, R. G. (2021). Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice. Journal of diabetes and its complications, 35(2), 107795. https://doi.org/10.1016/j.jdiacomp.2020.107795
Casimiro, Isabel, et al. "Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice." Journal of diabetes and its complications vol. 35,2 (2021): 107795. doi: https://doi.org/10.1016/j.jdiacomp.2020.107795
Casimiro I, Stull ND, Tersey SA, Mirmira RG. Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice. J Diabetes Complications. 2021 Feb;35(2):107795. doi: 10.1016/j.jdiacomp.2020.107795. Epub 2020 Nov 28. PMID: 33308894; PMCID: PMC7856196.
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Risk factors associated with postpartum impaired glucose regulation in women with previous gestational diabetes.

Journal of diabetes and its complications

Bianchi C, de Gennaro G, Brocchi A, Minaldi E, Del Prato S, Bertolotto A.
PMID: 33468397
J Diabetes Complications. 2021 Apr;35(4):107854. doi: 10.1016/j.jdiacomp.2021.107854. Epub 2021 Jan 09.

AIMS: For women with previous gestational diabetes (GDM), international guidelines recommend 75 g oral glucose tolerance test (OGTT) at 4-12 weeks after delivery to assess glucose tolerance, considering their increased risk of type 2 diabetes. We evaluated prevalence of...

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Bianchi C, de Gennaro G, Brocchi A, et al. Risk factors associated with postpartum impaired glucose regulation in women with previous gestational diabetes. J Diabetes Complications. 2021;35(4):107854doi: 10.1016/j.jdiacomp.2021.107854.
Bianchi, C., de Gennaro, G., Brocchi, A., Minaldi, E., Del Prato, S., & Bertolotto, A. (2021). Risk factors associated with postpartum impaired glucose regulation in women with previous gestational diabetes. Journal of diabetes and its complications, 35(4), 107854. https://doi.org/10.1016/j.jdiacomp.2021.107854
Bianchi, Cristina, et al. "Risk factors associated with postpartum impaired glucose regulation in women with previous gestational diabetes." Journal of diabetes and its complications vol. 35,4 (2021): 107854. doi: https://doi.org/10.1016/j.jdiacomp.2021.107854
Bianchi C, de Gennaro G, Brocchi A, Minaldi E, Del Prato S, Bertolotto A. Risk factors associated with postpartum impaired glucose regulation in women with previous gestational diabetes. J Diabetes Complications. 2021 Apr;35(4):107854. doi: 10.1016/j.jdiacomp.2021.107854. Epub 2021 Jan 09. PMID: 33468397.
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The co-existence of diabetes and subclinical atherosclerosis in rural central Appalachia: Do residential characteristics matter?.

Journal of diabetes and its complications

Mamudu HM, Jones A, Paul TK, Osedeme F, Stewart D, Alamian A, Wang L, Orimaye S, Bledsoe J, Poole A, Blackwell G, Budoff M.
PMID: 33468398
J Diabetes Complications. 2021 Apr;35(4):107851. doi: 10.1016/j.jdiacomp.2021.107851. Epub 2021 Jan 09.

Aim Disparities exist in cardiovascular diseases (CVD) and diabetes in the United States (U.S.) with Central Appalachia having disproportionate burden. This study examined prevalence and correlates of CVD risk-factors among patients with diabetes/subclinical atherosclerosis in Central Appalachia.METHODS: During 2012-2016,...

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Mamudu HM, Jones A, Paul TK, et al. The co-existence of diabetes and subclinical atherosclerosis in rural central Appalachia: Do residential characteristics matter?. J Diabetes Complications. 2021;35(4):107851doi: 10.1016/j.jdiacomp.2021.107851.
Mamudu, H. M., Jones, A., Paul, T. K., Osedeme, F., Stewart, D., Alamian, A., Wang, L., Orimaye, S., Bledsoe, J., Poole, A., Blackwell, G., & Budoff, M. (2021). The co-existence of diabetes and subclinical atherosclerosis in rural central Appalachia: Do residential characteristics matter?. Journal of diabetes and its complications, 35(4), 107851. https://doi.org/10.1016/j.jdiacomp.2021.107851
Mamudu, Hadii M, et al. "The co-existence of diabetes and subclinical atherosclerosis in rural central Appalachia: Do residential characteristics matter?." Journal of diabetes and its complications vol. 35,4 (2021): 107851. doi: https://doi.org/10.1016/j.jdiacomp.2021.107851
Mamudu HM, Jones A, Paul TK, Osedeme F, Stewart D, Alamian A, Wang L, Orimaye S, Bledsoe J, Poole A, Blackwell G, Budoff M. The co-existence of diabetes and subclinical atherosclerosis in rural central Appalachia: Do residential characteristics matter?. J Diabetes Complications. 2021 Apr;35(4):107851. doi: 10.1016/j.jdiacomp.2021.107851. Epub 2021 Jan 09. PMID: 33468398.
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Glucose control, diabetic retinopathy, and hemodialysis induction in subjects with normo-microalbuminuric type 2 diabetic patients with normal renal function followed for 15 years.

Journal of diabetes and its complications

Moriya T, Hayashi A, Matsubara M, Suzuki A, Ouchi M.
PMID: 34740544
J Diabetes Complications. 2021 Oct 29;108080. doi: 10.1016/j.jdiacomp.2021.108080. Epub 2021 Oct 29.

AIMS: A high urinary albumin excretion (UAE) and low glomerular filtration rate (GFR) are risk factors for progressive renal function loss in type 2 diabetic patients. In addition, diabetic retinopathy (DR) is also a risk factor for progressive renal...

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Moriya T, Hayashi A, Matsubara M, et al. Glucose control, diabetic retinopathy, and hemodialysis induction in subjects with normo-microalbuminuric type 2 diabetic patients with normal renal function followed for 15 years. J Diabetes Complications. 2021;108080doi: 10.1016/j.jdiacomp.2021.108080.
Moriya, T., Hayashi, A., Matsubara, M., Suzuki, A., & Ouchi, M. (2021). Glucose control, diabetic retinopathy, and hemodialysis induction in subjects with normo-microalbuminuric type 2 diabetic patients with normal renal function followed for 15 years. Journal of diabetes and its complications, 108080. https://doi.org/10.1016/j.jdiacomp.2021.108080
Moriya, Tatsumi, et al. "Glucose control, diabetic retinopathy, and hemodialysis induction in subjects with normo-microalbuminuric type 2 diabetic patients with normal renal function followed for 15 years." Journal of diabetes and its complications vol. (2021): 108080. doi: https://doi.org/10.1016/j.jdiacomp.2021.108080
Moriya T, Hayashi A, Matsubara M, Suzuki A, Ouchi M. Glucose control, diabetic retinopathy, and hemodialysis induction in subjects with normo-microalbuminuric type 2 diabetic patients with normal renal function followed for 15 years. J Diabetes Complications. 2021 Oct 29;108080. doi: 10.1016/j.jdiacomp.2021.108080. Epub 2021 Oct 29. PMID: 34740544.
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Arteriolar hyalinosis is related to rapid GFR decline and long-standing GFR changes observed on renal biopsies in normo-microalbuminuric type 2 diabetic patients.

Journal of diabetes and its complications

Moriya T, Yamagishi T, Yoshida Y, Matsubara M, Ouchi M.
PMID: 33468395
J Diabetes Complications. 2021 Apr;35(4):107847. doi: 10.1016/j.jdiacomp.2021.107847. Epub 2021 Jan 07.

AIMS: Whether or not renal structural changes, especially arteriolar hyalinosis, are related to the rate of renal functional decline and increase in urinary albumin excretion (UAE) at the early stage of diabetic nephropathy in patients with type 2 diabetes...

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Moriya T, Yamagishi T, Yoshida Y, et al. Arteriolar hyalinosis is related to rapid GFR decline and long-standing GFR changes observed on renal biopsies in normo-microalbuminuric type 2 diabetic patients. J Diabetes Complications. 2021;35(4):107847doi: 10.1016/j.jdiacomp.2021.107847.
Moriya, T., Yamagishi, T., Yoshida, Y., Matsubara, M., & Ouchi, M. (2021). Arteriolar hyalinosis is related to rapid GFR decline and long-standing GFR changes observed on renal biopsies in normo-microalbuminuric type 2 diabetic patients. Journal of diabetes and its complications, 35(4), 107847. https://doi.org/10.1016/j.jdiacomp.2021.107847
Moriya, Tatsumi, et al. "Arteriolar hyalinosis is related to rapid GFR decline and long-standing GFR changes observed on renal biopsies in normo-microalbuminuric type 2 diabetic patients." Journal of diabetes and its complications vol. 35,4 (2021): 107847. doi: https://doi.org/10.1016/j.jdiacomp.2021.107847
Moriya T, Yamagishi T, Yoshida Y, Matsubara M, Ouchi M. Arteriolar hyalinosis is related to rapid GFR decline and long-standing GFR changes observed on renal biopsies in normo-microalbuminuric type 2 diabetic patients. J Diabetes Complications. 2021 Apr;35(4):107847. doi: 10.1016/j.jdiacomp.2021.107847. Epub 2021 Jan 07. PMID: 33468395.
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Insulin resistance-associated genetic variants in type 1 diabetes.

Journal of diabetes and its complications

Miller RG, McGurnaghan SJ, Onengut-Gumuscu S, Chen WM, Colhoun HM, Rich SS, Orchard TJ, Costacou T.
PMID: 33468396
J Diabetes Complications. 2021 Apr;35(4):107842. doi: 10.1016/j.jdiacomp.2020.107842. Epub 2021 Jan 09.

AIMS: To examine candidate insulin resistance single nucleotide polymorphisms (SNPs) for associations with glycemic control, insulin resistance, BMI, and complications in an observational type 1 diabetes (T1D) cohort: the Pittsburgh Epidemiology of Diabetes Complications (EDC) study.METHODS: In 422 European-ancestry...

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Miller RG, McGurnaghan SJ, Onengut-Gumuscu S, et al. Insulin resistance-associated genetic variants in type 1 diabetes. J Diabetes Complications. 2021;35(4):107842doi: 10.1016/j.jdiacomp.2020.107842.
Miller, R. G., McGurnaghan, S. J., Onengut-Gumuscu, S., Chen, W. M., Colhoun, H. M., Rich, S. S., Orchard, T. J., & Costacou, T. (2021). Insulin resistance-associated genetic variants in type 1 diabetes. Journal of diabetes and its complications, 35(4), 107842. https://doi.org/10.1016/j.jdiacomp.2020.107842
Miller, Rachel G, et al. "Insulin resistance-associated genetic variants in type 1 diabetes." Journal of diabetes and its complications vol. 35,4 (2021): 107842. doi: https://doi.org/10.1016/j.jdiacomp.2020.107842
Miller RG, McGurnaghan SJ, Onengut-Gumuscu S, Chen WM, Colhoun HM, Rich SS, Orchard TJ, Costacou T. Insulin resistance-associated genetic variants in type 1 diabetes. J Diabetes Complications. 2021 Apr;35(4):107842. doi: 10.1016/j.jdiacomp.2020.107842. Epub 2021 Jan 09. PMID: 33468396; PMCID: PMC7936951.
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Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities.

Journal of diabetes and its complications

Khunti K, Heerspink HJL, Lam CSP, Nicolucci A, Ramirez L, Surmont F, Fenici P, Kosiborod M.
PMID: 34686406
J Diabetes Complications. 2021 Dec;35(12):108077. doi: 10.1016/j.jdiacomp.2021.108077. Epub 2021 Oct 13.

AIM: The DISCOVER Global Registry (DGR) aims to provide insights into patient attributes and treatment patterns in patients with type 2 diabetes mellitus (T2DM) seen in clinical practice and understand the patterns and impact of treatment strategies on cardio-renal-metabolic...

Cite
Khunti K, Heerspink HJL, Lam CSP, et al. Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. J Diabetes Complications. 2021;35(12):108077doi: 10.1016/j.jdiacomp.2021.108077.
Khunti, K., Heerspink, H. J. L., Lam, C. S. P., Nicolucci, A., Ramirez, L., Surmont, F., Fenici, P., & Kosiborod, M. (2021). Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. Journal of diabetes and its complications, 35(12), 108077. https://doi.org/10.1016/j.jdiacomp.2021.108077
Khunti, Kamlesh, et al. "Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities." Journal of diabetes and its complications vol. 35,12 (2021): 108077. doi: https://doi.org/10.1016/j.jdiacomp.2021.108077
Khunti K, Heerspink HJL, Lam CSP, Nicolucci A, Ramirez L, Surmont F, Fenici P, Kosiborod M. Design and rationale of DISCOVER global registry in type 2 diabetes: Real-world insights of treatment patterns and its relationship with cardiovascular, renal, and metabolic multimorbidities. J Diabetes Complications. 2021 Dec;35(12):108077. doi: 10.1016/j.jdiacomp.2021.108077. Epub 2021 Oct 13. PMID: 34686406.
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Glycated albumin as biomarker: Evidence and its outcomes.

Journal of diabetes and its complications

Kohzuma T, Tao X, Koga M.
PMID: 34507877
J Diabetes Complications. 2021 Nov;35(11):108040. doi: 10.1016/j.jdiacomp.2021.108040. Epub 2021 Aug 30.

Glycemic control markers are important for the diagnosis and treatment of diabetes. Hemoglobin A1c (A1C) is an important marker that is mandatory in routine medical examinations; however, it is well known that it has some limitations. In this review,...

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Kohzuma T, Tao X, Koga M. Glycated albumin as biomarker: Evidence and its outcomes. J Diabetes Complications. 2021;35(11):108040doi: 10.1016/j.jdiacomp.2021.108040.
Kohzuma, T., Tao, X., & Koga, M. (2021). Glycated albumin as biomarker: Evidence and its outcomes. Journal of diabetes and its complications, 35(11), 108040. https://doi.org/10.1016/j.jdiacomp.2021.108040
Kohzuma, Takuji, et al. "Glycated albumin as biomarker: Evidence and its outcomes." Journal of diabetes and its complications vol. 35,11 (2021): 108040. doi: https://doi.org/10.1016/j.jdiacomp.2021.108040
Kohzuma T, Tao X, Koga M. Glycated albumin as biomarker: Evidence and its outcomes. J Diabetes Complications. 2021 Nov;35(11):108040. doi: 10.1016/j.jdiacomp.2021.108040. Epub 2021 Aug 30. PMID: 34507877.
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Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States.

Journal of diabetes and its complications

Eckert AJ, Zhou FL, Grimsmann JM, Pettus JH, Kerner W, Miller KM, Stechemesser L, Edelman SV, Spies C, Holl RW, Ibald-Mulli AM.
PMID: 33280985
J Diabetes Complications. 2021 Mar;35(3):107812. doi: 10.1016/j.jdiacomp.2020.107812. Epub 2020 Nov 26.

BACKGROUND: Studies on acute complications in adult T1D were previously reported from the United States (U.S.) and from Germany. The aim was to compare demographic characteristics and patterns of severe hypoglycaemia (SH) and diabetic ketoacidosis (DKA) between Germany and...

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Eckert AJ, Zhou FL, Grimsmann JM, et al. Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States. J Diabetes Complications. 2020;35(3):107812doi: 10.1016/j.jdiacomp.2020.107812.
Eckert, A. J., Zhou, F. L., Grimsmann, J. M., Pettus, J. H., Kerner, W., Miller, K. M., Stechemesser, L., Edelman, S. V., Spies, C., Holl, R. W., & Ibald-Mulli, A. M. (2021). Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States. Journal of diabetes and its complications, 35(3), 107812. https://doi.org/10.1016/j.jdiacomp.2020.107812
Eckert, Alexander J, et al. "Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States." Journal of diabetes and its complications vol. 35,3 (2021): 107812. doi: https://doi.org/10.1016/j.jdiacomp.2020.107812
Eckert AJ, Zhou FL, Grimsmann JM, Pettus JH, Kerner W, Miller KM, Stechemesser L, Edelman SV, Spies C, Holl RW, Ibald-Mulli AM. Demographic characteristics and acute complications among adults with type 1 diabetes: Comparison of two multicentre databases from Germany and the United States. J Diabetes Complications. 2021 Mar;35(3):107812. doi: 10.1016/j.jdiacomp.2020.107812. Epub 2020 Nov 26. PMID: 33280985.
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Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort.

Journal of diabetes and its complications

Harms PP, van der Heijden AA, Rutters F, Tan HL, Beulens JWJ, Nijpels G, Elders P.
PMID: 33280986
J Diabetes Complications. 2021 Feb;35(2):107810. doi: 10.1016/j.jdiacomp.2020.107810. Epub 2020 Nov 26.

AIMS: The American Diabetes Association, and the joint European Society of Cardiology and European Association for the Study of Diabetes guidelines recommend a resting ECG in people with type 2 diabetes with hypertension or suspected cardiovascular disease (CVD). However,...

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Harms PP, van der Heijden AA, Rutters F, et al. Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort. J Diabetes Complications. 2020;35(2):107810doi: 10.1016/j.jdiacomp.2020.107810.
Harms, P. P., van der Heijden, A. A., Rutters, F., Tan, H. L., Beulens, J. W. J., Nijpels, G., Elders, P. (2021). Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort. Journal of diabetes and its complications, 35(2), 107810. https://doi.org/10.1016/j.jdiacomp.2020.107810
Harms, Peter P, et al. "Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort." Journal of diabetes and its complications vol. 35,2 (2021): 107810. doi: https://doi.org/10.1016/j.jdiacomp.2020.107810
Harms PP, van der Heijden AA, Rutters F, Tan HL, Beulens JWJ, Nijpels G, Elders P. Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort. J Diabetes Complications. 2021 Feb;35(2):107810. doi: 10.1016/j.jdiacomp.2020.107810. Epub 2020 Nov 26. PMID: 33280986.
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