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Showing 25 to 36 of 64 entries
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Altered human alveolar bone gene expression in type 2 diabetes-A cross-sectional study.

Journal of periodontal research

Ayilavarapu S, Doctor A, Lee CT, Tribble GD, Chiu Y, Weltman RL, Angelov N.
PMID: 34783015
J Periodontal Res. 2022 Jan;57(1):142-151. doi: 10.1111/jre.12947. Epub 2021 Nov 15.

OBJECTIVE: The objective of this cross-sectional study is to investigate alveolar bone gene expression in health and diabetes through ribonucleic acid (RNA) sequencing and bioinformatics analysis.BACKGROUND: It is relatively unknown how type 2 diabetes modulates gene expression in alveolar...

Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies.

Journal of periodontal research

Baima G, Iaderosa G, Corana M, Romano F, Citterio F, Giacomino A, Berta GN, Aimetti M.
PMID: 34837226
J Periodontal Res. 2021 Nov 27; doi: 10.1111/jre.12956. Epub 2021 Nov 27.

OBJECTIVES: The present systematic review examined the available evidence on distinctive salivary ion profile in periodontitis compared to periodontal health and provided a qualitative assessment of the literature.BACKGROUND: Macro and trace elements are essential for cellular physiology, and their...

Functional Adaptation of LPS-affected Dentoalveolar Fibrous Joints in Rats.

Journal of periodontal research

Wang B, Ustriyana P, Tam CS, Lin JD, Srirangapatanam S, Kapila Y, Ryder MI, Webb S, Seo Y, Ho SP.
PMID: 34839547
J Periodontal Res. 2022 Jan;57(1):131-141. doi: 10.1111/jre.12946. Epub 2021 Nov 28.

INTRODUCTION: The functional interplay between cementum of the root and alveolar bone of the socket is tuned by a uniquely positioned 70-80 µm wide fibrous and lubricious ligament in a dentoalveolar joint (DAJ). In this study, structural and biomechanical...

Adjunctive Er:YAG laser in non-surgical periodontal therapy of patients with inadequately controlled type 2 diabetes mellitus: A split-mouth randomized controlled study.

Journal of periodontal research

Feng C, Ding Y, Tang L, Gui Y, Shen X, He L, Lu X, Leung WK.
PMID: 34610151
J Periodontal Res. 2022 Jan;57(1):63-74. doi: 10.1111/jre.12938. Epub 2021 Oct 05.

BACKGROUND AND OBJECTIVE: Limited studies are available comparing the outcomes of non-surgical periodontal therapy (NSPT) with or without adjunctive Er:YAG laser (ERL) in patients with type 2 diabetes mellitus (T2DM). This study evaluated the effects of ERL adjunctive NSPT...

Is TIMP-1 a biomarker for periodontal disease? A systematic review and meta-analysis.

Journal of periodontal research

de Brouwer P, Bikker FJ, Brand HS, Kaman WE.
PMID: 34850390
J Periodontal Res. 2021 Dec 01; doi: 10.1111/jre.12957. Epub 2021 Dec 01.

OBJECTIVE: One of the most important families of proteases associated with periodontal disease is the family of the matrix metalloproteinases (MMPs). Their activity is regulated by tissue inhibitors of metalloproteinases (TIMPs), and an imbalance between MMP activity and regulation...

Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.

Journal of periodontal research

Shimizu Y, Takeda-Kawaguchi T, Kuroda I, Hotta Y, Kawasaki H, Hariyama T, Shibata T, Akao Y, Kunisada T, Tatsumi J, Tezuka KI.
PMID: 34826339
J Periodontal Res. 2021 Nov 26; doi: 10.1111/jre.12949. Epub 2021 Nov 26.

BACKGROUND AND OBJECTIVE: Exosomes are small vesicles secreted from many cell types. Their biological effects largely depend on their cellular origin and the physiological state of the originating cells. Exosomes secreted by mesenchymal stem cells exert therapeutic effects against...

Differential regulation of NPY and SP receptor expression in STRO-1+ve PDLSCs by inflammatory cytokines.

Journal of periodontal research

Winning L, El Karim IA, Linden GJ, Irwin CR, Killough SA, Lundy FT.
PMID: 34773642
J Periodontal Res. 2021 Nov 13; doi: 10.1111/jre.12952. Epub 2021 Nov 13.

OBJECTIVES: The aims of this study were to investigate neuropeptide receptor expression regulation on STRO-1 +ve periodontal ligament stem cells (PDLSCs) in response to inflammatory cytokines and to investigate a potential osteogenic effect of neuropeptides.BACKGROUND: Nerve fibres innervating the...

Plasminogen gene polymorphisms [c.924C>T and IVS 8+14 G>A] in periodontitis and familial Mediterranean fever: A case-control study.

Journal of periodontal research

Fentoğlu Ö, Tülüceoğlu EE, Orhan H.
PMID: 34939186
J Periodontal Res. 2021 Dec 22; doi: 10.1111/jre.12966. Epub 2021 Dec 22.

BACKGROUND AND OBJECTIVE: The plasminogen (PLG) activation system plays an essential role in severe inflammation based diseases such as periodontitis, destructive membranous periodontal disease (ligneous periodontitis), familial Mediterranean fever (FMF), and amyloidosis. We have aimed to evaluate variations in...

Association of different antidepressant classes with clinical attachment level and alveolar bone loss in patients with periodontitis: A retrospective study.

Journal of periodontal research

Hakam AE, Duarte PM, Mbadu MP, Aukhil I, da Silva HDP, Chang J.
PMID: 34622954
J Periodontal Res. 2021 Oct 08; doi: 10.1111/jre.12939. Epub 2021 Oct 08.

OBJECTIVE: Our study aimed to determine the relationship of antidepressant medicine use with periodontal diseases, exploring the association of different pharmacological classes of antidepressant with observations of clinical attachment loss (CAL) and alveolar bone level (BL) in patients with...

In vitro evaluation of the effect of the electronic cigarette aerosol, Cannabis smoke, and conventional cigarette smoke on the properties of gingival fibroblasts/gingival mesenchymal stem cells.

Journal of periodontal research

El-Mouelhy ATM, Nasry SA, Abou El-Dahab O, Sabry D, Fawzy El-Sayed K.
PMID: 34748642
J Periodontal Res. 2022 Jan;57(1):104-114. doi: 10.1111/jre.12943. Epub 2021 Nov 08.

OBJECTIVE: The current study aimed to evaluate the effect of electronic cigarette (EC) aerosol, Cannabis, and conventional cigarettes smoke on gingival fibroblast/gingival mesenchymal stem cells' (GF/G-MSCs) of never smokers.MATERIAL AND METHODS: Human GF/G-MSCs (n = 32) were isolated and...

Surfactin reduces particulate matter-induced VCAM-1-dependent monocyte adhesion in human gingival fibroblasts by increasing Nrf2-dependent HO-1 expression.

Journal of periodontal research

Vo TTT, Huang HW, Wee Y, Feng SW, Cheng HC, Tuan VP, Lee IT.
PMID: 34716926
J Periodontal Res. 2022 Jan;57(1):115-130. doi: 10.1111/jre.12944. Epub 2021 Oct 30.

BACKGROUND AND OBJECTIVES: The mechanisms of particulate matter (PM) toxicity involve the generation of ROS and upregulation of proinflammatory molecules. Nrf2 is a multifunctional cytoprotective transcription factor that regulates the expression of various antioxidant, anti-inflammatory, and detoxifying molecules, such...

Activation of GATA-binding protein 4 regulates monocyte chemoattractant protein-1 and chemotaxis in periodontal ligament cells.

Journal of periodontal research

Zhu N, Zheng X, Qiao W, Huang W, Li R, Song Y.
PMID: 34773653
J Periodontal Res. 2022 Jan;57(1):195-204. doi: 10.1111/jre.12953. Epub 2021 Nov 13.

BACKGROUND AND OBJECTIVES: Periodontitis is a chronic inflammatory disease of periodontal supporting tissues. The persistent inflammatory reaction depends on the release of chemokines to continuously recruit inflammation cells. GATA-binding protein 4 (GATA4) exerts effects on senescence and inflammation, while...

Showing 25 to 36 of 64 entries