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Showing 265 to 275 of 275 entries
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The Role of Surfactin Production by .

Microorganisms

Stoll A, Salvatierra-Martínez R, González M, Araya M.
PMID: 34835375
Microorganisms. 2021 Oct 28;9(11). doi: 10.3390/microorganisms9112251.

Many aspects regarding the role of lipopeptides (LPs) in bacterial interaction with plants are not clear yet. Of particular interest is the LP family of surfactin, immunogenic molecules involved in induced systemic resistance (ISR) and the bacterial colonization of...

Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide.

Cell

Xue J, Chong H, Zhu Y, Zhang J, Tong L, Lu J, Chen T, Cong Z, Wei Q, He Y.
PMID: 34919814
Cell. 2021 Dec 09; doi: 10.1016/j.cell.2021.11.032. Epub 2021 Dec 09.

Two HIV fusion-inhibitory lipopeptides (LP-97 and LP-98) were designed with highly potent, long-acting antiviral activity. Monotherapy using a low dose of LP-98 sharply reduced viral loads and maintained long-term viral suppression in 21 SHIV

Airway Epithelial Innate Immunity.

Frontiers in physiology

Johnston SL, Goldblatt DL, Evans SE, Tuvim MJ, Dickey BF.
PMID: 34899381
Front Physiol. 2021 Nov 26;12:749077. doi: 10.3389/fphys.2021.749077. eCollection 2021.

Besides providing an essential protective barrier, airway epithelial cells directly sense pathogens and respond defensively. This is a frontline component of the innate immune system with specificity for different pathogen classes. It occurs in the context of numerous interactions...

Isolation and Characterization of Fengycins Produced by .

Frontiers in microbiology

Lin LZ, Zheng QW, Wei T, Zhang ZQ, Zhao CF, Zhong H, Xu QY, Lin JF, Guo LQ.
PMID: 33391199
Front Microbiol. 2020 Dec 18;11:579621. doi: 10.3389/fmicb.2020.579621. eCollection 2020.

The continuing emergence and development of pathogenic microorganisms that are resistant to antibiotics constitute an increasing global concern, and the effort in new antimicrobials discovery will remain relevant until a lasting solution is found. A new bacterial strain, designated...

Combined delivery of TLR2 and TLR7 agonists by Nanostructured lipid carriers induces potent vaccine adjuvant activity in mice.

International journal of pharmaceutics

Kaur A, Kanwar R, Kaushik D, Sakala IG, Honda-Okubo Y, Petrovsky N, Salunke DB, Mehta SK.
PMID: 34915144
Int J Pharm. 2021 Dec 13;613:121378. doi: 10.1016/j.ijpharm.2021.121378. Epub 2021 Dec 13.

Toll-like receptor (TLR) agonists are promising adjuvants and the combination of TLR agonists enhance immune responses by providing synergistic immune activity via triggering different signalling pathways. However, systematic cytotoxicity due to the immediate release of such immune potentiators from...

Combined delivery of TLR2 and TLR7 agonists by Nanostructured Lipid Carriers Induces Potent Vaccine Adjuvant Activity in Mice.

International journal of pharmaceutics

Kaur A, Kanwar R, Kaushik D, Sakala IG, Honda-Okubo Y, Petrovsky N, Salunke DB, Mehta SK.
PMID: 34915144
Int J Pharm. 2021 Dec 13;121378. doi: 10.1016/j.ijpharm.2021.121378. Epub 2021 Dec 13.

Toll-like receptor (TLR) agonists are promising adjuvants and the combination of TLR agonists enhance immune responses by providing synergistic immune activity via triggering different signalling pathways. However, systematic cytotoxicity due to the immediate release of such immune potentiators from...

Surface properties and heavy metals chelation of lipopeptides biosurfactants produced from date flour by Bacillus subtilis ZNI5: optimized production for application in bioremediation.

Bioprocess and biosystems engineering

Mnif I, Bouallegue A, Bouassida M, Ghribi D.
PMID: 34807299
Bioprocess Biosyst Eng. 2022 Jan;45(1):31-44. doi: 10.1007/s00449-021-02635-2. Epub 2021 Nov 22.

The present study summarizes the valorization of date flour by the production of lipopeptide biosurfactant (BioS) by Bacillus subtilis ZNI5 (MW091416). A Taguchi design permitted the formulation of a medium composed only of 6% date flour and 0.5% yeast...

Iranian journal of basic medical sciences

Etemadzadeh SS, Emtiazi G.
PMID: 34249269
Iran J Basic Med Sci. 2021 May;24(5):666-674. doi: 10.22038/IJBMS.2021.53419.12022.

OBJECTIVES: The multi-drug resistant bacteria and clinical infections are some of the biggest global concerns, so new drugs are needed. Antimicrobial peptides and lipopeptides are new bioactive agents with great potential that can become a new strategy for clinical...

Combined delivery of TLR2 and TLR7 agonists by Nanostructured lipid carriers induces potent vaccine adjuvant activity in mice.

International journal of pharmaceutics

Kaur A, Kanwar R, Kaushik D, Sakala IG, Honda-Okubo Y, Petrovsky N, Salunke DB, Mehta SK.
PMID: 34915144
Int J Pharm. 2021 Dec 13;613:121378. doi: 10.1016/j.ijpharm.2021.121378. Epub 2021 Dec 13.

Toll-like receptor (TLR) agonists are promising adjuvants and the combination of TLR agonists enhance immune responses by providing synergistic immune activity via triggering different signalling pathways. However, systematic cytotoxicity due to the immediate release of such immune potentiators from...

Relationship between lipopeptide biosurfactant and primary metabolite production by Bacillus strains in solid-state and submerged fermentation.

Bioresource technology

Valdés-Velasco LM, Favela-Torres E, Théatre A, Arguelles-Arias A, Saucedo-Castañeda JG, Jacques P.
PMID: 34923080
Bioresour Technol. 2021 Dec 16;345:126556. doi: 10.1016/j.biortech.2021.126556. Epub 2021 Dec 16.

The relationship between lipopeptide and primary metabolite production by Bacillus spp. in solid-state fermentation (SSF) and submerged fermentation (SmF) was evaluated. Four wild-type strains and one mutant strain (unable to develop biofilm) were assessed in SSF and SmF, using...

Liposomes for the Delivery of Lipopeptide Vaccines.

Methods in molecular biology (Clifton, N.J.)

Yang J, Azuar A, Toth I, Skwarczynski M.
PMID: 34918252
Methods Mol Biol. 2022;2412:295-307. doi: 10.1007/978-1-0716-1892-9_15.

Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation...

Showing 265 to 275 of 275 entries