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Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Human genomics

Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY.
PMID: 31092297
Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7.

BACKGROUND: End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease...

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Guan M, Keaton JM, Dimitrov L, et al. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019;13(1):21doi: 10.1186/s40246-019-0205-7.
Guan, M., Keaton, J. M., Dimitrov, L., Hicks, P. J., Xu, J., Palmer, N. D., Ma, L., Das, S. K., Chen, Y. I., Coresh, J., Fornage, M., Franceschini, N., Kramer, H., Langefeld, C. D., Mychaleckyj, J. C., Parekh, R. S., Post, W. S., Rasmussen-Torvik, L. J., Rich, S. S., Rotter, J. I., Sedor, J. R., Thornley-Brown, D., Tin, A., Wilson, J. G., Freedman, B. I., Bowden, D. W., Ng, M. C. Y. (2019). Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human genomics, 13(1), 21. https://doi.org/10.1186/s40246-019-0205-7
Guan, Meijian, et al. "Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Human genomics vol. 13,1 (2019): 21. doi: https://doi.org/10.1186/s40246-019-0205-7
Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7. PMID: 31092297; PMCID: PMC6521376.
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Weight gain in infancy and early childhood is associated with school age body mass index but not intelligence and blood pressure in very low birth weight children.

Journal of developmental origins of health and disease

Washburn L, Nixon P, Snively B, Tennyson A, O'Shea TM.
PMID: 22962630
J Dev Orig Health Dis. 2010 Oct;1(5):338-46. doi: 10.1017/S2040174410000401.

Rates of weight gain in infancy and early childhood can influence later neurocognitive, metabolic and cardiovascular health. We studied the relationship of weight gain during infancy and early childhood to intelligence quotient (IQ), blood pressure (BP) and body mass...

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Washburn L, Nixon P, Snively B, et al. Weight gain in infancy and early childhood is associated with school age body mass index but not intelligence and blood pressure in very low birth weight children. J Dev Orig Health Dis. 2010;1(5):338-46doi: 10.1017/S2040174410000401.
Washburn, L., Nixon, P., Snively, B., Tennyson, A., & O'Shea, T. M. (2010). Weight gain in infancy and early childhood is associated with school age body mass index but not intelligence and blood pressure in very low birth weight children. Journal of developmental origins of health and disease, 1(5), 338-46. https://doi.org/10.1017/S2040174410000401
Washburn, L, et al. "Weight gain in infancy and early childhood is associated with school age body mass index but not intelligence and blood pressure in very low birth weight children." Journal of developmental origins of health and disease vol. 1,5 (2010): 338-46. doi: https://doi.org/10.1017/S2040174410000401
Washburn L, Nixon P, Snively B, Tennyson A, O'Shea TM. Weight gain in infancy and early childhood is associated with school age body mass index but not intelligence and blood pressure in very low birth weight children. J Dev Orig Health Dis. 2010 Oct;1(5):338-46. doi: 10.1017/S2040174410000401. PMID: 22962630; PMCID: PMC3434458.
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Update on heart failure with preserved ejection fraction.

Current cardiovascular risk reports

Hummel SL, Kitzman DW.
PMID: 24860638
Curr Cardiovasc Risk Rep. 2013 Dec;7(6):495-502. doi: 10.1007/s12170-013-0350-9.

Heart failure with preserved ejection fraction (HFPEF) is the most common form of heart failure (HF) in older adults, and is increasing in prevalence as the population ages. Morbidity and long-term mortality in HFPEF are substantial and can be...

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Hummel SL, Kitzman DW. Update on heart failure with preserved ejection fraction. Curr Cardiovasc Risk Rep. 2013;7(6):495-502doi: 10.1007/s12170-013-0350-9.
Hummel, S. L., & Kitzman, D. W. (2013). Update on heart failure with preserved ejection fraction. Current cardiovascular risk reports, 7(6), 495-502. https://doi.org/10.1007/s12170-013-0350-9
Hummel, Scott L, and Kitzman, Dalane W. "Update on heart failure with preserved ejection fraction." Current cardiovascular risk reports vol. 7,6 (2013): 495-502. doi: https://doi.org/10.1007/s12170-013-0350-9
Hummel SL, Kitzman DW. Update on heart failure with preserved ejection fraction. Curr Cardiovasc Risk Rep. 2013 Dec;7(6):495-502. doi: 10.1007/s12170-013-0350-9. PMID: 24860638; PMCID: PMC4028705.
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Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants.

Archives of disease in childhood. Fetal and neonatal edition

Salas AA, Carlo WA, Ambalavanan N, Nolen TL, Stoll BJ, Das A, Higgins RD.
PMID: 26895876
Arch Dis Child Fetal Neonatal Ed. 2016 Nov;101(6):F494-F501. doi: 10.1136/archdischild-2015-309670. Epub 2016 Feb 19.

BACKGROUND: The risk of poor outcomes in preterm infants is primarily determined by birthweight (BW) and gestational age (GA). It is not known whether BW is a better outcome predictor than GA.OBJECTIVE: To test whether BW is better than...

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Salas AA, Carlo WA, Ambalavanan N, et al. Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants. Arch Dis Child Fetal Neonatal Ed. 2016;101(6):F494-F501doi: 10.1136/archdischild-2015-309670.
Salas, A. A., Carlo, W. A., Ambalavanan, N., Nolen, T. L., Stoll, B. J., Das, A., Higgins, R. D. (2016). Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants. Archives of disease in childhood. Fetal and neonatal edition, 101(6), F494-F501. https://doi.org/10.1136/archdischild-2015-309670
Salas, Ariel A, et al. "Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants." Archives of disease in childhood. Fetal and neonatal edition vol. 101,6 (2016): F494-F501. doi: https://doi.org/10.1136/archdischild-2015-309670
Salas AA, Carlo WA, Ambalavanan N, Nolen TL, Stoll BJ, Das A, Higgins RD. Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants. Arch Dis Child Fetal Neonatal Ed. 2016 Nov;101(6):F494-F501. doi: 10.1136/archdischild-2015-309670. Epub 2016 Feb 19. PMID: 26895876; PMCID: PMC4991950.
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Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults.

International journal of biomedical imaging

Peiffer AM, Maldjian JA, Laurienti PJ.
PMID: 18274664
Int J Biomed Imaging. 2008;2008:167078. doi: 10.1155/2008/167078.

By plotting response times of young and older adults across a variety of tasks, Brinley spurred investigation and debate into the theory of general cognitive slowing. Though controversial, Brinley plots can assess between-task differences, the impact of increasing task...

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Peiffer AM, Maldjian JA, Laurienti PJ. Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults. Int J Biomed Imaging. 2008;2008:167078doi: 10.1155/2008/167078.
Peiffer, A. M., Maldjian, J. A., & Laurienti, P. J. (2008). Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults. International journal of biomedical imaging, 2008167078. https://doi.org/10.1155/2008/167078
Peiffer, Ann M, et al. "Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults." International journal of biomedical imaging vol. 2008 (2008): 167078. doi: https://doi.org/10.1155/2008/167078
Peiffer AM, Maldjian JA, Laurienti PJ. Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults. Int J Biomed Imaging. 2008;2008:167078. doi: 10.1155/2008/167078. PMID: 18274664; PMCID: PMC2233772.
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Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women.

Journal of obesity

Wang X, Nicklas BJ.
PMID: 20847895
J Obes. 2011;2011. doi: 10.1155/2011/342431. Epub 2010 Aug 10.

This study determined whether performing a single moderate- or vigorous-intensity exercise bout impacts daily physical activity energy expenditure (PAEE, by accelerometer). Overweight/obese postmenopausal women underwent a 5-month caloric restriction and moderate- (n = 18) or vigorous-intensity (n = 18)...

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Wang X, Nicklas BJ. Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women. J Obes. 2010;2011doi: 10.1155/2011/342431.
Wang, X., & Nicklas, B. J. (2011). Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women. Journal of obesity, 2011. https://doi.org/10.1155/2011/342431
Wang, Xuewen, and Nicklas, Barbara J. "Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women." Journal of obesity vol. 2011 (2011). doi: https://doi.org/10.1155/2011/342431
Wang X, Nicklas BJ. Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women. J Obes. 2011;2011. doi: 10.1155/2011/342431. Epub 2010 Aug 10. PMID: 20847895; PMCID: PMC2931398.
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Changes in cognitive state alter human functional brain networks.

Frontiers in human neuroscience

Moussa MN, Vechlekar CD, Burdette JH, Steen MR, Hugenschmidt CE, Laurienti PJ.
PMID: 21991252
Front Hum Neurosci. 2011 Aug 22;5:83. doi: 10.3389/fnhum.2011.00083. eCollection 2011.

The study of the brain as a whole system can be accomplished using network theory principles. Research has shown that human functional brain networks during a resting state exhibit small-world properties and high degree nodes, or hubs, localized to...

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Moussa MN, Vechlekar CD, Burdette JH, et al. Changes in cognitive state alter human functional brain networks. Front Hum Neurosci. 2011;5:83doi: 10.3389/fnhum.2011.00083.
Moussa, M. N., Vechlekar, C. D., Burdette, J. H., Steen, M. R., Hugenschmidt, C. E., & Laurienti, P. J. (2011). Changes in cognitive state alter human functional brain networks. Frontiers in human neuroscience, 583. https://doi.org/10.3389/fnhum.2011.00083
Moussa, Malaak Nasser, et al. "Changes in cognitive state alter human functional brain networks." Frontiers in human neuroscience vol. 5 (2011): 83. doi: https://doi.org/10.3389/fnhum.2011.00083
Moussa MN, Vechlekar CD, Burdette JH, Steen MR, Hugenschmidt CE, Laurienti PJ. Changes in cognitive state alter human functional brain networks. Front Hum Neurosci. 2011 Aug 22;5:83. doi: 10.3389/fnhum.2011.00083. eCollection 2011. PMID: 21991252; PMCID: PMC3159402.
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Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy.

American journal of ophthalmology

Sobrin L, Susarla G, Stanwyck L, Rouhana JM, Li A, Pollack S, Igo RP, Jensen RA, Li X, Ng MCY, Smith AV, Kuo JZ, Taylor KD, Freedman BI, Bowden DW, Penman A, Chen CJ, Craig JE, Adler SG, Chew EY, Cotch MF, Yaspan B, Mitchell P, Wang JJ, Klein BEK, Wong TY, Rotter JI, Burdon KP, Iyengar SK, Segrè AV.
PMID: 34166655
Am J Ophthalmol. 2022 Jan;233:111-123. doi: 10.1016/j.ajo.2021.06.014. Epub 2021 Jun 21.

To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses applied to genome-wide association study meta-analyses.METHODS: We analyzed DR GWAS meta-analyses performed on 3246 Europeans and 2611 African Americans with type 2 diabetes....

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Sobrin L, Susarla G, Stanwyck L, et al. Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Am J Ophthalmol. 2021;233:111-123doi: 10.1016/j.ajo.2021.06.014.
Sobrin, L., Susarla, G., Stanwyck, L., Rouhana, J. M., Li, A., Pollack, S., Igo, R. P., Jensen, R. A., Li, X., Ng, M. C. Y., Smith, A. V., Kuo, J. Z., Taylor, K. D., Freedman, B. I., Bowden, D. W., Penman, A., Chen, C. J., Craig, J. E., Adler, S. G., Chew, E. Y., Cotch, M. F., Yaspan, B., Mitchell, P., Wang, J. J., Klein, B. E. K., Wong, T. Y., Rotter, J. I., Burdon, K. P., Iyengar, S. K., & Segrè, A. V. (2022). Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. American journal of ophthalmology, 233111-123. https://doi.org/10.1016/j.ajo.2021.06.014
Sobrin, Lucia, et al. "Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy." American journal of ophthalmology vol. 233 (2022): 111-123. doi: https://doi.org/10.1016/j.ajo.2021.06.014
Sobrin L, Susarla G, Stanwyck L, Rouhana JM, Li A, Pollack S, Igo RP, Jensen RA, Li X, Ng MCY, Smith AV, Kuo JZ, Taylor KD, Freedman BI, Bowden DW, Penman A, Chen CJ, Craig JE, Adler SG, Chew EY, Cotch MF, Yaspan B, Mitchell P, Wang JJ, Klein BEK, Wong TY, Rotter JI, Burdon KP, Iyengar SK, Segrè AV. Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Am J Ophthalmol. 2022 Jan;233:111-123. doi: 10.1016/j.ajo.2021.06.014. Epub 2021 Jun 21. PMID: 34166655; PMCID: PMC8678352.
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Showing 13 to 20 of 20 entries