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Improved efficacy of meglumine antimoniate incorporated in anionic liposomes against Leishmania infantum infecting canine macrophages.

The Journal of pharmacy and pharmacology

Ortega V, Radaic A, de Jesus MB, de Paula E, Giorgio S.
PMID: 34289045
J Pharm Pharmacol. 2021 Jul 21; doi: 10.1093/jpp/rgab081. Epub 2021 Jul 21.

OBJECTIVES: Leishmaniasis is a zoonotic disease and several drugs have been used in the treatment, including meglumine antimoniate (AME). The chemotherapy reaches clinical cure but does not eliminate parasites, contributing to drug resistance. To improve AME efficacy we incorporated...

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Ortega V, Radaic A, de Jesus MB, et al. Improved efficacy of meglumine antimoniate incorporated in anionic liposomes against Leishmania infantum infecting canine macrophages. J Pharm Pharmacol. 2021;doi: 10.1093/jpp/rgab081.
Ortega, V., Radaic, A., de Jesus, M. B., de Paula, E., & Giorgio, S. (2021). Improved efficacy of meglumine antimoniate incorporated in anionic liposomes against Leishmania infantum infecting canine macrophages. The Journal of pharmacy and pharmacology, . https://doi.org/10.1093/jpp/rgab081
Ortega, Vanessa, et al. "Improved efficacy of meglumine antimoniate incorporated in anionic liposomes against Leishmania infantum infecting canine macrophages." The Journal of pharmacy and pharmacology vol. (2021). doi: https://doi.org/10.1093/jpp/rgab081
Ortega V, Radaic A, de Jesus MB, de Paula E, Giorgio S. Improved efficacy of meglumine antimoniate incorporated in anionic liposomes against Leishmania infantum infecting canine macrophages. J Pharm Pharmacol. 2021 Jul 21; doi: 10.1093/jpp/rgab081. Epub 2021 Jul 21. PMID: 34289045.
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An old drug and different ways to treat cutaneous leishmaniasis: Intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil.

PLoS neglected tropical diseases

Oliveira-Ribeiro C, Pimentel MIF, Oliveira LFA, Vasconcellos ÉCFE, Conceição-Silva F, Schubach AO, Fagundes A, de Mello CX, Mouta-Confort E, Miranda LFC, Valete-Rosalino CM, Martins ACDC, Oliveira RVC, Quintella LP, Lyra MR.
PMID: 34555016
PLoS Negl Trop Dis. 2021 Sep 23;15(9):e0009734. doi: 10.1371/journal.pntd.0009734. eCollection 2021 Sep.

BACKGROUND: Treatment of cutaneous leishmaniasis (CL) remains challenging since the drugs currently used are quite toxic, thus contributing to lethality unrelated to the disease itself but to adverse events (AE). The main objective was to evaluate different treatment regimens...

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Oliveira-Ribeiro C, Pimentel MIF, Oliveira LFA, et al. An old drug and different ways to treat cutaneous leishmaniasis: Intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil. PLoS Negl Trop Dis. 2021;15(9):e0009734doi: 10.1371/journal.pntd.0009734.
Oliveira-Ribeiro, C., Pimentel, M. I. F., Oliveira, L. F. A., Vasconcellos, �. �. C. F. E., Conceição-Silva, F., Schubach, A. O., Fagundes, A., de Mello, C. X., Mouta-Confort, E., Miranda, L. F. C., Valete-Rosalino, C. M., Martins, A. C. D. C., Oliveira, R. V. C., Quintella, L. P., & Lyra, M. R. (2021). An old drug and different ways to treat cutaneous leishmaniasis: Intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil. PLoS neglected tropical diseases, 15(9), e0009734. https://doi.org/10.1371/journal.pntd.0009734
Oliveira-Ribeiro, Carla, et al. "An old drug and different ways to treat cutaneous leishmaniasis: Intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil." PLoS neglected tropical diseases vol. 15,9 (2021): e0009734. doi: https://doi.org/10.1371/journal.pntd.0009734
Oliveira-Ribeiro C, Pimentel MIF, Oliveira LFA, Vasconcellos ÉCFE, Conceição-Silva F, Schubach AO, Fagundes A, de Mello CX, Mouta-Confort E, Miranda LFC, Valete-Rosalino CM, Martins ACDC, Oliveira RVC, Quintella LP, Lyra MR. An old drug and different ways to treat cutaneous leishmaniasis: Intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil. PLoS Negl Trop Dis. 2021 Sep 23;15(9):e0009734. doi: 10.1371/journal.pntd.0009734. eCollection 2021 Sep. PMID: 34555016; PMCID: PMC8491910.
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Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis.

Nanomedicine : nanotechnology, biology, and medicine

Khalid S, Salman S, Iqbal K, Rehman FU, Ullah I, Satoskar AR, Khan GM, Dar MJ.
PMID: 34748957
Nanomedicine. 2021 Nov 05;40:102490. doi: 10.1016/j.nano.2021.102490. Epub 2021 Nov 05.

The basic aim of the study was to develop and evaluate the triple drug loaded cationic nano-vesicles (cNVs), where miltefosine was used as a replacement of surfactant (apart from its anti-leishmanial role), in addition to meglumine antimoniate (MAM) and...

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Khalid S, Salman S, Iqbal K, et al. Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis. Nanomedicine. 2021;40:102490doi: 10.1016/j.nano.2021.102490.
Khalid, S., Salman, S., Iqbal, K., Rehman, F. U., Ullah, I., Satoskar, A. R., Khan, G. M., & Dar, M. J. (2021). Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis. Nanomedicine : nanotechnology, biology, and medicine, 40102490. https://doi.org/10.1016/j.nano.2021.102490
Khalid, Sidra, et al. "Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis." Nanomedicine : nanotechnology, biology, and medicine vol. 40 (2021): 102490. doi: https://doi.org/10.1016/j.nano.2021.102490
Khalid S, Salman S, Iqbal K, Rehman FU, Ullah I, Satoskar AR, Khan GM, Dar MJ. Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis. Nanomedicine. 2021 Nov 05;40:102490. doi: 10.1016/j.nano.2021.102490. Epub 2021 Nov 05. PMID: 34748957.
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Combination of topical liposomal amphotericin B and Glucantime in comparison with glucantime alone for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by .

Iranian journal of microbiology

Eskandari SE, Khamesipour A, Jaafari MR, Javadi A, Mohammadi AM, Valian HK, Nassiri-Kashani M, Goyonlo VM, Firooz A.
PMID: 34900170
Iran J Microbiol. 2021 Oct;13(5):718-723. doi: 10.18502/ijm.v13i5.7440.

BACKGROUND AND OBJECTIVES: Cutaneous leishmaniasis (CL) treatment is a challenging issue, although numerous modalities have been introduced as candidate treatment for CL yet only antimonial agents are commonly used to treat CL, a different form of amphotericin B is...

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Eskandari SE, Khamesipour A, Jaafari MR, et al. Combination of topical liposomal amphotericin B and Glucantime in comparison with glucantime alone for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by . Iran J Microbiol. 2021;13(5):718-723doi: 10.18502/ijm.v13i5.7440.
Eskandari, S. E., Khamesipour, A., Jaafari, M. R., Javadi, A., Mohammadi, A. M., Valian, H. K., Nassiri-Kashani, M., Goyonlo, V. M., & Firooz, A. (2021). Combination of topical liposomal amphotericin B and Glucantime in comparison with glucantime alone for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by . Iranian journal of microbiology, 13(5), 718-723. https://doi.org/10.18502/ijm.v13i5.7440
Eskandari, Seyed Ebrahim, et al. "Combination of topical liposomal amphotericin B and Glucantime in comparison with glucantime alone for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by ." Iranian journal of microbiology vol. 13,5 (2021): 718-723. doi: https://doi.org/10.18502/ijm.v13i5.7440
Eskandari SE, Khamesipour A, Jaafari MR, Javadi A, Mohammadi AM, Valian HK, Nassiri-Kashani M, Goyonlo VM, Firooz A. Combination of topical liposomal amphotericin B and Glucantime in comparison with glucantime alone for the treatment of anthroponotic cutaneous leishmaniasis (ACL) caused by . Iran J Microbiol. 2021 Oct;13(5):718-723. doi: 10.18502/ijm.v13i5.7440. PMID: 34900170; PMCID: PMC8629814.
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New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate.

Clinical case reports

Daadaa N, Youssef S, Haggui A, Harbaoui S, Jaber K, Doss N, Dhaoui MR.
PMID: 33768944
Clin Case Rep. 2021 Jan 16;9(3):1797-1798. doi: 10.1002/ccr3.3768. eCollection 2021 Mar.

The sinoatrial block is a new side effect of meglumine antimoniate. Prompt interruption of the drug results in the normalization of electrographic changes and prevents sudden cardiac arrest.

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Daadaa N, Youssef S, Haggui A, et al. New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate. Clin Case Rep. 2021;9(3):1797-1798doi: 10.1002/ccr3.3768.
Daadaa, N., Youssef, S., Haggui, A., Harbaoui, S., Jaber, K., Doss, N., & Dhaoui, M. R. (2021). New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate. Clinical case reports, 9(3), 1797-1798. https://doi.org/10.1002/ccr3.3768
Daadaa, Najla, et al. "New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate." Clinical case reports vol. 9,3 (2021): 1797-1798. doi: https://doi.org/10.1002/ccr3.3768
Daadaa N, Youssef S, Haggui A, Harbaoui S, Jaber K, Doss N, Dhaoui MR. New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate. Clin Case Rep. 2021 Jan 16;9(3):1797-1798. doi: 10.1002/ccr3.3768. eCollection 2021 Mar. PMID: 33768944; PMCID: PMC7981715.
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The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child with Chronic Granulomatous Disease: A Case Report.

Iranian journal of parasitology

Abdolsalehi MR, Mohebali M, Keshavarz H, Mahmoudi S, Mamishi S.
PMID: 33786058
Iran J Parasitol. 2021 Jan-Mar;16(1):159-163. doi: 10.18502/ijpa.v16i1.5536.

Chronic granulomatous disease (CGD) described as an essential immunodeficiency problem of phagocytic cells resulting in a phagocyte dysfunction and inability to kill a spectrum of bacteria and fungi. Despite the fact that CGD patients are more susceptible to intracellular...

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Abdolsalehi MR, Mohebali M, Keshavarz H, et al. The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child with Chronic Granulomatous Disease: A Case Report. Iran J Parasitol. 2021;16(1):159-163doi: 10.18502/ijpa.v16i1.5536.
Abdolsalehi, M. R., Mohebali, M., Keshavarz, H., Mahmoudi, S., & Mamishi, S. (2021). The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child with Chronic Granulomatous Disease: A Case Report. Iranian journal of parasitology, 16(1), 159-163. https://doi.org/10.18502/ijpa.v16i1.5536
Abdolsalehi, Mohammad Reza, et al. "The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child with Chronic Granulomatous Disease: A Case Report." Iranian journal of parasitology vol. 16,1 (2021): 159-163. doi: https://doi.org/10.18502/ijpa.v16i1.5536
Abdolsalehi MR, Mohebali M, Keshavarz H, Mahmoudi S, Mamishi S. The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child with Chronic Granulomatous Disease: A Case Report. Iran J Parasitol. 2021 Jan-Mar;16(1):159-163. doi: 10.18502/ijpa.v16i1.5536. PMID: 33786058; PMCID: PMC7988672.
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Showing 97 to 102 of 102 entries