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Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics.

CPT: pharmacometrics & systems pharmacology

Lenoir C, Niederer A, Rollason V, Desmeules JA, Daali Y, Samer CF.
PMID: 34791831
CPT Pharmacometrics Syst Pharmacol. 2022 Jan;11(1):30-43. doi: 10.1002/psp4.12730. Epub 2021 Nov 17.

Xenobiotics can interact with cytochromes P450 (CYPs), resulting in drug-drug interactions, but CYPs can also contribute to drug-disease interactions, especially in the case of inflammation, which downregulates CYP activities through pretranscriptional and posttranscriptional mechanisms. Interleukin-6 (IL-6), a key proinflammatory...

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Lenoir C, Niederer A, Rollason V, et al. Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics. CPT Pharmacometrics Syst Pharmacol. 2021;11(1):30-43doi: 10.1002/psp4.12730.
Lenoir, C., Niederer, A., Rollason, V., Desmeules, J. A., Daali, Y., & Samer, C. F. (2022). Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics. CPT: pharmacometrics & systems pharmacology, 11(1), 30-43. https://doi.org/10.1002/psp4.12730
Lenoir, Camille, et al. "Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics." CPT: pharmacometrics & systems pharmacology vol. 11,1 (2022): 30-43. doi: https://doi.org/10.1002/psp4.12730
Lenoir C, Niederer A, Rollason V, Desmeules JA, Daali Y, Samer CF. Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics. CPT Pharmacometrics Syst Pharmacol. 2022 Jan;11(1):30-43. doi: 10.1002/psp4.12730. Epub 2021 Nov 17. PMID: 34791831.
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Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy.

Medicine

Horikoshi Y, Kuratani N, Tateno K, Hoshijima H, Nakamura T, Mieda T, Doi K, Nagasaka H.
PMID: 34889305
Medicine (Baltimore). 2021 Dec 10;100(49):e28209. doi: 10.1097/MD.0000000000028209.

RATIONALE: With Duchenne muscular dystrophy (DMD) being the most common and most severe type of muscular dystrophy, DMD patients are at risk for complications from general anesthesia due to impaired cardiac and respiratory functions as the pathological condition progresses....

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Horikoshi Y, Kuratani N, Tateno K, et al. Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy. Medicine (Baltimore). 2021;100(49):e28209doi: 10.1097/MD.0000000000028209.
Horikoshi, Y., Kuratani, N., Tateno, K., Hoshijima, H., Nakamura, T., Mieda, T., Doi, K., & Nagasaka, H. (2021). Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy. Medicine, 100(49), e28209. https://doi.org/10.1097/MD.0000000000028209
Horikoshi, Yuta, et al. "Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy." Medicine vol. 100,49 (2021): e28209. doi: https://doi.org/10.1097/MD.0000000000028209
Horikoshi Y, Kuratani N, Tateno K, Hoshijima H, Nakamura T, Mieda T, Doi K, Nagasaka H. Anesthetic management with remimazolam for a pediatric patient with Duchenne muscular dystrophy. Medicine (Baltimore). 2021 Dec 10;100(49):e28209. doi: 10.1097/MD.0000000000028209. PMID: 34889305; PMCID: PMC8663901.
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Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia.

Pediatric emergency care

Tel-Dan SF, Shavit D, Nates R, Samuel N, Shavit I.
PMID: 31929389
Pediatr Emerg Care. 2021 Dec 01;37(12):e1209-e1212. doi: 10.1097/PEC.0000000000001975.

BACKGROUND: Thoracostomy drainage is sometimes required in children with pleuropneumonia who have large parapneumonic effusion. This procedure is usually performed under sedation. The aim was to report sedation adverse events (SAEs) in pneumonia patients sedated for thoracostomy by pediatric...

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Tel-Dan SF, Shavit D, Nates R, et al. Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia. Pediatr Emerg Care. 2021;37(12):e1209-e1212doi: 10.1097/PEC.0000000000001975.
Tel-Dan, S. F., Shavit, D., Nates, R., Samuel, N., & Shavit, I. (2021). Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia. Pediatric emergency care, 37(12), e1209-e1212. https://doi.org/10.1097/PEC.0000000000001975
Tel-Dan, Shira Fajnerman, et al. "Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia." Pediatric emergency care vol. 37,12 (2021): e1209-e1212. doi: https://doi.org/10.1097/PEC.0000000000001975
Tel-Dan SF, Shavit D, Nates R, Samuel N, Shavit I. Emergency Physician-Administered Sedation for Thoracostomy in Children With Pleuropneumonia. Pediatr Emerg Care. 2021 Dec 01;37(12):e1209-e1212. doi: 10.1097/PEC.0000000000001975. PMID: 31929389.
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Variation in Prehospital Protocols for Pediatric Seizure Within the United States.

Pediatric emergency care

Ramgopal S, McCans K, Martin-Gill C, Owusu-Ansah S.
PMID: 32011553
Pediatr Emerg Care. 2021 Dec 01;37(12):e1331-e1338. doi: 10.1097/PEC.0000000000002029.

OBJECTIVE: The objective of this study was to compare statewide prehospital protocols for the management of pediatric seizures.METHODS: We performed a descriptive analysis comparing statewide protocols for emergency medical services management of pediatric seizures within the United States, excluding...

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Ramgopal S, McCans K, Martin-Gill C, et al. Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatr Emerg Care. 2021;37(12):e1331-e1338doi: 10.1097/PEC.0000000000002029.
Ramgopal, S., McCans, K., Martin-Gill, C., & Owusu-Ansah, S. (2021). Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatric emergency care, 37(12), e1331-e1338. https://doi.org/10.1097/PEC.0000000000002029
Ramgopal, Sriram, et al. "Variation in Prehospital Protocols for Pediatric Seizure Within the United States." Pediatric emergency care vol. 37,12 (2021): e1331-e1338. doi: https://doi.org/10.1097/PEC.0000000000002029
Ramgopal S, McCans K, Martin-Gill C, Owusu-Ansah S. Variation in Prehospital Protocols for Pediatric Seizure Within the United States. Pediatr Emerg Care. 2021 Dec 01;37(12):e1331-e1338. doi: 10.1097/PEC.0000000000002029. PMID: 32011553.
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Showing 1597 to 1600 of 1600 entries