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GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?.

Frontiers in behavioral neuroscience

Cunha C, Monfils MH, Ledoux JE.
PMID: 20300199
Front Behav Neurosci. 2010 Mar 12;4:6. doi: 10.3389/neuro.08.006.2010. eCollection 2010.

Activation of GABA(A)Rs in the lateral nucleus of the amygdala (LA), a key site of plasticity underlying fear learning, impairs fear learning. The role of GABA(C)Rs in the LA and other brain areas is poorly understood. GABA(C)Rs could be...

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Cunha C, Monfils MH, Ledoux JE. GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?. Front Behav Neurosci. 2010;4:6doi: 10.3389/neuro.08.006.2010.
Cunha, C., Monfils, M. H., & Ledoux, J. E. (2010). GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?. Frontiers in behavioral neuroscience, 46. https://doi.org/10.3389/neuro.08.006.2010
Cunha, Catarina, et al. "GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?." Frontiers in behavioral neuroscience vol. 4 (2010): 6. doi: https://doi.org/10.3389/neuro.08.006.2010
Cunha C, Monfils MH, Ledoux JE. GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?. Front Behav Neurosci. 2010 Mar 12;4:6. doi: 10.3389/neuro.08.006.2010. eCollection 2010. PMID: 20300199; PMCID: PMC2841484.
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Gamma-Aminobutyric Acid Modulation of Corticotrophin-Releasing Factor-41 Secretion from the Rat Hypothalamus in vitro.

Journal of neuroendocrinology

Tsagarakis S, Rees LH, Besser GM, Grossman A.
PMID: 19210387
J Neuroendocrinol. 1990 Apr 01;2(2):221-4. doi: 10.1111/j.1365-2826.1990.tb00854.x.

Abstract There is increasing evidence for a centrally mediated inhibitory effect of the amino-acid neurotransmitter y-aminobutyric acid (GABA) on the hypothalamo-pituitary-adrenal axis. In the present study, the direct effect of GABA in modulating the release of the 41-residue corticotrophin-releasing...

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Tsagarakis S, Rees LH, Besser GM, et al. Gamma-Aminobutyric Acid Modulation of Corticotrophin-Releasing Factor-41 Secretion from the Rat Hypothalamus in vitro. J Neuroendocrinol. 1990;2(2):221-4doi: 10.1111/j.1365-2826.1990.tb00854.x.
Tsagarakis, S., Rees, L. H., Besser, G. M., & Grossman, A. (1990). Gamma-Aminobutyric Acid Modulation of Corticotrophin-Releasing Factor-41 Secretion from the Rat Hypothalamus in vitro. Journal of neuroendocrinology, 2(2), 221-4. https://doi.org/10.1111/j.1365-2826.1990.tb00854.x
Tsagarakis, S, et al. "Gamma-Aminobutyric Acid Modulation of Corticotrophin-Releasing Factor-41 Secretion from the Rat Hypothalamus in vitro." Journal of neuroendocrinology vol. 2,2 (1990): 221-4. doi: https://doi.org/10.1111/j.1365-2826.1990.tb00854.x
Tsagarakis S, Rees LH, Besser GM, Grossman A. Gamma-Aminobutyric Acid Modulation of Corticotrophin-Releasing Factor-41 Secretion from the Rat Hypothalamus in vitro. J Neuroendocrinol. 1990 Apr 01;2(2):221-4. doi: 10.1111/j.1365-2826.1990.tb00854.x. PMID: 19210387.
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The identification of GABA receptor binding sites in insect ganglia.

Neurochemistry international

Lunt GG, Robinson TN, Miller T, Knowles WP, Olsen RW.
PMID: 20492983
Neurochem Int. 1985;7(5):751-4. doi: 10.1016/0197-0186(85)90028-2.

The binding of [(3)H]muscimol to membrane fractions from central nervous tissue from fly (Musca domestica) and locust (Schistocerca gregaria) was measured. Specific saturable binding was observed with K(d)s of 10 nM (locust) and 40 nM (fly) and B(max) values...

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Lunt GG, Robinson TN, Miller T, et al. The identification of GABA receptor binding sites in insect ganglia. Neurochem Int. 1985;7(5):751-4doi: 10.1016/0197-0186(85)90028-2.
Lunt, G. G., Robinson, T. N., Miller, T., Knowles, W. P., & Olsen, R. W. (1985). The identification of GABA receptor binding sites in insect ganglia. Neurochemistry international, 7(5), 751-4. https://doi.org/10.1016/0197-0186(85)90028-2
Lunt, G G, et al. "The identification of GABA receptor binding sites in insect ganglia." Neurochemistry international vol. 7,5 (1985): 751-4. doi: https://doi.org/10.1016/0197-0186(85)90028-2
Lunt GG, Robinson TN, Miller T, Knowles WP, Olsen RW. The identification of GABA receptor binding sites in insect ganglia. Neurochem Int. 1985;7(5):751-4. doi: 10.1016/0197-0186(85)90028-2. PMID: 20492983.
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Inactivation of medial prefrontal cortex impairs time interval discrimination in rats.

Frontiers in behavioral neuroscience

Kim J, Jung AH, Byun J, Jo S, Jung MW.
PMID: 19915730
Front Behav Neurosci. 2009 Nov 03;3:38. doi: 10.3389/neuro.08.038.2009. eCollection 2009.

Several lines of evidence suggest the involvement of prefrontal cortex in time interval estimation. The underlying neural processes are poorly understood, however, in part because of the paucity of physiological studies. The goal of this study was to establish...

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Kim J, Jung AH, Byun J, et al. Inactivation of medial prefrontal cortex impairs time interval discrimination in rats. Front Behav Neurosci. 2009;3:38doi: 10.3389/neuro.08.038.2009.
Kim, J., Jung, A. H., Byun, J., Jo, S., & Jung, M. W. (2009). Inactivation of medial prefrontal cortex impairs time interval discrimination in rats. Frontiers in behavioral neuroscience, 338. https://doi.org/10.3389/neuro.08.038.2009
Kim, Jieun, et al. "Inactivation of medial prefrontal cortex impairs time interval discrimination in rats." Frontiers in behavioral neuroscience vol. 3 (2009): 38. doi: https://doi.org/10.3389/neuro.08.038.2009
Kim J, Jung AH, Byun J, Jo S, Jung MW. Inactivation of medial prefrontal cortex impairs time interval discrimination in rats. Front Behav Neurosci. 2009 Nov 03;3:38. doi: 10.3389/neuro.08.038.2009. eCollection 2009. PMID: 19915730; PMCID: PMC2776483.
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The effect of various drug pretreatments on the convulsions and cerebellar cyclic nucleotide changes induced by the convulsant 4-isopropyl-2,6,7-trioxa-1-phosphatbicyclo(2,2,2)octane-1-oxide(IPTBO).

Neurochemistry international

Blenkinsop IS, Coult DB, Davies WE, Howells DJ.
PMID: 20488040
Neurochem Int. 1984;6(2):211-5. doi: 10.1016/0197-0186(84)90095-0.

The effects of pretreatment of mice with some drugs which modify GABAergic neurotransmission on the convulsions and cerebellar cyclic nucelotide level changes induced by the subsequent intracerebroventricular administration of 4-isopropyl-2,6,7-trioxa-1-phosphabicyclo(2,2,2)octane-1-oxide (IPTBO) have been studied. Muscimol, pentobarbitone and diazepam reduced...

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Blenkinsop IS, Coult DB, Davies WE, et al. The effect of various drug pretreatments on the convulsions and cerebellar cyclic nucleotide changes induced by the convulsant 4-isopropyl-2,6,7-trioxa-1-phosphatbicyclo(2,2,2)octane-1-oxide(IPTBO). Neurochem Int. 1984;6(2):211-5doi: 10.1016/0197-0186(84)90095-0.
Blenkinsop, I. S., Coult, D. B., Davies, W. E., & Howells, D. J. (1984). The effect of various drug pretreatments on the convulsions and cerebellar cyclic nucleotide changes induced by the convulsant 4-isopropyl-2,6,7-trioxa-1-phosphatbicyclo(2,2,2)octane-1-oxide(IPTBO). Neurochemistry international, 6(2), 211-5. https://doi.org/10.1016/0197-0186(84)90095-0
Blenkinsop, I S, et al. "The effect of various drug pretreatments on the convulsions and cerebellar cyclic nucleotide changes induced by the convulsant 4-isopropyl-2,6,7-trioxa-1-phosphatbicyclo(2,2,2)octane-1-oxide(IPTBO)." Neurochemistry international vol. 6,2 (1984): 211-5. doi: https://doi.org/10.1016/0197-0186(84)90095-0
Blenkinsop IS, Coult DB, Davies WE, Howells DJ. The effect of various drug pretreatments on the convulsions and cerebellar cyclic nucleotide changes induced by the convulsant 4-isopropyl-2,6,7-trioxa-1-phosphatbicyclo(2,2,2)octane-1-oxide(IPTBO). Neurochem Int. 1984;6(2):211-5. doi: 10.1016/0197-0186(84)90095-0. PMID: 20488040.
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Differential modulation by muscimol of [(3)H] flunitrazepam binding to benzodiazepine binding site subtypes.

Neurochemistry international

Mitchell R, Wilson L.
PMID: 20488060
Neurochem Int. 1984;6(3):387-92. doi: 10.1016/0197-0186(84)90082-2.

The effects of the GABA agonist, muscimol on [(3)H]flunitrazepam binding were examined in cerebellum and hippocampus regions proposed to contain different populations of benzodiazepine binding site subtypes. Quantitative analysis was made of the contribution of different components of [(3)H]flunitrazepam...

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Mitchell R, Wilson L. Differential modulation by muscimol of [(3)H] flunitrazepam binding to benzodiazepine binding site subtypes. Neurochem Int. 1984;6(3):387-92doi: 10.1016/0197-0186(84)90082-2.
Mitchell, R., & Wilson, L. (1984). Differential modulation by muscimol of [(3)H] flunitrazepam binding to benzodiazepine binding site subtypes. Neurochemistry international, 6(3), 387-92. https://doi.org/10.1016/0197-0186(84)90082-2
Mitchell, R, and Wilson, L. "Differential modulation by muscimol of [(3)H] flunitrazepam binding to benzodiazepine binding site subtypes." Neurochemistry international vol. 6,3 (1984): 387-92. doi: https://doi.org/10.1016/0197-0186(84)90082-2
Mitchell R, Wilson L. Differential modulation by muscimol of [(3)H] flunitrazepam binding to benzodiazepine binding site subtypes. Neurochem Int. 1984;6(3):387-92. doi: 10.1016/0197-0186(84)90082-2. PMID: 20488060.
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Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats.

Neurochemistry international

Goetz C, Bourgoin S, Cesselin F, Brandi A, Bression D, Martinet M, Peillon F, Hamon M.
PMID: 20487964
Neurochem Int. 1983;5(4):375-83. doi: 10.1016/0197-0186(83)90066-9.

The subcutaneous implantation of an estradiol pellet (10 mg) into female rats induced a hypophyseal hyperplasia with hyperprolactinaemia. Examination of neurotransmitter receptors in the hippocampus, striatum and cerebral cortex one month after the implantation revealed that estrogenization was associated...

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Goetz C, Bourgoin S, Cesselin F, et al. Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochem Int. 1983;5(4):375-83doi: 10.1016/0197-0186(83)90066-9.
Goetz, C., Bourgoin, S., Cesselin, F., Brandi, A., Bression, D., Martinet, M., Peillon, F., & Hamon, M. (1983). Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochemistry international, 5(4), 375-83. https://doi.org/10.1016/0197-0186(83)90066-9
Goetz, C, et al. "Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats." Neurochemistry international vol. 5,4 (1983): 375-83. doi: https://doi.org/10.1016/0197-0186(83)90066-9
Goetz C, Bourgoin S, Cesselin F, Brandi A, Bression D, Martinet M, Peillon F, Hamon M. Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochem Int. 1983;5(4):375-83. doi: 10.1016/0197-0186(83)90066-9. PMID: 20487964.
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The stimulation of GABA(B) receptors increases serotonin release in the rat suprachiasmatic area.

Neurochemistry international

François-Bellan AM, Hery M, Barrit MC, Faudon M, Hery F.
PMID: 20501142
Neurochem Int. 1987;11(1):55-62. doi: 10.1016/0197-0186(87)90148-3.

The action of ?-aminobutyric acid (GABA) and related compounds on the spontaneous release of newly synthesized [(3)H]5-hydroxytryptamine ([(3)H]5-HT) was studied in the suprachiasmatic area (SCA) using a superfusion system. GABA (10 ?M) increased [(3)H]5-HT release from SCA by up...

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François-Bellan AM, Hery M, Barrit MC, et al. The stimulation of GABA(B) receptors increases serotonin release in the rat suprachiasmatic area. Neurochem Int. 1987;11(1):55-62doi: 10.1016/0197-0186(87)90148-3.
François-Bellan, A. M., Hery, M., Barrit, M. C., Faudon, M., & Hery, F. (1987). The stimulation of GABA(B) receptors increases serotonin release in the rat suprachiasmatic area. Neurochemistry international, 11(1), 55-62. https://doi.org/10.1016/0197-0186(87)90148-3
François-Bellan, A M, et al. "The stimulation of GABA(B) receptors increases serotonin release in the rat suprachiasmatic area." Neurochemistry international vol. 11,1 (1987): 55-62. doi: https://doi.org/10.1016/0197-0186(87)90148-3
François-Bellan AM, Hery M, Barrit MC, Faudon M, Hery F. The stimulation of GABA(B) receptors increases serotonin release in the rat suprachiasmatic area. Neurochem Int. 1987;11(1):55-62. doi: 10.1016/0197-0186(87)90148-3. PMID: 20501142.
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Activation of hypothalamic gamma-aminobutyric Acid receptors resets the pendulum of the growth hormone clock.

Journal of neuroendocrinology

Willoughby JO, Kapoor R.
PMID: 19215359
J Neuroendocrinol. 1990 Jun 01;2(3):351-4. doi: 10.1111/j.1365-2826.1990.tb00417.x.

Abstract Plasma levels of growth hormone in male rats exhibit an ultradian rhythm having a periodicity of 3 to 4 h, bursts of growth hormone being separated by troughs when growth hormone secretion ceases. To determine if neurons in...

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Willoughby JO, Kapoor R. Activation of hypothalamic gamma-aminobutyric Acid receptors resets the pendulum of the growth hormone clock. J Neuroendocrinol. 1990;2(3):351-4doi: 10.1111/j.1365-2826.1990.tb00417.x.
Willoughby, J. O., & Kapoor, R. (1990). Activation of hypothalamic gamma-aminobutyric Acid receptors resets the pendulum of the growth hormone clock. Journal of neuroendocrinology, 2(3), 351-4. https://doi.org/10.1111/j.1365-2826.1990.tb00417.x
Willoughby, J O, and Kapoor, R. "Activation of hypothalamic gamma-aminobutyric Acid receptors resets the pendulum of the growth hormone clock." Journal of neuroendocrinology vol. 2,3 (1990): 351-4. doi: https://doi.org/10.1111/j.1365-2826.1990.tb00417.x
Willoughby JO, Kapoor R. Activation of hypothalamic gamma-aminobutyric Acid receptors resets the pendulum of the growth hormone clock. J Neuroendocrinol. 1990 Jun 01;2(3):351-4. doi: 10.1111/j.1365-2826.1990.tb00417.x. PMID: 19215359.
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The GABA(a) receptor complex in the developing chick optic tectum: Ontogeny of [(3)H]muscimol, [(3)H]flunitrazepam and [(35)S]TBPS binding sites.

Neurochemistry international

Batuecas A, Cubero A, Barat A, Ramírez G.
PMID: 20501190
Neurochem Int. 1987;11(4):425-31. doi: 10.1016/0197-0186(87)90032-5.

The developmental profiles of the neurotransmitter recognition site, labeled by [(3)H]muscimol, and of the two main modulatory sites, labeled by [(3)H]flunitrazepam and [ (35)S ]t- butylbicyclophosphorothionate , respectively, within the GABA(A) receptor complex, have been determined in chick tectal...

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Batuecas A, Cubero A, Barat A, et al. The GABA(a) receptor complex in the developing chick optic tectum: Ontogeny of [(3)H]muscimol, [(3)H]flunitrazepam and [(35)S]TBPS binding sites. Neurochem Int. 1987;11(4):425-31doi: 10.1016/0197-0186(87)90032-5.
Batuecas, A., Cubero, A., Barat, A., & Ramírez, G. (1987). The GABA(a) receptor complex in the developing chick optic tectum: Ontogeny of [(3)H]muscimol, [(3)H]flunitrazepam and [(35)S]TBPS binding sites. Neurochemistry international, 11(4), 425-31. https://doi.org/10.1016/0197-0186(87)90032-5
Batuecas, A, et al. "The GABA(a) receptor complex in the developing chick optic tectum: Ontogeny of [(3)H]muscimol, [(3)H]flunitrazepam and [(35)S]TBPS binding sites." Neurochemistry international vol. 11,4 (1987): 425-31. doi: https://doi.org/10.1016/0197-0186(87)90032-5
Batuecas A, Cubero A, Barat A, Ramírez G. The GABA(a) receptor complex in the developing chick optic tectum: Ontogeny of [(3)H]muscimol, [(3)H]flunitrazepam and [(35)S]TBPS binding sites. Neurochem Int. 1987;11(4):425-31. doi: 10.1016/0197-0186(87)90032-5. PMID: 20501190.
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Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals.

Frontiers in neuroengineering

Novellino A, Scelfo B, Palosaari T, Price A, Sobanski T, Shafer TJ, Johnstone AF, Gross GW, Gramowski A, Schroeder O, Jügelt K, Chiappalone M, Benfenati F, Martinoia S, Tedesco MT, Defranchi E, D'Angelo P, Whelan M.
PMID: 21562604
Front Neuroeng. 2011 Apr 27;4:4. doi: 10.3389/fneng.2011.00004. eCollection 2011.

Neuronal assemblies within the nervous system produce electrical activity that can be recorded in terms of action potential patterns. Such patterns provide a sensitive endpoint to detect effects of a variety of chemical and physical perturbations. They are a...

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Novellino A, Scelfo B, Palosaari T, et al. Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals. Front Neuroeng. 2011;4:4doi: 10.3389/fneng.2011.00004.
Novellino, A., Scelfo, B., Palosaari, T., Price, A., Sobanski, T., Shafer, T. J., Johnstone, A. F., Gross, G. W., Gramowski, A., Schroeder, O., Jügelt, K., Chiappalone, M., Benfenati, F., Martinoia, S., Tedesco, M. T., Defranchi, E., D'Angelo, P., & Whelan, M. (2011). Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals. Frontiers in neuroengineering, 44. https://doi.org/10.3389/fneng.2011.00004
Novellino, A, et al. "Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals." Frontiers in neuroengineering vol. 4 (2011): 4. doi: https://doi.org/10.3389/fneng.2011.00004
Novellino A, Scelfo B, Palosaari T, Price A, Sobanski T, Shafer TJ, Johnstone AF, Gross GW, Gramowski A, Schroeder O, Jügelt K, Chiappalone M, Benfenati F, Martinoia S, Tedesco MT, Defranchi E, D'Angelo P, Whelan M. Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals. Front Neuroeng. 2011 Apr 27;4:4. doi: 10.3389/fneng.2011.00004. eCollection 2011. PMID: 21562604; PMCID: PMC3087164.
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Intraocular injection of muscimol induces illusory motion reversal in goldfish.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Lee SY, Jung CS.
PMID: 20054494
Korean J Physiol Pharmacol. 2009 Dec;13(6):469-73. doi: 10.4196/kjpp.2009.13.6.469. Epub 2009 Dec 31.

Induced activation of the gamma-aminobutyric acid(A) (GABA(A)) receptor in the retina of goldfish caused the fish to rotate in the opposite direction to that of the spinning pattern during an optomotor response (OMR) measurement. Muscimol, a GABA(A) receptor agonist,...

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Lee SY, Jung CS. Intraocular injection of muscimol induces illusory motion reversal in goldfish. Korean J Physiol Pharmacol. 2009;13(6):469-73doi: 10.4196/kjpp.2009.13.6.469.
Lee, S. Y., & Jung, C. S. (2009). Intraocular injection of muscimol induces illusory motion reversal in goldfish. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 13(6), 469-73. https://doi.org/10.4196/kjpp.2009.13.6.469
Lee, Sang-Yoon, and Jung, Chang-Sub. "Intraocular injection of muscimol induces illusory motion reversal in goldfish." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 13,6 (2009): 469-73. doi: https://doi.org/10.4196/kjpp.2009.13.6.469
Lee SY, Jung CS. Intraocular injection of muscimol induces illusory motion reversal in goldfish. Korean J Physiol Pharmacol. 2009 Dec;13(6):469-73. doi: 10.4196/kjpp.2009.13.6.469. Epub 2009 Dec 31. PMID: 20054494; PMCID: PMC2802308.
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Showing 13 to 24 of 297 entries