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Showing 289 to 300 of 300 entries
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Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention.

Nature reviews. Cancer

Hecht SS, Hatsukami DK.
PMID: 34980891
Nat Rev Cancer. 2022 Jan 03; doi: 10.1038/s41568-021-00423-4. Epub 2022 Jan 03.

Tobacco products present a deadly combination of nicotine addiction and carcinogen exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless tobacco products lead to unacceptable exposure to multiple carcinogens, including the tobacco-specific nitrosamine N'-nitrosonornicotine,...

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Hecht SS, Hatsukami DK. Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nat Rev Cancer. 2022;doi: 10.1038/s41568-021-00423-4.
Hecht, S. S., & Hatsukami, D. K. (2022). Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nature reviews. Cancer, . https://doi.org/10.1038/s41568-021-00423-4
Hecht, Stephen S, and Hatsukami, Dorothy K. "Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention." Nature reviews. Cancer vol. (2022). doi: https://doi.org/10.1038/s41568-021-00423-4
Hecht SS, Hatsukami DK. Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nat Rev Cancer. 2022 Jan 03; doi: 10.1038/s41568-021-00423-4. Epub 2022 Jan 03. PMID: 34980891.
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Smokeless tobacco analysis: Simultaneous extraction and purification of alkaloids, volatile N-nitrosamines, and polycyclic hydrocarbons for GC-MS/MS.

Journal of separation science

Wang X, Qin Y, Nie C, Guo J, Pan L, Xie F, Wang S, Wang B, Zhao X, Wang B, Jia G.
PMID: 33915029
J Sep Sci. 2021 Jul;44(13):2642-2654. doi: 10.1002/jssc.202100186. Epub 2021 May 22.

Several smokeless tobacco products are available in the market and comprise complex chemical matrices. Sample preparation for analysis of the multiple classes of harmful compounds in smokeless tobacco products is highly cumbersome. In this study, a simultaneous extraction scheme...

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Wang X, Qin Y, Nie C, et al. Smokeless tobacco analysis: Simultaneous extraction and purification of alkaloids, volatile N-nitrosamines, and polycyclic hydrocarbons for GC-MS/MS. J Sep Sci. 2021;44(13):2642-2654doi: 10.1002/jssc.202100186.
Wang, X., Qin, Y., Nie, C., Guo, J., Pan, L., Xie, F., Wang, S., Wang, B., Zhao, X., Wang, B., & Jia, G. (2021). Smokeless tobacco analysis: Simultaneous extraction and purification of alkaloids, volatile N-nitrosamines, and polycyclic hydrocarbons for GC-MS/MS. Journal of separation science, 44(13), 2642-2654. https://doi.org/10.1002/jssc.202100186
Wang, Xiaoyu, et al. "Smokeless tobacco analysis: Simultaneous extraction and purification of alkaloids, volatile N-nitrosamines, and polycyclic hydrocarbons for GC-MS/MS." Journal of separation science vol. 44,13 (2021): 2642-2654. doi: https://doi.org/10.1002/jssc.202100186
Wang X, Qin Y, Nie C, Guo J, Pan L, Xie F, Wang S, Wang B, Zhao X, Wang B, Jia G. Smokeless tobacco analysis: Simultaneous extraction and purification of alkaloids, volatile N-nitrosamines, and polycyclic hydrocarbons for GC-MS/MS. J Sep Sci. 2021 Jul;44(13):2642-2654. doi: 10.1002/jssc.202100186. Epub 2021 May 22. PMID: 33915029.
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Chemical hazards in smoked meat and fish.

Food science & nutrition

Iko Afé OH, Kpoclou YE, Douny C, Anihouvi VB, Igout A, Mahillon J, Hounhouigan DJ, Scippo ML.
PMID: 34925818
Food Sci Nutr. 2021 Oct 18;9(12):6903-6922. doi: 10.1002/fsn3.2633. eCollection 2021 Dec.

This review aims to give an insight into the main hazards currently found in smoked meat and fish products. Literature research was carried out on international databases such as Access to Global Online Research in Agriculture (AGORA) database, Science...

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Iko Afé OH, Kpoclou YE, Douny C, et al. Chemical hazards in smoked meat and fish. Food Sci Nutr. 2021;9(12):6903-6922doi: 10.1002/fsn3.2633.
Iko Afé, O. H., Kpoclou, Y. E., Douny, C., Anihouvi, V. B., Igout, A., Mahillon, J., Hounhouigan, D. J., & Scippo, M. L. (2021). Chemical hazards in smoked meat and fish. Food science & nutrition, 9(12), 6903-6922. https://doi.org/10.1002/fsn3.2633
Iko Afé, Ogouyôm Herbert, et al. "Chemical hazards in smoked meat and fish." Food science & nutrition vol. 9,12 (2021): 6903-6922. doi: https://doi.org/10.1002/fsn3.2633
Iko Afé OH, Kpoclou YE, Douny C, Anihouvi VB, Igout A, Mahillon J, Hounhouigan DJ, Scippo ML. Chemical hazards in smoked meat and fish. Food Sci Nutr. 2021 Oct 18;9(12):6903-6922. doi: 10.1002/fsn3.2633. eCollection 2021 Dec. PMID: 34925818; PMCID: PMC8645718.
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An in vitro Study of Constituents Released From Smokeless Tobacco Products Into Human Saliva.

Journal of analytical toxicology

Guan S, Bush L, Ji H.
PMID: 34155520
J Anal Toxicol. 2021 Jun 22; doi: 10.1093/jat/bkab076. Epub 2021 Jun 22.

Smokeless tobacco (ST) products are used worldwide, and consumption is increasing in the United States. Although ST products are considered to occupy a different position on the tobacco product continuum of risk compared to combusted tobacco products, they can...

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Guan S, Bush L, Ji H. An in vitro Study of Constituents Released From Smokeless Tobacco Products Into Human Saliva. J Anal Toxicol. 2021;doi: 10.1093/jat/bkab076.
Guan, S., Bush, L., & Ji, H. (2021). An in vitro Study of Constituents Released From Smokeless Tobacco Products Into Human Saliva. Journal of analytical toxicology, . https://doi.org/10.1093/jat/bkab076
Guan, Siqi, et al. "An in vitro Study of Constituents Released From Smokeless Tobacco Products Into Human Saliva." Journal of analytical toxicology vol. (2021). doi: https://doi.org/10.1093/jat/bkab076
Guan S, Bush L, Ji H. An in vitro Study of Constituents Released From Smokeless Tobacco Products Into Human Saliva. J Anal Toxicol. 2021 Jun 22; doi: 10.1093/jat/bkab076. Epub 2021 Jun 22. PMID: 34155520.
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Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54.

Iranian journal of biotechnology

Jiang Y, Gong J, Chen Y, Hu B, Sun J, Zhu Y, Xia Z, Zou C.
PMID: 34825016
Iran J Biotechnol. 2021 Jul 01;19(3):e2812. doi: 10.30498/ijb.2021.240460.2812. eCollection 2021 Jul.

BACKGROUND: Microorganisms play an important role in reducing harmful substances in flue-cured tobacco. Numerous studies have been conducted to degrade nicotine by microorganisms.OBJECTIVES: The present research deals with the isolation of a potent bacterial strain able to efficiently degrade...

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Jiang Y, Gong J, Chen Y, et al. Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54. Iran J Biotechnol. 2021;19(3):e2812doi: 10.30498/ijb.2021.240460.2812.
Jiang, Y., Gong, J., Chen, Y., Hu, B., Sun, J., Zhu, Y., Xia, Z., & Zou, C. (2021). Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54. Iranian journal of biotechnology, 19(3), e2812. https://doi.org/10.30498/ijb.2021.240460.2812
Jiang, Yonglei, et al. "Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54." Iranian journal of biotechnology vol. 19,3 (2021): e2812. doi: https://doi.org/10.30498/ijb.2021.240460.2812
Jiang Y, Gong J, Chen Y, Hu B, Sun J, Zhu Y, Xia Z, Zou C. Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54. Iran J Biotechnol. 2021 Jul 01;19(3):e2812. doi: 10.30498/ijb.2021.240460.2812. eCollection 2021 Jul. PMID: 34825016; PMCID: PMC8590725.
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Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine.

Journal of cancer metastasis and treatment

Goyal N, Sridhar J, Do C, Bratton M, Shaik S, Jiang Q, Foroozesh M.
PMID: 34722929
J Cancer Metastasis Treat. 2021;7. doi: 10.20517/2394-4722.2020.143. Epub 2021 Apr 14.

AIM: In this study, our goal was to study the inhibition of nicotine metabolism by P450 2A6, as a means for reduction in tobacco use and consequently the prevention of smoking-related cancers. Nicotine, a phytochemical, is an addictive stimulant,...

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Goyal N, Sridhar J, Do C, et al. Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine. J Cancer Metastasis Treat. 2021;7doi: 10.20517/2394-4722.2020.143.
Goyal, N., Sridhar, J., Do, C., Bratton, M., Shaik, S., Jiang, Q., & Foroozesh, M. (2021). Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine. Journal of cancer metastasis and treatment, 7. https://doi.org/10.20517/2394-4722.2020.143
Goyal, Navneet, et al. "Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine." Journal of cancer metastasis and treatment vol. 7 (2021). doi: https://doi.org/10.20517/2394-4722.2020.143
Goyal N, Sridhar J, Do C, Bratton M, Shaik S, Jiang Q, Foroozesh M. Identification of CYP 2A6 inhibitors in an effort to mitigate the harmful effects of the phytochemical nicotine. J Cancer Metastasis Treat. 2021;7. doi: 10.20517/2394-4722.2020.143. Epub 2021 Apr 14. PMID: 34722929; PMCID: PMC8555909.
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Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis.

Nitric oxide : biology and chemistry

SeyyedSalehi MS, Mohebbi E, Sasanfar B, Toorang F, Zendehdel K.
PMID: 34119660
Nitric Oxide. 2021 Oct 01;115:1-7. doi: 10.1016/j.niox.2021.06.003. Epub 2021 Jun 10.

Bladder cancer is the most common cancer of the urinary tract. While tobacco smoking is responsible for more than half of the bladder cancer cases, occupational exposures is also an established risk factor of bladder cancer. Strong evidence of...

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SeyyedSalehi MS, Mohebbi E, Sasanfar B, et al. Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis. Nitric Oxide. 2021;115:1-7doi: 10.1016/j.niox.2021.06.003.
SeyyedSalehi, M. S., Mohebbi, E., Sasanfar, B., Toorang, F., & Zendehdel, K. (2021). Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis. Nitric oxide : biology and chemistry, 1151-7. https://doi.org/10.1016/j.niox.2021.06.003
SeyyedSalehi, Monireh Sadat, et al. "Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis." Nitric oxide : biology and chemistry vol. 115 (2021): 1-7. doi: https://doi.org/10.1016/j.niox.2021.06.003
SeyyedSalehi MS, Mohebbi E, Sasanfar B, Toorang F, Zendehdel K. Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis. Nitric Oxide. 2021 Oct 01;115:1-7. doi: 10.1016/j.niox.2021.06.003. Epub 2021 Jun 10. PMID: 34119660.
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Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water.

Environmental research

Zhao C, Zhang H, Zhou J, Lu Q, Zhang Y, Yu X, Wang S, Liu R, Pu Y, Yin L.
PMID: 34506781
Environ Res. 2022 Mar;204:111997. doi: 10.1016/j.envres.2021.111997. Epub 2021 Sep 07.

Nitrosamines, a group of emerging nitrogenous pollutants, are ubiquitously found in the drinking water system. However, less is known about how systemic biological responses resist or tolerate nitrosamines, especially long-term co-exposure at low concentrations. In this study, untargeted metabolomics...

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Zhao C, Zhang H, Zhou J, et al. Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environ Res. 2021;204:111997doi: 10.1016/j.envres.2021.111997.
Zhao, C., Zhang, H., Zhou, J., Lu, Q., Zhang, Y., Yu, X., Wang, S., Liu, R., Pu, Y., & Yin, L. (2022). Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environmental research, 204111997. https://doi.org/10.1016/j.envres.2021.111997
Zhao, Chao, et al. "Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water." Environmental research vol. 204 (2022): 111997. doi: https://doi.org/10.1016/j.envres.2021.111997
Zhao C, Zhang H, Zhou J, Lu Q, Zhang Y, Yu X, Wang S, Liu R, Pu Y, Yin L. Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environ Res. 2022 Mar;204:111997. doi: 10.1016/j.envres.2021.111997. Epub 2021 Sep 07. PMID: 34506781.
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Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure.

Environmental pollution (Barking, Essex : 1987)

Zhang H, Zhao C, Liu Q, Zhang Y, Luo K, Pu Y, Yin L.
PMID: 34915095
Environ Pollut. 2021 Dec 13;297:118680. doi: 10.1016/j.envpol.2021.118680. Epub 2021 Dec 13.

Nitrosamines, as ubiquitous environmental carcinogens with adverse impact on human health, were crucial inducers of esophageal cancer (EC). Esophageal inflammation (EI) was an important biological process and considered to be associated with the progression of EC. However, the underlying...

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Zhang H, Zhao C, Liu Q, et al. Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure. Environ Pollut. 2021;297:118680doi: 10.1016/j.envpol.2021.118680.
Zhang, H., Zhao, C., Liu, Q., Zhang, Y., Luo, K., Pu, Y., & Yin, L. (2021). Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure. Environmental pollution (Barking, Essex : 1987), 297118680. https://doi.org/10.1016/j.envpol.2021.118680
Zhang, Hu, et al. "Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure." Environmental pollution (Barking, Essex : 1987) vol. 297 (2021): 118680. doi: https://doi.org/10.1016/j.envpol.2021.118680
Zhang H, Zhao C, Liu Q, Zhang Y, Luo K, Pu Y, Yin L. Dysregulation of fatty acid metabolism associated with esophageal inflammation of ICR mice induced by nitrosamines exposure. Environ Pollut. 2021 Dec 13;297:118680. doi: 10.1016/j.envpol.2021.118680. Epub 2021 Dec 13. PMID: 34915095.
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Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats.

Journal of biochemical and molecular toxicology

Adeleke GE, Adaramoye OA.
PMID: 34472159
J Biochem Mol Toxicol. 2021 Nov;35(11):e22901. doi: 10.1002/jbt.22901. Epub 2021 Sep 02.

N-nitrosamines have been linked with cancer in humans due to their presence in drinking water and diets. This study evaluated the role of betulinic acid (BA) in abating oxidative stress, inflammation, and hyperlipidemia in rats treated with N-nitrosodimethylamine (NDMA)....

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Adeleke GE, Adaramoye OA. Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats. J Biochem Mol Toxicol. 2021;35(11):e22901doi: 10.1002/jbt.22901.
Adeleke, G. E., & Adaramoye, O. A. (2021). Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats. Journal of biochemical and molecular toxicology, 35(11), e22901. https://doi.org/10.1002/jbt.22901
Adeleke, Gbadebo E, and Adaramoye, Oluwatosin A. "Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats." Journal of biochemical and molecular toxicology vol. 35,11 (2021): e22901. doi: https://doi.org/10.1002/jbt.22901
Adeleke GE, Adaramoye OA. Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats. J Biochem Mol Toxicol. 2021 Nov;35(11):e22901. doi: 10.1002/jbt.22901. Epub 2021 Sep 02. PMID: 34472159.
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Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water.

Environmental research

Zhao C, Zhang H, Zhou J, Lu Q, Zhang Y, Yu X, Wang S, Liu R, Pu Y, Yin L.
PMID: 34506781
Environ Res. 2021 Sep 07;204:111997. doi: 10.1016/j.envres.2021.111997. Epub 2021 Sep 07.

Nitrosamines, a group of emerging nitrogenous pollutants, are ubiquitously found in the drinking water system. However, less is known about how systemic biological responses resist or tolerate nitrosamines, especially long-term co-exposure at low concentrations. In this study, untargeted metabolomics...

Cite
Zhao C, Zhang H, Zhou J, et al. Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environ Res. 2021;204:111997doi: 10.1016/j.envres.2021.111997.
Zhao, C., Zhang, H., Zhou, J., Lu, Q., Zhang, Y., Yu, X., Wang, S., Liu, R., Pu, Y., & Yin, L. (2021). Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environmental research, 204111997. https://doi.org/10.1016/j.envres.2021.111997
Zhao, Chao, et al. "Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water." Environmental research vol. 204 (2021): 111997. doi: https://doi.org/10.1016/j.envres.2021.111997
Zhao C, Zhang H, Zhou J, Lu Q, Zhang Y, Yu X, Wang S, Liu R, Pu Y, Yin L. Metabolomics-based molecular signatures reveal the toxic effect of co-exposure to nitrosamines in drinking water. Environ Res. 2021 Sep 07;204:111997. doi: 10.1016/j.envres.2021.111997. Epub 2021 Sep 07. PMID: 34506781.
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High level nitrosamines in rat faeces with colorectal cancer determined by a sensitive GC-MS method.

Journal of pharmaceutical and biomedical analysis

Zhao ZX, Chen SZ, Xia ZL, Bin Xu Y, Zhang LL, Tian SM, Fan Q.
PMID: 34998074
J Pharm Biomed Anal. 2022 Jan 03;210:114576. doi: 10.1016/j.jpba.2021.114576. Epub 2022 Jan 03.

N-nitrosamines (NAs) are common toxic substances that have a strong correlation with many human diseases, such as liver damage and cancer. However, there is a lack of studies on methods involving the detection of NAs in biological samples, possibly...

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Zhao ZX, Chen SZ, Xia ZL, et al. High level nitrosamines in rat faeces with colorectal cancer determined by a sensitive GC-MS method. J Pharm Biomed Anal. 2022;210:114576doi: 10.1016/j.jpba.2021.114576.
Zhao, Z. X., Chen, S. Z., Xia, Z. L., Bin Xu, Y., Zhang, L. L., Tian, S. M., & Fan, Q. (2022). High level nitrosamines in rat faeces with colorectal cancer determined by a sensitive GC-MS method. Journal of pharmaceutical and biomedical analysis, 210114576. https://doi.org/10.1016/j.jpba.2021.114576
Zhao, Zhen Xiong, et al. "High level nitrosamines in rat faeces with colorectal cancer determined by a sensitive GC-MS method." Journal of pharmaceutical and biomedical analysis vol. 210 (2022): 114576. doi: https://doi.org/10.1016/j.jpba.2021.114576
Zhao ZX, Chen SZ, Xia ZL, Bin Xu Y, Zhang LL, Tian SM, Fan Q. High level nitrosamines in rat faeces with colorectal cancer determined by a sensitive GC-MS method. J Pharm Biomed Anal. 2022 Jan 03;210:114576. doi: 10.1016/j.jpba.2021.114576. Epub 2022 Jan 03. PMID: 34998074.
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