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Showing 25 to 36 of 300 entries
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Fabrication of 8-aminocaprylic acid doped UIO-66 as sensitive solid-phase microextraction fiber for nitrosamines.

Talanta

Huang Z, Liu S, Xu J, Yin L, Sun F, Zhou N, Ouyang G.
PMID: 29136873
Talanta. 2018 Feb 01;178:629-635. doi: 10.1016/j.talanta.2017.09.090. Epub 2017 Oct 01.

The introduction of functional groups into metal organic frameworks has great potential for enhancement in adsorption performance of nitrosamines using solid phase microextraction (SPME). However, pre-functionalization and post-modification generally suffer from the same limitation that the additional functional groups...

Molecular characterization of neuroendocrine lung-tumors induced in hamsters by treatment with nitrosamines and hyperoxia.

International journal of oncology

Miller M, Baxter J, Moore J, Lewis J, Schuller H.
PMID: 21566881
Int J Oncol. 1994 Jan;4(1):5-12. doi: 10.3892/ijo.4.1.5.

Treatment of hamsters with nitrosamines and hyperoxia (60% O2) induces neuroendocrine lung tumors. Analysis of 8 different tumors from 7 different hamsters demonstrated 2- to 3.5-fold increases in the expression of c-myc in 4 of 8 tumors, c-fos in...

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke.

Toxics

Ma B, Stepanov I, Hecht SS.
PMID: 30893918
Toxics. 2019 Mar 19;7(1). doi: 10.3390/toxics7010016.

DNA adducts are believed to play a central role in the induction of cancer in cigarette smokers and are proposed as being potential biomarkers of cancer risk. We have summarized research conducted since 2012 on DNA adduct formation in...

Smokeless Tobacco and Its Adverse Effects on Hematological Parameters: A Cross-Sectional Study.

Advances in preventive medicine

Shukla AK, Khaitan T, Gupta P, Naik SR.
PMID: 31057975
Adv Prev Med. 2019 Apr 01;2019:3182946. doi: 10.1155/2019/3182946. eCollection 2019.

BACKGROUND: Smokeless tobacco (SLT) as a drug substance has been used throughout the world although it has dangerous effects on human health. Among the 28 known carcinogens in SLT, tobacco-specific nitrosamines are considered to be the most potent. This...

Experimental and DFT Computational Insight into Nitrosamine Photochemistry-Oxygen Matters.

The journal of physical chemistry. A

Ghogare AA, Debaz CJ, Silva Oliveira M, Abramova I, Mohapatra PP, Kwon K, Greer EM, Prado FM, Valerio HP, Di Mascio P, Greer A.
PMID: 28707899
J Phys Chem A. 2017 Aug 17;121(32):5954-5966. doi: 10.1021/acs.jpca.7b02414. Epub 2017 Aug 02.

A nitrosamine photooxidation reaction is shown to generate a peroxy intermediate by experimental physical-organic methods. The irradiation of phenyl and methyl-substituted nitrosamines in the presence of isotopically labeled 18-oxygen revealed that an O atom was trapped from a peroxy...

Variability of TSNA in U.S. Tobacco and Moist Smokeless Tobacco Products.

Toxicology reports

Oldham MJ, Lion KE, Phillips DJ, Morton MJ, Lusso MF, Harris EA, Jordan JL, Franke JE, Strickland JA.
PMID: 32612935
Toxicol Rep. 2020 Jun 13;7:752-758. doi: 10.1016/j.toxrep.2020.05.008. eCollection 2020.

Tobacco-specific nitrosamines (TSNAs) have been of concern to the public health community for decades and their reduction through agricultural practices, plant breeding, and tobacco processing has also been a decades-long industry effort. Despite those efforts, TSNAs, though lower, continue...

Application of chromatographic techniques in the analysis of total nitrosamines in water.

Heliyon

Yahaya A, Babatunde D, Olaniyan LWB, Agboola O.
PMID: 32154411
Heliyon. 2020 Mar 03;6(3):e03447. doi: 10.1016/j.heliyon.2020.e03447. eCollection 2020 Mar.

The use of ozone, chloramine and chlorine dioxide for water treatment results in the formation N-nitrosamines in the treated water. These groups of chemicals and other nitrogen-containing compounds have been described as disinfection by-products (DBPs) which are known for...

Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring's Health Outcome.

Toxics

Li G, Saad S, Oliver BG, Chen H.
PMID: 30071638
Toxics. 2018 Aug 01;6(3). doi: 10.3390/toxics6030043.

Maternal smoking during pregnancy leads to gestational complications and organ disorders in the offspring. As nicotine replacement therapy is often ineffective for smoking cessation, pregnant women turn to alternatives such as heat-not-burn tobacco and e-cigarettes. Recently, the popularly of...

Reagent-free and pH-independent degradation of N-nitrosamines using electrons generated via corona discharge at ambient pressure.

Journal of mass spectrometry : JMS

Zhuang M, Li H, Jiang J, Huang G.
PMID: 30536522
J Mass Spectrom. 2019 Feb;54(2):141-147. doi: 10.1002/jms.4318.

Traditional degradation methods for N-nitrosamines are either confined with acid solution or required for additional chemical reagents to guarantee high reaction efficiency. Herein, we demonstrate a facile and effective way for reagent-free and pH-independent degradation of N-nitrosamines, which was...

Impacts of texture properties and airborne particles on accumulation of tobacco-derived chemicals in fabrics.

Journal of hazardous materials

Wu CC, Wang WJ, Bao LJ, Shi L, Tao S, Zeng EY.
PMID: 30776593
J Hazard Mater. 2019 May 05;369:108-115. doi: 10.1016/j.jhazmat.2018.12.107. Epub 2019 Feb 10.

Vapor-phase constituents of tobacco smoke are known to accumulate on clothing surfaces; however, the significance of texture properties, such as specific surface area, porosity, and surface roughness, and airborne particles to the sorption capacity of fabrics has not been...

Controlling the primary particle evolution process towards silica monoliths with tunable hierarchical structure.

Journal of colloid and interface science

Zhou Y, Lin WG, Yang J, Gao L, Lin N, Yang JY, Hou Q, Wang Y, Zhu JH.
PMID: 21943511
J Colloid Interface Sci. 2011 Dec 15;364(2):594-604. doi: 10.1016/j.jcis.2011.08.061. Epub 2011 Aug 31.

In order to establish the hierarchical structure in multiple levels on mesoporous silica, this article reports a new strategy to prepare the monolith with the pore configuration in nanometer scale, micro-morphology in micrometer level and macroscopic shape in millimeter...

Constitutive activation of nitrate reductase in tobacco alters flowering time and plant biomass.

Scientific reports

Lu J, Chandrakanth NN, Lewis RS, Andres K, Bovet L, Goepfert S, Dewey RE.
PMID: 33608646
Sci Rep. 2021 Feb 19;11(1):4222. doi: 10.1038/s41598-021-83797-7.

Pyridine alkaloids produced in tobacco can react with nitrosating agents such as nitrite to form tobacco-specific nitrosamines (TSNA), which are among the most notable toxicants present in tobacco smoke. The market type known as burley tobacco is particularly susceptible...

Showing 25 to 36 of 300 entries