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Showing 25 to 36 of 482 entries
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Investigation on sensitized chemiluminescence systems and their mechanism for five fluoroquinolones.

Analytica chimica acta

Sun H, Li L, Chen X.
PMID: 17723632
Anal Chim Acta. 2006 Aug 25;576(2):192-9. doi: 10.1016/j.aca.2006.06.013. Epub 2006 Jun 16.

The novel chemiluminescence (CL) reaction systems were established for lomefloxacin (LMFX), ofloxacin(OFLX), norfloxacin (NFLX), gatifloxacin (GAFX) and enoxacin (ENX). The sensitized CL emission mechanism was investigated for the five systems by comparing the fluorescence emission with CL spectra. For...

Quinolone pharmacokinetics.

International journal of antimicrobial agents

Robson RA.
PMID: 18611512
Int J Antimicrob Agents. 1992 Dec;2(1):3-10. doi: 10.1016/0924-8579(92)90020-r.

Fluoroquinolones have broad antibacterial spectra and are active against most Gram-negative and many Gram-positive species. They exhibit excellent oral bioavailability, extensive tissue penetration, low protein binding, and a long elimination half-life. This review compares and contrasts the pharmakonetics of...

Ofloxacin induced leucopenia in complicated falciparum malaria: a case report.

Cases journal

Tripathy S, Adhya A.
PMID: 19829908
Cases J. 2009 Jun 09;2:7097. doi: 10.4076/1757-1626-2-7097.

INTRODUCTION: To report a case of ofloxacin-associated leucopoenia, which occurred in a patient of falciparum malaria shortly after administration and resolved following discontinuation of the drug.CASE PRESENTATION: A 44 year old female was admitted in circulatory shock with a...

Targeting Multidrug Resistant Mycobacterium tuberculosis HtrA2 with Identical Chemical Entities of Fluoroquinolones.

Indian journal of pharmaceutical sciences

Daisy P, Vijayalakshmi P, Selvaraj C, Singh SK, Saipriya K.
PMID: 23440996
Indian J Pharm Sci. 2012 May;74(3):217-22. doi: 10.4103/0250-474X.106063.

Tuberculosis is a highly communicable and chronic respiratory disease caused by pathogenic bacterium Mycobacterium tuberculosis. The drug - resistant species of Mycobacterium tuberculosis are tough to cure due to its resistant activity toward potential drugs. Available inhibitors of tuberculosis...

In vitro evaluation of microbiological flora of orofacial infections.

Journal of maxillofacial and oral surgery

Kohli M, Mathur A, Kohli M, Siddiqui SR.
PMID: 23139538
J Maxillofac Oral Surg. 2009 Dec;8(4):329-33. doi: 10.1007/s12663-009-0080-1. Epub 2010 Apr 24.

OBJECTIVE: To assess the most common micro-organisms causing odontogenic infections and their antimicrobial susceptibility.METHODS: The study was conducted in 80 patients with orofacial infection. The pus sample was collected, cultured (aerobically and anaerobically) and stained for morphological study of...

Patterns of antimicrobial resistance in the causative organisms of spontaneous bacterial peritonitis: a single centre, six-year experience of 1981 samples.

International journal of hepatology

Sheikhbahaei S, Abdollahi A, Hafezi-Nejad N, Zare E.
PMID: 24778884
Int J Hepatol. 2014;2014:917856. doi: 10.1155/2014/917856. Epub 2014 Mar 20.

Background/Aims. Spontaneous bacterial peritonitis (SBP) is one of the leading causes of morbidity and mortality in patients with cirrhosis. This study aims to determine the microbial agents of SBP and the pattern of antibiotic resistance, in a large number...

Design and development of novel dual-compartment capsule for improved gastroretention.

ISRN pharmaceutics

Patil GB, Singh SS, Ramani KP, Chatap VK, Deshmukh PK.
PMID: 23431476
ISRN Pharm. 2013;2013:752471. doi: 10.1155/2013/752471. Epub 2013 Jan 27.

The aim of the proposed research work was to develop a novel dual-compartment capsule (NDCC) with polymeric disc for gastroretentive dosage form, which will ultimately result in better solubility and bioavailability of Ofloxacin. Floating ring caps were formulated by...

Rapid diagnosis of acanthamoeba keratitis using non-nutrient agar with a lawn of E. coli.

Journal of ophthalmic inflammation and infection

Borin S, Feldman I, Ken-Dror S, Briscoe D.
PMID: 23514313
J Ophthalmic Inflamm Infect. 2013 Feb 27;3(1):40. doi: 10.1186/1869-5760-3-40.

BACKGROUND: A patient presented with a corneal foreign body in his only eye. He was treated with prophylactic antibiotics and sent home, but deteriorated.FINDINGS: He returned to the hospital 5 days later, and on slit-lamp examination, there was ciliary...

Ofloxacin-induced toxic epidermal necrolysis.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Gupta G.
PMID: 25136199
Indian J Crit Care Med. 2014 Aug;18(8):545-6. doi: 10.4103/0972-5229.138166.

No abstract available.

Pyrazinamide-induced exfoliative dermatitis in a patient on hemodialysis: a rare complication.

Case reports in nephrology

Jaisuresh K.
PMID: 24527247
Case Rep Nephrol. 2013;2013:387293. doi: 10.1155/2013/387293. Epub 2013 Sep 18.

A 60-year-old male patient on maintenance hemodialysis was started on antituberculosis therapy with isoniazid, rifampin, ethambutol, and pyrazinamide for pulmonary tuberculosis. After 4 weeks of therapy, he developed pruritic lesions in the extremities followed by exfoliation. The lesions progressively...

Unusual presentation of phacolytic glaucoma: simulating microbial keratitis.

Case reports in ophthalmological medicine

Sahu SK, Keswarwani S, Mittal R.
PMID: 22606478
Case Rep Ophthalmol Med. 2011;2011:850919. doi: 10.1155/2011/850919. Epub 2011 Dec 20.

The differential diagnoses for phacolytic glaucoma are acute angle closure glaucoma, open angle glaucoma with uveitis, neovascular glaucoma, and glaucoma secondary to trauma. We report an unusual case where the dislocated cataractous lens firmly adherent to the corneal endothelium...

Chapter 6 ofloxacin.

Profiles of drug substances, excipients, and related methodology

Al-Omar MA.
PMID: 22469176
Profiles Drug Subst Excip Relat Methodol. 2009;34:265-98. doi: 10.1016/S1871-5125(09)34006-6. Epub 2010 Mar 16.

No abstract available.

Showing 25 to 36 of 482 entries