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Showing 61 to 62 of 62 entries
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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.

Nature communications

Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, Papachristoforou E, Argemi J, Mendes BG, Wang Y, Su H, Sun W, Llorente C, Hendrikx T, Liu X, Hosseini M, Kisseleva T, Brenner DA, Bataller R, Ramachandran P, Karin M, Fu W, Schnabl B.
PMID: 34887405
Nat Commun. 2021 Dec 09;12(1):7172. doi: 10.1038/s41467-021-27385-3.

Complement receptor of immunoglobulin superfamily (CRIg) is expressed on liver macrophages and directly binds complement component C3b or Gram-positive bacteria to mediate phagocytosis. CRIg plays important roles in several immune-mediated diseases, but it is not clear how its pathogen...

A Perspective Of Intestinal Immune-Microbiome Interactions In Alcohol-Associated Liver Disease.

International journal of biological sciences

Bruellman R, Llorente C.
PMID: 33390852
Int J Biol Sci. 2021 Jan 01;17(1):307-327. doi: 10.7150/ijbs.53589. eCollection 2021.

Uncovering the intricacies of the gut microbiome and how it interacts with the host immune system has opened up pathways in the search for the treatment of disease conditions. Alcohol-associated liver disease is a major cause of death worldwide....

Showing 61 to 62 of 62 entries