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Showing 25 to 36 of 73 entries
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Therapeutic Treatment with Abdominal Adipose Mesenchymal Cells Does Not Prevent Elastase-Induced Emphysema in Rats.

Turkish thoracic journal

Gülhan PY, Ekici MS, Niyaz M, Gülhan M, Erçin ME, Ekici A, Aksoy N.
PMID: 32163359
Turk Thorac J. 2020 Jan;21(1):14-20. doi: 10.5152/TurkThoracJ.2019.180136. Epub 2020 Jan 01.

OBJECTIVES: Emphysema and chronic bronchitis have different pathophysiologies but both are significant components of chronic obstructive lung disease (COPD). The levels of Matrix metalloproteinase (MMP)-9 in the bronchoalveloar lavage fluid (BALF) and in serum indicate the presence of emphysema....

Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression.

Journal of the American Heart Association

Gäbel G, Northoff BH, Balboa A, Becirovic-Agic M, Petri M, Busch A, Maegdefessel L, Mahlmann A, Ludwig S, Teupser D, de Waard V, Golledge J, Wanhainen A, Wågsäter D, Holdt LM, Lindeman JHN.
PMID: 34420357
J Am Heart Assoc. 2021 Sep 07;10(17):e020231. doi: 10.1161/JAHA.120.020231. Epub 2021 Aug 21.

Background While numerous interventions effectively interfered with abdominal aortic aneurysm (AAA) formation/progression in preclinical models, none of the successes translated into clinical success. Hence, a systematic exploration of parallel and divergent processes in clinical AAA disease and its 2...

Radiofrequency therapy improves exercise capacity of mice with emphysema.

Scientific reports

Tsutsui M, Cheung CY, Wada T, Jaw JE, Yang CWT, Bernatchez P, White Z, Yang CX, Bae EJA, Choi LH, Gelbart D, Lichtenstein S, Machan L, Elizur E, Wolff K, Goodacre E, Lipnicki M, Wong D, Sin DD.
PMID: 34625605
Sci Rep. 2021 Oct 08;11(1):20056. doi: 10.1038/s41598-021-99474-8.

Emphysema is a common phenotype of chronic obstructive pulmonary disease (COPD). Although resection of emphysematous tissue can improve lung mechanics, it is invasive and fraught with adverse effects. Meanwhile, radiofrequency (RF) treatment is an extracorporeal method that leads to...

Molecular elucidation of pancreatic elastase inhibition by baicalein.

Journal of biomolecular structure & dynamics

Ghosh D, Bansode S, Joshi R, Kolte B, Gacche R.
PMID: 33446085
J Biomol Struct Dyn. 2021 Jan 15;1-10. doi: 10.1080/07391102.2021.1873189. Epub 2021 Jan 15.

The serine protease, elastase exists in various forms and plays diverse roles in the human body. Pharmacological inhibition of elastase has been investigated for its therapeutic role in managing conditions such as diabetes, pneumonia and arthritis. Sivelestat, a synthetic...

Gut proteases target Yersinia invasin in vivo.

BMC research notes

Trček J, Oellerich MF, Niedung K, Ebel F, Freund S, Trülzsch K.
PMID: 21501502
BMC Res Notes. 2011 Apr 18;4:129. doi: 10.1186/1756-0500-4-129.

BACKGROUND: Yersinia enterocolitica is a common cause of food borne gastrointestinal disease. After oral uptake, yersiniae invade Peyer's patches of the distal ileum. This is accomplished by the binding of the Yersinia invasin to β1 integrins on the apical...

Associations with pancreatic exocrine insufficiency: An United Kingdom single-centre study.

World journal of clinical cases

Shandro BM, Chen J, Ritehnia J, Poullis A.
PMID: 34877281
World J Clin Cases. 2021 Nov 06;9(31):9469-9480. doi: 10.12998/wjcc.v9.i31.9469.

BACKGROUND: Pancreatic exocrine insufficiency (PEI) is said to be associated with numerous conditions both within and outside the gastrointestinal (GI) system. The majority of research has been concerned with conditions that reduce the volume of functioning pancreatic tissue or...

The effects of areca catechu L extract on anti-aging.

International journal of cosmetic science

Lee KK, Choi JD.
PMID: 18503446
Int J Cosmet Sci. 1999 Aug;21(4):285-95. doi: 10.1046/j.1467-2494.1999.196563.x.

The anti-aging effects of Areca catechu L extract (CC-516) on skin were investigate both in vitro and in vivo. The CC-516 has a high proportion of proline (13%) of free amino acid content. The inhibitory effect of CC-516 on...

Study of the refirming effect of a plant complex.

International journal of cosmetic science

Benaiges A, Marcet P, Armengol R, Betes C, Gironés E.
PMID: 18505506
Int J Cosmet Sci. 1998 Aug;20(4):223-33. doi: 10.1046/j.1467-2494.1998.176608.x.

Loss of skin elasticity is one of the main problems of ageing. This is a mechanical property influenced by elastin, a protein in the dermis which, together with collagen and glycosaminoglycans, makes up the connective tissue. This tissue is...

Synthesis and Localization of Pancreatic Secretory Proteins in Pancreatic Acinar-like Metaplasia in the Distal Part of the Oesophagus.

Scandinavian journal of gastroenterology

Håkansson HO, Mellblom L, Johansson J, Bjartell A, Borgström A.
PMID: 27897096
Scand J Gastroenterol. 2003 Jan;38(1):10-13. doi: 10.1080/00365521.2003.11800650.

BACKGROUND: Pancreatic acinar-like metaplasia has previously been described in the gastric mucosa and in the distal part of the oesophagus. The resemblance to pancreatic acinar cells prompted us to study the possible occurrence of secretory pancreatic proteins in these...

Development of a Model for Abdominal Aortic Aneurysms in Swine.

The Journal of surgical research

De Leo N, Melillo A, Zhang P, Badach J, Miller H, Lin A, Williamson J, Ghobrial G, Gaughan J, Krishnadoss V, Noshadi I, Brown SA, Carpenter JP.
PMID: 34289418
J Surg Res. 2021 Dec;268:79-86. doi: 10.1016/j.jss.2021.05.047. Epub 2021 Jul 18.

INTRODUCTION: Producing a reliable large-animal model of AAA has proven challenging. We sought to create a reproducible swine model of AAA using enzymatic degradation of the aortic wall.METHODS: Twelve male Yorkshire swine received periadventitial injections of type 1 collagenase...

Frequency of abnormal fecal biomarkers in irritable bowel syndrome.

Global advances in health and medicine

Goepp J, Fowler E, McBride T, Landis D.
PMID: 24891989
Glob Adv Health Med. 2014 May;3(3):9-15. doi: 10.7453/gahmj.2013.099.

PRIMARY STUDY OBJECTIVE: Determine the frequency of abnormal fecal biomarker test results in patients with 13 irritable bowel syndrome (IBS)-related ICD-9 (International Statistical Classification of Diseases and Related Health Problems) codes.STUDY DESIGN: Quantitative review of de-identified records from patients...

Effect of chromogranin A N-terminal fragment vasostatin-1 nano-carrier transfection on abdominal aortic aneurysm formation.

Bioengineered

Wang P, Wang W, Peng X, Ruan F, Yang S.
PMID: 34839793
Bioengineered. 2021 Dec;12(2):11018-11029. doi: 10.1080/21655979.2021.2005222.

The effects of transfection of N-terminal fragment of chromogranin A Vasostatin-1 (VS-1) nanocarriers on formation of abdominal aortic aneurysm (AAA) were discussed, and its mechanism was analyzed. Nanoparticles containing VS-1 genes were prepared by emulsion solvent evaporation method, and...

Showing 25 to 36 of 73 entries