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Showing 13 to 24 of 395 entries
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Pentobarbital discrimination and generalization to other drugs under multiple fixed-ratio fixed-interval schedules.

Behavioural pharmacology

McMillan DE, Hardwick WC.
PMID: 11224420
Behav Pharmacol. 1996 May;7(3):285-293.

Pigeons were trained to discriminate 5mg/kg pentobarbital from saline under several multiple fixed-ratio fixed-interval schedules of food presentation. The following schedules were studied: multiple fixed-ratio 40 fixed-interval 18s (mult FR40 FI18), mult FR10 FI18s, mult FR10 FI180s and mult...

Discriminative-stimulus control by morphine in the pigeon under a fixed-interval schedule of reinforcement.

Behavioural pharmacology

Massey BW, McMillan DE, Wessinger WD.
PMID: 11224150
Behav Pharmacol. 1992 Oct;3(5):475-488.

The stimulus control by morphine under a fixed-interval (FI) 180-s schedule of reinforcement was examined in five pigeons trained to discriminate 5.0mg/kg of i.m. morphine from saline. After training, dose-response relationships were determined for morphine, d-amphetamine, pentobarbital, fentanyl, and...

[Techniques in experimental surgery-general anesthesia of the goat].

Shanghai kou qiang yi xue = Shanghai journal of stomatology

Wu ZY.
PMID: 15014851
Shanghai Kou Qiang Yi Xue. 2000 Mar;9(1):42-4.

To find an appropriate anesthesia for the goat in experimental surgery.METHODS:15 goats were operated on with intravenous anestheia using ketamine hydrochloride-gamma-OH-pentobarbital as anesthetic agents.They were grouped according to the weight.The physiologic index,drug dosage,operating time and awaking time were compared.RESULTS:There's...

Changes of intracranial pressure during head-down tilt in anesthetized and conscious rabbits.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology

Tatebayashi K, Doi M, Kawai Y.
PMID: 15002502
J Gravit Physiol. 2002 Jul;9(1):P101-2.

Effects of head-down tilt on intracranial pressure were studied in anesthetized and conscious rabbits. Adult Japanese white rabbits of both sexes, weighing 2.5-3.5 kg, were used in the experiments. Experiment 1. Animals were anesthetized with pentobarbital, and ICP was...

Surgical anaesthesia with pentobarbital prevents the effect of local SCH 23390 on rat striatal acetylcholine release in a strain-dependent manner.

Behavioural pharmacology

Consolo S, Colli E, Caltavuturo C, Di Chiara G.
PMID: 11224463
Behav Pharmacol. 1996 Nov;7(7):663-668.

This study was performed in order to clarify existing discrepancies about the ability of the D1 antagonist SCH 23390 to reduce striatal acetyicholine (ACh) release after intrastriatal application by reverse dialysis. The possibility that negative findings were related to...

Assessment of respiratory muscle effort studying diaphragm movement registered with surface sensors. Animal model (dogs).

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Torres A, Fiz JA, Galdiz B, Gea J, Morera J, Jané R.
PMID: 17271153
Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3917-20. doi: 10.1109/IEMBS.2004.1404095.

The diaphragm movement (DM) signal during spontaneous ventilations is analyzed in this work. The DM signal is acquired by means two surface sensors (a piezoelectric contact sensor -PCS- and a piezoelectric accelerometer -ACP) applied on the costal wall. The...

The relaxing effects of barbiturates in vascular smooth muscle of rat aorta.

Journal of anesthesia

Nishiwada M, Nakamura K, Hatano Y, Mori K.
PMID: 15278607
J Anesth. 1991 Oct;5(4):380-7. doi: 10.1007/s0054010050380.

The effects of thiamylal and pentobarbital on contractions mediated through the influx of extracellular Ca(++) and the release of intracellularly stored Ca(++) were compared in rat aortic strips. Thiamylal (3 x 10(-5) M to 10(-3) M) and pentobarbital (10(-4)...

Paraventricular nucleus connections to spinal cord and pituitary.

Neuroscience letters

Ono T, Nishino H, Sasaka K, Muramoto K, Yano I, Simpson A.
PMID: 19605270
Neurosci Lett. 1978 Nov;10(1):141-6. doi: 10.1016/0304-3940(78)90025-3.

In rats anesthetized with pentobarbital or a mixture of urethane and chloralose, horseradish peroxidase (HRP) was injected into the intermediolateral column of the spinal cord (Th7 and Th9) or the posterior pituitary lobe. HRP positive cells were found mainly...

Electrical stimulation of specific brainstem nuclei suppresses growth hormone-releasing hormone-induced growth hormone secretion in the pentobarbital anaesthetized rat.

Journal of neuroendocrinology

Koibuchi N, Kato M, Kakegawa T, Suzuki M.
PMID: 19210457
J Neuroendocrinol. 1989 Jun 01;1(3):209-14. doi: 10.1111/j.1365-2826.1989.tb00105.x.

Abstract To clarify the neural mechanism related to suppression of growth hormone (GH) secretion, biphasic electrical stimulation was delivered into several brainstem nuclei in the pentobarbital anaesthetized rat. A concentric bipolar stimulating electrode was implanted chronically one week prior...

Localization and functional expression of alternatively spliced forms of the GABA(A) receptor gamma(2) subunit.

Molecular and cellular neurosciences

Sikela JM, Leidenheimer NJ, Gambarana C, Buck KJ, Lin LH, Khan AS, Wilson-Shaw D, Siegel RE.
PMID: 19912817
Mol Cell Neurosci. 1991 Aug;2(4):338-43. doi: 10.1016/1044-7431(91)90064-u.

Recent studies have identified two alternatively spliced forms of the GABA(A) receptor gamma(2) subunit that differ by the presence (gamma(2L)) or absence (gamma(2S)) of an eight-amino acid segment. This insert in the gamma(2L) isoform exists in the proposed cytoplasmic...

Effects of pentobarbital on proopiomelanocortin opioid products of neonatal piglets during normoxia and hypoxia.

Journal of neuroendocrinology

Moss IR, Inman JD.
PMID: 19215492
J Neuroendocrinol. 1991 Aug 01;3(4):455-60. doi: 10.1111/j.1365-2826.1991.tb00303.x.

Abstract Endogenous opioids have been shown to suppress physiological functions in the neonate. It has been suggested that anesthesia with barbiturates might enhance this suppression by influencing opioid systems directly. To explore this possibility, naive piglets, 2.2+/-0.8 (X+/-SD) days...

Yokukansan Enhances Pentobarbital-Induced Sleep in Socially Isolated Mice: Possible Involvement of GABA(A) - Benzodiazepine Receptor Complex.

Journal of pharmacological sciences

Egashira N, Nogami A, Iwasaki K, Ishibashi A, Uchida N, Takasaki K, Mishima K, Nishimura R, Oishi R, Fujiwara M.
PMID: 21691038
J Pharmacol Sci. 2011;116(3):316-20. Epub 2011 Jun 18.

In the present study, we investigated the effect of the Kampo medicine Yokukansan (YKS) on pentobarbital-induced sleep in group-housed and socially isolated mice. Socially isolated mice showed shorter sleeping time than the group-housed mice. YKS (300 mg/kg, p.o.) prolonged...

Showing 13 to 24 of 395 entries