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Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis.

Natural product reports

Zhou K, Yang S, Li SM.
PMID: 33972962
Nat Prod Rep. 2021 Dec 15;38(12):2236-2260. doi: 10.1039/d0np00083c.

Covering: up to July 2020Naturally occurring chalcones carrying up to three modified or unmodified C

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Zhou K, Yang S, Li SM. Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis. Nat Prod Rep. 2021;38(12):2236-2260doi: 10.1039/d0np00083c.
Zhou, K., Yang, S., & Li, S. M. (2021). Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis. Natural product reports, 38(12), 2236-2260. https://doi.org/10.1039/d0np00083c
Zhou, Kang, et al. "Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis." Natural product reports vol. 38,12 (2021): 2236-2260. doi: https://doi.org/10.1039/d0np00083c
Zhou K, Yang S, Li SM. Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis. Nat Prod Rep. 2021 Dec 15;38(12):2236-2260. doi: 10.1039/d0np00083c. PMID: 33972962.
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Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors.

Archiv der Pharmazie

Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI.
PMID: 34313342
Arch Pharm (Weinheim). 2021 Nov;354(11):e2100202. doi: 10.1002/ardp.202100202. Epub 2021 Jul 27.

Novel series of imidazo[2,1-b]thiazole analogs were designed, synthesized, and biologically evaluated as indoleamine 2,3-dioxygenase (IDO1) inhibitors. Imidazo[2,1-b]thiazoles 6, 7, and 8 showed inhibitory profiles against IDO1 at IC

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Ewida MA, Ewida HA, Ahmed MS, et al. Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors. Arch Pharm (Weinheim). 2021;354(11):e2100202doi: 10.1002/ardp.202100202.
Ewida, M. A., Ewida, H. A., Ahmed, M. S., Allam, H. A., ElBagary, R. I., George, R. F., Georgey, H. H., & El-Subbagh, H. I. (2021). Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors. Archiv der Pharmazie, 354(11), e2100202. https://doi.org/10.1002/ardp.202100202
Ewida, Menna A, et al. "Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors." Archiv der Pharmazie vol. 354,11 (2021): e2100202. doi: https://doi.org/10.1002/ardp.202100202
Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI. Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors. Arch Pharm (Weinheim). 2021 Nov;354(11):e2100202. doi: 10.1002/ardp.202100202. Epub 2021 Jul 27. PMID: 34313342.
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[When was pharmacology finally established in all pharmaceutical institutes and faculties in Germany?].

Pharmazie in unserer Zeit

Ammon HP.
PMID: 9718966
Pharm Unserer Zeit. 1998 Jul;27(4):141. doi: 10.1002/pauz.19980270402.

No abstract available.

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Ammon HP. Wann wird die Pharmakologie endlich an allen Pharmazeutischen Instituten/Fakultäten in Deutschland etabliert? [When was pharmacology finally established in all pharmaceutical institutes and faculties in Germany?]. Pharm Unserer Zeit. 1998;27(4):141doi: 10.1002/pauz.19980270402.
Ammon, H. P. (1998). Wann wird die Pharmakologie endlich an allen Pharmazeutischen Instituten/Fakultäten in Deutschland etabliert? [When was pharmacology finally established in all pharmaceutical institutes and faculties in Germany?]. Pharmazie in unserer Zeit, 27(4), 141. https://doi.org/10.1002/pauz.19980270402
Ammon, H P. "Wann wird die Pharmakologie endlich an allen Pharmazeutischen Instituten/Fakultäten in Deutschland etabliert?" [When was pharmacology finally established in all pharmaceutical institutes and faculties in Germany?]. Pharmazie in unserer Zeit vol. 27,4 (1998): 141. doi: https://doi.org/10.1002/pauz.19980270402
Ammon HP. Wann wird die Pharmakologie endlich an allen Pharmazeutischen Instituten/Fakultäten in Deutschland etabliert? [When was pharmacology finally established in all pharmaceutical institutes and faculties in Germany?]. Pharm Unserer Zeit. 1998 Jul;27(4):141. doi: 10.1002/pauz.19980270402. German. PMID: 9718966.
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A "Pretender" Croconate-Bridged Macrocyclic Tetraruthenium Complex: Sizable Redox Potential Splittings despite Electronically Insulated Divinylphenylene Diruthenium Entities.

Molecules (Basel, Switzerland)

Rotthowe N, Linseis M, Vogelsang L, Orth N, Ivanović-Burmazović I, Winter RF.
PMID: 34500666
Molecules. 2021 Aug 29;26(17). doi: 10.3390/molecules26175232.

Careful optimization of the reaction conditions provided access to the particularly small tetraruthenium macrocycle

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Rotthowe N, Linseis M, Vogelsang L, et al. A "Pretender" Croconate-Bridged Macrocyclic Tetraruthenium Complex: Sizable Redox Potential Splittings despite Electronically Insulated Divinylphenylene Diruthenium Entities. Molecules. 2021;26(17)doi: 10.3390/molecules26175232.
Rotthowe, N., Linseis, M., Vogelsang, L., Orth, N., Ivanović-Burmazović, I., & Winter, R. F. (2021). A "Pretender" Croconate-Bridged Macrocyclic Tetraruthenium Complex: Sizable Redox Potential Splittings despite Electronically Insulated Divinylphenylene Diruthenium Entities. Molecules (Basel, Switzerland), 26(17), . https://doi.org/10.3390/molecules26175232
Rotthowe, Nils, et al. "A "Pretender" Croconate-Bridged Macrocyclic Tetraruthenium Complex: Sizable Redox Potential Splittings despite Electronically Insulated Divinylphenylene Diruthenium Entities." Molecules (Basel, Switzerland) vol. 26,17 (2021). doi: https://doi.org/10.3390/molecules26175232
Rotthowe N, Linseis M, Vogelsang L, Orth N, Ivanović-Burmazović I, Winter RF. A "Pretender" Croconate-Bridged Macrocyclic Tetraruthenium Complex: Sizable Redox Potential Splittings despite Electronically Insulated Divinylphenylene Diruthenium Entities. Molecules. 2021 Aug 29;26(17). doi: 10.3390/molecules26175232. PMID: 34500666; PMCID: PMC8433806.
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Perfluorinated Trialkoxysilanol with Dramatically Increased Brønsted Acidity.

Chemistry (Weinheim an der Bergstrasse, Germany)

Feige F, Malaspina LA, Rychagova E, Ketkov S, Grabowsky S, Hupf E, Beckmann J.
PMID: 34550614
Chemistry. 2021 Nov 17;27(64):15898-15902. doi: 10.1002/chem.202103177. Epub 2021 Oct 14.

The Brønsted acidity of the perfluorinated trialkoxysilanol {(F

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Feige F, Malaspina LA, Rychagova E, et al. Perfluorinated Trialkoxysilanol with Dramatically Increased Brønsted Acidity. Chemistry. 2021;27(64):15898-15902doi: 10.1002/chem.202103177.
Feige, F., Malaspina, L. A., Rychagova, E., Ketkov, S., Grabowsky, S., Hupf, E., & Beckmann, J. (2021). Perfluorinated Trialkoxysilanol with Dramatically Increased Brønsted Acidity. Chemistry (Weinheim an der Bergstrasse, Germany), 27(64), 15898-15902. https://doi.org/10.1002/chem.202103177
Feige, Felix, et al. "Perfluorinated Trialkoxysilanol with Dramatically Increased Brønsted Acidity." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 27,64 (2021): 15898-15902. doi: https://doi.org/10.1002/chem.202103177
Feige F, Malaspina LA, Rychagova E, Ketkov S, Grabowsky S, Hupf E, Beckmann J. Perfluorinated Trialkoxysilanol with Dramatically Increased Brønsted Acidity. Chemistry. 2021 Nov 17;27(64):15898-15902. doi: 10.1002/chem.202103177. Epub 2021 Oct 14. PMID: 34550614.
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Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors.

Archiv der Pharmazie

Gümüş M, Babacan ŞN, Demir Y, Sert Y, Koca İ, Gülçin İ.
PMID: 34609760
Arch Pharm (Weinheim). 2021 Oct 05;e2100242. doi: 10.1002/ardp.202100242. Epub 2021 Oct 05.

Human carbonic anhydrase (hCA) isoenzymes are zinc ion-containing, widespread metalloenzymes and they classically play a role in pH homeostasis maintenance. CA inhibitors suppress the CA activity and their usage has been clinically established as antiglaucoma agents, antiepileptics, diuretics, and...

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Gümüş M, Babacan ŞN, Demir Y, et al. Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors. Arch Pharm (Weinheim). 2021;e2100242doi: 10.1002/ardp.202100242.
Gümüş, M., Babacan, �. �. N., Demir, Y., Sert, Y., Koca, �. �., & Gülçin, �. �. (2021). Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors. Archiv der Pharmazie, e2100242. https://doi.org/10.1002/ardp.202100242
Gümüş, Mehmet, et al. "Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors." Archiv der Pharmazie vol. (2021): e2100242. doi: https://doi.org/10.1002/ardp.202100242
Gümüş M, Babacan ŞN, Demir Y, Sert Y, Koca İ, Gülçin İ. Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors. Arch Pharm (Weinheim). 2021 Oct 05;e2100242. doi: 10.1002/ardp.202100242. Epub 2021 Oct 05. PMID: 34609760.
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Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies.

Archiv der Pharmazie

Shahrivar-Gargari M, Hamzeh-Mivehroud M, Hemmati S, Mojarrad JS, Tüylü Küçükkılınç T, Ayazgök B, Dastmalchi S.
PMID: 33872422
Arch Pharm (Weinheim). 2021 Jul;354(7):e2000453. doi: 10.1002/ardp.202000453. Epub 2021 Apr 19.

Inspired by the structures of donepezil and rivastigmine, a novel series of indanone-carbamate hybrids was synthesized using the pharmacophore hybridization-based design strategy, and their biological activities toward acetylcholinesterase (AChE) and butyrylcholinesterase were evaluated. Among the synthesized compounds, 4d and...

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Shahrivar-Gargari M, Hamzeh-Mivehroud M, Hemmati S, et al. Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies. Arch Pharm (Weinheim). 2021;354(7):e2000453doi: 10.1002/ardp.202000453.
Shahrivar-Gargari, M., Hamzeh-Mivehroud, M., Hemmati, S., Mojarrad, J. S., Tüylü Küçükkılınç, T., Ayazgök, B., & Dastmalchi, S. (2021). Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies. Archiv der Pharmazie, 354(7), e2000453. https://doi.org/10.1002/ardp.202000453
Shahrivar-Gargari, Mohammad, et al. "Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies." Archiv der Pharmazie vol. 354,7 (2021): e2000453. doi: https://doi.org/10.1002/ardp.202000453
Shahrivar-Gargari M, Hamzeh-Mivehroud M, Hemmati S, Mojarrad JS, Tüylü Küçükkılınç T, Ayazgök B, Dastmalchi S. Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies. Arch Pharm (Weinheim). 2021 Jul;354(7):e2000453. doi: 10.1002/ardp.202000453. Epub 2021 Apr 19. PMID: 33872422.
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Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents.

Archiv der Pharmazie

Ragab FA, Eissa AAM, Fahim SH, Salem MA, Gamal MA, Nissan YM.
PMID: 33872414
Arch Pharm (Weinheim). 2021 Aug;354(8):e2100029. doi: 10.1002/ardp.202100029. Epub 2021 Apr 19.

New coumarin derivatives 9a-f, 10a-e, and 11a-f were synthesized and evaluated for their cytotoxic activity against a human breast cancer cell line (MCF-7). All compounds exhibited good activity in the nanomolar range, using doxorubicin and erlotinib as positive controls....

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Ragab FA, Eissa AAM, Fahim SH, et al. Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents. Arch Pharm (Weinheim). 2021;354(8):e2100029doi: 10.1002/ardp.202100029.
Ragab, F. A., Eissa, A. A. M., Fahim, S. H., Salem, M. A., Gamal, M. A., & Nissan, Y. M. (2021). Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents. Archiv der Pharmazie, 354(8), e2100029. https://doi.org/10.1002/ardp.202100029
Ragab, Fatma A, et al. "Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents." Archiv der Pharmazie vol. 354,8 (2021): e2100029. doi: https://doi.org/10.1002/ardp.202100029
Ragab FA, Eissa AAM, Fahim SH, Salem MA, Gamal MA, Nissan YM. Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents. Arch Pharm (Weinheim). 2021 Aug;354(8):e2100029. doi: 10.1002/ardp.202100029. Epub 2021 Apr 19. PMID: 33872414.
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Showing 913 to 920 of 920 entries