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Showing 25 to 36 of 136 entries
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Pharmacological and Biophysical Characteristics of Picrotoxin-Resistant, δSubunit-Containing GABA.

Frontiers in synaptic neuroscience

Shu HJ, Lu X, Bracamontes J, Steinbach JH, Zorumski CF, Mennerick S.
PMID: 34867260
Front Synaptic Neurosci. 2021 Nov 18;13:763411. doi: 10.3389/fnsyn.2021.763411. eCollection 2021.

GABA

Segregation of Acetylcholine and GABA in the Rat Superior Cervical Ganglia: Functional Correlation.

Frontiers in cellular neuroscience

Elinos D, Rodríguez R, Martínez LA, Zetina ME, Cifuentes F, Morales MA.
PMID: 27092054
Front Cell Neurosci. 2016 Apr 07;10:91. doi: 10.3389/fncel.2016.00091. eCollection 2016.

Sympathetic neurons have the capability to segregate their neurotransmitters (NTs) and co-transmitters to separate varicosities of single axons; furthermore, in culture, these neurons can even segregate classical transmitters. In vivo sympathetic neurons employ acetylcholine (ACh) and other classical NTs...

Onset Characteristics of Long-Term Potentiation in the Guinea-Pig Hippocampal CA1 Region in Vitro.

The European journal of neuroscience

Gustafsson B, Asztely F, Hanse E, Wigström H.
PMID: 12106147
Eur J Neurosci. 1989 Jul;1(4):382-394. doi: 10.1111/j.1460-9568.1989.tb00803.x.

The temporal development of long-term potentiation (LTP) was examined in the CA1 region of the hippocampal slice preparation (bath temperature 30 degrees C). LTP was evoked by a single brief afferent tetanus (3 - 40 impulses at 50 Hz)...

Pharmacological and Electrophysiological Properties of Recombinant GABAA Receptors Comprising the alpha3, beta1 and gamma2 Subunits.

The European journal of neuroscience

Knoflach F, Backus KH, Giller T, Malherbe P, Pflimlin P, Möhler H, Trube G.
PMID: 12106436
Eur J Neurosci. 1992 Oct;4(1):1-9. doi: 10.1111/j.1460-9568.1992.tb00103.x.

To assess the role of subunits for channel function and drug modulation in recombinant GABAA receptors, the alpha3beta1gamma2 subunits and the dual combinations alpha3beta1, beta1gamma2 and alpha3gamma2 were expressed by transfection of human embryonic kidney cells and by RNA...

Effects of nicotinic and muscarinic ligands on embryonic neurones of Periplaneta americana in primary culture: a whole cell clamp study.

Journal of insect physiology

Pichon Y, Guillet JC, Le Guen J, Tiaho F, Van Eyseren I.
PMID: 12769957
J Insect Physiol. 1998 Mar;44(3):227-240. doi: 10.1016/s0022-1910(97)00165-0.

The pharmacological properties of acetylcholine (ACh) receptors of cultured neurones from embryonic cockroach brains were studied using the whole-cell configuration of the patch-clamp technique. More than 90% of the studied neurones responded to ACh by a monophasic inward current,...

Neuroendocrine control of diapause hormone secretion in the silkworm, Bombyx mori.

Journal of insect physiology

Ichikawa T, Aoki S, Shimizu I.
PMID: 12770482
J Insect Physiol. 1997 Nov;43(12):1101-1109. doi: 10.1016/s0022-1910(97)00083-8.

To clarify the control mechanism of diapause hormone (DH) secretion in the silkworm Bombyx mori a series of anatomical and pharmacological experiments were carried out. The arrangement of 'diapause' and 'non-diapause' eggs in the ovarioles of the moths was...

Anxiolytic Action of Taurine via Intranasal Administration in Mice.

Biomolecules & therapeutics

Jung JH, Kim SJ.
PMID: 30917626
Biomol Ther (Seoul). 2019 Mar 25;27(5):450-456. doi: 10.4062/biomolther.2018.218. Epub 2019 Mar 25.

Taurine has a number of beneficial pharmacological actions in the brain such as anxiolytic and neuroprotective actions. We explored to test whether taurine could be transported to the central nervous system through the intranasal route. Following intranasal administration of...

Acute effects of ethanol on GABA.

Open journal of neuroscience

Xie Z, Li G, Ye JH.
PMID: 28066680
Open J Neurosci. 2013;3. doi: 10.13055/ojns_3_1_5.130821. Epub 2013 Aug 21.

Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the lateral habenula (LHb) has attracted a great deal of attention as another target for abused drugs in the brain because its role in regulating...

Effects of dopamine D.

Eye and vision (London, England)

Popova E, Kostov M, Kupenova P.
PMID: 27981058
Eye Vis (Lond). 2016 Dec 07;3:32. doi: 10.1186/s40662-016-0064-4. eCollection 2016.

BACKGROUND: Some data indicate that the dopaminergic and GABAergic systems interact in the vertebrate retina, but the type of interactions is not well understood.METHODS: In this study we investigated the effect of dopamine DRESULTS: We found that SCH 23390...

Anticonvulsant effect of liraglutide, GLP-1 agonist by averting a change in GABA and brain glutathione level on picrotoxin-induced seizures.

EXCLI journal

Gupta G, Dahiya R, Dua K, Chellappan DK, Tiwari J, Narayan Sharma G, Kumar Singh S, Mishra A, Kumar Sharma R, Agrawal M.
PMID: 28827991
EXCLI J. 2017 May 19;16:752-754. doi: 10.17179/excli2017-283. eCollection 2017.

No abstract available.

Effect of Gentiana olivieri on experimental epilepsy models.

Pharmacognosy magazine

Aslan M, Orhan DD, Orhan N.
PMID: 22262939
Pharmacogn Mag. 2011 Oct;7(28):344-9. doi: 10.4103/0973-1296.90419.

BACKGROUND: Flowering herbs of Gentiana olivieri Griseb. (Gentianaceae) are widely used as bitter tonic, stomachic, stimulant of appetite, antipyretic, anticonvulsant, antidiabetic and for mental problems in the different regions of Turkey.OBJECTIVE: To establish the anticonvulsant activity potential of G....

Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Yin H, Yang EJ, Park SJ, Han SK.
PMID: 22128261
Korean J Physiol Pharmacol. 2011 Oct;15(5):285-9. doi: 10.4196/kjpp.2011.15.5.285. Epub 2011 Oct 31.

Shilajit, a medicine herb commonly used in Ayurveda, has been reported to contain at least 85 minerals in ionic form that act on a variety of chemical, biological, and physical stressors. The substantia gelatinosa (SG) neurons of the trigeminal...

Showing 25 to 36 of 136 entries