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Showing 205 to 213 of 213 entries
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The One-Stop Gyrification Station - Challenges and New Technologies.

Progress in neurobiology

Hickmott RA, Bosakhar A, Quezada S, Barresi M, Walker DW, Ryan AL, Quigley A, Tolcos M.
PMID: 34166774
Prog Neurobiol. 2021 Sep;204:102111. doi: 10.1016/j.pneurobio.2021.102111. Epub 2021 Jun 21.

The evolution of the folded cortical surface is an iconic feature of the human brain shared by a subset of mammals and considered pivotal for the emergence of higher-order cognitive functions. While our understanding of the neurodevelopmental processes involved...

Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function.

Progress in neurobiology

Schneider F, Duong TA, Metz I, Winkelmeier J, Hübner CA, Endesfelder U, Rust MB.
PMID: 33845164
Prog Neurobiol. 2021 Jul;202:102050. doi: 10.1016/j.pneurobio.2021.102050. Epub 2021 Apr 18.

Neuron connectivity depends on growth cones that navigate axons through the developing brain. Growth cones protrude and retract actin-rich structures to sense guidance cues. These cues control local actin dynamics and steer growth cones towards attractants and away from...

Emergence of abstract sound representations in the ascending auditory system.

Progress in neurobiology

Harpaz M, Jankowski MM, Khouri L, Nelken I.
PMID: 33845166
Prog Neurobiol. 2021 Jul;202:102049. doi: 10.1016/j.pneurobio.2021.102049. Epub 2021 Apr 15.

Auditory processing begins by decomposing sounds into their frequency components, raising the question of where the representation of sounds as wholes emerges in the auditory system. To address this question, we used stimulus-specific adaptation (SSA), the reduction in the...

c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning.

Progress in neurobiology

González-Martín A, Moyano T, Gutiérrez DA, Carvajal FJ, Cerpa W, Hanley JG, Gutiérrez RA, Álvarez AR.
PMID: 34284000
Prog Neurobiol. 2021 Oct;205:102122. doi: 10.1016/j.pneurobio.2021.102122. Epub 2021 Jul 18.

Memory consolidation requires activation of a gene expression program that allows de novo protein synthesis. But the molecular mechanisms that favour or restrict that program are poorly understood. The kinase c-Abl can modulate gene expression through transcription factors and...

From Alpha Diversity to Zzz: Interactions among sleep, the brain, and gut microbiota in the first year of life.

Progress in neurobiology

Schoch SF, Castro-Mejía JL, Krych L, Leng B, Kot W, Kohler M, Huber R, Rogler G, Biedermann L, Walser JC, Nielsen DS, Kurth S.
PMID: 34923049
Prog Neurobiol. 2021 Dec 16;102208. doi: 10.1016/j.pneurobio.2021.102208. Epub 2021 Dec 16.

Sleep disorders have been linked to alterations of gut microbiota composition in adult humans and animal models, but it is unclear how this link develops. With longitudinal assessments in 162 healthy infants, we present a so far unrecognized sleep-brain-gut...

The role of Extracellular Vesicles during CNS development.

Progress in neurobiology

Bahram Sangani N, Gomes AR, Curfs LMG, Reutelingsperger CP.
PMID: 34314775
Prog Neurobiol. 2021 Oct;205:102124. doi: 10.1016/j.pneurobio.2021.102124. Epub 2021 Jul 24.

With a diverse set of neuronal and glial cell populations, Central Nervous System (CNS) has one of the most complex structures in the body. Intercellular communication is therefore highly important to coordinate cell-to-cell interactions. Besides electrical and chemical messengers,...

Reactive astrocytes prevent maladaptive plasticity after ischemic stroke.

Progress in neurobiology

Aswendt M, Wilhelmsson U, Wieters F, Stokowska A, Schmitt FJ, Pallast N, de Pablo Y, Mohammed L, Hoehn M, Pekna M, Pekny M.
PMID: 34921928
Prog Neurobiol. 2021 Dec 15;209:102199. doi: 10.1016/j.pneurobio.2021.102199. Epub 2021 Dec 15.

Restoration of functional connectivity is a major contributor to functional recovery after stroke. We investigated the role of reactive astrocytes in functional connectivity and recovery after photothrombotic stroke in mice with attenuated reactive gliosis (GFAP

Causal role of cross-frequency coupling in distinct components of cognitive control.

Progress in neurobiology

Riddle J, McFerren A, Frohlich F.
PMID: 33741402
Prog Neurobiol. 2021 Jul;202:102033. doi: 10.1016/j.pneurobio.2021.102033. Epub 2021 Mar 16.

Cognitive control is the capacity to guide motor and perceptual systems towards abstract goals. High-frequency neural oscillations related to motor activity in the beta band (13-30 Hz) and to visual processing in the gamma band (>30 Hz) are known...

Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease.

Progress in neurobiology

La Barbera L, Vedele F, Nobili A, Krashia P, Spoleti E, Latagliata EC, Cutuli D, Cauzzi E, Marino R, Viscomi MT, Petrosini L, Puglisi-Allegra S, Melone M, Keller F, Mercuri NB, Conti F, D'Amelio M.
PMID: 33684513
Prog Neurobiol. 2021 Jul;202:102031. doi: 10.1016/j.pneurobio.2021.102031. Epub 2021 Mar 05.

What happens precociously to the brain destined to develop Alzheimer's Disease (AD) still remains to be elucidated and this is one reason why effective AD treatments are missing. Recent experimental and clinical studies indicate that the degeneration of the...

Showing 205 to 213 of 213 entries