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Showing 13 to 24 of 90 entries
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Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD .

Life (Basel, Switzerland)

Yarlagadda S, Kulis C, Noakes PG, Smythe ML.
PMID: 34575143
Life (Basel). 2021 Sep 21;11(9). doi: 10.3390/life11090994.

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness and wasting due to the lack of dystrophin protein. The acute phase of DMD is characterized by muscle necrosis and increased levels of the pro-inflammatory mediator, prostaglandin D2 (PGD2)....

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Yarlagadda S, Kulis C, Noakes PG, et al. Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD . Life (Basel). 2021;11(9)doi: 10.3390/life11090994.
Yarlagadda, S., Kulis, C., Noakes, P. G., & Smythe, M. L. (2021). Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD . Life (Basel, Switzerland), 11(9), . https://doi.org/10.3390/life11090994
Yarlagadda, Sai, et al. "Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD ." Life (Basel, Switzerland) vol. 11,9 (2021). doi: https://doi.org/10.3390/life11090994
Yarlagadda S, Kulis C, Noakes PG, Smythe ML. Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD . Life (Basel). 2021 Sep 21;11(9). doi: 10.3390/life11090994. PMID: 34575143; PMCID: PMC8469723.
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Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma.

Experimental and therapeutic medicine

Zhang W, Shang S, Yang Y, Lu P, Wang T, Cui X, Tang X.
PMID: 32256782
Exp Ther Med. 2020 Apr;19(4):2963-2972. doi: 10.3892/etm.2020.8554. Epub 2020 Feb 26.

Pancreatic adenocarcinoma (PAAD) is a painful and fatal disease that undoubtedly remains a health care priority and offers significant therapeutic challenges. The significance of epigenetic modifications, including DNA methylation in tumor development, has gained the attention of researchers. Identifying...

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Zhang W, Shang S, Yang Y, et al. Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma. Exp Ther Med. 2020;19(4):2963-2972doi: 10.3892/etm.2020.8554.
Zhang, W., Shang, S., Yang, Y., Lu, P., Wang, T., Cui, X., & Tang, X. (2020). Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma. Experimental and therapeutic medicine, 19(4), 2963-2972. https://doi.org/10.3892/etm.2020.8554
Zhang, Wei, et al. "Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma." Experimental and therapeutic medicine vol. 19,4 (2020): 2963-2972. doi: https://doi.org/10.3892/etm.2020.8554
Zhang W, Shang S, Yang Y, Lu P, Wang T, Cui X, Tang X. Identification of DNA methylation-driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinoma. Exp Ther Med. 2020 Apr;19(4):2963-2972. doi: 10.3892/etm.2020.8554. Epub 2020 Feb 26. PMID: 32256782; PMCID: PMC7086284.
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The Leptomeninges Produce Prostaglandin D.

Frontiers in cellular neuroscience

Cherasse Y, Aritake K, Oishi Y, Kaushik MK, Korkutata M, Urade Y.
PMID: 30364224
Front Cell Neurosci. 2018 Oct 11;12:357. doi: 10.3389/fncel.2018.00357. eCollection 2018.

Injection of nanomolar amounts of prostaglandin D

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Cherasse Y, Aritake K, Oishi Y, et al. The Leptomeninges Produce Prostaglandin D. Front Cell Neurosci. 2018;12:357doi: 10.3389/fncel.2018.00357.
Cherasse, Y., Aritake, K., Oishi, Y., Kaushik, M. K., Korkutata, M., & Urade, Y. (2018). The Leptomeninges Produce Prostaglandin D. Frontiers in cellular neuroscience, 12357. https://doi.org/10.3389/fncel.2018.00357
Cherasse, Yoan, et al. "The Leptomeninges Produce Prostaglandin D." Frontiers in cellular neuroscience vol. 12 (2018): 357. doi: https://doi.org/10.3389/fncel.2018.00357
Cherasse Y, Aritake K, Oishi Y, Kaushik MK, Korkutata M, Urade Y. The Leptomeninges Produce Prostaglandin D. Front Cell Neurosci. 2018 Oct 11;12:357. doi: 10.3389/fncel.2018.00357. eCollection 2018. PMID: 30364224; PMCID: PMC6193105.
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Vitamin D deficiency and fatigue: an unusual presentation.

SpringerPlus

Johnson K, Sattari M.
PMID: 26543719
Springerplus. 2015 Oct 07;4:584. doi: 10.1186/s40064-015-1376-x. eCollection 2015.

Fatigue is a vague but common complaint that is poorly characterized by physicians as well as patients. While fatigue may result from a number of different etiologies, at the present time, a comprehensive approach to each patient with fatigue...

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Johnson K, Sattari M. Vitamin D deficiency and fatigue: an unusual presentation. Springerplus. 2015;4:584doi: 10.1186/s40064-015-1376-x.
Johnson, K., & Sattari, M. (2015). Vitamin D deficiency and fatigue: an unusual presentation. SpringerPlus, 4584. https://doi.org/10.1186/s40064-015-1376-x
Johnson, Kevin, and Sattari, Maryam. "Vitamin D deficiency and fatigue: an unusual presentation." SpringerPlus vol. 4 (2015): 584. doi: https://doi.org/10.1186/s40064-015-1376-x
Johnson K, Sattari M. Vitamin D deficiency and fatigue: an unusual presentation. Springerplus. 2015 Oct 07;4:584. doi: 10.1186/s40064-015-1376-x. eCollection 2015. PMID: 26543719; PMCID: PMC4628075.
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Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Zhang Y, Li X, Liu LP, Hong L, Liu X, Zhang B, Wu CZ, Cui X.
PMID: 28461771
Korean J Physiol Pharmacol. 2017 May;21(3):293-300. doi: 10.4196/kjpp.2017.21.3.293. Epub 2017 Apr 21.

Prostaglandin D

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Zhang Y, Li X, Liu LP, et al. Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D. Korean J Physiol Pharmacol. 2017;21(3):293-300doi: 10.4196/kjpp.2017.21.3.293.
Zhang, Y., Li, X., Liu, L. P., Hong, L., Liu, X., Zhang, B., Wu, C. Z., & Cui, X. (2017). Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(3), 293-300. https://doi.org/10.4196/kjpp.2017.21.3.293
Zhang, Ying, et al. "Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 21,3 (2017): 293-300. doi: https://doi.org/10.4196/kjpp.2017.21.3.293
Zhang Y, Li X, Liu LP, Hong L, Liu X, Zhang B, Wu CZ, Cui X. Peroxisome proliferator-activated receptor γ is essential for secretion of ANP induced by prostaglandin D. Korean J Physiol Pharmacol. 2017 May;21(3):293-300. doi: 10.4196/kjpp.2017.21.3.293. Epub 2017 Apr 21. PMID: 28461771; PMCID: PMC5409115.
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[No title available]

Arerugi = [Allergy]

[No authors listed]
PMID: 30787244
Arerugi. 2019;68(1):54-55. doi: 10.15036/arerugi.68.54.

No abstract available.

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. Arerugi. 2019;68(1):54-55doi: 10.15036/arerugi.68.54.
(2019). . Arerugi = [Allergy], 68(1), 54-55. https://doi.org/10.15036/arerugi.68.54
"." Arerugi = [Allergy] vol. 68,1 (2019): 54-55. doi: https://doi.org/10.15036/arerugi.68.54
. Arerugi. 2019;68(1):54-55. doi: 10.15036/arerugi.68.54. Japanese. PMID: 30787244.
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Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia.

Journal of nephropathology

Maesaka JK, Sodam B, Palaia T, Ragolia L, Batuman V, Miyawaki N, Shastry S, Youmans S, El-Sabban M.
PMID: 24475446
J Nephropathol. 2013 Jul;2(3):166-80. doi: 10.12860/JNP.2013.28. Epub 2013 Jul 01.

BACKGROUND: Apoptosis, reactive oxygen species (ROS) and inflammatory cytokines have all been implicated in the development of Alzheimer's disease (AD).OBJECTIVES: The present study identifies the apoptotic factor that was responsible for the fourfold increase in apoptotic rates that we...

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Maesaka JK, Sodam B, Palaia T, et al. Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia. J Nephropathol. 2013;2(3):166-80doi: 10.12860/JNP.2013.28.
Maesaka, J. K., Sodam, B., Palaia, T., Ragolia, L., Batuman, V., Miyawaki, N., Shastry, S., Youmans, S., & El-Sabban, M. (2013). Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia. Journal of nephropathology, 2(3), 166-80. https://doi.org/10.12860/JNP.2013.28
Maesaka, John K, et al. "Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia." Journal of nephropathology vol. 2,3 (2013): 166-80. doi: https://doi.org/10.12860/JNP.2013.28
Maesaka JK, Sodam B, Palaia T, Ragolia L, Batuman V, Miyawaki N, Shastry S, Youmans S, El-Sabban M. Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia. J Nephropathol. 2013 Jul;2(3):166-80. doi: 10.12860/JNP.2013.28. Epub 2013 Jul 01. PMID: 24475446; PMCID: PMC3891133.
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Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels.

Biomolecules & therapeutics

Li X, Lu Y, Jin Y, Son JK, Lee SH, Chang HW.
PMID: 24596618
Biomol Ther (Seoul). 2014 Jan;22(1):27-34. doi: 10.4062/biomolther.2013.092.

Curcumin is naturally occurring polyphenolic compound found in turmeric and has many pharmacological activities. The present study was undertaken to evaluate anti-allergic inflammatory activity of curcumin, and to investigate its inhibitory mechanisms in immunoglobulin E (IgE)/Ag-induced mouse bone marrow-derived...

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Li X, Lu Y, Jin Y, et al. Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels. Biomol Ther (Seoul). 2014;22(1):27-34doi: 10.4062/biomolther.2013.092.
Li, X., Lu, Y., Jin, Y., Son, J. K., Lee, S. H., & Chang, H. W. (2014). Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels. Biomolecules & therapeutics, 22(1), 27-34. https://doi.org/10.4062/biomolther.2013.092
Li, Xian, et al. "Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels." Biomolecules & therapeutics vol. 22,1 (2014): 27-34. doi: https://doi.org/10.4062/biomolther.2013.092
Li X, Lu Y, Jin Y, Son JK, Lee SH, Chang HW. Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels. Biomol Ther (Seoul). 2014 Jan;22(1):27-34. doi: 10.4062/biomolther.2013.092. PMID: 24596618; PMCID: PMC3936421.
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Eosinophils in human oral squamous carcinoma; role of prostaglandin D2.

Journal of inflammation (London, England)

Davoine F, Sim A, Tang C, Fisher S, Ethier C, Puttagunta L, Wu Y, McGaw WT, Yu D, Cameron L, Adamko DJ, Moqbel R.
PMID: 23369060
J Inflamm (Lond). 2013 Jan 31;10(1):4. doi: 10.1186/1476-9255-10-4.

Eosinophils are often predominant inflammatory leukocytes infiltrating oral squamous carcinoma (OSC) sites. Prostaglandins are secreted by oral carcinomas and may be involved in eosinophil infiltration. The objective of this study was to determine the factors contributing to eosinophil migration...

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Davoine F, Sim A, Tang C, et al. Eosinophils in human oral squamous carcinoma; role of prostaglandin D2. J Inflamm (Lond). 2013;10(1):4doi: 10.1186/1476-9255-10-4.
Davoine, F., Sim, A., Tang, C., Fisher, S., Ethier, C., Puttagunta, L., Wu, Y., McGaw, W. T., Yu, D., Cameron, L., Adamko, D. J., & Moqbel, R. (2013). Eosinophils in human oral squamous carcinoma; role of prostaglandin D2. Journal of inflammation (London, England), 10(1), 4. https://doi.org/10.1186/1476-9255-10-4
Davoine, Francis, et al. "Eosinophils in human oral squamous carcinoma; role of prostaglandin D2." Journal of inflammation (London, England) vol. 10,1 (2013): 4. doi: https://doi.org/10.1186/1476-9255-10-4
Davoine F, Sim A, Tang C, Fisher S, Ethier C, Puttagunta L, Wu Y, McGaw WT, Yu D, Cameron L, Adamko DJ, Moqbel R. Eosinophils in human oral squamous carcinoma; role of prostaglandin D2. J Inflamm (Lond). 2013 Jan 31;10(1):4. doi: 10.1186/1476-9255-10-4. PMID: 23369060; PMCID: PMC3637094.
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Elevated haptoglobin level of cerebrospinal fluid in Guillain-Barré syndrome revealed by proteomics analysis.

Proteomics. Clinical applications

Chang KH, Lyu RK, Tseng MY, Ro LS, Wu YR, Chang HS, Hsu WC, Kuo HC, Huang CC, Chu CC, Hsieh SY, Chen CM.
PMID: 21136698
Proteomics Clin Appl. 2007 May;1(5):467-75. doi: 10.1002/prca.200600949. Epub 2007 Apr 19.

Guillain-Barré Syndrome (GBS) is a rare autoimmune inflammatory polyneuropathy with a high risk of respiratory failure and unclear pathogenesis. Currently, there are no valid biomarkers for diagnosis of GBS. We used 2-DE and MS to analyze the protein profiles...

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Chang KH, Lyu RK, Tseng MY, et al. Elevated haptoglobin level of cerebrospinal fluid in Guillain-Barré syndrome revealed by proteomics analysis. Proteomics Clin Appl. 2007;1(5):467-75doi: 10.1002/prca.200600949.
Chang, K. H., Lyu, R. K., Tseng, M. Y., Ro, L. S., Wu, Y. R., Chang, H. S., Hsu, W. C., Kuo, H. C., Huang, C. C., Chu, C. C., Hsieh, S. Y., & Chen, C. M. (2007). Elevated haptoglobin level of cerebrospinal fluid in Guillain-Barré syndrome revealed by proteomics analysis. Proteomics. Clinical applications, 1(5), 467-75. https://doi.org/10.1002/prca.200600949
Chang, Kuo-Hsuan, et al. "Elevated haptoglobin level of cerebrospinal fluid in Guillain-Barré syndrome revealed by proteomics analysis." Proteomics. Clinical applications vol. 1,5 (2007): 467-75. doi: https://doi.org/10.1002/prca.200600949
Chang KH, Lyu RK, Tseng MY, Ro LS, Wu YR, Chang HS, Hsu WC, Kuo HC, Huang CC, Chu CC, Hsieh SY, Chen CM. Elevated haptoglobin level of cerebrospinal fluid in Guillain-Barré syndrome revealed by proteomics analysis. Proteomics Clin Appl. 2007 May;1(5):467-75. doi: 10.1002/prca.200600949. Epub 2007 Apr 19. PMID: 21136698.
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Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

Ratner P, Andrews CP, Hampel FC, Martin B, Mohar DE, Bourrelly D, Danaietash P, Mangialaio S, Dingemanse J, Hmissi A, van Bavel J.
PMID: 28392807
Allergy Asthma Clin Immunol. 2017 Apr 04;13:18. doi: 10.1186/s13223-017-0183-z. eCollection 2017.

BACKGROUND: Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present findings on the efficacy and safety/tolerability of a CRTH2 antagonist (setipiprant) in...

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Ratner P, Andrews CP, Hampel FC, et al. Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies. Allergy Asthma Clin Immunol. 2017;13:18doi: 10.1186/s13223-017-0183-z.
Ratner, P., Andrews, C. P., Hampel, F. C., Martin, B., Mohar, D. E., Bourrelly, D., Danaietash, P., Mangialaio, S., Dingemanse, J., Hmissi, A., & van Bavel, J. (2017). Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 1318. https://doi.org/10.1186/s13223-017-0183-z
Ratner, Paul, et al. "Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies." Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology vol. 13 (2017): 18. doi: https://doi.org/10.1186/s13223-017-0183-z
Ratner P, Andrews CP, Hampel FC, Martin B, Mohar DE, Bourrelly D, Danaietash P, Mangialaio S, Dingemanse J, Hmissi A, van Bavel J. Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies. Allergy Asthma Clin Immunol. 2017 Apr 04;13:18. doi: 10.1186/s13223-017-0183-z. eCollection 2017. PMID: 28392807; PMCID: PMC5379543.
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Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells.

PPAR research

Malaviya A, Sylvester PW.
PMID: 24729783
PPAR Res. 2014;2014:439146. doi: 10.1155/2014/439146. Epub 2014 Mar 04.

Previous findings showed that the anticancer effects of combined γ -tocotrienol and peroxisome proliferator activated receptor γ (PPAR γ ) antagonist treatment caused a large reduction in PPAR γ expression. However, other studies suggest that the antiproliferative effects of...

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Malaviya A, Sylvester PW. Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146doi: 10.1155/2014/439146.
Malaviya, A., & Sylvester, P. W. (2014). Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells. PPAR research, 2014439146. https://doi.org/10.1155/2014/439146
Malaviya, Abhita, and Sylvester, Paul W. "Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells." PPAR research vol. 2014 (2014): 439146. doi: https://doi.org/10.1155/2014/439146
Malaviya A, Sylvester PW. Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146. doi: 10.1155/2014/439146. Epub 2014 Mar 04. PMID: 24729783; PMCID: PMC3960771.
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Showing 13 to 24 of 90 entries