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Showing 25 to 36 of 299 entries
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Binding of transcription factor sp1 to exon-1 of C-myc is altered in burkitts-lymphoma.

International journal of oncology

Bryans M, Lucas J, Wilkie N, Burrow K, Clark A, Lang J.
PMID: 21584528
Int J Oncol. 1992 Jul;1(2):175-80. doi: 10.3892/ijo.1.2.175.

In Burkitt's lymphoma (BL) a consistent chromosomal translocation involving the c-myc proto-oncogene locus on chromosome 8 and one of the immunoglobulin loci located on chromosomes 14, 22 or 2 results in the aberrant expression of c-myc. In six out...

Delivery of health care in the far north.

Canadian family physician Medecin de famille canadien

Bryans AM.
PMID: 20468329
Can Fam Physician. 1968 Dec;14(12):55-61.

No abstract available.

Contract sterilization and validation companies offer new options for sterile compounded preparations.

International journal of pharmaceutical compounding

Latta KS, Howard B, Gordon K, Foster L, Nichols L, Floyd DB, Winters M, Bryans T.
PMID: 23970003
Int J Pharm Compd. 2009 Mar-Apr;13(2):106-19.

To ensure patient safety, adhere to good compounding practices, and safeguard against professional liability, the sterility of some compounded preparations must be assured. When in-house sterilization capabilities do not suffice, the intervention of a contract sterilization and/or validation company...

Pd-catalyzed allylic alkylation cascade with dihydropyrans: regioselective synthesis of furo[3,2-c]pyrans.

Organic letters

Bartlett MJ, Turner CA, Harvey JE.
PMID: 23621816
Org Lett. 2013 May 17;15(10):2430-3. doi: 10.1021/ol400902d. Epub 2013 Apr 26.

A regioselective palladium-catalyzed allylic alkylation cascade forms furo[3,2-c]pyrans from various cyclic β-dicarbonyl bis-nucleophiles and 3,6-dihydro-2H-pyran bis-electrophiles. The combination of allylic carbonate and anomeric siloxy leaving groups in the dihydropyran substrate allows control of the many regiochemical possibilities in this...

Academia-industry partnerships in drug discovery.

Expert opinion on drug discovery

Dalrymple M, Taylor D, Kettleborough C, Bryans J, Solari R.
PMID: 23506026
Expert Opin Drug Discov. 2006 Jun;1(1):1-6. doi: 10.1517/17460441.1.1.1.

The movement of ideas and innovation from academia into the world of business has a long and fruitful history. Ironically, it might be argued that the recent pressure put on universities and basic research organisations to protect and exploit...

Oxidative Prins and Prins/Friedel-Crafts cyclizations for the stereoselective synthesis of dioxabicycles and hexahydro-1H-benzo[f]isochromenes via the benzylic C-H activation.

Organic & biomolecular chemistry

Reddy BV, Borkar P, Yadav JS, Reddy PP, Kunwar AC, Sridhar B, Grée R.
PMID: 22187046
Org Biomol Chem. 2012 Feb 21;10(7):1349-58. doi: 10.1039/c1ob06489d. Epub 2011 Dec 20.

1-Benzyl ethers of (E)- and (Z)-hex-3-en-1,6-diols and hept-3-en-1,7-diols undergo a smooth oxidative cyclization with DDQ in the presence of In(OTf)(3) through a sequential C-H bond activation and an intramolecular Prins cyclization to afford the corresponding trans- and cis-fused hexahydro-2H-furo[3,2-c]pyrans...

Stress-induced cardiomyopathy: a syndrome of the susceptible patient?.

Expert review of cardiovascular therapy

Friedrich MG, Cocker MS.
PMID: 22390796
Expert Rev Cardiovasc Ther. 2012 Mar;10(3):271-3. doi: 10.1586/erc.12.9.

No abstract available.

Regio- and diastereoselective stepwise [8 + 3]-Cycloaddition reaction between tropone derivatives and donor-acceptor cyclopropanes.

Organic letters

Rivero AR, Fernández I, Sierra MÁ.
PMID: 24040858
Org Lett. 2013 Oct 04;15(19):4928-31. doi: 10.1021/ol4020656. Epub 2013 Sep 16.

A novel SnCl4-catalyzed [8 + 3]-cycloaddition reaction between tropone derivatives and donor-acceptor aminocyclopropanes is described. The process leads to the formation of amino-substituted tetrahydrocyclohepta[b]pyrans with complete regio- and diastereoselectivity. Density functional theory calculations suggest that the cycloaddition occurs stepwise...

X-ray-absorption study of rhenium L3 and L1 edges in ReO3: Multiple-scattering approach.

Physical review. B, Condensed matter

Benfatto M, Kuzmin A, Natoli CR, Purans J.
PMID: 10006298
Phys Rev B Condens Matter. 1993 Feb 01;47(5):2480-2486. doi: 10.1103/physrevb.47.2480.

No abstract available.

X-ray-absorption spectroscopy of Nd3+-exchanged beta -alumina crystal.

Physical review. B, Condensed matter

Kuzmin A, Mariotto G, Purans J, Rocca F.
PMID: 9982762
Phys Rev B Condens Matter. 1996 May 01;53(17):11444-11450. doi: 10.1103/physrevb.53.11444.

No abstract available.

Analysis of the Expression of Repetitive DNA Elements in Osteosarcoma.

Frontiers in genetics

Ho XD, Nguyen HG, Trinh LH, Reimann E, Prans E, Kõks G, Maasalu K, Le VQ, Nguyen VH, Le NTN, Phung P, Märtson A, Lattekivi F, Kõks S.
PMID: 29250102
Front Genet. 2017 Nov 30;8:193. doi: 10.3389/fgene.2017.00193. eCollection 2017.

Osteosarcoma (OS) is a rare malignant bone tumor. It affects mostly young persons and has poor outcome with the present treatment. No improvement was observed since the introduction of chemotherapy. The better understanding of osteosarcoma development could indicate better...

Total Synthesis of Bryostatin 8 Using an Organosilane-Based Strategy.

Angewandte Chemie (International ed. in English)

Zhang Y, Guo Q, Sun X, Lu J, Cao Y, Pu Q, Chu Z, Gao L, Song Z.
PMID: 29210495
Angew Chem Int Ed Engl. 2018 Jan 22;57(4):942-946. doi: 10.1002/anie.201711452. Epub 2017 Dec 20.

Convergent total synthesis of bryostatin 8 has been accomplished by an organosilane-based strategy. The C ring is constructed stereoselectively through a geminal bis(silane)-based [1,5]-Brook rearrangement, and the B ring through geminal bis(silane)-based Prins cyclization, thus efficiently joining the northern...

Showing 25 to 36 of 299 entries