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Showing 13 to 21 of 21 entries
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Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form.

Indian journal of pharmaceutical sciences

Bhavar GB, Chatpalliwar VA, Patil DD, Surana SJ.
PMID: 20046789
Indian J Pharm Sci. 2008 Jul-Aug;70(4):529-31. doi: 10.4103/0250-474X.44612.

Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F(254) plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements...

Efficacy and Safety of Quinapril 40mg Once Daily as Monotherapy for Patients with Poorly Controlled Hypertension : The EUREKA Study.

Clinical drug investigation

Pueyo C, Diaz C, Sol JM, Masramon X, Hernández G.
PMID: 23315349
Clin Drug Investig. 2000;20(2):81-8. doi: 10.2165/00044011-200020020-00002.

OBJECTIVE: We assessed the efficacy and safety of quinapril 40mg once daily for treating essential hypertension in patients with poorly controlled hypertension who were using other angiotensin-converting enzyme (ACE) inhibitors, or in those who needed to take more than...

Effect of Quinapril on the Circadian Blood Pressure Pattern Evaluated by Periodic Analysis of Covariance.

American journal of therapeutics

Hayashi H, Ohsugi S, Ishihara M, Kamiya H, Inden K, Suzuki A, Itoh A.
PMID: 11850656
Am J Ther. 1995 Apr;2(4):243-249. doi: 10.1097/00045391-199504000-00004.

The effects of quinapril on casual blood pressure (BP) and circadian variations in 24-h blood pressure (24ABPM) were studied in patients with essential hypertension. Twenty-six patients were enrolled in the study (mean age 59 plus minus 11 years). After...

Endothelial Vascular Function in Hypertensive Patients After Renin-Angiotensin System Blockad.

Journal of clinical hypertension (Greenwich, Conn.)

Souza-Barbosa LA, Ferreira-Melo SLE, Ubaid-Girioli S, Nogueira EA, Yugar-Toledo JC, Moreno H.
PMID: 29024440
J Clin Hypertens (Greenwich). 2006 Nov;8(11):803-811. doi: 10.1111/j.1524-6175.2006.05663.x.

It is unclear whether single and combined pharmacologic inhibition of the renin-angiotensin-aldosterone system have similar effects on endothelial function and blood pressure (BP). The authors evaluated 63 hypertensive patients divided into 4 groups (hydrochlorothiazide 25 mg/d; irbesartan [IRBE] 150...

Comparison of the cytotoxicity of ACE inhibitors and effects of cytochrome P-450 and glutathione modulation in primary rat hepatocyte cultures.

Toxicology in vitro : an international journal published in association with BIBRA

Jurima-Romet M, Huang HS.
PMID: 20692951
Toxicol In Vitro. 1994 Aug;8(4):529-31. doi: 10.1016/0887-2333(94)90007-8.

Hepatotoxicity has been reported with angiotensin-converting enzyme (ACE) inhibitors. The mechanism of liver injury is not known. In the present study, primary rat hepatocytes were used to investigate the cytotoxicity of ACE inhibitors. Captopril, enalapril, fosinopril and quinapril were...

Ion Pair-HPLC Method for the Simultaneous Estimation of Quinapril and Hydrochlorothiazide in Tablets.

Indian journal of pharmaceutical sciences

Gandhimathi M, Ravi TK.
PMID: 20490301
Indian J Pharm Sci. 2009 May;71(3):311-3. doi: 10.4103/0250-474X.56035.

A simple, precise and rapid HPLC method has been developed and validated for the estimation of quinapril and hydrochlorothiazide simultaneously in combined dosage form. The mobile phase used was a mixture of 0.1% v/v triethylamine (pH 3.5), containing 1...

The effects of antihypertensive drugs on the autonomic nervous system in elderly hypertensive patients with silent myocardial ischemia.

Archives of gerontology and geriatrics

Piccirillo G, Bucca C, Santagada E, Monteforte G, Viola E, Durante M, Munizzi MR, Tarantini S, Cacciafesta M, Marigliano V.
PMID: 18653018
Arch Gerontol Geriatr. 1996;22:119-24. doi: 10.1016/0167-4943(96)86923-8.

To seek further evidence for the participation of sympathetic nervous system in the onset of transient episodes of painless ischemia, we compared the behavior of the autonomic nervous system by means of power spectrum analysis of heart rate variability...

Binder jetting 3D printing of challenging medicines: from low dose tablets to hydrophobic molecules.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Kozakiewicz M, Nartowski KP, Dominik A, Malec K, Gołkowska AM, Złocińska A, Rusińska M, Szymczyk-Ziółkowska P, Ziółkowski G, Górniak A, Karolewicz B.
PMID: 34785345
Eur J Pharm Biopharm. 2021 Nov 13; doi: 10.1016/j.ejpb.2021.11.001. Epub 2021 Nov 13.

Increasing access to additive manufacturing technologies utilising easily available desktop devices opened novel ways for formulation of personalized medicines. It is, however, challenging to propose a flexible and robust formulation platform which can be used for fabrication of tailored...

Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Kozakiewicz-Latała M, Nartowski KP, Dominik A, Malec K, Gołkowska AM, Złocińska A, Rusińska M, Szymczyk-Ziółkowska P, Ziółkowski G, Górniak A, Karolewicz B.
PMID: 34785345
Eur J Pharm Biopharm. 2022 Jan;170:144-159. doi: 10.1016/j.ejpb.2021.11.001. Epub 2021 Nov 13.

Increasing access to additive manufacturing technologies utilising easily available desktop devices opened novel ways for formulation of personalized medicines. It is, however, challenging to propose a flexible and robust formulation platform which can be used for fabrication of tailored...

Showing 13 to 21 of 21 entries