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Showing 13 to 19 of 19 entries
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Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Human genomics

Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY.
PMID: 31092297
Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7.

BACKGROUND: End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease...

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Guan M, Keaton JM, Dimitrov L, et al. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019;13(1):21doi: 10.1186/s40246-019-0205-7.
Guan, M., Keaton, J. M., Dimitrov, L., Hicks, P. J., Xu, J., Palmer, N. D., Ma, L., Das, S. K., Chen, Y. I., Coresh, J., Fornage, M., Franceschini, N., Kramer, H., Langefeld, C. D., Mychaleckyj, J. C., Parekh, R. S., Post, W. S., Rasmussen-Torvik, L. J., Rich, S. S., Rotter, J. I., Sedor, J. R., Thornley-Brown, D., Tin, A., Wilson, J. G., Freedman, B. I., Bowden, D. W., Ng, M. C. Y. (2019). Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human genomics, 13(1), 21. https://doi.org/10.1186/s40246-019-0205-7
Guan, Meijian, et al. "Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Human genomics vol. 13,1 (2019): 21. doi: https://doi.org/10.1186/s40246-019-0205-7
Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7. PMID: 31092297; PMCID: PMC6521376.
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Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.

Circulation. Genomic and precision medicine

Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP.
PMID: 34706549
Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. Epub 2021 Oct 28.

BACKGROUND: suPAR (Soluble urokinase plasminogen activator receptor) has emerged as an important biomarker of coagulation, inflammation, and cardiovascular disease (CVD) risk. The contribution of suPAR to CVD risk and its genetic influence in Black populations have not been evaluated.METHODS:...

Cite
Olson NC, Raffield LM, Moxley AH, et al. Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circ Genom Precis Med. 2021;14(6):e003421doi: 10.1161/CIRCGEN.121.003421.
Olson, N. C., Raffield, L. M., Moxley, A. H., Miller-Fleming, T. W., Auer, P. L., Franceschini, N., Ngo, D., Thornton, T. A., Lange, E. M., Li, Y., Nickerson, D. A., Zakai, N. A., Gerszten, R. E., Cox, N. J., Correa, A., Mohlke, K. L., & Reiner, A. P. (2021). Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circulation. Genomic and precision medicine, 14(6), e003421. https://doi.org/10.1161/CIRCGEN.121.003421
Olson, Nels C, et al. "Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults." Circulation. Genomic and precision medicine vol. 14,6 (2021): e003421. doi: https://doi.org/10.1161/CIRCGEN.121.003421
Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP. Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. Epub 2021 Oct 28. PMID: 34706549; PMCID: PMC8692389.
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Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.

International journal of epidemiology

Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR.
PMID: 34999880
Int J Epidemiol. 2022 Jan 06;50(6):1995-2010. doi: 10.1093/ije/dyab203.

BACKGROUND: This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization.METHODS: A total of 45 risk factors with genetic...

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Zheng J, Zhang Y, Rasheed H, et al. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol. 2022;50(6):1995-2010doi: 10.1093/ije/dyab203.
Zheng, J., Zhang, Y., Rasheed, H., Walker, V., Sugawara, Y., Li, J., Leng, Y., Elsworth, B., Wootton, R. E., Fang, S., Yang, Q., Burgess, S., Haycock, P. C., Borges, M. C., Cho, Y., Carnegie, R., Howell, A., Robinson, J., Thomas, L. F., Brumpton, B. M., Hveem, K., Hallan, S., Franceschini, N., Morris, A. P., Köttgen, A., Pattaro, C., Wuttke, M., Yamamoto, M., Kashihara, N., Akiyama, M., Kanai, M., Matsuda, K., Kamatani, Y., Okada, Y., Walters, R., Millwood, I. Y., Chen, Z., Davey Smith, G., Barbour, S., Yu, C., Åsvold, B. O., Zhang, H., & Gaunt, T. R. (2022). Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. International journal of epidemiology, 50(6), 1995-2010. https://doi.org/10.1093/ije/dyab203
Zheng, Jie, et al. "Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease." International journal of epidemiology vol. 50,6 (2022): 1995-2010. doi: https://doi.org/10.1093/ije/dyab203
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol. 2022 Jan 06;50(6):1995-2010. doi: 10.1093/ije/dyab203. PMID: 34999880.
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Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States.

Journal of the American Society of Nephrology : JASN

Horimoto ARVR, Xue D, Cai J, Lash JP, Daviglus ML, Franceschini N, Thornton TA.
PMID: 34670813
J Am Soc Nephrol. 2022 Jan;33(1):77-87. doi: 10.1681/ASN.2021050617. Epub 2021 Oct 20.

BACKGROUND: Admixture mapping is a powerful approach for gene mapping of complex traits that leverages the diverse genetic ancestry in populations with recent admixture, such as Hispanic or Latino individuals in the United States. These individuals have an increased...

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Horimoto ARVR, Xue D, Cai J, et al. Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. J Am Soc Nephrol. 2021;33(1):77-87doi: 10.1681/ASN.2021050617.
Horimoto, A. R. V. R., Xue, D., Cai, J., Lash, J. P., Daviglus, M. L., Franceschini, N., & Thornton, T. A. (2022). Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. Journal of the American Society of Nephrology : JASN, 33(1), 77-87. https://doi.org/10.1681/ASN.2021050617
Horimoto, Andrea R V R, et al. "Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States." Journal of the American Society of Nephrology : JASN vol. 33,1 (2022): 77-87. doi: https://doi.org/10.1681/ASN.2021050617
Horimoto ARVR, Xue D, Cai J, Lash JP, Daviglus ML, Franceschini N, Thornton TA. Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. J Am Soc Nephrol. 2022 Jan;33(1):77-87. doi: 10.1681/ASN.2021050617. Epub 2021 Oct 20. PMID: 34670813.
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Metabolome-wide association study of estimated glomerular filtration rates in Hispanics.

Kidney international

Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N.
PMID: 34774559
Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10.

Circulating metabolites are by-products of endogenous metabolism or exogenous sources and may inform disease states. Our study aimed to identify the source of variability in the association of metabolites with estimated glomerular filtration rate (eGFR) in Hispanics/Latinos with low...

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Lin BM, Zhang Y, Yu B, et al. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2021;101(1):144-151doi: 10.1016/j.kint.2021.09.032.
Lin, B. M., Zhang, Y., Yu, B., Boerwinkle, E., Thygarajan, B., Yunes, M., Daviglus, M. L., Qi, Q., Kaplan, R., Lash, J., Cai, J., Sofer, T., & Franceschini, N. (2022). Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney international, 101(1), 144-151. https://doi.org/10.1016/j.kint.2021.09.032
Lin, Bridget M, et al. "Metabolome-wide association study of estimated glomerular filtration rates in Hispanics." Kidney international vol. 101,1 (2022): 144-151. doi: https://doi.org/10.1016/j.kint.2021.09.032
Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10. PMID: 34774559.
Copy Download .nbib Format: NLM
Metabolome-wide association study of estimated glomerular filtration rates in Hispanics.

Kidney international

Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N.
PMID: 34774559
Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10.

Circulating metabolites are by-products of endogenous metabolism or exogenous sources and may inform disease states. Our study aimed to identify the source of variability in the association of metabolites with estimated glomerular filtration rate (eGFR) in Hispanics/Latinos with low...

Cite
Lin BM, Zhang Y, Yu B, et al. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2021;101(1):144-151doi: 10.1016/j.kint.2021.09.032.
Lin, B. M., Zhang, Y., Yu, B., Boerwinkle, E., Thygarajan, B., Yunes, M., Daviglus, M. L., Qi, Q., Kaplan, R., Lash, J., Cai, J., Sofer, T., & Franceschini, N. (2022). Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney international, 101(1), 144-151. https://doi.org/10.1016/j.kint.2021.09.032
Lin, Bridget M, et al. "Metabolome-wide association study of estimated glomerular filtration rates in Hispanics." Kidney international vol. 101,1 (2022): 144-151. doi: https://doi.org/10.1016/j.kint.2021.09.032
Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10. PMID: 34774559; PMCID: PMC8741745.
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Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.

Circulation. Genomic and precision medicine

Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP.
PMID: 34706549
Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. Epub 2021 Oct 28.

BACKGROUND: suPAR (Soluble urokinase plasminogen activator receptor) has emerged as an important biomarker of coagulation, inflammation, and cardiovascular disease (CVD) risk. The contribution of suPAR to CVD risk and its genetic influence in Black populations have not been evaluated.METHODS:...

Cite
Olson NC, Raffield LM, Moxley AH, et al. Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circ Genom Precis Med. 2021;14(6):e003421doi: 10.1161/CIRCGEN.121.003421.
Olson, N. C., Raffield, L. M., Moxley, A. H., Miller-Fleming, T. W., Auer, P. L., Franceschini, N., Ngo, D., Thornton, T. A., Lange, E. M., Li, Y., Nickerson, D. A., Zakai, N. A., Gerszten, R. E., Cox, N. J., Correa, A., Mohlke, K. L., & Reiner, A. P. (2021). Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circulation. Genomic and precision medicine, 14(6), e003421. https://doi.org/10.1161/CIRCGEN.121.003421
Olson, Nels C, et al. "Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults." Circulation. Genomic and precision medicine vol. 14,6 (2021): e003421. doi: https://doi.org/10.1161/CIRCGEN.121.003421
Olson NC, Raffield LM, Moxley AH, Miller-Fleming TW, Auer PL, Franceschini N, Ngo D, Thornton TA, Lange EM, Li Y, Nickerson DA, Zakai NA, Gerszten RE, Cox NJ, Correa A, Mohlke KL, Reiner AP. Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults. Circ Genom Precis Med. 2021 Dec;14(6):e003421. doi: 10.1161/CIRCGEN.121.003421. Epub 2021 Oct 28. PMID: 34706549; PMCID: PMC8692389.
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Showing 13 to 19 of 19 entries