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Showing 25 to 28 of 28 entries
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RNA transfer through tunneling nanotubes.

Biochemical Society transactions

Haimovich G, Dasgupta S, Gerst JE.
PMID: 33367488
Biochem Soc Trans. 2021 Feb 26;49(1):145-160. doi: 10.1042/BST20200113.

It was already suggested in the early '70's that RNA molecules might transfer between mammalian cells in culture. Yet, more direct evidence for RNA transfer in animal and plant cells was only provided decades later, as this field became...

Uptake of platelets by cancer cells and recycling of the platelet protein CD42a.

Journal of thrombosis and haemostasis : JTH

Martins Castanheira N, Spanhofer AK, Wiener S, Bobe S, Schillers H.
PMID: 34592045
J Thromb Haemost. 2021 Sep 30; doi: 10.1111/jth.15543. Epub 2021 Sep 30.

BACKGROUND: It is well accepted that the bidirectional crosstalk between platelets and cancer cells promotes tumorigenesis and metastasis. In an early step, cancer cells trigger platelet granule and extracellular vesicle release that is needed to facilitate cancer cell survival...

Exogenous RNA as a Regulatory Signal during a Plant's Interaction with the Biotic Environment: An Evolutionary Perspective and Future Applications in Agriculture.

Plants (Basel, Switzerland)

Ivashuta S, Iandolino A, Watson G.
PMID: 33808982
Plants (Basel). 2021 Mar 12;10(3). doi: 10.3390/plants10030532.

Environmental RNAi (eRNAi) is a sequence-specific regulation of endogenous gene expression in a responsive organism by exogenous RNA. While exogenous RNA transfer between organisms of different kingdoms of life have been unambiguously identified in nature, our understanding of the...

Platelets and tumor-associated RNA transfer.

Blood

D'Ambrosi S, Nilsson RJ, Wurdinger T.
PMID: 33940602
Blood. 2021 Jun 10;137(23):3181-3191. doi: 10.1182/blood.2019003978.

Until recently, the nucleic acid content of platelets was considered to be fully determined by their progenitor megakaryocyte. However, it is now well understood that additional mediators (eg, cancer cells) can intervene, thereby influencing the RNA repertoire of platelets....

Showing 25 to 28 of 28 entries