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Showing 9985 to 9996 of 117006 entries
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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.

Gut

Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Melo CA, Castaldo SA, Campos-Laborie F, Moutinho-Ribeiro P, Morão B, Costa-Pinto A, Silva S, Osorio H, Ciordia S, Costa JL, Goodrich D, Cavadas B, Pereira L, Kouzarides T, Macedo G, Maio R, Carneiro F, Cravo M, Kalluri R, Machado JC, Melo SA.
PMID: 35012996
Gut. 2022 Jan 10; doi: 10.1136/gutjnl-2021-324994. Epub 2022 Jan 10.

OBJECTIVE: Intratumor heterogeneity drives cancer progression and therapy resistance. However, it has yet to be determined whether and how subpopulations of cancer cells interact and how this interaction affects the tumour.DESIGN: We have studied the spontaneous flow of extracellular...

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Ruivo CF, Bastos N, Adem B, et al. Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. Gut. 2022;doi: 10.1136/gutjnl-2021-324994.
Ruivo, C. F., Bastos, N., Adem, B., Batista, I., Duraes, C., Melo, C. A., Castaldo, S. A., Campos-Laborie, F., Moutinho-Ribeiro, P., Morão, B., Costa-Pinto, A., Silva, S., Osorio, H., Ciordia, S., Costa, J. L., Goodrich, D., Cavadas, B., Pereira, L., Kouzarides, T., Macedo, G., Maio, R., Carneiro, F., Cravo, M., Kalluri, R., Machado, J. C., & Melo, S. A. (2022). Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. Gut, . https://doi.org/10.1136/gutjnl-2021-324994
Ruivo, Carolina F, et al. "Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression." Gut vol. (2022). doi: https://doi.org/10.1136/gutjnl-2021-324994
Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Melo CA, Castaldo SA, Campos-Laborie F, Moutinho-Ribeiro P, Morão B, Costa-Pinto A, Silva S, Osorio H, Ciordia S, Costa JL, Goodrich D, Cavadas B, Pereira L, Kouzarides T, Macedo G, Maio R, Carneiro F, Cravo M, Kalluri R, Machado JC, Melo SA. Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. Gut. 2022 Jan 10; doi: 10.1136/gutjnl-2021-324994. Epub 2022 Jan 10. PMID: 35012996.
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PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner.

Cancer immunology research

Zhou M, Leung JY, Gessner KH, Hepperla AJ, Simon JM, Davis IJ, Kim WY.
PMID: 35013001
Cancer Immunol Res. 2022 Jan 10; doi: 10.1158/2326-6066.CIR-21-0480. Epub 2022 Jan 10.

Clear cell renal cell carcinoma (ccRCC) is considered an immunotherapy-responsive disease; however, the reasons for this remain unclear. Studies have variably implicated PBRM1 mutations as a predictive biomarker of immune checkpoint blockade (ICB) response, and separate studies demonstrate that...

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Zhou M, Leung JY, Gessner KH, et al. PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner. Cancer Immunol Res. 2022;doi: 10.1158/2326-6066.CIR-21-0480.
Zhou, M., Leung, J. Y., Gessner, K. H., Hepperla, A. J., Simon, J. M., Davis, I. J., & Kim, W. Y. (2022). PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner. Cancer immunology research, . https://doi.org/10.1158/2326-6066.CIR-21-0480
Zhou, Mi, et al. "PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner." Cancer immunology research vol. (2022). doi: https://doi.org/10.1158/2326-6066.CIR-21-0480
Zhou M, Leung JY, Gessner KH, Hepperla AJ, Simon JM, Davis IJ, Kim WY. PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner. Cancer Immunol Res. 2022 Jan 10; doi: 10.1158/2326-6066.CIR-21-0480. Epub 2022 Jan 10. PMID: 35013001.
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Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Zia Ur Rehman R, Rochester L, Yarnall AJ, Del Din S.
PMID: 34891283
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:249-252. doi: 10.1109/EMBC46164.2021.9630769.

Parkinson's disease (PD) is a common neurodegenerative disease presenting with both motor and non-motor symptoms. Among PD motor symptoms, gait impairments are common and evolve over time. PD motor symptoms severity can be evaluated using clinical scales such as...

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Zia Ur Rehman R, Rochester L, Yarnall AJ, et al. Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning. Annu Int Conf IEEE Eng Med Biol Soc. 2021;2021:249-252doi: 10.1109/EMBC46164.2021.9630769.
Zia Ur Rehman, R., Rochester, L., Yarnall, A. J., & Del Din, S. (2021). Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021249-252. https://doi.org/10.1109/EMBC46164.2021.9630769
Zia Ur Rehman, Rana, et al. "Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning." Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference vol. 2021 (2021): 249-252. doi: https://doi.org/10.1109/EMBC46164.2021.9630769
Zia Ur Rehman R, Rochester L, Yarnall AJ, Del Din S. Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning. Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:249-252. doi: 10.1109/EMBC46164.2021.9630769. PMID: 34891283.
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Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer.

Current molecular medicine

Hamid UZ, Sim MS, Guad RM, Subramaniyan V, Sekar M, Fuloria NK, Fuloria S, Choy KW, Fareez IM, Bonam SR, Wu YS.
PMID: 34365949
Curr Mol Med. 2021 Aug 06; doi: 10.2174/1566524021666210806162848. Epub 2021 Aug 06.

Gastrointestinal (GI) cancers presented an alarmingly high number of new cancer cases worldwide and highly characterised with poor prognosis. The poor overall survival is mainly due to late detection and emerging challenges in treatment, particularly chemoresistance. Thus, the identification...

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Hamid UZ, Sim MS, Guad RM, et al. Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer. Curr Mol Med. 2021;doi: 10.2174/1566524021666210806162848.
Hamid, U. Z., Sim, M. S., Guad, R. M., Subramaniyan, V., Sekar, M., Fuloria, N. K., Fuloria, S., Choy, K. W., Fareez, I. M., Bonam, S. R., & Wu, Y. S. (2021). Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer. Current molecular medicine, . https://doi.org/10.2174/1566524021666210806162848
Hamid, Ummi Zulaiqha, et al. "Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer." Current molecular medicine vol. (2021). doi: https://doi.org/10.2174/1566524021666210806162848
Hamid UZ, Sim MS, Guad RM, Subramaniyan V, Sekar M, Fuloria NK, Fuloria S, Choy KW, Fareez IM, Bonam SR, Wu YS. Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer. Curr Mol Med. 2021 Aug 06; doi: 10.2174/1566524021666210806162848. Epub 2021 Aug 06. PMID: 34365949.
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Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor.

Molecules (Basel, Switzerland)

López-López J, Tejeda-Ochoa A, López-Beltrán A, Herrera-Ramírez J, Méndez-Herrera P.
PMID: 35011237
Molecules. 2021 Dec 21;27(1). doi: 10.3390/molecules27010006.

In this work, the assessment of

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López-López J, Tejeda-Ochoa A, López-Beltrán A, et al. Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor. Molecules. 2021;27(1)doi: 10.3390/molecules27010006.
López-López, J., Tejeda-Ochoa, A., López-Beltrán, A., Herrera-Ramírez, J., & Méndez-Herrera, P. (2021). Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010006
López-López, Juan, et al. "Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor." Molecules (Basel, Switzerland) vol. 27,1 (2021). doi: https://doi.org/10.3390/molecules27010006
López-López J, Tejeda-Ochoa A, López-Beltrán A, Herrera-Ramírez J, Méndez-Herrera P. Sunlight Photocatalytic Performance of ZnO Nanoparticles Synthesized by Green Chemistry Using Different Botanical Extracts and Zinc Acetate as a Precursor. Molecules. 2021 Dec 21;27(1). doi: 10.3390/molecules27010006. PMID: 35011237.
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Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas.

Molecular cancer

Wang Y, Wu C, Du Y, Li Z, Li M, Hou P, Shen Z, Chu S, Zheng J, Bai J.
PMID: 34996480
Mol Cancer. 2022 Jan 07;21(1):13. doi: 10.1186/s12943-021-01484-7.

Circular RNAs (circRNAs) are classified as noncoding RNAs because they are devoid of a 5' end cap and a 3' end poly (A) tail necessary for cap-dependent translation. However, increasing numbers of translated circRNAs identified through high-throughput RNA sequencing...

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Wang Y, Wu C, Du Y, et al. Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas. Mol Cancer. 2022;21(1):13doi: 10.1186/s12943-021-01484-7.
Wang, Y., Wu, C., Du, Y., Li, Z., Li, M., Hou, P., Shen, Z., Chu, S., Zheng, J., & Bai, J. (2022). Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas. Molecular cancer, 21(1), 13. https://doi.org/10.1186/s12943-021-01484-7
Wang, Yan, et al. "Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas." Molecular cancer vol. 21,1 (2022): 13. doi: https://doi.org/10.1186/s12943-021-01484-7
Wang Y, Wu C, Du Y, Li Z, Li M, Hou P, Shen Z, Chu S, Zheng J, Bai J. Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas. Mol Cancer. 2022 Jan 07;21(1):13. doi: 10.1186/s12943-021-01484-7. PMID: 34996480; PMCID: PMC8740365.
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Over-activation of EFTUD2 correlates with tumor propagation and poor survival outcomes in hepatocellular carcinoma.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Lv C, Li XJ, Hao LX, Zhang S, Song Z, Ji XD, Gong B.
PMID: 34282556
Clin Transl Oncol. 2021 Jul 19; doi: 10.1007/s12094-021-02673-y. Epub 2021 Jul 19.

PURPOSE: Elongation factor Tu GTP-binding domain containing 2 (EFTUD2) is an essential constituent of U5 small nuclear ribonucleoproteins (snRNPs) and plays a crucial role in spliceosome activation and cancer. The mechanism of EFTUD2 on carcinogenesis and development of liver...

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Lv C, Li XJ, Hao LX, et al. Over-activation of EFTUD2 correlates with tumor propagation and poor survival outcomes in hepatocellular carcinoma. Clin Transl Oncol. 2021;doi: 10.1007/s12094-021-02673-y.
Lv, C., Li, X. J., Hao, L. X., Zhang, S., Song, Z., Ji, X. D., & Gong, B. (2021). Over-activation of EFTUD2 correlates with tumor propagation and poor survival outcomes in hepatocellular carcinoma. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, . https://doi.org/10.1007/s12094-021-02673-y
Lv, C, et al. "Over-activation of EFTUD2 correlates with tumor propagation and poor survival outcomes in hepatocellular carcinoma." Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico vol. (2021). doi: https://doi.org/10.1007/s12094-021-02673-y
Lv C, Li XJ, Hao LX, Zhang S, Song Z, Ji XD, Gong B. Over-activation of EFTUD2 correlates with tumor propagation and poor survival outcomes in hepatocellular carcinoma. Clin Transl Oncol. 2021 Jul 19; doi: 10.1007/s12094-021-02673-y. Epub 2021 Jul 19. PMID: 34282556.
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Unified Nanotechnology Format: One Way to Store Them All.

Molecules (Basel, Switzerland)

Kuťák D, Poppleton E, Miao H, Šulc P, Barišić I.
PMID: 35011301
Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010063.

The domains of DNA and RNA nanotechnology are steadily gaining in popularity while proving their value with various successful results, including biosensing robots and drug delivery cages. Nowadays, the nanotechnology design pipeline usually relies on computer-based design (CAD) approaches...

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Kuťák D, Poppleton E, Miao H, et al. Unified Nanotechnology Format: One Way to Store Them All. Molecules. 2021;27(1)doi: 10.3390/molecules27010063.
Kuťák, D., Poppleton, E., Miao, H., Šulc, P., & Barišić, I. (2021). Unified Nanotechnology Format: One Way to Store Them All. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010063
Kuťák, David, et al. "Unified Nanotechnology Format: One Way to Store Them All." Molecules (Basel, Switzerland) vol. 27,1 (2021). doi: https://doi.org/10.3390/molecules27010063
Kuťák D, Poppleton E, Miao H, Šulc P, Barišić I. Unified Nanotechnology Format: One Way to Store Them All. Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010063. PMID: 35011301.
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lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p.

Disease markers

Xia YC, Cao J, Yang J, Zhang Y, Li YS.
PMID: 34336002
Dis Markers. 2021 Jul 17;2021:2217663. doi: 10.1155/2021/2217663. eCollection 2021.

BACKGROUND: Long noncoding RNA (lncRNA) critically impacts the modulation of tumor developments and progressions. Our study is aimed at investigating the expressing patterns, clinical significance, and biological roles of lncRNA TSPEAR-AS2 (TSPEAR-AS2) in oral squamous cell carcinoma (OSCC). RESULTS:...

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Xia YC, Cao J, Yang J, et al. lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p. Dis Markers. 2021;2021:2217663doi: 10.1155/2021/2217663.
Xia, Y. C., Cao, J., Yang, J., Zhang, Y., & Li, Y. S. (2021). lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p. Disease markers, 20212217663. https://doi.org/10.1155/2021/2217663
Xia, Yi-Chao, et al. "lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p." Disease markers vol. 2021 (2021): 2217663. doi: https://doi.org/10.1155/2021/2217663
Xia YC, Cao J, Yang J, Zhang Y, Li YS. lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p. Dis Markers. 2021 Jul 17;2021:2217663. doi: 10.1155/2021/2217663. eCollection 2021. PMID: 34336002; PMCID: PMC8313349.
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Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population.

Hepatobiliary & pancreatic diseases international : HBPD INT

Guo XY, Xia YL, Li ZY, Li R, Fan Y, Yao WM, Liu F.
PMID: 34366198
Hepatobiliary Pancreat Dis Int. 2021 Jul 24; doi: 10.1016/j.hbpd.2021.07.001. Epub 2021 Jul 24.

BACKGROUND: Apoptosis, also called programmed cell death, is a genetically controlled process against hyperproliferation and malignancy. The Fas-Fas ligand (FasL) system is considered a major pathway for apoptosis in cells and tissues. Thus, this study aimed to investigate whether...

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Guo XY, Xia YL, Li ZY, et al. Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population. Hepatobiliary Pancreat Dis Int. 2021;doi: 10.1016/j.hbpd.2021.07.001.
Guo, X. Y., Xia, Y. L., Li, Z. Y., Li, R., Fan, Y., Yao, W. M., & Liu, F. (2021). Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population. Hepatobiliary & pancreatic diseases international : HBPD INT, . https://doi.org/10.1016/j.hbpd.2021.07.001
Guo, Xin-Yi, et al. "Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population." Hepatobiliary & pancreatic diseases international : HBPD INT vol. (2021). doi: https://doi.org/10.1016/j.hbpd.2021.07.001
Guo XY, Xia YL, Li ZY, Li R, Fan Y, Yao WM, Liu F. Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population. Hepatobiliary Pancreat Dis Int. 2021 Jul 24; doi: 10.1016/j.hbpd.2021.07.001. Epub 2021 Jul 24. PMID: 34366198.
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Targeted editing and evolution of engineered ribosomes in vivo by filtered editing.

Nature communications

Radford F, Elliott SD, Schepartz A, Isaacs FJ.
PMID: 35013328
Nat Commun. 2022 Jan 10;13(1):180. doi: 10.1038/s41467-021-27836-x.

Genome editing technologies introduce targeted chromosomal modifications in organisms yet are constrained by the inability to selectively modify repetitive genetic elements. Here we describe filtered editing, a genome editing method that embeds group 1 self-splicing introns into repetitive genetic...

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Radford F, Elliott SD, Schepartz A, et al. Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nat Commun. 2022;13(1):180doi: 10.1038/s41467-021-27836-x.
Radford, F., Elliott, S. D., Schepartz, A., & Isaacs, F. J. (2022). Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nature communications, 13(1), 180. https://doi.org/10.1038/s41467-021-27836-x
Radford, Felix, et al. "Targeted editing and evolution of engineered ribosomes in vivo by filtered editing." Nature communications vol. 13,1 (2022): 180. doi: https://doi.org/10.1038/s41467-021-27836-x
Radford F, Elliott SD, Schepartz A, Isaacs FJ. Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nat Commun. 2022 Jan 10;13(1):180. doi: 10.1038/s41467-021-27836-x. PMID: 35013328.
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Proton beam irradiation induces invisible modifications under the surface of painted parchment.

Scientific reports

Müller K, Szikszai Z, Csepregi Á, Huszánk R, Kertész Z, Reiche I.
PMID: 34996914
Sci Rep. 2022 Jan 07;12(1):113. doi: 10.1038/s41598-021-02993-7.

Ion beam analysis plays an important role in cultural heritage (CH) studies as it offers a combination of simultaneous and complementary analytical techniques (PIXE/PIGE/RBS) and spatially resolved mapping functions. Despite being considered non-destructive, the potential risk of beam-induced modifications...

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Müller K, Szikszai Z, Csepregi Á, et al. Proton beam irradiation induces invisible modifications under the surface of painted parchment. Sci Rep. 2022;12(1):113doi: 10.1038/s41598-021-02993-7.
Müller, K., Szikszai, Z., Csepregi, �. �., Huszánk, R., Kertész, Z., & Reiche, I. (2022). Proton beam irradiation induces invisible modifications under the surface of painted parchment. Scientific reports, 12(1), 113. https://doi.org/10.1038/s41598-021-02993-7
Müller, Katharina, et al. "Proton beam irradiation induces invisible modifications under the surface of painted parchment." Scientific reports vol. 12,1 (2022): 113. doi: https://doi.org/10.1038/s41598-021-02993-7
Müller K, Szikszai Z, Csepregi Á, Huszánk R, Kertész Z, Reiche I. Proton beam irradiation induces invisible modifications under the surface of painted parchment. Sci Rep. 2022 Jan 07;12(1):113. doi: 10.1038/s41598-021-02993-7. PMID: 34996914.
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Showing 9985 to 9996 of 117006 entries