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Showing 5665 to 5675 of 5675 entries
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Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy.

Frontiers in pharmacology

Chang M, Yang B, Li L, Si Y, Zhao M, Hao W, Zhao J, Zhang Y.
PMID: 34381367
Front Pharmacol. 2021 Jul 26;12:714584. doi: 10.3389/fphar.2021.714584. eCollection 2021.

Modified Huangqi Chifeng decoction (MHCD) has been used to reduce proteinuria in immunoglobulin A nephropathy (IgAN) for many years. Previously, we have demonstrated its protective role in glomerular mesangial cells. Podocyte injury, another key factor associated with proteinuria in...

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Chang M, Yang B, Li L, et al. Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy. Front Pharmacol. 2021;12:714584doi: 10.3389/fphar.2021.714584.
Chang, M., Yang, B., Li, L., Si, Y., Zhao, M., Hao, W., Zhao, J., & Zhang, Y. (2021). Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy. Frontiers in pharmacology, 12714584. https://doi.org/10.3389/fphar.2021.714584
Chang, Meiying, et al. "Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy." Frontiers in pharmacology vol. 12 (2021): 714584. doi: https://doi.org/10.3389/fphar.2021.714584
Chang M, Yang B, Li L, Si Y, Zhao M, Hao W, Zhao J, Zhang Y. Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy. Front Pharmacol. 2021 Jul 26;12:714584. doi: 10.3389/fphar.2021.714584. eCollection 2021. PMID: 34381367; PMCID: PMC8350133.
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HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole.

Journal of biomolecular structure & dynamics

Prasanthan P, Kishore N.
PMID: 34296662
J Biomol Struct Dyn. 2021 Jul 23;1-13. doi: 10.1080/07391102.2021.1953605. Epub 2021 Jul 23.

Protein-based nanoparticles offer a suitable targeted delivery platform to drugs in terms of biocompatibility, biodegradability and abundance in nature. Physicochemical understanding of drug encapsulation by protein nanoparticles and their impact on protein aggregation is essential. In this work, we...

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Prasanthan P, Kishore N. HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole. J Biomol Struct Dyn. 2021;1-13doi: 10.1080/07391102.2021.1953605.
Prasanthan, P., & Kishore, N. (2021). HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole. Journal of biomolecular structure & dynamics, 1-13. https://doi.org/10.1080/07391102.2021.1953605
Prasanthan, Pooja, and Kishore, Nand. "HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole." Journal of biomolecular structure & dynamics vol. (2021): 1-13. doi: https://doi.org/10.1080/07391102.2021.1953605
Prasanthan P, Kishore N. HSA nanoparticles in drug recognition: mechanistic insights with naproxen, diclofenac and methimazole. J Biomol Struct Dyn. 2021 Jul 23;1-13. doi: 10.1080/07391102.2021.1953605. Epub 2021 Jul 23. PMID: 34296662.
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The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy.

International journal of biological macromolecules

Mohammad Zakariya S, Zaman M, Nabi F, Moasfar Ali S, Jahan I, Nayeem SM, Khan RH.
PMID: 34973990
Int J Biol Macromol. 2021 Dec 30;199:181-188. doi: 10.1016/j.ijbiomac.2021.12.121. Epub 2021 Dec 30.

Intensive research in the field of protein aggregation confirmed that the deposition of amyloid fibrils of proteins are the major cause for the development of various neurotoxic and neurodegenerative diseases, which could be controlled by ensuring the efficient inhibition...

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Mohammad Zakariya S, Zaman M, Nabi F, et al. The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy. Int J Biol Macromol. 2021;199:181-188doi: 10.1016/j.ijbiomac.2021.12.121.
Mohammad Zakariya, S., Zaman, M., Nabi, F., Moasfar Ali, S., Jahan, I., Nayeem, S. M., & Khan, R. H. (2021). The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy. International journal of biological macromolecules, 199181-188. https://doi.org/10.1016/j.ijbiomac.2021.12.121
Mohammad Zakariya, Syed, et al. "The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy." International journal of biological macromolecules vol. 199 (2021): 181-188. doi: https://doi.org/10.1016/j.ijbiomac.2021.12.121
Mohammad Zakariya S, Zaman M, Nabi F, Moasfar Ali S, Jahan I, Nayeem SM, Khan RH. The inhibitory effect of Sunset Yellow on thermally induced Human Serum Albumin aggregates: Possible role in naturopathy. Int J Biol Macromol. 2021 Dec 30;199:181-188. doi: 10.1016/j.ijbiomac.2021.12.121. Epub 2021 Dec 30. PMID: 34973990.
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Fecal Calprotectin in Combination With Standard Blood Tests in the Diagnosis of Inflammatory Bowel Disease in Children.

Frontiers in pediatrics

Ho SSC, Ross M, Keenan JI, Day AS.
PMID: 33748035
Front Pediatr. 2021 Mar 05;8:609279. doi: 10.3389/fped.2020.609279. eCollection 2020.

No abstract available.

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Ho SSC, Ross M, Keenan JI, et al. Fecal Calprotectin in Combination With Standard Blood Tests in the Diagnosis of Inflammatory Bowel Disease in Children. Front Pediatr. 2021;8:609279doi: 10.3389/fped.2020.609279.
Ho, S. S. C., Ross, M., Keenan, J. I., & Day, A. S. (2020). Fecal Calprotectin in Combination With Standard Blood Tests in the Diagnosis of Inflammatory Bowel Disease in Children. Frontiers in pediatrics, 8609279. https://doi.org/10.3389/fped.2020.609279
Ho, Shaun S C, et al. "Fecal Calprotectin in Combination With Standard Blood Tests in the Diagnosis of Inflammatory Bowel Disease in Children." Frontiers in pediatrics vol. 8 (2020): 609279. doi: https://doi.org/10.3389/fped.2020.609279
Ho SSC, Ross M, Keenan JI, Day AS. Fecal Calprotectin in Combination With Standard Blood Tests in the Diagnosis of Inflammatory Bowel Disease in Children. Front Pediatr. 2021 Mar 05;8:609279. doi: 10.3389/fped.2020.609279. eCollection 2020. PMID: 33748035; PMCID: PMC7973106.
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Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS.

Journal of pharmaceutical and biomedical analysis

Qu M, Xue P, Zhang Q, Lu T, Liu K, Hu B, Pang J, Xiao Q, Xu T, Wang Q, Cheng Z.
PMID: 34979491
J Pharm Biomed Anal. 2021 Dec 24;210:114542. doi: 10.1016/j.jpba.2021.114542. Epub 2021 Dec 24.

Solasodine, a major ingredient in Solanaceae family, has various biological functions such as inducing neurogenesis, anticonvulsant and anti-tumor. Its risk assessment has also drawn public attention. However, little is known about its oral bioavailability and metabolic process. In this...

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Qu M, Xue P, Zhang Q, et al. Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS. J Pharm Biomed Anal. 2021;210:114542doi: 10.1016/j.jpba.2021.114542.
Qu, M., Xue, P., Zhang, Q., Lu, T., Liu, K., Hu, B., Pang, J., Xiao, Q., Xu, T., Wang, Q., & Cheng, Z. (2021). Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS. Journal of pharmaceutical and biomedical analysis, 210114542. https://doi.org/10.1016/j.jpba.2021.114542
Qu, Mei, et al. "Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS." Journal of pharmaceutical and biomedical analysis vol. 210 (2021): 114542. doi: https://doi.org/10.1016/j.jpba.2021.114542
Qu M, Xue P, Zhang Q, Lu T, Liu K, Hu B, Pang J, Xiao Q, Xu T, Wang Q, Cheng Z. Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS. J Pharm Biomed Anal. 2021 Dec 24;210:114542. doi: 10.1016/j.jpba.2021.114542. Epub 2021 Dec 24. PMID: 34979491.
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Design of Light-Activated Nanoplatform through Boosting "Eat Me" Signals for Improved CD47-Blocking Immunotherapy.

Advanced healthcare materials

Lu Y, Gong Y, Zhu X, Dong X, Zhu D, Ma G.
PMID: 34981660
Adv Healthc Mater. 2022 Jan 03;e2102712. doi: 10.1002/adhm.202102712. Epub 2022 Jan 03.

Here, the authors propose a light-activated reactive oxygen species (ROS)-responsive nanoplatform that can boost immunogenic cell death (ICD) to release "eat me" signals, and improve CD47-blocking immunotherapy by tumor-targeted codelivery of photosensitizer IR820 and anti-CD47 antibody (αCD47). Human serum...

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Lu Y, Gong Y, Zhu X, et al. Design of Light-Activated Nanoplatform through Boosting "Eat Me" Signals for Improved CD47-Blocking Immunotherapy. Adv Healthc Mater. 2022;e2102712doi: 10.1002/adhm.202102712.
Lu, Y., Gong, Y., Zhu, X., Dong, X., Zhu, D., & Ma, G. (2022). Design of Light-Activated Nanoplatform through Boosting "Eat Me" Signals for Improved CD47-Blocking Immunotherapy. Advanced healthcare materials, e2102712. https://doi.org/10.1002/adhm.202102712
Lu, Yan, et al. "Design of Light-Activated Nanoplatform through Boosting "Eat Me" Signals for Improved CD47-Blocking Immunotherapy." Advanced healthcare materials vol. (2022): e2102712. doi: https://doi.org/10.1002/adhm.202102712
Lu Y, Gong Y, Zhu X, Dong X, Zhu D, Ma G. Design of Light-Activated Nanoplatform through Boosting "Eat Me" Signals for Improved CD47-Blocking Immunotherapy. Adv Healthc Mater. 2022 Jan 03;e2102712. doi: 10.1002/adhm.202102712. Epub 2022 Jan 03. PMID: 34981660.
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Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A.

Journal of transplantation

Tang L, Azzi J, Kwon M, Mounayar M, Tong R, Yin Q, Moore R, Skartsis N, Fan TM, Abdi R, Cheng J.
PMID: 22545201
J Transplant. 2012;2012:896141. doi: 10.1155/2012/896141. Epub 2012 Mar 29.

We encapsulated cyclosporine A (CsA) in poly(ethylene glycol)-b-poly(d,l-lactide-co-glycolide) (PEG-PLGA) nanoparticles (NPs) by nanoprecipitation of CsA and PEG-PLGA. The resulting CsA/PEG-PLGA-NPs were

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Tang L, Azzi J, Kwon M, et al. Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A. J Transplant. 2012;2012:896141doi: 10.1155/2012/896141.
Tang, L., Azzi, J., Kwon, M., Mounayar, M., Tong, R., Yin, Q., Moore, R., Skartsis, N., Fan, T. M., Abdi, R., & Cheng, J. (2012). Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A. Journal of transplantation, 2012896141. https://doi.org/10.1155/2012/896141
Tang, Li, et al. "Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A." Journal of transplantation vol. 2012 (2012): 896141. doi: https://doi.org/10.1155/2012/896141
Tang L, Azzi J, Kwon M, Mounayar M, Tong R, Yin Q, Moore R, Skartsis N, Fan TM, Abdi R, Cheng J. Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A. J Transplant. 2012;2012:896141. doi: 10.1155/2012/896141. Epub 2012 Mar 29. PMID: 22545201; PMCID: PMC3321582.
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Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patients.

Burns : journal of the International Society for Burn Injuries

Wang B, Hu L, Chen Y, Zhu B, Kong W, Zhu Z, Wang K, Yu Q, Zhang W, Wu G, Sun Y, Xia Z.
PMID: 34456097
Burns. 2021 Aug 18; doi: 10.1016/j.burns.2021.08.006. Epub 2021 Aug 18.

BACKGROUND: Although treatment of burn patients has significantly improved in recent decades, major burns remain fatal. Therefore, the evaluation of the death risk of the patients with extensive burns is very important. The ratio between the serum levels of...

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Wang B, Hu L, Chen Y, et al. Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patients. Burns. 2021;doi: 10.1016/j.burns.2021.08.006.
Wang, B., Hu, L., Chen, Y., Zhu, B., Kong, W., Zhu, Z., Wang, K., Yu, Q., Zhang, W., Wu, G., Sun, Y., & Xia, Z. (2021). Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patients. Burns : journal of the International Society for Burn Injuries, . https://doi.org/10.1016/j.burns.2021.08.006
Wang, Baoli, et al. "Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patients." Burns : journal of the International Society for Burn Injuries vol. (2021). doi: https://doi.org/10.1016/j.burns.2021.08.006
Wang B, Hu L, Chen Y, Zhu B, Kong W, Zhu Z, Wang K, Yu Q, Zhang W, Wu G, Sun Y, Xia Z. Aspartate transaminase/alanine transaminase (De Ritis ratio) predicts survival in major burn patients. Burns. 2021 Aug 18; doi: 10.1016/j.burns.2021.08.006. Epub 2021 Aug 18. PMID: 34456097.
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Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules.

International journal of pharmaceutics

Weaver E, O'Connor E, Cole DK, Hooker A, Uddin S, Lamprou DA.
PMID: 34890709
Int J Pharm. 2021 Dec 07;611:121347. doi: 10.1016/j.ijpharm.2021.121347. Epub 2021 Dec 07.

The encapsulation of biologic molecules using a microfluidic platform is a procedure that has been understudied but shows great promise from initial reported studies. The study focusses upon the encapsulation of bovine serum albumin (BSA) under various parameters and...

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Weaver E, O'Connor E, Cole DK, et al. Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules. Int J Pharm. 2021;611:121347doi: 10.1016/j.ijpharm.2021.121347.
Weaver, E., O'Connor, E., Cole, D. K., Hooker, A., Uddin, S., & Lamprou, D. A. (2021). Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules. International journal of pharmaceutics, 611121347. https://doi.org/10.1016/j.ijpharm.2021.121347
Weaver, Edward, et al. "Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules." International journal of pharmaceutics vol. 611 (2021): 121347. doi: https://doi.org/10.1016/j.ijpharm.2021.121347
Weaver E, O'Connor E, Cole DK, Hooker A, Uddin S, Lamprou DA. Microfluidic-mediated self-assembly of phospholipids for the delivery of biologic molecules. Int J Pharm. 2021 Dec 07;611:121347. doi: 10.1016/j.ijpharm.2021.121347. Epub 2021 Dec 07. PMID: 34890709.
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Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19).

International journal of general medicine

Huang D, Yang H, Yu H, Wang T, Chen Z, Liang Z, Yao R.
PMID: 34456583
Int J Gen Med. 2021 Aug 21;14:4711-4721. doi: 10.2147/IJGM.S326204. eCollection 2021.

PURPOSE: We sought to explore the prognostic value of blood urea nitrogen (BUN) to serum albumin ratio (BAR) and further develop a prediction model for critical illness in COVID-19 patients.PATIENTS AND METHODS: This was a retrospective, multicenter, observational study...

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Huang D, Yang H, Yu H, et al. Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19). Int J Gen Med. 2021;14:4711-4721doi: 10.2147/IJGM.S326204.
Huang, D., Yang, H., Yu, H., Wang, T., Chen, Z., Liang, Z., & Yao, R. (2021). Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19). International journal of general medicine, 144711-4721. https://doi.org/10.2147/IJGM.S326204
Huang, Dong, et al. "Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19)." International journal of general medicine vol. 14 (2021): 4711-4721. doi: https://doi.org/10.2147/IJGM.S326204
Huang D, Yang H, Yu H, Wang T, Chen Z, Liang Z, Yao R. Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19). Int J Gen Med. 2021 Aug 21;14:4711-4721. doi: 10.2147/IJGM.S326204. eCollection 2021. PMID: 34456583; PMCID: PMC8387643.
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Design of Multifunctional Agent Based on Basified Serum Albumin for Efficient .

ACS applied bio materials

Wang W, Liu W, Xu S, Dong X, Sun Y.
PMID: 35025379
ACS Appl Bio Mater. 2020 May 18;3(5):3365-3377. doi: 10.1021/acsabm.0c00295. Epub 2020 May 05.

Theranostics, the combination of therapeutics and diagnostics, has emerged as a sophisticated, integrated, and advanced tool in the prevention and treatment of serious diseases, such as Alzheimer's disease (AD). However, the preclinical research of an AD theranostic molecule is...

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Wang W, Liu W, Xu S, et al. Design of Multifunctional Agent Based on Basified Serum Albumin for Efficient . ACS Appl Bio Mater. 2020;3(5):3365-3377doi: 10.1021/acsabm.0c00295.
Wang, W., Liu, W., Xu, S., Dong, X., & Sun, Y. (2020). Design of Multifunctional Agent Based on Basified Serum Albumin for Efficient . ACS applied bio materials, 3(5), 3365-3377. https://doi.org/10.1021/acsabm.0c00295
Wang, Wenjuan, et al. "Design of Multifunctional Agent Based on Basified Serum Albumin for Efficient ." ACS applied bio materials vol. 3,5 (2020): 3365-3377. doi: https://doi.org/10.1021/acsabm.0c00295
Wang W, Liu W, Xu S, Dong X, Sun Y. Design of Multifunctional Agent Based on Basified Serum Albumin for Efficient . ACS Appl Bio Mater. 2020 May 18;3(5):3365-3377. doi: 10.1021/acsabm.0c00295. Epub 2020 May 05. PMID: 35025379.
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Showing 5665 to 5675 of 5675 entries