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Showing 217 to 221 of 221 entries
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mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation.

Skeletal muscle

Roy N, Sundar S, Pillai M, Patell-Socha F, Ganesh S, Aloysius A, Rumman M, Gala H, Hughes SM, Zammit PS, Dhawan J.
PMID: 34238354
Skelet Muscle. 2021 Jul 08;11(1):18. doi: 10.1186/s13395-021-00270-9.

BACKGROUND: During skeletal muscle regeneration, satellite stem cells use distinct pathways to repair damaged myofibers or to self-renew by returning to quiescence. Cellular/mitotic quiescence employs mechanisms that promote a poised or primed state, including altered RNA turnover and translational...

ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index.

Skeletal muscle

Hinkle ER, Essader TO, Gentile GM, Giudice J.
PMID: 34915930
Skelet Muscle. 2021 Dec 16;11(1):28. doi: 10.1186/s13395-021-00284-3.

BACKGROUND: Measuring biological features of skeletal muscle cells is difficult because of their unique morphology and multinucleate nature upon differentiation. Here, we developed a new Fiji macro package called ViaFuse (that stands for viability and fusion) to measure skeletal...

ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index.

Skeletal muscle

Hinkle ER, Essader TO, Gentile GM, Giudice J.
PMID: 34915930
Skelet Muscle. 2021 Dec 16;11(1):28. doi: 10.1186/s13395-021-00284-3.

BACKGROUND: Measuring biological features of skeletal muscle cells is difficult because of their unique morphology and multinucleate nature upon differentiation. Here, we developed a new Fiji macro package called ViaFuse (that stands for viability and fusion) to measure skeletal...

Muscle atrophy induced by overexpression of ALAS2 is related to muscle mitochondrial dysfunction.

Skeletal muscle

Peng Y, Li J, Luo D, Zhang S, Li S, Wang D, Wang X, Zhang Z, Wang X, Sun C, Gao X, Hui Y, He R.
PMID: 33785075
Skelet Muscle. 2021 Mar 30;11(1):9. doi: 10.1186/s13395-021-00263-8.

BACKGROUND: ALAS2 (delta-aminolevulinate synthase 2) is one of the two isoenzymes catalyzing the synthesis of delta-aminolevulinic acid (ALA), which is the first precursor of heme synthesis. ALAS2-overexpressing transgenic mice (Tg mice) showed syndrome of porphyria, a series of diseases...

Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study.

Skeletal muscle

Dhaliwal A, Williams FR, Quinlan JI, Allen SL, Greig C, Filer A, Raza K, Ghosh S, Lavery GG, Newsome PN, Choudhary S, Breen L, Armstrong MJ, Elsharkawy AM, Lord JM.
PMID: 34895316
Skelet Muscle. 2021 Dec 11;11(1):27. doi: 10.1186/s13395-021-00282-5.

BACKGROUND: Several chronic inflammatory diseases co-exist with and accelerate sarcopenia (reduction in muscle strength, function and mass) and negatively impact on both morbidity and mortality. There is currently limited research on the extent of sarcopenia in such conditions, how...

Showing 217 to 221 of 221 entries