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Showing 13 to 24 of 26 entries
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Poly[[diaqua-μ(6)-succinato-di-μ(5)-succinato-didysprosium(III)] mono-hydrate].

Acta crystallographica. Section E, Structure reports online

Xu W, Chang HS, Guo XX.
PMID: 21836969
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 01;67:m998. doi: 10.1107/S1600536811024330. Epub 2011 Jun 30.

The title compound, {[Dy(2)(C(4)H(4)O(4))(3)(H(2)O)(2)]·H(2)O}(n), is isostructural with other lanthanide succinates of the same formula. The Dy(III) atom is nine-coordinated in a tricapped trigonal-prismatic environment by eight O atoms, derived from six carboxyl-ate groups and a water mol-ecule. One of...

Structural implications of lipoarabinomannan glycans from global clinical isolates in diagnosis of Mycobacterium tuberculosis infection.

The Journal of biological chemistry

De P, Amin AG, Flores D, Simpson A, Dobos K, Chatterjee D.
PMID: 34600887
J Biol Chem. 2021 Nov;297(5):101265. doi: 10.1016/j.jbc.2021.101265. Epub 2021 Sep 30.

In Mycobacterium tuberculosis (Mtb), surface-exposed Lipoarabinomannan (LAM) is a key determinant of immunogenicity, yet its intrinsic heterogeneity confounds typical structure-function analysis. Recently, LAM gained a strong foothold as a validated marker for active tuberculosis (TB) infection and has shown...

Succinate esters: odd-even effects in melting points.

Acta crystallographica Section B, Structural science, crystal engineering and materials

Joseph S, Sathishkumar R.
PMID: 25274517
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2014 Oct;70:839-46. doi: 10.1107/S2052520614013730. Epub 2014 Sep 18.

Dialkyl succinates show a pattern of alternating behavior in their melting points, as the number of C atoms in the alkane side chain increases, unlike in the dialkyl oxalates [Joseph et al. (2011). Acta Cryst. B67, 525-534]. Dialkyl succinates...

Dynamic kinetic resolution of 2-oxo-3-aryl-succinates by organocatalyzed aldolization.

Chemical communications (Cambridge, England)

Wang Y, Shen Z, Li B, Zhang Y, Zhang Y.
PMID: 17356784
Chem Commun (Camb). 2007 Mar 28;(12):1284-6. doi: 10.1039/b616382c. Epub 2007 Jan 12.

The dynamic kinetic resolution of 2-oxo-3-arylsuccinates was achieved vial-proline-catalyzed addition of acetone in acetonitrile at room temperature, providing the desired adduct in good yield with up to 87 : 13 dr and high ee up to 99%.

Versatile transformations of hydrocarbons in anaerobic bacteria: substrate ranges and regio- and stereo-chemistry of activation reactions.

Frontiers in microbiology

Jarling R, Kühner S, Basílio Janke E, Gruner A, Drozdowska M, Golding BT, Rabus R, Wilkes H.
PMID: 26441848
Front Microbiol. 2015 Sep 07;6:880. doi: 10.3389/fmicb.2015.00880. eCollection 2015.

Anaerobic metabolism of hydrocarbons proceeds either via addition to fumarate or by hydroxylation in various microorganisms, e.g., sulfate-reducing or denitrifying bacteria, which are specialized in utilizing n-alkanes or alkylbenzenes as growth substrates. General pathways for carbon assimilation and energy...

Polymer Distribution and Mechanism Conversion in Multiple Media of Phase-Separated Controlled-Release Film-Coating.

Pharmaceutics

Chen L, Yang G, Chu X, Gao C, Wang Y, Gong W, Li Z, Yang Y, Yang M, Gao C.
PMID: 30769846
Pharmaceutics. 2019 Feb 14;11(2). doi: 10.3390/pharmaceutics11020080.

Phase-separated films of water-insoluble ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be utilized to tailor drug release from coated pellets. In the present study, the effects of HPC levels and the pH, type, ionic strength and osmolarity...

Diaminoterephthalates: scaffolds for combinatorial chemistry.

Chemistry (Weinheim an der Bergstrasse, Germany)

Pflantz R, Christoffers J.
PMID: 19142933
Chemistry. 2009;15(9):2200-9. doi: 10.1002/chem.200802151.

Fluorescent building blocks: Tetracarboxyamides with a central fluorescent diaminoterephthalate unit were prepared from succinyl succinates following a combinatorial-like strategy. The 2,5-diaminoterephthalates (see scheme; PG=protecting group) possess four points of diversification and are introduced as new scaffolds for combinatorial chemistry.2,5-Diaminoterephthalates...

Supramolecular architectures of succinates of 1-hydroxypropan-2-aminium derivatives.

Acta crystallographica. Section C, Structural chemistry

Żesławska E, Nitek W, Marona H, Waszkielewicz AM.
PMID: 29973425
Acta Crystallogr C Struct Chem. 2018 Jul 01;74:856-862. doi: 10.1107/S2053229618008574. Epub 2018 Jun 19.

Aminoalkanol and aroxyalkyl derivatives are known as potential anticonvulsants. Two new salts, namely bis{(R,S)-N-[2-(2,6-dimethylphenoxy)ethyl]-1-hydroxypropan-2-aminium} succinate (1s), C

Multifunctional self-delivery micelles targeting the invasion-metastasis cascade for enhanced chemotherapy against melanoma and the lung metastasis.

Asian journal of pharmaceutical sciences

Xu S, Liu C, Zang S, Li J, Wang Y, Ren K, Li M, Zhang Z, He Q.
PMID: 35027954
Asian J Pharm Sci. 2021 Nov;16(6):794-805. doi: 10.1016/j.ajps.2021.08.002. Epub 2021 Sep 16.

Metastasis is closely related to the high mortality of cancer patients, which is regulated by multiple signaling pathways. Hence, multiphase blocking of this biological process is beneficial for cancer treatments. Herein, we establish a multifunctional self-delivering system by synthesizing...

Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates.

Biotechnology and bioengineering

Wang Y, Nguyen N, Lee SH, Wang Q, May JA, Gonzalez R, Cirino PC.
PMID: 34633065
Biotechnol Bioeng. 2022 Jan;119(1):315-320. doi: 10.1002/bit.27956. Epub 2021 Oct 16.

In anoxic environments, microbial activation of alkanes for subsequent metabolism occurs most commonly through the addition of fumarate to a subterminal carbon, producing an alkylsuccinate. Alkylsuccinate synthases are complex, multi-subunit enzymes that utilize a catalytic glycyl radical and require...

Asymmetric hydrogenation of maleic acid diesters and anhydrides.

Angewandte Chemie (International ed. in English)

Bernasconi M, Müller MA, Pfaltz A.
PMID: 24711207
Angew Chem Int Ed Engl. 2014 May 19;53(21):5385-8. doi: 10.1002/anie.201402034. Epub 2014 Apr 07.

Asymmetric hydrogenation of maleic and fumaric acid derivatives with iridium catalysts based on N,P ligands provides an efficient route to chiral enantioenriched succinates. A new catalyst derived from a 2,6-difluorophenyl-substituted pyridine-phosphinite ligand was developed and enables the conversion of...

Multifunctional self-delivery micelles targeting the invasion-metastasis cascade for enhanced chemotherapy against melanoma and the lung metastasis.

Asian journal of pharmaceutical sciences

Xu S, Liu C, Zang S, Li J, Wang Y, Ren K, Li M, Zhang Z, He Q.
PMID: 35027954
Asian J Pharm Sci. 2021 Nov;16(6):794-805. doi: 10.1016/j.ajps.2021.08.002. Epub 2021 Sep 16.

Metastasis is closely related to the high mortality of cancer patients, which is regulated by multiple signaling pathways. Hence, multiphase blocking of this biological process is beneficial for cancer treatments. Herein, we establish a multifunctional self-delivering system by synthesizing...

Showing 13 to 24 of 26 entries