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Showing 25 to 36 of 102 entries
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An Investigation into Variability in the Therapeutic Response to Deferiprone in Patients with Thalassemia Major: Retraction.

Therapeutic drug monitoring

[No authors listed]
PMID: 30768496
Ther Drug Monit. 2019 Apr;41(2):256. doi: 10.1097/FTD.0000000000000607.

No abstract available.

The relation between dosage, serum concentrations, and clinical outcome in children and adolescents treated with sertraline: a naturalistic study: Erratum.

Therapeutic drug monitoring

[No authors listed]
PMID: 29746436
Ther Drug Monit. 2018 Jun;40(3):381. doi: 10.1097/FTD.0000000000000527.

No abstract available.

Population pharmacokinetics of sirolimus in pediatric patients with neurofibromatosis type 1-Erratum.

Therapeutic drug monitoring

Scott JR, Courter JD, Saldaña SN, Widemann BC, Fisher M, Weiss B, Perentesis J, Vinks AA.
PMID: 26829601
Ther Drug Monit. 2016 Apr;38(2):284. doi: 10.1097/FTD.0000000000000275. Epub 2016 Jan 21.

No abstract available.

Erratum.

Therapeutic drug monitoring

[No authors listed]
PMID: 33297287
Ther Drug Monit. 2014 Feb;36(1):124. doi: 10.1097/FTD.0000000000000040.

No abstract available.

Decreased Systemic Busulfan Exposure After Oral Dosing With Concomitant Levetiracetam Compared To Phenytoin.

Therapeutic drug monitoring

Artul T, Henig I, Nassar L, Yehudai-Ofir D, Scherb MDI, Lurie Y, Efrati E, Zuckerman T, Kurnik D.
PMID: 34739424
Ther Drug Monit. 2021 Oct 26; doi: 10.1097/FTD.0000000000000938. Epub 2021 Oct 26.

BACKGROUND: Busulfan (Bu) conditioning used in hematopoietic stem cell transplantation (HSCT) may induce seizures, and prophylactic antiepileptic treatment is recommended. Following updated guidelines, in August 2019, the adult HSCT department of the Rambam Health Care Campus (Haifa, Israel) switched...

Evaluation of Omeprazole Limited Sampling Strategies to Estimate Constitutive Cytochrome P450 2C19 Activity in Healthy Adults: Erratum.

Therapeutic drug monitoring

[No authors listed]
PMID: 30883523
Ther Drug Monit. 2019 Apr;41(2):256. doi: 10.1097/FTD.0000000000000624.

No abstract available.

Development of a novel analytical method for determining trazodone in human plasma by LC-MS coupled with automatic 2-dimensional liquid chromatograph-mass spectrometer coupler 9500 and its application to therapeutic drug monitoring.

Therapeutic drug monitoring

Ding J, Zhang Y, Cui X, Zhao C, Zhang S.
PMID: 34469419
Ther Drug Monit. 2021 Aug 27; doi: 10.1097/FTD.0000000000000921. Epub 2021 Aug 27.

BACKGROUND: Trazodone (TZD) is a tetracyclic serotonin antagonist and reuptake inhibitor that is used as a second-generation phenylpiperazine antidepressant. However, the plasma concentrations of TZD have shown individual variations in clinical practice. Quantification of TZD plasma concentrations may be...

Drug-drug interactions with OTC medicines: mind the unprescribed.

Therapeutic drug monitoring

Oliver SC.
PMID: 34469416
Ther Drug Monit. 2021 Aug 27; doi: 10.1097/FTD.0000000000000924. Epub 2021 Aug 27.

PURPOSE: This review provides a summary of the currently available clinical data on drug-drug interactions (DDIs) involving over-the-counter (OTC) medicines. It aims to educate and increase awareness among healthcare providers, and to support decisions in daily practice.METHODS: An extensive...

Health Care Costs of Target Attainment for Beta-Lactam Antibiotics in Critically Ill Patients: A Retrospective Analysis of the EXPAT Study.

Therapeutic drug monitoring

Ewoldt TMJ, Abdulla A, Hunfeld NGM, Muller AE, Gommers D, Polinder S, Koch BCP, Endeman H.
PMID: 33770020
Ther Drug Monit. 2022 Feb 01;44(1):224-229. doi: 10.1097/FTD.0000000000000891.

BACKGROUND: Optimizing beta-lactam antibiotic treatment is a promising method to reduce the length of intensive care unit (ICU) stay and therefore reduce ICU costs. We used data from the EXPAT trial to determine whether beta-lactam antibiotic target attainment is...

Interindividual Variability in the Bioavailability of Gabapentin Enacarbil Extended Release in Healthy Adults: An Analysis of Data From Six Phase I Studies.

Therapeutic drug monitoring

Lal R, Ellenbogen A, Gidal B.
PMID: 34726199
Ther Drug Monit. 2021 Nov 01; doi: 10.1097/FTD.0000000000000935. Epub 2021 Nov 01.

BACKGROUND: The absorption and bioavailability of oral gabapentin are associated with a high degree of interindividual variability. Gabapentin enacarbil, a prodrug of gabapentin, is well absorbed and provides sustained, dose-proportional exposure to gabapentin. The aim of this analysis was...

Therapeutic Drug Monitoring of Antibiotic Drugs: The Role of the Clinical Laboratory.

Therapeutic drug monitoring

Shipkova M, Jamoussi H.
PMID: 34726200
Ther Drug Monit. 2021 Nov 01; doi: 10.1097/FTD.0000000000000934. Epub 2021 Nov 01.

PURPOSE: Therapeutic drug monitoring (TDM) of anti-infective drugs is an increasingly complex field, given that in addition to the patient and drug as two usual determinants, its success is driven by the pathogen. Pharmacodynamics is related both to the...

Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites.

Therapeutic drug monitoring

Fay EE, Czuba LC, Sager JE, Shum S, Stephenson-Famy A, Isoherranen N.
PMID: 33814540
Ther Drug Monit. 2021 Dec 01;43(6):780-788. doi: 10.1097/FTD.0000000000000885.

BACKGROUND: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP (OH-BUP) as well as by 11β-hydroxysteroid...

Showing 25 to 36 of 102 entries