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Showing 169 to 178 of 178 entries
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Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma.

American journal of ophthalmology case reports

Mishra KK, Scholey JE, Daftari IK, Afshar A, Tsai T, Park S, Quivey JM, Char DH.
PMID: 32760850
Am J Ophthalmol Case Rep. 2020 Jun 22;19:100787. doi: 10.1016/j.ajoc.2020.100787. eCollection 2020 Sep.

PURPOSE: To describe the first series of six young uveal melanoma (UM) patients with oral isotretinoin and/or topical retinoid therapy prior to diagnosis.OBSERVATIONS: The case series is based on clinical observations at our UM quaternary referral center. Six UM...

Phase I Trial of Lithium and Tretinoin for Treatment of Relapsed and Refractory Non-promyelocytic Acute Myeloid Leukemia.

Frontiers in oncology

Ueda M, Stefan T, Stetson L, Ignatz-Hoover JJ, Tomlinson B, Creger RJ, Cooper B, Lazarus HM, de Lima M, Wald DN, Caimi PF.
PMID: 32211336
Front Oncol. 2020 Mar 10;10:327. doi: 10.3389/fonc.2020.00327. eCollection 2020.

Glycogen synthase kinase-3 (GSK3) inhibitors induce differentiation and growth inhibition of acute myeloid leukemia (AML) cells. Our pre-clinical studies showed GSK3 inhibition leads to sensitization of AML cells to tretinoin-mediated differentiation. We conducted a phase I trial of lithium,...

A Fiber Alginate Co-culture Platform for the Differentiation of mESC and Modeling of the Neural Tube.

Frontiers in neuroscience

Fannon OM, Bithell A, Whalley BJ, Delivopoulos E.
PMID: 33510605
Front Neurosci. 2021 Jan 12;14:524346. doi: 10.3389/fnins.2020.524346. eCollection 2020.

Alginate hydrogels are a commonly used substrate for

Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis.

Scientific reports

Farber M, Chen Y, Arnold L, Möllmann M, Boog-Whiteside E, Lin YA, Reinhardt HC, Dührsen U, Hanoun M.
PMID: 34764342
Sci Rep. 2021 Nov 11;11(1):22062. doi: 10.1038/s41598-021-01300-8.

Targeting the interaction between leukemic cells and the microenvironment is an appealing approach to enhance the therapeutic efficacy in acute myeloid leukemia (AML). AML infiltration induces a significant release of inflammatory cytokines in the human bone marrow niche which...

Evidence for the Efficacy of Over-the-counter Vitamin A Cosmetic Products in the Improvement of Facial Skin Aging: A Systematic Review.

The Journal of clinical and aesthetic dermatology

Spierings NMK.
PMID: 34980969
J Clin Aesthet Dermatol. 2021 Sep;14(9):33-40.

BACKGROUND: Skincare retailers sell a plethora of retinol-containing products, ranging from serums and moisturisers to masks and eye creams.OBJECTIVE: The purpose of this review is to critically appraise the randomized, double-blind, vehicle-controlled trials of the use of over-the-counter retinol...

Enhanced Synergistic-Antioxidant Activity of Melatonin and Tretinoin by Co-encapsulation into Amphiphilic Chitosan Nanocarriers: During Mice In Vitro Matured Oocyte/Morula-Compact Stage Embryo Culture Model.

Reproductive sciences (Thousand Oaks, Calif.)

Aghaz F, Vaisi-Raygani A, Khazaei M, Arkan E, Kashanian S.
PMID: 34231166
Reprod Sci. 2021 Dec;28(12):3361-3379. doi: 10.1007/s43032-021-00670-8. Epub 2021 Jul 06.

The use of exogenous antioxidants or the combination of them during in vitro oocyte/embryo culture media is reasonable. Co-delivery by nanocarrier has been designed to overcome the limitations of combining them traditionally. In this work, amphiphilic chitosan nanocarrier (ACN)...

Youthful and age-related matreotypes predict drugs promoting longevity.

Aging cell

Statzer C, Jongsma E, Liu SX, Dakhovnik A, Wandrey F, Mozharovskyi P, Zülli F, Ewald CY.
PMID: 34346557
Aging Cell. 2021 Sep;20(9):e13441. doi: 10.1111/acel.13441. Epub 2021 Aug 04.

The identification and validation of drugs that promote health during aging ("geroprotectors") are key to the retardation or prevention of chronic age-related diseases. Here, we found that most of the established pro-longevity compounds shown to extend lifespan in model...

Evidence for the Efficacy of Over-the-counter Vitamin A Cosmetic Products in the Improvement of Facial Skin Aging: A Systematic Review.

The Journal of clinical and aesthetic dermatology

Spierings NMK.
PMID: 34980969
J Clin Aesthet Dermatol. 2021 Sep;14(9):33-40.

BACKGROUND: Skincare retailers sell a plethora of retinol-containing products, ranging from serums and moisturisers to masks and eye creams.OBJECTIVE: The purpose of this review is to critically appraise the randomized, double-blind, vehicle-controlled trials of the use of over-the-counter retinol...

Formulation and Evaluation of a Topical Niosomal Gel Containing a Combination of Benzoyl Peroxide and Tretinoin for Antiacne Activity [Retraction].

International journal of nanomedicine

[No authors listed]
PMID: 34168452
Int J Nanomedicine. 2021 Jun 18;16:4195. doi: 10.2147/IJN.S320896. eCollection 2021.

[This retracts the article DOI: 10.2147/IJN.S70449.].

The efficacy and safety of topical Tretinoin combined with superficial X-ray therapy (SXRT) in treating periungual warts.

Dermatologic therapy

Xu J, Zhang D, Feng L, Liu Y, Diao Q.
PMID: 34967065
Dermatol Ther. 2021 Dec 29;e15295. doi: 10.1111/dth.15295. Epub 2021 Dec 29.

There are multiple treatment modalities for periungual warts (PWs), although most are destructive and painful, limiting their application. Radiotherapy is a non-invasive method suitable for treating PW patients with contraindications to invasive procedures. To investigate the efficacy and safety...

Showing 169 to 178 of 178 entries