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Interview: An interview with Chad Mirkin: nanomedicine expert. Interviewed by Hannah Stanwix.

Nanomedicine (London, England)

Mirkin C.
PMID: 22630148
Nanomedicine (Lond). 2012 May;7(5):635-8. doi: 10.2217/nnm.12.44.

Chad Mirkin speaks to Hannah Stanwix, Assistant Commissioning Editor Professor Chad Mirkin received his Bachelor of Science Degree in Chemistry from Dickinson College (PA, USA) in 1986. He holds a PhD in Chemistry from Pennsylvania State University (PA, USA)...

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Mirkin C. Interview: An interview with Chad Mirkin: nanomedicine expert. Interviewed by Hannah Stanwix. Nanomedicine (Lond). 2012;7(5):635-8doi: 10.2217/nnm.12.44.
Mirkin, C. (2012). Interview: An interview with Chad Mirkin: nanomedicine expert. Interviewed by Hannah Stanwix. Nanomedicine (London, England), 7(5), 635-8. https://doi.org/10.2217/nnm.12.44
Mirkin, Chad. "Interview: An interview with Chad Mirkin: nanomedicine expert. Interviewed by Hannah Stanwix." Nanomedicine (London, England) vol. 7,5 (2012): 635-8. doi: https://doi.org/10.2217/nnm.12.44
Mirkin C. Interview: An interview with Chad Mirkin: nanomedicine expert. Interviewed by Hannah Stanwix. Nanomedicine (Lond). 2012 May;7(5):635-8. doi: 10.2217/nnm.12.44. PMID: 22630148; PMCID: PMC4629713.
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A Multimodal Nanocomposite for Biomedical Imaging.

AIP conference proceedings

Wu A, Paunesku T, Zhang Z, Vogt S, Lai B, Maser J, Yaghmai V, Li D, Omary RA, Woloschak GE.
PMID: 24817775
AIP Conf Proc. 2011 Sep 09;1365:379. doi: 10.1063/1.3625382.

A multimodal nanocomposite was designed, synthesized with super-paramagnetic core (CoFe

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Wu A, Paunesku T, Zhang Z, et al. A Multimodal Nanocomposite for Biomedical Imaging. AIP Conf Proc. 2011;1365:379doi: 10.1063/1.3625382.
Wu, A., Paunesku, T., Zhang, Z., Vogt, S., Lai, B., Maser, J., Yaghmai, V., Li, D., Omary, R. A., & Woloschak, G. E. (2011). A Multimodal Nanocomposite for Biomedical Imaging. AIP conference proceedings, 1365379. https://doi.org/10.1063/1.3625382
Wu, Aiguo, et al. "A Multimodal Nanocomposite for Biomedical Imaging." AIP conference proceedings vol. 1365 (2011): 379. doi: https://doi.org/10.1063/1.3625382
Wu A, Paunesku T, Zhang Z, Vogt S, Lai B, Maser J, Yaghmai V, Li D, Omary RA, Woloschak GE. A Multimodal Nanocomposite for Biomedical Imaging. AIP Conf Proc. 2011 Sep 09;1365:379. doi: 10.1063/1.3625382. PMID: 24817775; PMCID: PMC4012782.
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Bimodal Imaging Using Neodymium Doped Gadolinium Fluoride Nanocrystals with Near-Infrared to Near-Infrared Downconversion Luminescence and Magnetic Resonance Properties.

Journal of materials chemistry. B

Mimun LC, Ajithkumar G, Pokhrel M, Yust BG, Elliott ZG, Pedraza F, Dhanale A, Tang L, Lin AL, Dravid VP, Sardar DK.
PMID: 25584192
J Mater Chem B. 2013 Nov 07;1(41):5702-5710. doi: 10.1039/C3TB20905A.

Here we report the synthesis, characterization and application of a multifunctional surface functionalized GdF

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Mimun LC, Ajithkumar G, Pokhrel M, et al. Bimodal Imaging Using Neodymium Doped Gadolinium Fluoride Nanocrystals with Near-Infrared to Near-Infrared Downconversion Luminescence and Magnetic Resonance Properties. J Mater Chem B. 2013;1(41):5702-5710doi: 10.1039/C3TB20905A.
Mimun, L. C., Ajithkumar, G., Pokhrel, M., Yust, B. G., Elliott, Z. G., Pedraza, F., Dhanale, A., Tang, L., Lin, A. L., Dravid, V. P., & Sardar, D. K. (2013). Bimodal Imaging Using Neodymium Doped Gadolinium Fluoride Nanocrystals with Near-Infrared to Near-Infrared Downconversion Luminescence and Magnetic Resonance Properties. Journal of materials chemistry. B, 1(41), 5702-5710. https://doi.org/10.1039/C3TB20905A
Mimun, L Christopher, et al. "Bimodal Imaging Using Neodymium Doped Gadolinium Fluoride Nanocrystals with Near-Infrared to Near-Infrared Downconversion Luminescence and Magnetic Resonance Properties." Journal of materials chemistry. B vol. 1,41 (2013): 5702-5710. doi: https://doi.org/10.1039/C3TB20905A
Mimun LC, Ajithkumar G, Pokhrel M, Yust BG, Elliott ZG, Pedraza F, Dhanale A, Tang L, Lin AL, Dravid VP, Sardar DK. Bimodal Imaging Using Neodymium Doped Gadolinium Fluoride Nanocrystals with Near-Infrared to Near-Infrared Downconversion Luminescence and Magnetic Resonance Properties. J Mater Chem B. 2013 Nov 07;1(41):5702-5710. doi: 10.1039/C3TB20905A. PMID: 25584192; PMCID: PMC4288854.
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Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples.

Cancers

Chen S, Lastra RO, Paunesku T, Antipova O, Li L, Deng J, Luo Y, Wanzer MB, Popovic J, Li Y, Glasco AD, Jacobsen C, Vogt S, Woloschak GE.
PMID: 34503306
Cancers (Basel). 2021 Sep 06;13(17). doi: 10.3390/cancers13174497.

Research in cancer nanotechnology is entering its third decade, and the need to study interactions between nanomaterials and cells remains urgent. Heterogeneity of nanoparticle uptake by different cells and subcellular compartments represent the greatest obstacles to a full understanding...

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Chen S, Lastra RO, Paunesku T, et al. Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples. Cancers (Basel). 2021;13(17)doi: 10.3390/cancers13174497.
Chen, S., Lastra, R. O., Paunesku, T., Antipova, O., Li, L., Deng, J., Luo, Y., Wanzer, M. B., Popovic, J., Li, Y., Glasco, A. D., Jacobsen, C., Vogt, S., & Woloschak, G. E. (2021). Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples. Cancers, 13(17), . https://doi.org/10.3390/cancers13174497
Chen, Si, et al. "Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples." Cancers vol. 13,17 (2021). doi: https://doi.org/10.3390/cancers13174497
Chen S, Lastra RO, Paunesku T, Antipova O, Li L, Deng J, Luo Y, Wanzer MB, Popovic J, Li Y, Glasco AD, Jacobsen C, Vogt S, Woloschak GE. Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples. Cancers (Basel). 2021 Sep 06;13(17). doi: 10.3390/cancers13174497. PMID: 34503306; PMCID: PMC8430782.
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Light-induced self-assembly of nanofibers inside liposomes.

Soft matter

Lee HK, Soukasene S, Jiang H, Zhang S, Feng W, Stupp SI.
PMID: 19412333
Soft Matter. 2008 May 01;4(5):962-964. doi: 10.1039/b719486b.

Spatially confined self-assembly of peptide amphiphile nanofibers inside liposomes is triggered by light.

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Lee HK, Soukasene S, Jiang H, et al. Light-induced self-assembly of nanofibers inside liposomes. Soft Matter. 2008;4(5):962-964doi: 10.1039/b719486b.
Lee, H. K., Soukasene, S., Jiang, H., Zhang, S., Feng, W., & Stupp, S. I. (2008). Light-induced self-assembly of nanofibers inside liposomes. Soft matter, 4(5), 962-964. https://doi.org/10.1039/b719486b
Lee, Hyung-Kun, et al. "Light-induced self-assembly of nanofibers inside liposomes." Soft matter vol. 4,5 (2008): 962-964. doi: https://doi.org/10.1039/b719486b
Lee HK, Soukasene S, Jiang H, Zhang S, Feng W, Stupp SI. Light-induced self-assembly of nanofibers inside liposomes. Soft Matter. 2008 May 01;4(5):962-964. doi: 10.1039/b719486b. PMID: 19412333; PMCID: PMC2662686.
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The Polyvalent Gold Nanoparticle Conjugate-Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation.

MRS bulletin

Mirkin CA.
PMID: 34539060
MRS Bull. 2010 Jul;35(7):532-539. doi: 10.1557/mrs2010.602. Epub 2011 Jan 31.

Advances in nanoscale directed assembly strategies have enabled researchers to analogize atomic assembly via chemical reactions and nanoparticle assembly, creating a new nanoscale "periodic table." We are just beginning to realize the nanoparticle equivalents of molecules and extended materials...

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Mirkin CA. The Polyvalent Gold Nanoparticle Conjugate-Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation. MRS Bull. 2011;35(7):532-539doi: 10.1557/mrs2010.602.
Mirkin, C. A. (2010). The Polyvalent Gold Nanoparticle Conjugate-Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation. MRS bulletin, 35(7), 532-539. https://doi.org/10.1557/mrs2010.602
Mirkin, Chad A. "The Polyvalent Gold Nanoparticle Conjugate-Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation." MRS bulletin vol. 35,7 (2010): 532-539. doi: https://doi.org/10.1557/mrs2010.602
Mirkin CA. The Polyvalent Gold Nanoparticle Conjugate-Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation. MRS Bull. 2010 Jul;35(7):532-539. doi: 10.1557/mrs2010.602. Epub 2011 Jan 31. PMID: 34539060; PMCID: PMC8445035.
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Synthesis and .

Journal of materials chemistry

Smith D, Clark SH, Bertin PA, Mirkin BL, Nguyen ST.
PMID: 24421587
J Mater Chem. 2009 Apr 21;19(15):2159-2165. doi: 10.1039/B817511J.

A new type of polymer nanoparticle (PNP) containing a high density of covalently linked doxorubicin, attached via a non-cleavable amine linkage (amine-linked Dox-PNP) was prepared. Together with a previously reported cleavable carbamate-linked Dox-PNP, this new amine-linked Dox-PNP was subsequently...

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Smith D, Clark SH, Bertin PA, et al. Synthesis and . J Mater Chem. 2009;19(15):2159-2165doi: 10.1039/B817511J.
Smith, D., Clark, S. H., Bertin, P. A., Mirkin, B. L., & Nguyen, S. T. (2009). Synthesis and . Journal of materials chemistry, 19(15), 2159-2165. https://doi.org/10.1039/B817511J
Smith, Deedee, et al. "Synthesis and ." Journal of materials chemistry vol. 19,15 (2009): 2159-2165. doi: https://doi.org/10.1039/B817511J
Smith D, Clark SH, Bertin PA, Mirkin BL, Nguyen ST. Synthesis and . J Mater Chem. 2009 Apr 21;19(15):2159-2165. doi: 10.1039/B817511J. PMID: 24421587; PMCID: PMC3888582.
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Enhanced optical transmission mediated by localized plasmons in anisotropic, three-dimensional nanohole arrays.

Nano letters

Yang JC, Gao H, Suh JY, Zhou W, Lee MH, Odom TW.
PMID: 20698633
Nano Lett. 2010 Aug 11;10(8):3173-8. doi: 10.1021/nl102078j.

This paper describes three-dimensional (3D) nanohole arrays whose high optical transmission is mediated more by localized surface plasmon (LSP) excitations than by surface plasmon polaritons (SPPs). First, LSPs on 3D hole arrays lead to optical transmission an order of...

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Yang JC, Gao H, Suh JY, et al. Enhanced optical transmission mediated by localized plasmons in anisotropic, three-dimensional nanohole arrays. Nano Lett. 2010;10(8):3173-8doi: 10.1021/nl102078j.
Yang, J. C., Gao, H., Suh, J. Y., Zhou, W., Lee, M. H., & Odom, T. W. (2010). Enhanced optical transmission mediated by localized plasmons in anisotropic, three-dimensional nanohole arrays. Nano letters, 10(8), 3173-8. https://doi.org/10.1021/nl102078j
Yang, Jiun-Chan, et al. "Enhanced optical transmission mediated by localized plasmons in anisotropic, three-dimensional nanohole arrays." Nano letters vol. 10,8 (2010): 3173-8. doi: https://doi.org/10.1021/nl102078j
Yang JC, Gao H, Suh JY, Zhou W, Lee MH, Odom TW. Enhanced optical transmission mediated by localized plasmons in anisotropic, three-dimensional nanohole arrays. Nano Lett. 2010 Aug 11;10(8):3173-8. doi: 10.1021/nl102078j. PMID: 20698633; PMCID: PMC2921222.
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A Three-Channel Spectrometer for Wide-Field Imaging of Anisotropic Plasmonic Nanoparticles.

The journal of physical chemistry. C, Nanomaterials and interfaces

Sweeney CM, Nehl CL, Hasan W, Liang T, Eckermann A, Meade TJ, Odom TW.
PMID: 21927639
J Phys Chem C Nanomater Interfaces. 2011 Aug 18;115(32):15933-15937. doi: 10.1021/jp206157v.

A three-channel spectrometer (3CS) based on a commercial digital camera was developed to distinguish among tens of large (>100 nm), anisotropic plasmonic particles with various shapes, orientations, and compositions on a surface simultaneously. Using band pass filters and polarizers,...

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Sweeney CM, Nehl CL, Hasan W, et al. A Three-Channel Spectrometer for Wide-Field Imaging of Anisotropic Plasmonic Nanoparticles. J Phys Chem C Nanomater Interfaces. 2011;115(32):15933-15937doi: 10.1021/jp206157v.
Sweeney, C. M., Nehl, C. L., Hasan, W., Liang, T., Eckermann, A., Meade, T. J., & Odom, T. W. (2011). A Three-Channel Spectrometer for Wide-Field Imaging of Anisotropic Plasmonic Nanoparticles. The journal of physical chemistry. C, Nanomaterials and interfaces, 115(32), 15933-15937. https://doi.org/10.1021/jp206157v
Sweeney, Christina M, et al. "A Three-Channel Spectrometer for Wide-Field Imaging of Anisotropic Plasmonic Nanoparticles." The journal of physical chemistry. C, Nanomaterials and interfaces vol. 115,32 (2011): 15933-15937. doi: https://doi.org/10.1021/jp206157v
Sweeney CM, Nehl CL, Hasan W, Liang T, Eckermann A, Meade TJ, Odom TW. A Three-Channel Spectrometer for Wide-Field Imaging of Anisotropic Plasmonic Nanoparticles. J Phys Chem C Nanomater Interfaces. 2011 Aug 18;115(32):15933-15937. doi: 10.1021/jp206157v. PMID: 21927639; PMCID: PMC3171732.
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Multimodal bioimaging using rare earth doped Gd.

Journal of materials chemistry. A

Ajithkumar G, Yoo B, Goral DE, Hornsby PJ, Lin AL, Ladiwala U, Dravid VP, Sardar DK.
PMID: 25191618
J Mater Chem A Mater. 2013 Mar 21;1(11):1561-1572. doi: 10.1039/C3TB00551H.

While infrared upconversion imaging using halide nanoparticles are so common the search for a very efficient halide free upconverting phosphors is still lacking. In this article we report Gd

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Ajithkumar G, Yoo B, Goral DE, et al. Multimodal bioimaging using rare earth doped Gd. J Mater Chem A Mater. 2013;1(11):1561-1572doi: 10.1039/C3TB00551H.
Ajithkumar, G., Yoo, B., Goral, D. E., Hornsby, P. J., Lin, A. L., Ladiwala, U., Dravid, V. P., & Sardar, D. K. (2013). Multimodal bioimaging using rare earth doped Gd. Journal of materials chemistry. A, 1(11), 1561-1572. https://doi.org/10.1039/C3TB00551H
Ajithkumar, G, et al. "Multimodal bioimaging using rare earth doped Gd." Journal of materials chemistry. A vol. 1,11 (2013): 1561-1572. doi: https://doi.org/10.1039/C3TB00551H
Ajithkumar G, Yoo B, Goral DE, Hornsby PJ, Lin AL, Ladiwala U, Dravid VP, Sardar DK. Multimodal bioimaging using rare earth doped Gd. J Mater Chem A Mater. 2013 Mar 21;1(11):1561-1572. doi: 10.1039/C3TB00551H. PMID: 25191618; PMCID: PMC4151623.
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Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging.

The journal of physical chemistry. C, Nanomaterials and interfaces

Hu F, MacRenaris KW, Waters EA, Liang T, Schultz-Sikma EA, Eckermann AL, Meade TJ.
PMID: 24991303
J Phys Chem C Nanomater Interfaces. 2009 Dec 10;113(49):20855-20860. doi: 10.1021/jp907216g.

Ultrasmall (3, 4, 5, and 6 nm), water-soluble Fe

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Hu F, MacRenaris KW, Waters EA, et al. Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging. J Phys Chem C Nanomater Interfaces. 2009;113(49):20855-20860doi: 10.1021/jp907216g.
Hu, F., MacRenaris, K. W., Waters, E. A., Liang, T., Schultz-Sikma, E. A., Eckermann, A. L., & Meade, T. J. (2009). Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging. The journal of physical chemistry. C, Nanomaterials and interfaces, 113(49), 20855-20860. https://doi.org/10.1021/jp907216g
Hu, Fengqin, et al. "Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging." The journal of physical chemistry. C, Nanomaterials and interfaces vol. 113,49 (2009): 20855-20860. doi: https://doi.org/10.1021/jp907216g
Hu F, MacRenaris KW, Waters EA, Liang T, Schultz-Sikma EA, Eckermann AL, Meade TJ. Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging. J Phys Chem C Nanomater Interfaces. 2009 Dec 10;113(49):20855-20860. doi: 10.1021/jp907216g. PMID: 24991303; PMCID: PMC4076104.
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Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine.

Tetrahedron letters

Liu Z, Hu BH, Messersmith PB.
PMID: 20543896
Tetrahedron Lett. 2010 May 01;51(18):2403-2405. doi: 10.1016/j.tetlet.2010.02.089.

Direct acetonide protection of the catechol of dopamine has proven to be problematic due to formation of Pictet-Spengler isoquinolines. Here we report an efficient method for acetonide protection of dopamine, allowing preparation of a dopamine prodrug without complications from...

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Liu Z, Hu BH, Messersmith PB. Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine. Tetrahedron Lett. 2010;51(18):2403-2405doi: 10.1016/j.tetlet.2010.02.089.
Liu, Z., Hu, B. H., & Messersmith, P. B. (2010). Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine. Tetrahedron letters, 51(18), 2403-2405. https://doi.org/10.1016/j.tetlet.2010.02.089
Liu, Zhongqiang, et al. "Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine." Tetrahedron letters vol. 51,18 (2010): 2403-2405. doi: https://doi.org/10.1016/j.tetlet.2010.02.089
Liu Z, Hu BH, Messersmith PB. Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine. Tetrahedron Lett. 2010 May 01;51(18):2403-2405. doi: 10.1016/j.tetlet.2010.02.089. PMID: 20543896; PMCID: PMC2882309.
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