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Showing 517 to 524 of 524 entries
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Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis.

Hepatology communications

Ghadieh HE, Abu Helal R, Muturi HT, Issa DD, Russo L, Abdallah SL, Najjar JA, Benencia F, Vazquez G, Li W, Najjar SM.
PMID: 33163831
Hepatol Commun. 2020 Sep 03;4(11):1591-1609. doi: 10.1002/hep4.1590. eCollection 2020 Nov.

Patients with nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) commonly develop atherosclerosis through a mechanism that is not well delineated. These diseases are associated with steatosis, inflammation, oxidative stress, and fibrosis. The role of insulin resistance in their pathogenesis remains controversial....

Association between adverse childhood experiences among children with special healthcare needs and dental care utilization.

Journal of public health dentistry

Wiener RC, Bhandari R.
PMID: 33751582
J Public Health Dent. 2021 Mar 09; doi: 10.1111/jphd.12450. Epub 2021 Mar 09.

OBJECTIVES: Adverse childhood experiences (ACEs) often have consequences beyond the immediacy of any specific event. The purpose of this study is to identify if ACEs in children with special healthcare needs (CSHCN) are associated with oral problems and dental...

Primary obesity surgery endoluminal (POSE) for the treatment of obesity: a systematic review and meta-analysis.

Surgical endoscopy

Singh S, Bazarbashi AN, Khan A, Chowdhry M, Bilal M, de Moura DTH, Jirapinyo P, Thakkar S, Thompson CC.
PMID: 33523277
Surg Endosc. 2022 Jan;36(1):252-266. doi: 10.1007/s00464-020-08267-z. Epub 2021 Feb 01.

BACKGROUND: Primary obesity surgery endoluminal (POSE) utilizes an incision-less operating platform system to create full-thickness plications in the gastric fundus and body (original POSE). Many studies have demonstrated the safety and efficacy of original POSE for the treatment of...

Human Papillomavirus Vaccine Messaging on TikTok: Social Media Content Analysis.

Health promotion practice

Boatman DD, Eason S, Conn ME, Kennedy-Rea SK.
PMID: 33969725
Health Promot Pract. 2021 May 10;15248399211013002. doi: 10.1177/15248399211013002. Epub 2021 May 10.

BACKGROUND: The human papillomavirus (HPV) vaccine is viewed as a critical tool to protect against six HPV-related cancers. Vaccination is recommended from early adolescence through age 26 years. As young people have become increasingly involved in personal health-related decisions,...

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.

Cancer discovery

Chung J, Maruvka YE, Sudhaman S, Kelly J, Haradhvala NJ, Bianchi V, Edwards M, Forster VJ, Nunes NM, Galati MA, Komosa M, Deshmukh S, Cabric V, Davidson S, Zatzman M, Light N, Hayes R, Brunga L, Anderson ND, Ho B, Hodel KP, Siddaway R, Morrissy AS, Bowers DC, Larouche V, Bronsema A, Osborn M, Cole KA, Opocher E, Mason G, Thomas GA, George B, Ziegler DS, Lindhorst S, Vanan M, Yalon-Oren M, Reddy AT, Massimino M, Tomboc P, Van Damme A, Lossos A, Durno C, Aronson M, Morgenstern DA, Bouffet E, Huang A, Taylor MD, Villani A, Malkin D, Hawkins CE, Pursell ZF, Shlien A, Kunkel TA, Getz G, Tabori U.
PMID: 33355208
Cancer Discov. 2021 May;11(5):1176-1191. doi: 10.1158/2159-8290.CD-20-0790. Epub 2020 Dec 18.

Although replication repair deficiency, either by mismatch repair deficiency (MMRD) and/or loss of DNA polymerase proofreading, can cause hypermutation in cancer, microsatellite instability (MSI) is considered a hallmark of MMRD alone. By genome-wide analysis of tumors with germline and...

Tissue-level cytokines in a rodent model of chronic implant-associated infection.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Prince N, Penatzer JA, Shackleford TL, Stewart EK, Dietz MJ, Boyd JW.
PMID: 33283316
J Orthop Res. 2021 Oct;39(10):2159-2168. doi: 10.1002/jor.24940. Epub 2020 Dec 15.

Systemic cytokine concentrations have been extensively studied in implant-associated infections, providing sensitive diagnostic markers. However, less is known about the relationships of tissue-level cytokines surrounding the joint. The aim of this study was to define the cytokine profiles of...

Chronic stress induced perivascular adipose tissue impairment of aortic function and the therapeutic effect of exercise.

Experimental physiology

DeVallance ER, Branyan KW, Olfert IM, Pistilli EE, Bryner RW, Kelley EE, Frisbee JC, Chantler PD.
PMID: 33913209
Exp Physiol. 2021 Jun;106(6):1343-1358. doi: 10.1113/EP089449. Epub 2021 May 14.

NEW FINDINGS: What is the central question of this study? Thoracic perivascular adipose tissue (tPVAT) is known to, in part, regulate aortic function: what are the effects of unpredictable chronic mild stress (UCMS) on the tPVAT regulation of aortic...

Baseline Plasma Inflammatory Profile Is Associated With Response to Neoadjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma.

Journal of immunotherapy (Hagerstown, Md. : 1997)

Chopra A, Zamora R, Vodovotz Y, Hodges JC, Barclay D, Brand R, Simmons RL, Lee KK, Paniccia A, Murthy P, Lotze MT, Boone BA, Zureikat AH.
PMID: 33935273
J Immunother. 2021 Jun 01;44(5):185-192. doi: 10.1097/CJI.0000000000000370.

Despite its increased application in pancreatic ductal adenocarcinoma (PDAC), complete response to neoadjuvant therapy (NAT) is rare. Given the critical role of host immunity in regulating cancer, we sought to correlate baseline inflammatory profiles to significant response to NAT....

Showing 517 to 524 of 524 entries