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Showing 13 to 15 of 15 entries
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Erratum: Author Correction: Mendelian neurodegenerative disease genes involved in autophagy.

Cell discovery

Stamatakou E, Wrobel L, Hill SM, Puri C, Son SM, Fujimaki M, Zhu Y, Siddiqi F, Fernandez-Estevez M, Manni MM, Park SJ, Villeneuve J, Rubinsztein DC.
PMID: 32566248
Cell Discov. 2020 Jun 16;6:40. doi: 10.1038/s41421-020-0185-8. eCollection 2020.

[This corrects the article DOI: 10.1038/s41421-020-0158-y.].

Breakthroughs and bottlenecks in autophagy research.

Trends in molecular medicine

Mizushima N, White E, Rubinsztein DC.
PMID: 34257008
Trends Mol Med. 2021 Sep;27(9):835-838. doi: 10.1016/j.molmed.2021.06.012. Epub 2021 Jul 11.

The study of autophagy has grown exponentially over the past two decades, and significant progress has been made in our understanding of its mechanisms and physiological significance. However, its application to human diseases remains limited. Here, we summarize the...

Transient siRNA-mediated protein knockdown in mouse followed by feeding/starving cycle and liver tissue analysis.

STAR protocols

Wrobel L, Siddiqi FH, Rubinsztein DC.
PMID: 33997814
STAR Protoc. 2021 Apr 27;2(2):100500. doi: 10.1016/j.xpro.2021.100500. eCollection 2021 Jun 18.

We present a protocol for in vivo siRNA-mediated knockdown of a gene of interest in mouse liver using systemic delivery via intravenous injection. We describe a step-by-step protocol for delivery of siRNA particles, with tips on how to optimize...

Showing 13 to 15 of 15 entries