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Showing 25 to 36 of 159 entries
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Estrogen Receptor-β Expression of Ovarian Tumors and Its Association with Ovarian Cancer Risk Factors.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Shafrir AL, Babic A, Gates Kuliszewski M, Rice MS, Townsend MK, Hecht JL, Tworoger SS.
PMID: 32856599
Cancer Epidemiol Biomarkers Prev. 2020 Nov;29(11):2211-2219. doi: 10.1158/1055-9965.EPI-20-0618. Epub 2020 Aug 20.

BACKGROUND: Differential associations between ovarian cancer risk factors and estrogen receptor-α (ERα) ovarian tumor expression have been noted; however, no research has assessed estrogen receptor-β (ERβ) expression. Thus, in exploratory analyses, we assessed the association of several factors with...

Associations of Oral Contraceptives with Mammographic Breast Density in Premenopausal Women.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Yaghjyan L, Smotherman C, Heine J, Colditz GA, Rosner B, Tamimi RM.
PMID: 34862209
Cancer Epidemiol Biomarkers Prev. 2021 Dec 03; doi: 10.1158/1055-9965.EPI-21-0853. Epub 2021 Dec 03.

BACKGROUND: We investigated the associations of oral contraceptives (OC) with percent breast density (PD), absolute dense area (DA), nondense area (NDA), and a novel image intensity variation (V) measure in premenopausal women.METHODS: This study included 1,233 controls from a...

Genome-Wide Gene-Diabetes and Gene-Obesity Interaction Scan in 8,255 Cases and 11,900 Controls from PanScan and PanC4 Consortia.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Tang H, Jiang L, Stolzenberg-Solomon RZ, Arslan AA, Beane Freeman LE, Bracci PM, Brennan P, Canzian F, Du M, Gallinger S, Giles GG, Goodman PJ, Kooperberg C, Le Marchand L, Neale RE, Shu XO, Visvanathan K, White E, Zheng W, Albanes D, Andreotti G, Babic A, Bamlet WR, Berndt SI, Blackford A, Bueno-de-Mesquita B, Buring JE, Campa D, Chanock SJ, Childs E, Duell EJ, Fuchs C, Gaziano JM, Goggins M, Hartge P, Hassam MH, Holly EA, Hoover RN, Hung RJ, Kurtz RC, Lee IM, Malats N, Milne RL, Ng K, Oberg AL, Orlow I, Peters U, Porta M, Rabe KG, Rothman N, Scelo G, Sesso HD, Silverman DT, Thompson IM, Tjønneland A, Trichopoulou A, Wactawski-Wende J, Wentzensen N, Wilkens LR, Yu H, Zeleniuch-Jacquotte A, Amundadottir LT, Jacobs EJ, Petersen GM, Wolpin BM, Risch HA, Chatterjee N, Klein AP, Li D, Kraft P, Wei P.
PMID: 32546605
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1784-1791. doi: 10.1158/1055-9965.EPI-20-0275. Epub 2020 Jun 16.

BACKGROUND: Obesity and diabetes are major modifiable risk factors for pancreatic cancer. Interactions between genetic variants and diabetes/obesity have not previously been comprehensively investigated in pancreatic cancer at the genome-wide level.METHODS: We conducted a gene-environment interaction (GxE) analysis including...

Discovery and Features of an Alkylating Signature in Colorectal Cancer.

Cancer discovery

Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, Fuchs CS, Wu K, Ogino S, Giannakis M.
PMID: 34140290
Cancer Discov. 2021 Oct;11(10):2446-2455. doi: 10.1158/2159-8290.CD-20-1656. Epub 2021 Jun 17.

Several risk factors have been established for colorectal cancer, yet their direct mutagenic effects in patients' tumors remain to be elucidated. Here, we leveraged whole-exome sequencing data from 900 colorectal cancer cases that had occurred in three U.S.-wide prospective...

Intake of fruits and vegetables according to pesticide residue status in relation to all-cause and disease-specific mortality: Results from three prospective cohort studies.

Environment international

Sandoval-Insausti H, Chiu YH, Wang YX, Hart JE, Bhupathiraju SN, Mínguez-Alarcón L, Ding M, Willett WC, Laden F, Chavarro JE.
PMID: 34894487
Environ Int. 2022 Jan 15;159:107024. doi: 10.1016/j.envint.2021.107024. Epub 2021 Dec 08.

BACKGROUND: Intake of conventionally grown fruits and vegetables (FVs) is an important route of exposure to pesticide residues in the general population. However, whether health risk stemming from exposure to pesticides through diet could offset benefits of consuming FVs...

Healthful and Unhealthful Plant-Based Diets and Risk of Breast Cancer in U.S. Women: Results from the Nurses' Health Studies.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Romanos-Nanclares A, Willett WC, Rosner BA, Collins LC, Hu FB, Toledo E, Eliassen AH.
PMID: 34289970
Cancer Epidemiol Biomarkers Prev. 2021 Oct;30(10):1921-1931. doi: 10.1158/1055-9965.EPI-21-0352. Epub 2021 Jul 21.

BACKGROUND: Plant-based diets have been associated with lower risk of various diseases, including type 2 diabetes, cardiovascular disease, and other cardiometabolic risk factors. However, the association between plant-based diet quality and breast cancer remains unclear.METHODS: We prospectively followed 76,690...

Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Yadav S, Hu C, Nathanson KL, Weitzel JN, Goldgar DE, Kraft P, Gnanaolivu RD, Na J, Huang H, Boddicker NJ, Larson N, Gao C, Yao S, Weinberg C, Vachon CM, Trentham-Dietz A, Taylor JA, Sandler DR, Patel A, Palmer JR, Olson JE, Neuhausen S, Martinez E, Lindstrom S, Lacey JV, Kurian AW, John EM, Haiman C, Bernstein L, Auer PW, Anton-Culver H, Ambrosone CB, Karam R, Chao E, Yussuf A, Pesaran T, Dolinsky JS, Hart SN, LaDuca H, Polley EC, Domchek SM, Couch FJ.
PMID: 34672684
J Clin Oncol. 2021 Dec 10;39(35):3918-3926. doi: 10.1200/JCO.21.00640. Epub 2021 Oct 21.

PURPOSE: To determine the contribution of germline pathogenic variants (PVs) in hereditary cancer testing panel genes to invasive lobular carcinoma (ILC) of the breast.MATERIALS AND METHODS: The study included 2,999 women with ILC from a population-based cohort and 3,796...

Prediagnostic Inflammation and Pancreatic Cancer Survival.

Journal of the National Cancer Institute

Yuan C, Morales-Oyarvide V, Khalaf N, Perez K, Tabung FK, Ho GYF, Kooperberg C, Shadyab AH, Qi L, Kraft P, Sesso HD, Giovannucci EL, Manson JE, Stampfer MJ, Ng K, Fuchs CS, Wolpin BM, Babic A.
PMID: 33739411
J Natl Cancer Inst. 2021 Sep 04;113(9):1186-1193. doi: 10.1093/jnci/djab040.

BACKGROUND: Chronic inflammation may promote initiation and progression of pancreatic cancer, but no studies have examined the association between inflammation in the period before diagnosis and pancreatic cancer survival.METHODS: We prospectively examined the association of prediagnostic plasma levels of...

Sleep Duration and Snoring at Midlife in Relation to Healthy Aging in Women 70 Years of Age or Older.

Nature and science of sleep

Shi H, Huang T, Ma Y, Eliassen AH, Sun Q, Wang M.
PMID: 33762862
Nat Sci Sleep. 2021 Mar 17;13:411-422. doi: 10.2147/NSS.S302452. eCollection 2021.

PURPOSE: Both short and long sleep durations are associated with higher mortality. This study examined the association between sleep duration and overall health among those who survive to older ages.PARTICIPANTS AND METHODS: In the Nurses' Health Study, participants without...

Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location.

Clinical and translational gastroenterology

Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, Kostic AD, Giannakis M, Bullman S, Brennan CA, Milner DA, Baba H, Garraway LA, Meyerhardt JA, Garrett WS, Huttenhower C, Meyerson M, Giovannucci EL, Fuchs CS, Nishihara R, Ogino S.
PMID: 27811909
Clin Transl Gastroenterol. 2016 Nov 03;7(11):e200. doi: 10.1038/ctg.2016.53.

OBJECTIVES: Evidence suggests a possible role of Fusobacterium nucleatum in colorectal carcinogenesis, especially in right-sided proximal colorectum. Considering a change in bowel contents and microbiome from proximal to distal colorectal segments, we hypothesized that the proportion of colorectal carcinoma...

Associations of reproductive breast cancer risk factors with breast tissue composition.

Breast cancer research : BCR

Yaghjyan L, Austin-Datta RJ, Oh H, Heng YJ, Vellal AD, Sirinukunwattana K, Baker GM, Collins LC, Murthy D, Rosner B, Tamimi RM.
PMID: 34225771
Breast Cancer Res. 2021 Jul 05;23(1):70. doi: 10.1186/s13058-021-01447-2.

BACKGROUND: We investigated the associations of reproductive factors with the percentage of epithelium, stroma, and fat tissue in benign breast biopsy samples.METHODS: This study included 983 cancer-free women with biopsy-confirmed benign breast disease (BBD) within the Nurses' Health Study...

Gluten Intake and Risk of Digestive System Cancers in 3 Large Prospective Cohort Studies.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Wang Y, Cao Y, Lebwohl B, Song M, Sun Q, Green PHR, Giovannucci EL, Willett WC, Chan AT.
PMID: 34800737
Clin Gastroenterol Hepatol. 2021 Nov 17; doi: 10.1016/j.cgh.2021.11.016. Epub 2021 Nov 17.

BACKGROUND & AIMS: In patients with celiac disease, gluten triggers an immune reaction that damages small intestinal villi and may increase long-term risk of gastrointestinal cancer. However, the health impacts of gluten in the general population are understudied. We...

Showing 25 to 36 of 159 entries