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Showing 25 to 34 of 34 entries
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Correction: TLR7 trafficking and signaling in B cells is regulated by the MHCII-associated invariant chain.

Journal of cell science

Tohme M, Maisonneuve L, Achour K, Dussiot M, Maschalidi S, Manoury B.
PMID: 34713886
J Cell Sci. 2021 Oct 15;134(20). doi: 10.1242/jcs.259376. Epub 2021 Oct 29.

No abstract available.

Molecular and cellular analyses of HLA class II-associated susceptibility to autoimmune diseases in the Japanese population.

Modern rheumatology

Nishimura Y, Ito H, Fujii S, Tabata H, Tokano Y, Chen YZ, Matsuda I, Mitsuya H, Kira J, Hashimoto H, Senju S, Matsushita S.
PMID: 24383685
Mod Rheumatol. 2001 Jun;11(2):103-12. doi: 10.3109/s101650170020.

Abstract It is well known that individuals who are positive for particular HLA class II alleles show a high risk of developing autoimmune diseases. HLA class II molecules expressed on antigen-presenting cells present antigenic peptides to CD4(+) T cells....

Invariant chain--a regulator of antigen presentation.

Trends in cell biology

Teyton L, Peterson PA.
PMID: 14731527
Trends Cell Biol. 1992 Feb;2(2):52-6. doi: 10.1016/0962-8924(92)90163-h.

MHC class II molecules present internalized antigens to the immune system. They have long been known to associate with a polypeptide called the invariant chain. Recent findings have revealed that this polypeptide performs two functions. First, it prevents class...

Levetiracetam Differentially Alters CD95 Expression of Neuronal Cells and the Mitochondrial Membrane Potential of Immune and Neuronal Cells in vitro.

Frontiers in neurology

Rogers SK, Shapiro LA, Tobin RP, Tow B, Zuzek A, Mukherjee S, Newell-Rogers MK.
PMID: 24600432
Front Neurol. 2014 Feb 18;5:17. doi: 10.3389/fneur.2014.00017. eCollection 2014.

Epilepsy is a neurological seizure disorder that affects over 100 million people worldwide. Levetiracetam, either alone, as monotherapy, or as adjunctive treatment, is widely used to control certain types of seizures. Despite its increasing popularity as a relatively safe...

Dataset of clinical, immunohistopathological and laboratory features of patients with MHC II deficiency suffering from enteropathy.

Data in brief

Posovszky C, Sirin M, Jacobsen E, Lorenz M, Schwarz K, Schmidt-Choudhury A, Schütz C, Hönig M, Debatin KM, Schulz A, Möller P, Barth TF.
PMID: 31516959
Data Brief. 2019 Aug 28;26:104446. doi: 10.1016/j.dib.2019.104446. eCollection 2019 Oct.

Major histocompatibility complex class II (MHC II) is essential for adaptive immune response. We recently reported on disturbed adaptive mucosal immunity due to MHC II deficiency and prolonged enteropathy. Here, we share medical history, flow cytometric analysis of blood...

Aberrant Expression of and Cell Death Induction by Engagement of the MHC-II Chaperone CD74 in Anaplastic Large Cell Lymphoma (ALCL).

Cancers

Wurster KD, Costanza M, Kreher S, Glaser S, Lamprecht B, Schleussner N, Anagnostopoulos I, Hummel M, Jöhrens K, Stein H, Molina A, Diepstra A, Gillissen B, Köchert K, Siebert R, Merkel O, Kenner L, Janz M, Mathas S.
PMID: 34638496
Cancers (Basel). 2021 Oct 07;13(19). doi: 10.3390/cancers13195012.

In 50-60% of cases, systemic anaplastic large cell lymphoma (ALCL) is characterized by the t(2;5)(p23;q35) or one of its variants, considered to be causative for anaplastic lymphoma kinase (ALK)-positive (ALK

HLA Class II Presentation Is Specifically Altered at Elevated Temperatures in the B-Lymphoblastic Cell Line JY.

Molecular & cellular proteomics : MCP

Demmers LC, Wu W, Heck AJR.
PMID: 33933681
Mol Cell Proteomics. 2021 Apr 29;20:100089. doi: 10.1016/j.mcpro.2021.100089. Epub 2021 Apr 29.

Human leukocyte antigen (HLA) molecules play critical roles in our adaptive immune system by signaling a cell's health status to the immune system, through presentation of small peptides. Understanding HLA biology is important because of its prominent role in...

HLA Class II Presentation Is Specifically Altered at Elevated Temperatures in the B-Lymphoblastic Cell Line JY.

Molecular & cellular proteomics : MCP

Demmers LC, Wu W, Heck AJR.
PMID: 33933681
Mol Cell Proteomics. 2021;20:100089. doi: 10.1016/j.mcpro.2021.100089. Epub 2021 Apr 29.

Human leukocyte antigen (HLA) molecules play critical roles in our adaptive immune system by signaling a cell's health status to the immune system, through presentation of small peptides. Understanding HLA biology is important because of its prominent role in...

The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers.

BMC immunology

Cloutier M, Fortin JS, Thibodeau J.
PMID: 34384367
BMC Immunol. 2021 Aug 12;22(1):56. doi: 10.1186/s12865-021-00444-6.

BACKGROUND: Invariant chain (CD74, Ii) is a multifunctional protein expressed in antigen presenting cells. It assists the ER exit of various cargos and serves as a receptor for the macrophage migration inhibitory factor. The newly translated Ii chains trimerize,...

HLA Class II Presentation Is Specifically Altered at Elevated Temperatures in the B-Lymphoblastic Cell Line JY.

Molecular & cellular proteomics : MCP

Demmers LC, Wu W, Heck AJR.
PMID: 33933681
Mol Cell Proteomics. 2021;20:100089. doi: 10.1016/j.mcpro.2021.100089. Epub 2021 Apr 29.

Human leukocyte antigen (HLA) molecules play critical roles in our adaptive immune system by signaling a cell's health status to the immune system, through presentation of small peptides. Understanding HLA biology is important because of its prominent role in...

Showing 25 to 34 of 34 entries