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Immunomodulatory effects of .

Journal of parasitic diseases : official organ of the Indian Society for Parasitology

El Shanawany EE, Fouad EA, Keshta HG, Hassan SE, Hegazi AG, Abdel-Rahman EH.
PMID: 31749528
J Parasit Dis. 2019 Dec;43(4):583-591. doi: 10.1007/s12639-019-01130-6. Epub 2019 Aug 02.

The current study was designed to evaluate the in vivo fasciolicidal activity of

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El Shanawany EE, Fouad EA, Keshta HG, et al. Immunomodulatory effects of . J Parasit Dis. 2019;43(4):583-591doi: 10.1007/s12639-019-01130-6.
El Shanawany, E. E., Fouad, E. A., Keshta, H. G., Hassan, S. E., Hegazi, A. G., & Abdel-Rahman, E. H. (2019). Immunomodulatory effects of . Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 43(4), 583-591. https://doi.org/10.1007/s12639-019-01130-6
El Shanawany, Eman E, et al. "Immunomodulatory effects of ." Journal of parasitic diseases : official organ of the Indian Society for Parasitology vol. 43,4 (2019): 583-591. doi: https://doi.org/10.1007/s12639-019-01130-6
El Shanawany EE, Fouad EA, Keshta HG, Hassan SE, Hegazi AG, Abdel-Rahman EH. Immunomodulatory effects of . J Parasit Dis. 2019 Dec;43(4):583-591. doi: 10.1007/s12639-019-01130-6. Epub 2019 Aug 02. PMID: 31749528; PMCID: PMC6841766.
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Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma.

Clinics and research in hepatology and gastroenterology

Al-Khaykanee AM, Abdel-Rahman AA, Essa A, Gadallah AA, Ali BH, Al-Aqar AA, Badr EAE, Shehab-Eldeen S.
PMID: 33740609
Clin Res Hepatol Gastroenterol. 2021 Nov;45(6):101636. doi: 10.1016/j.clinre.2021.101636. Epub 2021 Mar 16.

BACKGROUND: Fibroblast growth factor receptor 2 (FGFR2) and trinucleotide repeat-containing 9 (TRNC9) gene polymorphisms have been associated with some cancers. We aimed to assess the association of FGFR2 rs2981582 and TRNC9 rs12443621 polymorphisms with hepatocellular cancer risk.METHODS: One hundred...

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Al-Khaykanee AM, Abdel-Rahman AA, Essa A, et al. Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma. Clin Res Hepatol Gastroenterol. 2021;45(6):101636doi: 10.1016/j.clinre.2021.101636.
Al-Khaykanee, A. M., Abdel-Rahman, A. A., Essa, A., Gadallah, A. A., Ali, B. H., Al-Aqar, A. A., Badr, E. A. E., & Shehab-Eldeen, S. (2021). Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma. Clinics and research in hepatology and gastroenterology, 45(6), 101636. https://doi.org/10.1016/j.clinre.2021.101636
Al-Khaykanee, Ahmed Mudher, et al. "Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma." Clinics and research in hepatology and gastroenterology vol. 45,6 (2021): 101636. doi: https://doi.org/10.1016/j.clinre.2021.101636
Al-Khaykanee AM, Abdel-Rahman AA, Essa A, Gadallah AA, Ali BH, Al-Aqar AA, Badr EAE, Shehab-Eldeen S. Genetic polymorphism of fibroblast growth factor receptor 2 and trinucleotide repeat-containing 9 influence the susceptibility to HCV-induced hepatocellular carcinoma. Clin Res Hepatol Gastroenterol. 2021 Nov;45(6):101636. doi: 10.1016/j.clinre.2021.101636. Epub 2021 Mar 16. PMID: 33740609.
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Fragmented landscapes affect honey bee colony strength at diverse spatial scales in agroecological landscapes in Kenya.

Ecological applications : a publication of the Ecological Society of America

Ochungo P, Veldtman R, Abdel-Rahman EM, Muli E, Ng'ang'a J, Tonnang HEZ, Landmann T.
PMID: 34674336
Ecol Appl. 2022 Jan;32(1):e02483. doi: 10.1002/eap.2483. Epub 2021 Nov 20.

Landscape fragmentation and habitat loss at multiple scales directly affect species abundance, diversity, and productivity. There is a paucity of information about the effect of the landscape structure and diversity on honey bee colony strength in Africa. Here, we...

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Ochungo P, Veldtman R, Abdel-Rahman EM, et al. Fragmented landscapes affect honey bee colony strength at diverse spatial scales in agroecological landscapes in Kenya. Ecol Appl. 2021;32(1):e02483doi: 10.1002/eap.2483.
Ochungo, P., Veldtman, R., Abdel-Rahman, E. M., Muli, E., Ng'ang'a, J., Tonnang, H. E. Z., & Landmann, T. (2022). Fragmented landscapes affect honey bee colony strength at diverse spatial scales in agroecological landscapes in Kenya. Ecological applications : a publication of the Ecological Society of America, 32(1), e02483. https://doi.org/10.1002/eap.2483
Ochungo, Pamela, et al. "Fragmented landscapes affect honey bee colony strength at diverse spatial scales in agroecological landscapes in Kenya." Ecological applications : a publication of the Ecological Society of America vol. 32,1 (2022): e02483. doi: https://doi.org/10.1002/eap.2483
Ochungo P, Veldtman R, Abdel-Rahman EM, Muli E, Ng'ang'a J, Tonnang HEZ, Landmann T. Fragmented landscapes affect honey bee colony strength at diverse spatial scales in agroecological landscapes in Kenya. Ecol Appl. 2022 Jan;32(1):e02483. doi: 10.1002/eap.2483. Epub 2021 Nov 20. PMID: 34674336.
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Acute gastric volvulus: A rare case report and literature review.

Annals of medicine and surgery (2012)

Albloushi D, Quttaineh D, Alsafran S, Alyatama K, Alfawaz AA, Alsulaimy M, Saber S, Abdel-Rahman AS.
PMID: 34691417
Ann Med Surg (Lond). 2021 Sep 13;70:102857. doi: 10.1016/j.amsu.2021.102857. eCollection 2021 Oct.

INTRODUCTION AND IMPORTANCE: Gastric volvulus is the abnormal gastric rotation upon itself. It carries a considerable risk for gastric strangulation which may lead to gangrene and perforation, which can be fatal. It commonly presents with non-specific and vague abdominal...

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Albloushi D, Quttaineh D, Alsafran S, et al. Acute gastric volvulus: A rare case report and literature review. Ann Med Surg (Lond). 2021;70:102857doi: 10.1016/j.amsu.2021.102857.
Albloushi, D., Quttaineh, D., Alsafran, S., Alyatama, K., Alfawaz, A. A., Alsulaimy, M., Saber, S., & Abdel-Rahman, A. S. (2021). Acute gastric volvulus: A rare case report and literature review. Annals of medicine and surgery (2012), 70102857. https://doi.org/10.1016/j.amsu.2021.102857
Albloushi, Dalia, et al. "Acute gastric volvulus: A rare case report and literature review." Annals of medicine and surgery (2012) vol. 70 (2021): 102857. doi: https://doi.org/10.1016/j.amsu.2021.102857
Albloushi D, Quttaineh D, Alsafran S, Alyatama K, Alfawaz AA, Alsulaimy M, Saber S, Abdel-Rahman AS. Acute gastric volvulus: A rare case report and literature review. Ann Med Surg (Lond). 2021 Sep 13;70:102857. doi: 10.1016/j.amsu.2021.102857. eCollection 2021 Oct. PMID: 34691417; PMCID: PMC8519751.
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Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats.

Heliyon

El-Gendy ZA, El-Marasy SA, Ahmed RF, El-Batran SA, Abd El-Rahman SS, Ramadan A, Youssef SAH.
PMID: 34159266
Heliyon. 2021 May 27;7(6):e07159. doi: 10.1016/j.heliyon.2021.e07159. eCollection 2021 Jun.

Fibrosis represents a common outcome of almost all chronic liver diseases and leads to an impairment of liver function that requires medical intervention. The current study aimed to evaluate the potential anti-fibrotic effect of

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El-Gendy ZA, El-Marasy SA, Ahmed RF, et al. Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats. Heliyon. 2021;7(6):e07159doi: 10.1016/j.heliyon.2021.e07159.
El-Gendy, Z. A., El-Marasy, S. A., Ahmed, R. F., El-Batran, S. A., Abd El-Rahman, S. S., Ramadan, A., & Youssef, S. A. H. (2021). Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats. Heliyon, 7(6), e07159. https://doi.org/10.1016/j.heliyon.2021.e07159
El-Gendy, Zeinab A, et al. "Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats." Heliyon vol. 7,6 (2021): e07159. doi: https://doi.org/10.1016/j.heliyon.2021.e07159
El-Gendy ZA, El-Marasy SA, Ahmed RF, El-Batran SA, Abd El-Rahman SS, Ramadan A, Youssef SAH. Hepatoprotective effect of Saccharomyces Cervisciae Cell Wall Extract against thioacetamide-induced liver fibrosis in rats. Heliyon. 2021 May 27;7(6):e07159. doi: 10.1016/j.heliyon.2021.e07159. eCollection 2021 Jun. PMID: 34159266; PMCID: PMC8203708.
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Profiling Pretomanid as a Therapeutic Option for TB Infection: Evidence to Date.

Drug design, development and therapy

Stancil SL, Mirzayev F, Abdel-Rahman SM.
PMID: 34234413
Drug Des Devel Ther. 2021 Jun 28;15:2815-2830. doi: 10.2147/DDDT.S281639. eCollection 2021.

Tuberculosis (TB) is the most deadly infectious disease globally. Although most individuals achieve a cure, a substantial portion develop multi-drug resistant TB which is exceedingly difficult to treat, and the number of effective agents is dwindling. Development of new...

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Stancil SL, Mirzayev F, Abdel-Rahman SM. Profiling Pretomanid as a Therapeutic Option for TB Infection: Evidence to Date. Drug Des Devel Ther. 2021;15:2815-2830doi: 10.2147/DDDT.S281639.
Stancil, S. L., Mirzayev, F., & Abdel-Rahman, S. M. (2021). Profiling Pretomanid as a Therapeutic Option for TB Infection: Evidence to Date. Drug design, development and therapy, 152815-2830. https://doi.org/10.2147/DDDT.S281639
Stancil, Stephani L, et al. "Profiling Pretomanid as a Therapeutic Option for TB Infection: Evidence to Date." Drug design, development and therapy vol. 15 (2021): 2815-2830. doi: https://doi.org/10.2147/DDDT.S281639
Stancil SL, Mirzayev F, Abdel-Rahman SM. Profiling Pretomanid as a Therapeutic Option for TB Infection: Evidence to Date. Drug Des Devel Ther. 2021 Jun 28;15:2815-2830. doi: 10.2147/DDDT.S281639. eCollection 2021. PMID: 34234413; PMCID: PMC8253981.
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Role of thigh circumference in predicting the fetal weight: Comparison with other ultrasound methods-A prospective observational study.

The journal of obstetrics and gynaecology research

Mohamed MA, Ali AE, Mohamed MS, Abd El-Rahman MM.
PMID: 34601765
J Obstet Gynaecol Res. 2021 Dec;47(12):4210-4215. doi: 10.1111/jog.15032. Epub 2021 Oct 03.

AIM: We aimed to evaluate the addition of fetal thigh circumference (TC) to other ultrasound parameters to predict fetal weight compared to two standard formulae (Hadlock's and Vintzileos methods).METHODS: We conducted this prospective study on pregnant women between November...

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Mohamed MA, Ali AE, Mohamed MS, et al. Role of thigh circumference in predicting the fetal weight: Comparison with other ultrasound methods-A prospective observational study. J Obstet Gynaecol Res. 2021;47(12):4210-4215doi: 10.1111/jog.15032.
Mohamed, M. A., Ali, A. E., Mohamed, M. S., & Abd El-Rahman, M. M. (2021). Role of thigh circumference in predicting the fetal weight: Comparison with other ultrasound methods-A prospective observational study. The journal of obstetrics and gynaecology research, 47(12), 4210-4215. https://doi.org/10.1111/jog.15032
Mohamed, Menna-Allah, et al. "Role of thigh circumference in predicting the fetal weight: Comparison with other ultrasound methods-A prospective observational study." The journal of obstetrics and gynaecology research vol. 47,12 (2021): 4210-4215. doi: https://doi.org/10.1111/jog.15032
Mohamed MA, Ali AE, Mohamed MS, Abd El-Rahman MM. Role of thigh circumference in predicting the fetal weight: Comparison with other ultrasound methods-A prospective observational study. J Obstet Gynaecol Res. 2021 Dec;47(12):4210-4215. doi: 10.1111/jog.15032. Epub 2021 Oct 03. PMID: 34601765.
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Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus.

Frontiers in molecular biosciences

Gu X, Al Dubayee M, Alshahrani A, Masood A, Benabdelkamel H, Zahra M, Li L, Abdel Rahman AM, Aljada A.
PMID: 33381523
Front Mol Biosci. 2020 Dec 14;7:609806. doi: 10.3389/fmolb.2020.609806. eCollection 2020.

Obesity is associated with an increased risk of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) which is a multi-factorial disease associated with a dysregulated metabolism and can be prevented in pre-diabetic individuals with impaired glucose tolerance. A...

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Gu X, Al Dubayee M, Alshahrani A, et al. Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus. Front Mol Biosci. 2020;7:609806doi: 10.3389/fmolb.2020.609806.
Gu, X., Al Dubayee, M., Alshahrani, A., Masood, A., Benabdelkamel, H., Zahra, M., Li, L., Abdel Rahman, A. M., & Aljada, A. (2020). Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus. Frontiers in molecular biosciences, 7609806. https://doi.org/10.3389/fmolb.2020.609806
Gu, Xinyun, et al. "Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus." Frontiers in molecular biosciences vol. 7 (2020): 609806. doi: https://doi.org/10.3389/fmolb.2020.609806
Gu X, Al Dubayee M, Alshahrani A, Masood A, Benabdelkamel H, Zahra M, Li L, Abdel Rahman AM, Aljada A. Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus. Front Mol Biosci. 2020 Dec 14;7:609806. doi: 10.3389/fmolb.2020.609806. eCollection 2020. PMID: 33381523; PMCID: PMC7768025.
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2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes.

Oncotarget

El-Zein R, Thaiparambil J, Abdel-Rahman SZ.
PMID: 33400733
Oncotarget. 2020 Dec 01;11(48):4479-4489. doi: 10.18632/oncotarget.27810. eCollection 2020 Dec 01.

Centrosomes amplification is a hallmark of cancer. We hypothesize that 2-methoxyestradiol (2-ME) sensitizes breast cancer (BC) cells to taxanes by targeting amplified centrosomes. We assessed the extent by which 2-ME together with paclitaxel (PTX) induces centrosome alterations with subsequent...

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El-Zein R, Thaiparambil J, Abdel-Rahman SZ. 2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes. Oncotarget. 2020;11(48):4479-4489doi: 10.18632/oncotarget.27810.
El-Zein, R., Thaiparambil, J., & Abdel-Rahman, S. Z. (2020). 2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes. Oncotarget, 11(48), 4479-4489. https://doi.org/10.18632/oncotarget.27810
El-Zein, Randa, et al. "2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes." Oncotarget vol. 11,48 (2020): 4479-4489. doi: https://doi.org/10.18632/oncotarget.27810
El-Zein R, Thaiparambil J, Abdel-Rahman SZ. 2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes. Oncotarget. 2020 Dec 01;11(48):4479-4489. doi: 10.18632/oncotarget.27810. eCollection 2020 Dec 01. PMID: 33400733; PMCID: PMC7721614.
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Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway.

Molecules (Basel, Switzerland)

Alaaeldin R, Abdel-Rahman IAM, Hassan HA, Youssef N, Allam AE, Abdelwahab SF, Zhao QL, Fathy M.
PMID: 34946711
Molecules. 2021 Dec 16;26(24). doi: 10.3390/molecules26247629.

Insulin resistance contributes to several disorders including type 2 diabetes and cardiovascular diseases. Carpachromene is a natural active compound that inhibits α-glucosidase enzyme. The aim of the present study is to investigate the potential activity of carpachromene on glucose...

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Alaaeldin R, Abdel-Rahman IAM, Hassan HA, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021;26(24)doi: 10.3390/molecules26247629.
Alaaeldin, R., Abdel-Rahman, I. A. M., Hassan, H. A., Youssef, N., Allam, A. E., Abdelwahab, S. F., Zhao, Q. L., & Fathy, M. (2021). Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules (Basel, Switzerland), 26(24), . https://doi.org/10.3390/molecules26247629
Alaaeldin, Rania, et al. "Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway." Molecules (Basel, Switzerland) vol. 26,24 (2021). doi: https://doi.org/10.3390/molecules26247629
Alaaeldin R, Abdel-Rahman IAM, Hassan HA, Youssef N, Allam AE, Abdelwahab SF, Zhao QL, Fathy M. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26(24). doi: 10.3390/molecules26247629. PMID: 34946711; PMCID: PMC8708443.
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The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats.

PloS one

Abdel-Rahman RF, Fayed HM, Asaad GF, Ogaly HA, Hessin AF, Salama AAA, Abd El-Rahman SS, Arbid MS, Mohamed MAE.
PMID: 34965258
PLoS One. 2021 Dec 29;16(12):e0260130. doi: 10.1371/journal.pone.0260130. eCollection 2021.

The objective of the current study is to investigate the effect of rice bran oil (RBO) on hepatic fibrosis as a characteristic response to persistent liver injuries. Rats were randomly allocated into five groups: the negative control group, thioacetamide...

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Abdel-Rahman RF, Fayed HM, Asaad GF, et al. The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats. PLoS One. 2021;16(12):e0260130doi: 10.1371/journal.pone.0260130.
Abdel-Rahman, R. F., Fayed, H. M., Asaad, G. F., Ogaly, H. A., Hessin, A. F., Salama, A. A. A., Abd El-Rahman, S. S., Arbid, M. S., & Mohamed, M. A. E. (2021). The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats. PloS one, 16(12), e0260130. https://doi.org/10.1371/journal.pone.0260130
Abdel-Rahman, Rehab F, et al. "The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats." PloS one vol. 16,12 (2021): e0260130. doi: https://doi.org/10.1371/journal.pone.0260130
Abdel-Rahman RF, Fayed HM, Asaad GF, Ogaly HA, Hessin AF, Salama AAA, Abd El-Rahman SS, Arbid MS, Mohamed MAE. The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats. PLoS One. 2021 Dec 29;16(12):e0260130. doi: 10.1371/journal.pone.0260130. eCollection 2021. PMID: 34965258.
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Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children.

Journal of clinical pharmacology

Jiang S, Madrasi K, Samant T, Lagishetty C, Vozmediano V, Chiew A, Abdel-Rahman SM, James LP, Schmidt S.
PMID: 31802503
J Clin Pharmacol. 2019 Dec 04; doi: 10.1002/jcph.1555. Epub 2019 Dec 04.

Acetaminophen protein adducts (adducts) are a well-established biomarker to diagnose acetaminophen toxicity. To date, the quantitative relationship between acetaminophen exposure, which drives adduct formation, and adduct exposure remains to be established. Our study characterized the adduct formation and disposition...

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Jiang S, Madrasi K, Samant T, et al. Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children. J Clin Pharmacol. 2019;doi: 10.1002/jcph.1555.
Jiang, S., Madrasi, K., Samant, T., Lagishetty, C., Vozmediano, V., Chiew, A., Abdel-Rahman, S. M., James, L. P., & Schmidt, S. (2019). Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children. Journal of clinical pharmacology, . https://doi.org/10.1002/jcph.1555
Jiang, Sibo, et al. "Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children." Journal of clinical pharmacology vol. (2019). doi: https://doi.org/10.1002/jcph.1555
Jiang S, Madrasi K, Samant T, Lagishetty C, Vozmediano V, Chiew A, Abdel-Rahman SM, James LP, Schmidt S. Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children. J Clin Pharmacol. 2019 Dec 04; doi: 10.1002/jcph.1555. Epub 2019 Dec 04. PMID: 31802503; PMCID: PMC7643159.
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