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Showing 73 to 84 of 84 entries
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Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial.

Stem cell investigation

Jørgensen NG, Ahmad SM, Abildgaard N, Straten PT, Svane IM, Andersen MH, Knudsen LM.
PMID: 28078275
Stem Cell Investig. 2016 Dec 23;3:95. doi: 10.21037/sci.2016.11.09. eCollection 2016.

The B-cell lymphoma-2 (Bcl-2) family of proteins play a crucial role in multiple myeloma (MM), contributing to lacking apoptosis which is a hallmark of the disease. This makes the Bcl-2 proteins interesting targets for therapeutic peptide vaccination. We report...

Serum galectin-1 in patients with multiple myeloma: associations with survival, angiogenesis, and biomarkers of macrophage activation.

OncoTargets and therapy

Andersen MN, Ludvigsen M, Abildgaard N, Petruskevicius I, Hjortebjerg R, Bjerre M, Honoré B, Møller HJ, Andersen NF.
PMID: 28435287
Onco Targets Ther. 2017 Apr 04;10:1977-1982. doi: 10.2147/OTT.S124321. eCollection 2017.

Galectin-1 (Gal-1) is known to regulate cell signaling within the immune system and may be a target for new anticancer immune therapy. In patients with chronic lymphocytic leukemia (CLL) and classical Hodgkin lymphoma (cHL), high levels of Gal-1 within...

How to Measure the Intervention Process? An Assessment of Qualitative and Quantitative Approaches to Data Collection in the Process Evaluation of Organizational Interventions.

Frontiers in psychology

Abildgaard JS, Saksvik PØ, Nielsen K.
PMID: 27713707
Front Psychol. 2016 Sep 22;7:1380. doi: 10.3389/fpsyg.2016.01380. eCollection 2016.

Organizational interventions aiming at improving employee health and wellbeing have proven to be challenging to evaluate. To analyze intervention processes two methodological approaches have widely been used: quantitative (often questionnaire data), or qualitative (often interviews). Both methods are established...

Cardiovascular mortality after bilateral oophorectomy: a prospective cohort study.

Menopause (New York, N.Y.)

Olesen CS, Koch T, Uldbjerg CS, Gregersen LS, Christensen J, Dehlendorff C, Priskorn L, Wilson LF, Lim YH, Jørgensen JT, Andersen ZJ, Juul A, Abildgaard J, Hickey M, Bräuner EV.
PMID: 34726195
Menopause. 2021 Nov 01;29(1):28-34. doi: 10.1097/GME.0000000000001873.

OBJECTIVES: Bilateral oophorectomy permanently reduces endogenous estrogen exposure and may increase cardiovascular mortality in women. This study aimed to investigate the association between bilateral oophorectomy and cardiovascular mortality and whether this association was conditional on hysterectomy or on the...

Circulating trefoil factors in relation to lung cancer, age and lung function: a cross-sectional study in patients referred for suspected lung cancer.

Scandinavian journal of clinical and laboratory investigation

Samson MH, Abildgaard AM, Espelund U, Rasmussen TR, Folkersen B, Frystyk J, Nexo E.
PMID: 34242119
Scand J Clin Lab Invest. 2021 Oct;81(6):446-450. doi: 10.1080/00365513.2021.1943757. Epub 2021 Jul 09.

The trefoil factor family proteins: TFF1, TFF2 and TFF3 are secreted by epithelial cells in the respiratory tract. Here, we explore circulating concentrations of the trefoil factors in relation to lung cancer, age and lung function. We included 751...

COVID-19 vaccination in patients with multiple myeloma: a consensus of the European Myeloma Network.

The Lancet. Haematology

Ludwig H, Sonneveld P, Facon T, San-Miguel J, Avet-Loiseau H, Mohty M, Mateos MV, Moreau P, Cavo M, Pawlyn C, Zweegman S, Engelhardt M, Driessen C, Cook G, Dimopoulos MA, Gay F, Einsele H, Delforge M, Caers J, Weisel K, Jackson G, Garderet L, van de Donk N, Leleu X, Goldschmidt H, Beksac M, Nijhof I, Schreder M, Abildgaard N, Hajek R, Zojer N, Kastritis E, Broijl A, Schjesvold F, Boccadoro M, Terpos E.
PMID: 34756169
Lancet Haematol. 2021 Dec;8(12):e934-e946. doi: 10.1016/S2352-3026(21)00278-7. Epub 2021 Oct 28.

Patients with multiple myeloma frequently present with substantial immune impairment and an increased risk for infections and infection-related mortality. The risk for infection with SARS-CoV-2 virus and resulting mortality is also increased, emphasising the importance of protecting patients by...

Reference intervals for plasma vitamin B12 and plasma/serum methylmalonic acid in Danish children, adults and elderly.

Clinica chimica acta; international journal of clinical chemistry

Abildgaard A, Knudsen CS, Hoejskov CS, Greibe E, Parkner T.
PMID: 34942168
Clin Chim Acta. 2022 Jan 15;525:62-68. doi: 10.1016/j.cca.2021.12.015. Epub 2021 Dec 21.

BACKGROUND: Plasma/serum vitamin B12 (B12) is often used to screen for B12 deficiency complemented with analysis of methylmalonic acid (MMA) in case of low B12. The concentration of both analytes likely depends on age, and we, therefore, aimed at...

Correlation of whole-bone marrow dual-time-point .

American journal of nuclear medicine and molecular imaging

Zirakchian Zadeh M, Raynor WY, Østergaard B, Hess S, Yellanki DP, Ayubcha C, Mehdizadeh Seraj S, Acosta-Montenegro O, Borja AJ, Gerke O, Werner TJ, Zhuang H, Revheim ME, Abildgaard N, Høilund-Carlsen PF, Alavi A.
PMID: 33224622
Am J Nucl Med Mol Imaging. 2020 Oct 15;10(5):257-264. eCollection 2020.

The practical application of dual-time-point-imaging (DTPI) technique still remains controversial. One of the issues is that current parameters of DTPI quantification suffer from some deficiencies, mainly limited sampling of the diseased sites by confining measurements to specific locations. We...

Assessment of atherosclerosis in multiple myeloma and smoldering myeloma patients using .

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Arani LS, Zirakchian Zadeh M, Saboury B, Revheim ME, Øestergaard B, Borja AJ, Samadi Samarin D, Mehdizadeh Seraj S, Kalbush E, Ayubcha C, Morris MA, Werner TJ, Abildgaard N, Høilund-Carlsen PF, Alavi A.
PMID: 33389640
J Nucl Cardiol. 2021 Jan 03; doi: 10.1007/s12350-020-02446-0. Epub 2021 Jan 03.

BACKGROUND: To compare the NaF uptake in the thoracic aorta and whole heart, as an early indicator of atherosclerosis, in multiple myeloma (MM) and smoldering multiple myeloma (SMM) patients with a healthy control (HC) group.METHODS: Forty-four untreated myeloma patients...

The activated partial thromboplastin time may not reveal even severe fibrinogen deficiency.

Clinical chemistry and laboratory medicine

Abildgaard A, Hvas AM.
PMID: 33544482
Clin Chem Lab Med. 2021 Jan 28;59(7):e297-e300. doi: 10.1515/cclm-2020-1626. Print 2021 Jun 25.

No abstract available.

Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A Post Hoc Analysis of the U-TURN Trial.

Medicine and science in sports and exercise

Abildgaard J, Johansen MY, Skov-Jeppesen K, Andersen LB, Karstoft K, Hansen KB, Hartmann B, Holst JJ, Pedersen BK, Ried-Larsen M.
PMID: 34431828
Med Sci Sports Exerc. 2022 Jan 01;54(1):38-46. doi: 10.1249/MSS.0000000000002776.

INTRODUCTION/PURPOSE: The increased risk of fractures with type 2 diabetes (T2D) is suggested to be caused by decreased bone turnover. Current international guidelines recommend lifestyle modifications, including exercise, as first-line treatment for T2D. The aim of this study was...

Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A Post Hoc Analysis of the U-TURN Trial.

Medicine and science in sports and exercise

Abildgaard J, Johansen MY, Skov-Jeppesen K, Andersen LB, Karstoft K, Hansen KB, Hartmann B, Holst JJ, Pedersen BK, Ried-Larsen M.
PMID: 34431828
Med Sci Sports Exerc. 2022 Jan 01;54(1):38-46. doi: 10.1249/MSS.0000000000002776.

INTRODUCTION/PURPOSE: The increased risk of fractures with type 2 diabetes (T2D) is suggested to be caused by decreased bone turnover. Current international guidelines recommend lifestyle modifications, including exercise, as first-line treatment for T2D. The aim of this study was...

Showing 73 to 84 of 84 entries