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Showing 9985 to 9996 of 13458 entries
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Analyzing Twitter chatter about tobacco use within intoxication-related contexts of alcohol use: "Can someone tell me why nicotine is so fire when you're drunk?".

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Russell AM, Colditz JB, Barry AE, Davis RE, Shields S, Ortega JM, Primack B.
PMID: 34562100
Nicotine Tob Res. 2021 Sep 25; doi: 10.1093/ntr/ntab195. Epub 2021 Sep 25.

INTRODUCTION: Alcohol and tobacco are commonly used together. Social influences within online social networking platforms contribute to youth and young adult substance use behaviors. This study used a sample of alcohol- and tobacco-related tweets to evaluate: (1) sentiment toward...

Genome wide DNA methylation landscape reveals glioblastoma's influence on epigenetic changes in tumor infiltrating CD4+ T cells.

Oncotarget

Bam M, Chintala S, Fetcko K, Williamsen BC, Siraj S, Liu S, Wan J, Xuei X, Liu Y, Leibold AT, Dey M.
PMID: 34012510
Oncotarget. 2021 May 11;12(10):967-981. doi: 10.18632/oncotarget.27955. eCollection 2021 May 11.

CD4+ helper T (Th) cells play a critical role in shaping anti-tumor immunity by virtue of their ability to differentiate into multiple lineages in response to environmental cues. Various CD4+ lineages can orchestrate a broad range of effector activities...

SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain.

The Biochemical journal

Needham PG, Goeckeler-Fried JL, Zhang C, Sun Z, Wetzel AR, Bertrand CA, Brodsky JL.
PMID: 34821356
Biochem J. 2021 Dec 22;478(24):4203-4220. doi: 10.1042/BCJ20210644.

SLC26A9, a member of the solute carrier protein family, transports chloride ions across various epithelia. SLC26A9 also associates with other ion channels and transporters linked to human health, and in some cases these heterotypic interactions are essential to support...

A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma.

Cell reports

Milon B, Shulman ED, So KS, Cederroth CR, Lipford EL, Sperber M, Sellon JB, Sarlus H, Pregernig G, Shuster B, Song Y, Mitra S, Orvis J, Margulies Z, Ogawa Y, Shults C, Depireux DA, Palermo AT, Canlon B, Burns J, Elkon R, Hertzano R.
PMID: 34592158
Cell Rep. 2021 Sep 28;36(13):109758. doi: 10.1016/j.celrep.2021.109758.

Noise-induced hearing loss (NIHL) results from a complex interplay of damage to the sensory cells of the inner ear, dysfunction of its lateral wall, axonal retraction of type 1C spiral ganglion neurons, and activation of the immune response. We...

Author Correction: A molecular single-cell lung atlas of lethal COVID-19.

Nature

Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro DT, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy N, Suárez-Fariñas M, Bakhoum SF, Bram Y, Borczuk A, Guo XV, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Tsai EJ, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J, Izar B.
PMID: 34625743
Nature. 2021 Oct;598(7882):E2. doi: 10.1038/s41586-021-03921-5.

No abstract available.

Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.

Oncogene

Pietrobono S, Gaudio E, Gagliardi S, Zitani M, Carrassa L, Migliorini F, Petricci E, Manetti F, Makukhin N, Bond AG, Paradise BD, Ciulli A, Fernandez-Zapico ME, Bertoni F, Stecca B.
PMID: 33958721
Oncogene. 2021 Jun;40(22):3799-3814. doi: 10.1038/s41388-021-01783-9. Epub 2021 May 06.

Despite the development of new targeted and immune therapies, the prognosis of metastatic melanoma remains bleak. Therefore, it is critical to better understand the mechanisms controlling advanced melanoma to develop more effective treatment regimens. Hedgehog/GLI (HH/GLI) signaling inhibitors targeting...

Youth Sport and COVID-19: Contextual, Methodological, and Practical Considerations.

Frontiers in sports and active living

Kelly AL, Erickson K, Pierce S, Turnnidge J.
PMID: 33345153
Front Sports Act Living. 2020 Oct 09;2:584252. doi: 10.3389/fspor.2020.584252. eCollection 2020.

No abstract available.

Atomic-scale visualization of topological spin textures in the chiral magnet MnGe.

Science (New York, N.Y.)

Repicky J, Wu PK, Liu T, Corbett JP, Zhu T, Cheng S, Ahmed AS, Takeuchi N, Guerrero-Sanchez J, Randeria M, Kawakami RK, Gupta JA.
PMID: 34914516
Science. 2021 Dec 17;374(6574):1484-1487. doi: 10.1126/science.abd9225. Epub 2021 Dec 16.

[Figure: see text].

Translating known drivers of COVID-19 disease severity to design better SARS-CoV-2 vaccines.

Current opinion in virology

Pelletier AN, Sekaly RP, Tomalka JA.
PMID: 34902803
Curr Opin Virol. 2021 Dec 10;52:89-101. doi: 10.1016/j.coviro.2021.11.012. Epub 2021 Dec 10.

The SARS-CoV-2 pandemic has highlighted how an emergent disease can spread globally and how vaccines are once again the most important public health policy to combat infectious disease. Despite promising initial protection, the rise of new viral variants calls...

Is the affordable care act medicaid expansion associated with receipt of heart failure guideline-directed medical therapy by race and ethnicity?.

American heart journal

Breathett KK, Xu H, Sweitzer NK, Calhoun E, Matsouaka RA, Yancy CW, Fonarow GC, DeVore AD, Bhatt DL, Peterson PN.
PMID: 34813771
Am Heart J. 2021 Nov 20;244:135-148. doi: 10.1016/j.ahj.2021.11.011. Epub 2021 Nov 20.

BACKGROUND: Uninsurance is a known contributor to racial/ethnic health inequities. Insurance is often needed for prescriptions and follow-up appointments. Therefore, we determined whether the Affordable Care Act(ACA) Medicaid Expansion was associated with increased receipt of guideline-directed medical treatment(GDMT) at...

In Vivo Porcine Aged Deep Vein Thrombosis Model for Testing Ultrasound-based Thrombolysis Techniques.

Ultrasound in medicine & biology

Stocker GE, Shi J, Ives K, Maxwell AD, Dayton PA, Jiang X, Xu Z, Owens GE.
PMID: 34593277
Ultrasound Med Biol. 2021 Dec;47(12):3447-3457. doi: 10.1016/j.ultrasmedbio.2021.08.017. Epub 2021 Sep 28.

As blood clots age, many thrombolytic techniques become less effective. To fully evaluate these techniques for potential clinical use, a large animal aged-clot model is needed. Previous minimally invasive attempts to allow clots to age in an in vivo...

REBOA placement for placenta accreta spectrum: patient selection and utilization.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Whittington JR, Pagan ME, Sharawi N, Hughes DS, Sandlin AT.
PMID: 33926349
J Matern Fetal Neonatal Med. 2021 Apr 29;1-2. doi: 10.1080/14767058.2021.1914580. Epub 2021 Apr 29.

No abstract available.

Showing 9985 to 9996 of 13458 entries