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Showing 25 to 36 of 46 entries
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Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia.

Scientific reports

Al-Mekhlafi HM, Madkhali AM, Abdulhaq AA, Atroosh WM, Ghzwani AH, Zain KA, Ghailan KY, Hamali HA, Mobarki AA, Alharazi TH, Eisa ZM, Lau YL.
PMID: 35017593
Sci Rep. 2022 Jan 11;12(1):517. doi: 10.1038/s41598-021-04450-x.

A total of 227 Plasmodium falciparum isolates from Jazan region, southwestern Saudi Arabia were amplified for the P. falciparum multi-drug resistance 1 (pfmdr1) gene to detect point mutations 11 years after the introduction of artemisinin-based combination therapy (ACT) in...

Targeting focal ischemic and hemorrhagic stroke neuroprotection: Current prospects for local hypothermia.

Journal of neurochemistry

Liddle LJ, Kalisvaart ACJ, Abrahart AH, Almekhlafi M, Demchuk A, Colbourne F.
PMID: 34496050
J Neurochem. 2021 Sep 08; doi: 10.1111/jnc.15508. Epub 2021 Sep 08.

Therapeutic hypothermia (TH) has applications dating back millennia. In modern history, however, TH saw its importation into medical practice where investigations have demonstrated that TH is efficacious in ischemic insults, notably cardiac arrest and hypoxic-ischemic encephalopathy. As well, studies...

Nonstandard finite difference method for solving complex-order fractional Burgers' equations.

Journal of advanced research

Sweilam NH, Al-Mekhlafi SM, Baleanu D.
PMID: 32922970
J Adv Res. 2020 May 15;25:19-29. doi: 10.1016/j.jare.2020.04.007. eCollection 2020 Sep.

The aim of this work is to present numerical treatments to a complex order fractional nonlinear one-dimensional problem of Burgers' equations. A new parameter

Larvicidal Activities of Indigenous .

Journal of arthropod-borne diseases

Ahmed AM, Hussein HI, El-Kersh TA, Al-Sheikh YA, Ayaad TH, El-Sadawy HA, Al-Mekhlafi FA, Ibrahim MS, Al-Tamimi J, Nasr FA.
PMID: 29062851
J Arthropod Borne Dis. 2017 May 27;11(2):260-277. eCollection 2017 Jun.

BACKGROUND: The incidence of mosquito-borne diseases and the resistance of mosquitoes to conventional pesticides have recently caused a panic to the authorities in the endemic countries. This study was conducted to identify native larvicidal biopesticides against METHODS: Larvicidal activities...

Optimal control for a fractional tuberculosis infection model including the impact of diabetes and resistant strains.

Journal of advanced research

Sweilam NH, Al-Mekhlafi SM, Baleanu D.
PMID: 31193340
J Adv Res. 2019 Jan 19;17:125-137. doi: 10.1016/j.jare.2019.01.007. eCollection 2019 May.

The objective of this paper is to study the optimal control problem for the fractional tuberculosis (TB) infection model including the impact of diabetes and resistant strains. The governed model consists of 14 fractional-order (FO) equations. Four control variables...

Utility of Vessel Wall Imaging in Suspected CNS Vasculitis with Normal Routine Workup.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Wadhwa A, Hahn C, Fifi-Mah A, Almekhlafi M.
PMID: 33947490
Can J Neurol Sci. 2021 May 05;1-3. doi: 10.1017/cjn.2021.101. Epub 2021 May 05.

No abstract available.

A hybrid stochastic fractional order Coronavirus (2019-nCov) mathematical model.

Chaos, solitons, and fractals

Sweilam NH, Al-Mekhlafi SM, Baleanu D.
PMID: 33589855
Chaos Solitons Fractals. 2021 Apr;145:110762. doi: 10.1016/j.chaos.2021.110762. Epub 2021 Feb 10.

In this paper, a new stochastic fractional Coronavirus (2019-nCov) model with modified parameters is presented. The proposed stochastic COVID-19 model describes well the real data of daily confirmed cases in Wuhan. Moreover, a novel fractional order operator is introduced,...

Awareness on Teratogenic Effects of Isotretinoin and Compliance with Precautionary Measures among Women of Childbearing Age in Makkah Province, Saudi Arabia.

Obstetrics and gynecology international

Al-Mekhlafi R, Attiyah RE, Haddad YR, Salah LA.
PMID: 33936210
Obstet Gynecol Int. 2021 Apr 10;2021:9966300. doi: 10.1155/2021/9966300. eCollection 2021.

Acne vulgaris ranks among the most common dermatologic conditions encountered during adolescence up to adulthood. For moderate to severe cases of acne, isotretinoin is indicated as it is considered the most efficacious medication against acne. However, isotretinoin use is...

Correction to: Brevibacillus laterosporus isolated from the digestive tract of honeybees has high antimicrobial activity and promotes growth and productivity of honeybee's colonies.

Environmental science and pollution research international

Khaled JM, Al-Mekhlafi FA, Mothana RA, Alharbi NS, Alzaharni KE, Sharafaddin AH, Kadaikunnan S, Alobaidi AS, Bayaqoob NI, Govindarajan M, Benelli G.
PMID: 29987465
Environ Sci Pollut Res Int. 2018 Aug;25(24):24516. doi: 10.1007/s11356-018-2721-8.

The original publication of this paper contains a mistake. The correct affiliation no. 3 is shown in this paper.

On the optimal control of coronavirus (2019-nCov) mathematical model; a numerical approach.

Advances in difference equations

Sweilam NH, Al-Mekhlafi SM, Albalawi AO, Baleanu D.
PMID: 32994791
Adv Differ Equ. 2020;2020(1):528. doi: 10.1186/s13662-020-02982-6. Epub 2020 Sep 25.

In this paper, a novel coronavirus (2019-nCov) mathematical model with modified parameters is presented. This model consists of six nonlinear fractional order differential equations. Optimal control of the suggested model is the main objective of this work. Two control...

Epidemiological screening and serotyping analysis of dengue fever in the Southwestern region of Saudi Arabia.

Saudi journal of biological sciences

Alshabi A, Marwan A, Fatima N, Madkhali AM, Alnagai F, Alhazmi A, Al-Mekhlafi HM, Abdulhaq AA, Ghailan KY, Sali A, Refaei T.
PMID: 35002410
Saudi J Biol Sci. 2022 Jan;29(1):204-210. doi: 10.1016/j.sjbs.2021.08.070. Epub 2021 Aug 26.

Dengue is an acute systemic viral disease that has been developed globally in both chronic and epidemic transmission periods. Dengue virus (DENV) is a member of the Flavivirus genus of the Flaviviridae family, which endangers public health. Limited studies...

Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials.

Malaria journal

Atroosh WM, Lau YL, Snounou G, Azzani M, Al-Mekhlafi HM.
PMID: 34983529
Malar J. 2022 Jan 04;21(1):2. doi: 10.1186/s12936-021-04014-4.

BACKGROUND: Genotyping of the three Plasmodium falciparum polymorphic genes, msp1, msp2 and glurp, has been adopted as a standard strategy to distinguish recrudescence from new infection in drug efficacy clinical trials. However, the suitability of a particular gene is...

Showing 25 to 36 of 46 entries