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Showing 1225 to 1234 of 1234 entries
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Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy.

Brain : a journal of neurology

VerPlank JJS, Gawron J, Silvestri NJ, Feltri ML, Wrabetz L, Goldberg AL.
PMID: 34382059
Brain. 2021 Aug 11; doi: 10.1093/brain/awab249. Epub 2021 Aug 11.

Agents that raise cGMP by activating Protein Kinase G increase 26S proteasome activities, protein ubiquitination, and degradation of misfolded proteins. Therefore, they may be useful in treating neurodegenerative and other diseases caused by an accumulation of misfolded proteins. Mutations...

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VerPlank JJS, Gawron J, Silvestri NJ, et al. Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy. Brain. 2021;doi: 10.1093/brain/awab249.
VerPlank, J. J. S., Gawron, J., Silvestri, N. J., Feltri, M. L., Wrabetz, L., & Goldberg, A. L. (2021). Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy. Brain : a journal of neurology, . https://doi.org/10.1093/brain/awab249
VerPlank, Jordan J S, et al. "Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy." Brain : a journal of neurology vol. (2021). doi: https://doi.org/10.1093/brain/awab249
VerPlank JJS, Gawron J, Silvestri NJ, Feltri ML, Wrabetz L, Goldberg AL. Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy. Brain. 2021 Aug 11; doi: 10.1093/brain/awab249. Epub 2021 Aug 11. PMID: 34382059.
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Kidney tubule health, mineral metabolism, and adverse events in persons with CKD in SPRINT.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Ascher SB, Scherzer R, Estrella MM, Berry JD, de Lemos JA, Jotwani VK, Garimella PS, Malhotra R, Bullen AL, Katz R, Ambrosius WT, Cheung AK, Chonchol M, Killeen AA, Ix JH, Shlipak MG.
PMID: 34473302
Nephrol Dial Transplant. 2021 Sep 02; doi: 10.1093/ndt/gfab255. Epub 2021 Sep 02.

BACKGROUND: Measures of kidney tubule health are risk markers for acute kidney injury (AKI) in persons with chronic kidney disease (CKD) during hypertension treatment, but their associations with other adverse events (AEs) are unknown.METHODS: Among 2,377 Systolic Blood Pressure...

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Ascher SB, Scherzer R, Estrella MM, et al. Kidney tubule health, mineral metabolism, and adverse events in persons with CKD in SPRINT. Nephrol Dial Transplant. 2021;doi: 10.1093/ndt/gfab255.
Ascher, S. B., Scherzer, R., Estrella, M. M., Berry, J. D., de Lemos, J. A., Jotwani, V. K., Garimella, P. S., Malhotra, R., Bullen, A. L., Katz, R., Ambrosius, W. T., Cheung, A. K., Chonchol, M., Killeen, A. A., Ix, J. H., Shlipak, M. G. (2021). Kidney tubule health, mineral metabolism, and adverse events in persons with CKD in SPRINT. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, . https://doi.org/10.1093/ndt/gfab255
Ascher, Simon B, et al. "Kidney tubule health, mineral metabolism, and adverse events in persons with CKD in SPRINT." Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association vol. (2021). doi: https://doi.org/10.1093/ndt/gfab255
Ascher SB, Scherzer R, Estrella MM, Berry JD, de Lemos JA, Jotwani VK, Garimella PS, Malhotra R, Bullen AL, Katz R, Ambrosius WT, Cheung AK, Chonchol M, Killeen AA, Ix JH, Shlipak MG. Kidney tubule health, mineral metabolism, and adverse events in persons with CKD in SPRINT. Nephrol Dial Transplant. 2021 Sep 02; doi: 10.1093/ndt/gfab255. Epub 2021 Sep 02. PMID: 34473302.
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Memristive Behavior of Mixed Oxide Nanocrystal Assemblies.

ACS applied materials & interfaces

Zhou Z, López-Domínguez P, Abdullah M, Barber DM, Meng X, Park J, Van Driessche I, Schiffman JD, Crosby AJ, Kittilstved KR, Nonnenmann SS.
PMID: 33938727
ACS Appl Mater Interfaces. 2021 May 12;13(18):21635-21644. doi: 10.1021/acsami.1c03722. Epub 2021 May 03.

Recent advances in memristive nanocrystal assemblies leverage controllable colloidal chemistry to induce a broad range of defect-mediated electrochemical reactions, switching phenomena, and modulate active parameters. The sample geometry of virtually all resistive switching studies involves thin film layers comprising...

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Zhou Z, López-Domínguez P, Abdullah M, et al. Memristive Behavior of Mixed Oxide Nanocrystal Assemblies. ACS Appl Mater Interfaces. 2021;13(18):21635-21644doi: 10.1021/acsami.1c03722.
Zhou, Z., López-Domínguez, P., Abdullah, M., Barber, D. M., Meng, X., Park, J., Van Driessche, I., Schiffman, J. D., Crosby, A. J., Kittilstved, K. R., & Nonnenmann, S. S. (2021). Memristive Behavior of Mixed Oxide Nanocrystal Assemblies. ACS applied materials & interfaces, 13(18), 21635-21644. https://doi.org/10.1021/acsami.1c03722
Zhou, Zimu, et al. "Memristive Behavior of Mixed Oxide Nanocrystal Assemblies." ACS applied materials & interfaces vol. 13,18 (2021): 21635-21644. doi: https://doi.org/10.1021/acsami.1c03722
Zhou Z, López-Domínguez P, Abdullah M, Barber DM, Meng X, Park J, Van Driessche I, Schiffman JD, Crosby AJ, Kittilstved KR, Nonnenmann SS. Memristive Behavior of Mixed Oxide Nanocrystal Assemblies. ACS Appl Mater Interfaces. 2021 May 12;13(18):21635-21644. doi: 10.1021/acsami.1c03722. Epub 2021 May 03. PMID: 33938727.
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Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Zhang X, Wolff MS, Shen J, Parada H, Santella RM, Neugut AI, Chen J, Teitelbaum SL.
PMID: 34697054
Cancer Epidemiol Biomarkers Prev. 2021 Oct 25; doi: 10.1158/1055-9965.EPI-21-0830. Epub 2021 Oct 25.

BACKGROUND: Phthalates and phenols from the environment have been inconsistently associated with breast cancer risk or mortality. Studies on the potential modifying role of leukocyte telomere length (LTL), a biomarker of biological aging, on these associations are lacking.METHODS: We...

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Zhang X, Wolff MS, Shen J, et al. Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer Epidemiol Biomarkers Prev. 2021;doi: 10.1158/1055-9965.EPI-21-0830.
Zhang, X., Wolff, M. S., Shen, J., Parada, H., Santella, R. M., Neugut, A. I., Chen, J., & Teitelbaum, S. L. (2021). Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, . https://doi.org/10.1158/1055-9965.EPI-21-0830
Zhang, Xueying, et al. "Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. (2021). doi: https://doi.org/10.1158/1055-9965.EPI-21-0830
Zhang X, Wolff MS, Shen J, Parada H, Santella RM, Neugut AI, Chen J, Teitelbaum SL. Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer Epidemiol Biomarkers Prev. 2021 Oct 25; doi: 10.1158/1055-9965.EPI-21-0830. Epub 2021 Oct 25. PMID: 34697054.
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ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib.

Pharmacological research

Wang Y, Sparidans RW, Potters S, Lebre MC, Beijnen JH, Schinkel AH.
PMID: 34450308
Pharmacol Res. 2021 Oct;172:105850. doi: 10.1016/j.phrs.2021.105850. Epub 2021 Aug 25.

BACKGROUND AND PURPOSE: Pralsetinib is an FDA-approved oral small-molecule inhibitor for treatment of rearranged during transfection (RET) proto-oncogene fusion-positive non-small cell lung cancer. We investigated how the efflux transporters ABCB1 and ABCG2, the SLCO1A/1B uptake transporters and the drug-metabolizing...

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Wang Y, Sparidans RW, Potters S, et al. ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib. Pharmacol Res. 2021;172:105850doi: 10.1016/j.phrs.2021.105850.
Wang, Y., Sparidans, R. W., Potters, S., Lebre, M. C., Beijnen, J. H., & Schinkel, A. H. (2021). ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib. Pharmacological research, 172105850. https://doi.org/10.1016/j.phrs.2021.105850
Wang, Yaogeng, et al. "ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib." Pharmacological research vol. 172 (2021): 105850. doi: https://doi.org/10.1016/j.phrs.2021.105850
Wang Y, Sparidans RW, Potters S, Lebre MC, Beijnen JH, Schinkel AH. ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib. Pharmacol Res. 2021 Oct;172:105850. doi: 10.1016/j.phrs.2021.105850. Epub 2021 Aug 25. PMID: 34450308.
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Characterization of synthetic riboswitch in cell-free protein expression systems.

RNA biology

Chushak Y, Harbaugh S, Zimlich K, Alfred B, Chávez J, Kelley-Loughnane N.
PMID: 33427029
RNA Biol. 2021 Nov;18(11):1727-1738. doi: 10.1080/15476286.2020.1868149. Epub 2021 Jan 11.

Riboswitches are RNA-based regulatory elements that utilize ligand-induced structural changes in the 5'-untranslated region of mRNA to regulate the expression of associated genes. The majority of synthetic riboswitches have been selected and tested in cell-based systems. Cell-free protein expression...

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Chushak Y, Harbaugh S, Zimlich K, et al. Characterization of synthetic riboswitch in cell-free protein expression systems. RNA Biol. 2021;18(11):1727-1738doi: 10.1080/15476286.2020.1868149.
Chushak, Y., Harbaugh, S., Zimlich, K., Alfred, B., Chávez, J., & Kelley-Loughnane, N. (2021). Characterization of synthetic riboswitch in cell-free protein expression systems. RNA biology, 18(11), 1727-1738. https://doi.org/10.1080/15476286.2020.1868149
Chushak, Yaroslav, et al. "Characterization of synthetic riboswitch in cell-free protein expression systems." RNA biology vol. 18,11 (2021): 1727-1738. doi: https://doi.org/10.1080/15476286.2020.1868149
Chushak Y, Harbaugh S, Zimlich K, Alfred B, Chávez J, Kelley-Loughnane N. Characterization of synthetic riboswitch in cell-free protein expression systems. RNA Biol. 2021 Nov;18(11):1727-1738. doi: 10.1080/15476286.2020.1868149. Epub 2021 Jan 11. PMID: 33427029; PMCID: PMC8583236.
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Reducing non-melanoma skin cancer risk in renal transplant recipients.

Nephrology (Carlton, Vic.)

Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK.
PMID: 34240786
Nephrology (Carlton). 2021 Nov;26(11):907-919. doi: 10.1111/nep.13939. Epub 2021 Jul 28.

With an increasing number of renal transplant recipients (RTRs) and improving patient survival, a higher incidence of non-melanoma skin cancer (NMSC) has been observed. NMSC in RTRs are often more numerous and biologically more aggressive than the general population,...

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Thet Z, Lam AK, Ranganathan D, et al. Reducing non-melanoma skin cancer risk in renal transplant recipients. Nephrology (Carlton). 2021;26(11):907-919doi: 10.1111/nep.13939.
Thet, Z., Lam, A. K., Ranganathan, D., Aung, S. Y., Han, T., & Khoo, T. K. (2021). Reducing non-melanoma skin cancer risk in renal transplant recipients. Nephrology (Carlton, Vic.), 26(11), 907-919. https://doi.org/10.1111/nep.13939
Thet, Zaw, et al. "Reducing non-melanoma skin cancer risk in renal transplant recipients." Nephrology (Carlton, Vic.) vol. 26,11 (2021): 907-919. doi: https://doi.org/10.1111/nep.13939
Thet Z, Lam AK, Ranganathan D, Aung SY, Han T, Khoo TK. Reducing non-melanoma skin cancer risk in renal transplant recipients. Nephrology (Carlton). 2021 Nov;26(11):907-919. doi: 10.1111/nep.13939. Epub 2021 Jul 28. PMID: 34240786.
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Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Zhang X, Wolff MS, Shen J, Parada H, Santella RM, Neugut AI, Chen J, Teitelbaum SL.
PMID: 34697054
Cancer Epidemiol Biomarkers Prev. 2022 Jan;31(1):117-123. doi: 10.1158/1055-9965.EPI-21-0830. Epub 2021 Oct 25.

BACKGROUND: Phthalates and phenols from the environment have been inconsistently associated with breast cancer risk or mortality. Studies on the potential modifying role of leukocyte telomere length (LTL), a biomarker of biological aging, on these associations are lacking.METHODS: We...

Cite
Zhang X, Wolff MS, Shen J, et al. Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer Epidemiol Biomarkers Prev. 2021;31(1):117-123doi: 10.1158/1055-9965.EPI-21-0830.
Zhang, X., Wolff, M. S., Shen, J., Parada, H., Santella, R. M., Neugut, A. I., Chen, J., & Teitelbaum, S. L. (2022). Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 31(1), 117-123. https://doi.org/10.1158/1055-9965.EPI-21-0830
Zhang, Xueying, et al. "Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 31,1 (2022): 117-123. doi: https://doi.org/10.1158/1055-9965.EPI-21-0830
Zhang X, Wolff MS, Shen J, Parada H, Santella RM, Neugut AI, Chen J, Teitelbaum SL. Phthalates and Phenols, Leukocyte Telomere Length, and Breast Cancer Risk and Mortality in the Long Island Breast Cancer Study Project. Cancer Epidemiol Biomarkers Prev. 2022 Jan;31(1):117-123. doi: 10.1158/1055-9965.EPI-21-0830. Epub 2021 Oct 25. PMID: 34697054; PMCID: PMC8755624.
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Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting.

Human pathology

Lam AK, Bourke MJ, Chen R, Fiocca R, Fujishima F, Fujii S, Jansen M, Kumarasinghe P, Langer R, Law S, Meijer SL, Muldoon C, Novelli M, Shi C, Tang L, Nagtegaal ID.
PMID: 33992659
Hum Pathol. 2021 Aug;114:54-65. doi: 10.1016/j.humpath.2021.05.003. Epub 2021 May 13.

BACKGROUND AND OBJECTIVES: A standardized data set for esophageal carcinoma pathology reporting was developed based on the approach of the International Collaboration on Cancer Reporting (ICCR) for the purpose of improving cancer patient outcomes and international benchmarking in cancer...

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Lam AK, Bourke MJ, Chen R, et al. Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Hum Pathol. 2021;114:54-65doi: 10.1016/j.humpath.2021.05.003.
Lam, A. K., Bourke, M. J., Chen, R., Fiocca, R., Fujishima, F., Fujii, S., Jansen, M., Kumarasinghe, P., Langer, R., Law, S., Meijer, S. L., Muldoon, C., Novelli, M., Shi, C., Tang, L., & Nagtegaal, I. D. (2021). Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Human pathology, 11454-65. https://doi.org/10.1016/j.humpath.2021.05.003
Lam, Alfred K, et al. "Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting." Human pathology vol. 114 (2021): 54-65. doi: https://doi.org/10.1016/j.humpath.2021.05.003
Lam AK, Bourke MJ, Chen R, Fiocca R, Fujishima F, Fujii S, Jansen M, Kumarasinghe P, Langer R, Law S, Meijer SL, Muldoon C, Novelli M, Shi C, Tang L, Nagtegaal ID. Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Hum Pathol. 2021 Aug;114:54-65. doi: 10.1016/j.humpath.2021.05.003. Epub 2021 May 13. PMID: 33992659.
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Development and Validation of a Deep Learning Model Using Convolutional Neural Networks to Identify Scaphoid Fractures in Radiographs.

JAMA network open

Yoon AP, Lee YL, Kane RL, Kuo CF, Lin C, Chung KC.
PMID: 33956133
JAMA Netw Open. 2021 May 03;4(5):e216096. doi: 10.1001/jamanetworkopen.2021.6096.

IMPORTANCE: Scaphoid fractures are the most common carpal fracture, but as many as 20% are not visible (ie, occult) in the initial injury radiograph; untreated scaphoid fractures can lead to degenerative wrist arthritis and debilitating pain, detrimentally affecting productivity...

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Yoon AP, Lee YL, Kane RL, et al. Development and Validation of a Deep Learning Model Using Convolutional Neural Networks to Identify Scaphoid Fractures in Radiographs. JAMA Netw Open. 2021;4(5):e216096doi: 10.1001/jamanetworkopen.2021.6096.
Yoon, A. P., Lee, Y. L., Kane, R. L., Kuo, C. F., Lin, C., & Chung, K. C. (2021). Development and Validation of a Deep Learning Model Using Convolutional Neural Networks to Identify Scaphoid Fractures in Radiographs. JAMA network open, 4(5), e216096. https://doi.org/10.1001/jamanetworkopen.2021.6096
Yoon, Alfred P, et al. "Development and Validation of a Deep Learning Model Using Convolutional Neural Networks to Identify Scaphoid Fractures in Radiographs." JAMA network open vol. 4,5 (2021): e216096. doi: https://doi.org/10.1001/jamanetworkopen.2021.6096
Yoon AP, Lee YL, Kane RL, Kuo CF, Lin C, Chung KC. Development and Validation of a Deep Learning Model Using Convolutional Neural Networks to Identify Scaphoid Fractures in Radiographs. JAMA Netw Open. 2021 May 03;4(5):e216096. doi: 10.1001/jamanetworkopen.2021.6096. PMID: 33956133; PMCID: PMC8103226.
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Showing 1225 to 1234 of 1234 entries