Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 13 to 18 of 18 entries
Sorted by: Best Match Show Resources per page
Dynamic variability in SHP-1 abundance determines natural killer cell responsiveness.

Science signaling

Wu Z, Park S, Lau CM, Zhong Y, Sheppard S, Sun JC, Das J, Altan-Bonnet G, Hsu KC.
PMID: 34752140
Sci Signal. 2021 Nov 09;14(708):eabe5380. doi: 10.1126/scisignal.abe5380. Epub 2021 Nov 09.

[Figure: see text].

A New Infectious Unit: Extracellular Vesicles Carrying Virus Populations.

Annual review of cell and developmental biology

Kerviel A, Zhang M, Altan-Bonnet N.
PMID: 34270326
Annu Rev Cell Dev Biol. 2021 Oct 06;37:171-197. doi: 10.1146/annurev-cellbio-040621-032416. Epub 2021 Jul 16.

Viral egress and transmission have long been described to take place through single free virus particles. However, viruses can also shed into the environment and transmit as populations clustered inside extracellular vesicles (EVs), a process we had first called...

Correction: Annular PIP.

The Journal of experimental medicine

Le Floc'h A, Tanaka Y, Bantilan NS, Voisinne G, Altan-Bonnet G, Fukui Y, Huse M.
PMID: 28292823
J Exp Med. 2017 Apr 03;214(4):1203. doi: 10.1084/jem.2013132403102017c. Epub 2017 Mar 14.

No abstract available.

Dichotomy of cellular inhibition by small-molecule inhibitors revealed by single-cell analysis.

Nature communications

Vogel RM, Erez A, Altan-Bonnet G.
PMID: 27687249
Nat Commun. 2016 Sep 30;7:12428. doi: 10.1038/ncomms12428.

Despite progress in drug development, a quantitative and physiological understanding of how small-molecule inhibitors act on cells is lacking. Here, we measure the signalling and proliferative response of individual primary T-lymphocytes to a combination of antigen, cytokine and drug....

A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells.

Cell

Wong HS, Park K, Gola A, Baptista AP, Miller CH, Deep D, Lou M, Boyd LF, Rudensky AY, Savage PA, Altan-Bonnet G, Tsang JS, Germain RN.
PMID: 34157301
Cell. 2021 Jul 22;184(15):3981-3997.e22. doi: 10.1016/j.cell.2021.05.028. Epub 2021 Jun 21.

A fraction of mature T cells can be activated by peripheral self-antigens, potentially eliciting host autoimmunity. We investigated homeostatic control of self-activated T cells within unperturbed tissue environments by combining high-resolution multiplexed and volumetric imaging with computational modeling. In...

Luminal microvesicles uniquely influence translocating bacteria after SIV infection.

Mucosal immunology

Flynn JK, Langner CA, Karmele EP, Baker PJ, Pei L, Gorfu EG, Bochart RM, Santiana M, Smelkinson MG, Nutman TB, Altan-Bonnet N, Bosinger SE, Kelsall BL, Brenchley JM, Ortiz AM.
PMID: 33731830
Mucosal Immunol. 2021 Jul;14(4):937-948. doi: 10.1038/s41385-021-00393-8. Epub 2021 Mar 17.

Microbial translocation contributes to persistent inflammation in both treated and untreated HIV infection. Although translocation is due in part to a disintegration of the intestinal epithelial barrier, there is a bias towards the translocation of Proteobacteria. We hypothesized that...

Showing 13 to 18 of 18 entries