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Showing 445 to 455 of 455 entries
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Epistemic practices in Bio Art.

AI & society

Anker S.
PMID: 33584019
AI Soc. 2021 Feb 08;1-6. doi: 10.1007/s00146-021-01152-w. Epub 2021 Feb 08.

This paper addresses three aspects of Bio Art: iconography, artificial life, and wetware. The development of models for innovation require hybrid practices which generate knowledge through epistemic experimental practices. The intersection of art and the biological sciences contain both...

In vivo models of cardiac diseases: application to drug development and screening.

Expert opinion on drug discovery

Rokutan H, Anker SD, Springer J.
PMID: 22823972
Expert Opin Drug Discov. 2010 Jan;5(1):65-78. doi: 10.1517/17460440903460299.

Cardiac disease is the top cause of human mortality in the Western world. Current drug therapy for cardiac disease has been established via experimental studies using a variety of in vivo animal models. The purpose of this review is...

Prognostic Importance of NT-proBNP and Effect of Empagliflozin in the EMPEROR-Reduced Trial.

Journal of the American College of Cardiology

Januzzi JL, Zannad F, Anker SD, Butler J, Filippatos G, Pocock SJ, Ferreira JP, Sattar N, Verma S, Vedin O, Schnee J, Iwata T, Cotton D, Packer M.
PMID: 34556318
J Am Coll Cardiol. 2021 Sep 28;78(13):1321-1332. doi: 10.1016/j.jacc.2021.07.046.

BACKGROUND: The relationship between the benefits of empagliflozin in heart failure with reduced ejection fraction (HFrEF) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) has not been reported.OBJECTIVES: The authors sought to evaluate the relationship between NT-proBNP and empagliflozin effects in...

Empagliflozin Improves Cardiovascular and Renal Outcomes in Heart Failure Irrespective of Systolic Blood Pressure.

Journal of the American College of Cardiology

Böhm M, Anker SD, Butler J, Filippatos G, Ferreira JP, Pocock SJ, Mahfoud F, Brueckmann M, Jamal W, Ofstad AP, Schüler E, Ponikowski P, Wanner C, Zannad F, Packer M.
PMID: 34556320
J Am Coll Cardiol. 2021 Sep 28;78(13):1337-1348. doi: 10.1016/j.jacc.2021.07.049.

BACKGROUND: Empagliflozin reduces the risk of cardiovascular death or heart failure (HF) hospitalization in patients with reduced ejection fraction. Its interplay with systolic blood pressure (SBP) is not known.OBJECTIVES: The goal of this study was to evaluate the interplay...

Quantifying high flexion postures in occupational childcare as they relate to the potential for increased risk of knee osteoarthritis.

Ergonomics

Laudanski AF, Buchman-Pearle JM, Acker SM.
PMID: 34397308
Ergonomics. 2021 Aug 31;1-12. doi: 10.1080/00140139.2021.1969041. Epub 2021 Aug 31.

High knee flexion postures, despite their association with increased incidences of osteoarthritis, are frequently adopted in occupational childcare. This study sought to define and quantify high flexion postures typically adopted in childcare to evaluate any increased likelihood of knee...

CARDIOVASCULAR EFFECTS OF NON-INSULIN GLUCOSE-LOWERING AGENTS: A COMPREHENSIVE REVIEW OF TRIAL EVIDENCE AND POTENTIAL CARDIOPROTECTIVE MECHANISMS.

Cardiovascular research

Savarese G, Butler J, Lund LH, Bhatt DL, Anker SD.
PMID: 34390570
Cardiovasc Res. 2021 Aug 13; doi: 10.1093/cvr/cvab271. Epub 2021 Aug 13.

Type 2 diabetes mellitus (T2DM) is highly prevalent and associated with a 2-fold increased mortality, mostly explained by cardiovascular diseases. Trial evidence on older glucose-lowering agents such as metformin and sulfonylureas is limited in terms of cardiovascular efficacy. Since...

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2021.

Journal of cachexia, sarcopenia and muscle

von Haehling S, Coats AJS, Anker SD.
PMID: 34904399
J Cachexia Sarcopenia Muscle. 2021 Dec 13; doi: 10.1002/jcsm.12899. Epub 2021 Dec 13.

The Journal of Cachexia, Sarcopenia and Muscle (JCSM) aims to publish articles with relevance to wasting disorders and illnesses of the muscle in the broadest sense. In order to avoid publication of inappropriate articles and to avoid protracted disputes,...

Kidney Function After Initiation and Discontinuation of Empagliflozin in Patients With Heart Failure With and Without Type 2 Diabetes: Insights From the EMPERIAL Trials.

Circulation

Anker SD, Ponikowski P, Wanner C, Pfarr E, Hauske S, Peil B, Salsali A, Ritter I, Koitka-Weber A, Brueckmann M, Lindenfeld J, Abraham WT.
PMID: 34397263
Circulation. 2021 Oct 12;144(15):1265-1267. doi: 10.1161/CIRCULATIONAHA.121.054669. Epub 2021 Aug 16.

No abstract available.

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes.

The New England journal of medicine

Pitt B, Filippatos G, Agarwal R, Anker SD, Bakris GL, Rossing P, Joseph A, Kolkhof P, Nowack C, Schloemer P, Ruilope LM.
PMID: 34449181
N Engl J Med. 2021 Dec 09;385(24):2252-2263. doi: 10.1056/NEJMoa2110956. Epub 2021 Aug 28.

BACKGROUND: Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has favorable effects on cardiorenal outcomes in patients with predominantly stage 3 or 4 chronic kidney disease (CKD) with severely elevated albuminuria and type 2 diabetes. The use of finerenone in...

Finerenone and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Type 2 Diabetes.

Circulation

Filippatos G, Anker SD, Agarwal R, Pitt B, Ruilope LM, Rossing P, Kolkhof P, Schloemer P, Tornus I, Joseph A, Bakris GL.
PMID: 33198491
Circulation. 2021 Feb 09;143(6):540-552. doi: 10.1161/CIRCULATIONAHA.120.051898. Epub 2020 Nov 16.

BACKGROUND: The FIDELIO-DKD trial (Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease) evaluated the effect of the nonsteroidal, selective mineralocorticoid receptor antagonist finerenone on kidney and cardiovascular outcomes in patients with chronic kidney disease and...

Empagliflozin in the treatment of heart failure with reduced ejection fraction in addition to background therapies and therapeutic combinations (EMPEROR-Reduced): a post-hoc analysis of a randomised, double-blind trial.

The lancet. Diabetes & endocrinology

Verma S, Dhingra NK, Butler J, Anker SD, Ferreira JP, Filippatos G, Januzzi JL, Lam CSP, Sattar N, Peil B, Nordaby M, Brueckmann M, Pocock SJ, Zannad F, Packer M.
PMID: 34861154
Lancet Diabetes Endocrinol. 2022 Jan;10(1):35-45. doi: 10.1016/S2213-8587(21)00292-8. Epub 2021 Nov 30.

BACKGROUND: It is important to evaluate whether a new treatment for heart failure with reduced ejection fraction (HFrEF) provides additive benefit to background foundational treatments. As such, we aimed to evaluate the efficacy and safety of empagliflozin in patients...

Showing 445 to 455 of 455 entries